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Volumn 26, Issue 28, 2008, Pages 4595-4602

Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: A cancer and leukemia group B study

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; DAUNORUBICIN; ETOPOSIDE; FLT3 LIGAND; VALSPODAR;

EID: 53749101166     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2007.15.2058     Document Type: Article
Times cited : (227)

References (51)
  • 1
    • 0037114753 scopus 로고    scopus 로고
    • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461)
    • Byrd JC, Mrózek K, Dodge RK, et al: Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461). Blood 100:4325-4336, 2002
    • (2002) Blood , vol.100 , pp. 4325-4336
    • Byrd, J.C.1    Mrózek, K.2    Dodge, R.K.3
  • 2
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
    • Grimwade D, Walker H, Oliver F, et al: The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. Blood 92:2322-2333, 1998
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 3
    • 0034672269 scopus 로고    scopus 로고
    • Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/ Eastern Cooperative Oncology Group study
    • Slovak ML, Kopecky KJ, Cassileth PA, et al: Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/ Eastern Cooperative Oncology Group study. Blood 96:4075-4083, 2000
    • (2000) Blood , vol.96 , pp. 4075-4083
    • Slovak, M.L.1    Kopecky, K.J.2    Cassileth, P.A.3
  • 4
    • 33846230449 scopus 로고    scopus 로고
    • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
    • Mrózek K, Marcucci G, Paschka P, et al: Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification? Blood 109:431-448, 2007
    • (2007) Blood , vol.109 , pp. 431-448
    • Mrózek, K.1    Marcucci, G.2    Paschka, P.3
  • 5
    • 34548234969 scopus 로고    scopus 로고
    • High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
    • Marcucci G, Maharry K, Whitman SP, et al: High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study. J Clin Oncol 25:3337-3343, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 3337-3343
    • Marcucci, G.1    Maharry, K.2    Whitman, S.P.3
  • 6
    • 0025099787 scopus 로고
    • Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
    • Call KM, Glaser T, Ito CY, et al: Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 60:509-520, 1990
    • (1990) Cell , vol.60 , pp. 509-520
    • Call, K.M.1    Glaser, T.2    Ito, C.Y.3
  • 7
    • 34247579714 scopus 로고    scopus 로고
    • A tumor suppressor and oncogene: The WT1 story
    • Yang L, Han Y, Suarez Saiz F, et al: A tumor suppressor and oncogene: The WT1 story. Leukemia 21:868-876, 2007
    • (2007) Leukemia , vol.21 , pp. 868-876
    • Yang, L.1    Han, Y.2    Suarez Saiz, F.3
  • 8
    • 0025288793 scopus 로고
    • An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
    • Haber DA, Buckler AJ, Glaser T, et al: An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell 61:1257-1269, 1990
    • (1990) Cell , vol.61 , pp. 1257-1269
    • Haber, D.A.1    Buckler, A.J.2    Glaser, T.3
  • 9
    • 34250784012 scopus 로고    scopus 로고
    • The role of the Wilms tumour gene (WT1) in normal and malignant haematopoiesis
    • Ariyaratana S, Loeb DM: The role of the Wilms tumour gene (WT1) in normal and malignant haematopoiesis. Expert Rev Mol Med 14:1-17, 2007
    • (2007) Expert Rev Mol Med , vol.14 , pp. 1-17
    • Ariyaratana, S.1    Loeb, D.M.2
  • 10
    • 9244237089 scopus 로고    scopus 로고
    • Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis
    • Yamagami T, Sugiyama H, Inoue K, et al: Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis. Blood 87:2878-2884, 1996
    • (1996) Blood , vol.87 , pp. 2878-2884
    • Yamagami, T.1    Sugiyama, H.2    Inoue, K.3
  • 11
    • 33645729159 scopus 로고    scopus 로고
    • AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1
    • Nishida S, Hosen N, Shirakata T, et al: AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. Blood 107:3303-3312, 2006
    • (2006) Blood , vol.107 , pp. 3303-3312
    • Nishida, S.1    Hosen, N.2    Shirakata, T.3
  • 12
    • 0030737629 scopus 로고    scopus 로고
    • High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome
    • Bergmann L, Miething C, Maurer U, et al: High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome. Blood 90:1217-1225, 1997
    • (1997) Blood , vol.90 , pp. 1217-1225
    • Bergmann, L.1    Miething, C.2    Maurer, U.3
  • 13
    • 3943088995 scopus 로고    scopus 로고
    • Prognostic implications of Wilms' tumor gene (WT1) expression in patients with de novo acute myeloid leukemia
    • Barragán E, Cervera J, Bolufer P, et al: Prognostic implications of Wilms' tumor gene (WT1) expression in patients with de novo acute myeloid leukemia. Haematologica 89:926-933, 2004
    • (2004) Haematologica , vol.89 , pp. 926-933
    • Barragán, E.1    Cervera, J.2    Bolufer, P.3
  • 14
    • 3242888125 scopus 로고    scopus 로고
    • Multiplex real-time RT-PCR for prospective evaluation of WT1 and fusion gene transcripts in newly diagnosed de novo acute myeloid leukemia
    • Yanada M, Terakura S, Yokozawa T, et al: Multiplex real-time RT-PCR for prospective evaluation of WT1 and fusion gene transcripts in newly diagnosed de novo acute myeloid leukemia. Leuk Lymphoma 45:1803-1808, 2004
    • (2004) Leuk Lymphoma , vol.45 , pp. 1803-1808
    • Yanada, M.1    Terakura, S.2    Yokozawa, T.3
  • 15
    • 23844458023 scopus 로고    scopus 로고
    • Prognostic impact of RT-PCR-based quantification of WT1 gene expression during MRD monitoring of acute myeloid leukemia
    • Weisser M, Kern W, Rauhut S, et al: Prognostic impact of RT-PCR-based quantification of WT1 gene expression during MRD monitoring of acute myeloid leukemia. Leukemia 19:1416-1423, 2005
    • (2005) Leukemia , vol.19 , pp. 1416-1423
    • Weisser, M.1    Kern, W.2    Rauhut, S.3
  • 16
    • 33645746149 scopus 로고    scopus 로고
    • High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia
    • Lapillonne H, Renneville A, Auvrignon A, et al: High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia. J Clin Oncol 24:1507-1515, 2006
    • (2006) J Clin Oncol , vol.24 , pp. 1507-1515
    • Lapillonne, H.1    Renneville, A.2    Auvrignon, A.3
  • 17
    • 34447279071 scopus 로고    scopus 로고
    • Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia
    • Rodrigues PC, Oliveira SN, Viana MB, et al: Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia. Pediatr Blood Cancer 49:133-138, 2007
    • (2007) Pediatr Blood Cancer , vol.49 , pp. 133-138
    • Rodrigues, P.C.1    Oliveira, S.N.2    Viana, M.B.3
  • 18
    • 0030891372 scopus 로고    scopus 로고
    • A clinical overview of WT1 gene mutations
    • Little M, Wells C: A clinical overview of WT1 gene mutations. Hum Mutat 9:209-225, 1997
    • (1997) Hum Mutat , vol.9 , pp. 209-225
    • Little, M.1    Wells, C.2
  • 19
  • 20
    • 33749266701 scopus 로고    scopus 로고
    • Syndromes and constitutional chromosomal abnormalities associated with Wilms tumour
    • Scott RH, Stiller CA, Walker L, et al: Syndromes and constitutional chromosomal abnormalities associated with Wilms tumour. J Med Genet 43:705-715, 2006
    • (2006) J Med Genet , vol.43 , pp. 705-715
    • Scott, R.H.1    Stiller, C.A.2    Walker, L.3
  • 21
    • 0033037252 scopus 로고    scopus 로고
    • Mutation of the WT1 gene in myelodysplastic syndrome and acute myeloid leukaemia post myelodysplastic syndrome
    • Mori N, Okada M, Motoji T, et al: Mutation of the WT1 gene in myelodysplastic syndrome and acute myeloid leukaemia post myelodysplastic syndrome. Br J Haematol 105:844-845, 1999
    • (1999) Br J Haematol , vol.105 , pp. 844-845
    • Mori, N.1    Okada, M.2    Motoji, T.3
  • 22
    • 0033935354 scopus 로고    scopus 로고
    • Mutation analysis of the WT1 gene in secondary leukemia
    • Takahashi T, Yamamoto R, Tanaka K, et al: Mutation analysis of the WT1 gene in secondary leukemia. Leukemia 14:1316-1317, 2000
    • (2000) Leukemia , vol.14 , pp. 1316-1317
    • Takahashi, T.1    Yamamoto, R.2    Tanaka, K.3
  • 23
    • 0031693630 scopus 로고    scopus 로고
    • Mutation analysis of the WT1 gene in myelodysplastic syndromes
    • Hosoya N, Miyagawa K, Mitani K, et al: Mutation analysis of the WT1 gene in myelodysplastic syndromes. Jpn J Cancer Res 89:821-824, 1998
    • (1998) Jpn J Cancer Res , vol.89 , pp. 821-824
    • Hosoya, N.1    Miyagawa, K.2    Mitani, K.3
  • 24
    • 0032522974 scopus 로고    scopus 로고
    • Wilms' tumor (WT1) gene mutations occur mainly in acute myeloid leukemia and may confer drug resistance
    • King-Underwood L, Pritchard-Jones K: Wilms' tumor (WT1) gene mutations occur mainly in acute myeloid leukemia and may confer drug resistance. Blood 91:2961-2968, 1998
    • (1998) Blood , vol.91 , pp. 2961-2968
    • King-Underwood, L.1    Pritchard-Jones, K.2
  • 25
    • 0032933499 scopus 로고    scopus 로고
    • Mutations of the WT1 gene in childhood nonlymphoid hematological malignancies
    • Miyagawa K, Hayashi Y, Fukuda T, et al: Mutations of the WT1 gene in childhood nonlymphoid hematological malignancies. Genes Chromosomes Cancer 25:176-183, 1999
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 176-183
    • Miyagawa, K.1    Hayashi, Y.2    Fukuda, T.3
  • 26
    • 33847238455 scopus 로고    scopus 로고
    • Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML
    • Summers K, Stevens J, Kakkas I, et al: Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML. Leukemia 21:550-551, 2007
    • (2007) Leukemia , vol.21 , pp. 550-551
    • Summers, K.1    Stevens, J.2    Kakkas, I.3
  • 27
    • 16544385074 scopus 로고    scopus 로고
    • Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: Final induction results of Cancer and Leukemia Group B study 9621
    • Kolitz JE, George SL, Dodge RK, et al: Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: Final induction results of Cancer and Leukemia Group B study 9621. J Clin Oncol 22:4290-4301, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 4290-4301
    • Kolitz, J.E.1    George, S.L.2    Dodge, R.K.3
  • 28
    • 33747413754 scopus 로고    scopus 로고
    • A randomized comparison of induction therapy for untreated acute myeloid leukemia (AML) in patients < 60 years using P-glycoprotein (Pgp) modulation with valspodar (PSC833): Preliminary results of Cancer and Leukemia Group B study 19808
    • abstr 407
    • Kolitz JE, George SL, Marcucci G, et al: A randomized comparison of induction therapy for untreated acute myeloid leukemia (AML) in patients < 60 years using P-glycoprotein (Pgp) modulation with valspodar (PSC833): Preliminary results of Cancer and Leukemia Group B study 19808. Blood 106:122a, 2005 (abstr 407)
    • (2005) Blood , vol.106
    • Kolitz, J.E.1    George, S.L.2    Marcucci, G.3
  • 29
    • 3242789449 scopus 로고    scopus 로고
    • Prevalence of WT1 mutations in a large cohort of patients with steroid-resistant and steroid-sensitive nephrotic syndrome
    • Ruf RG, Schultheiss M, Lichtenberger A, et al: Prevalence of WT1 mutations in a large cohort of patients with steroid-resistant and steroid-sensitive nephrotic syndrome. Kidney Int 66:564-570, 2004
    • (2004) Kidney Int , vol.66 , pp. 564-570
    • Ruf, R.G.1    Schultheiss, M.2    Lichtenberger, A.3
  • 30
    • 33747822319 scopus 로고    scopus 로고
    • WT1 mutations in nephrotic syndrome revisited: High prevalence in young girls, associations and renal phenotypes
    • Aucella F, Bisceglia L, De Bonis P, et al: WT1 mutations in nephrotic syndrome revisited: High prevalence in young girls, associations and renal phenotypes. Pediatr Nephrol 21:1393-1398, 2006
    • (2006) Pediatr Nephrol , vol.21 , pp. 1393-1398
    • Aucella, F.1    Bisceglia, L.2    De Bonis, P.3
  • 31
    • 0038059078 scopus 로고    scopus 로고
    • The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: Impact for diagnostics and pharmacogenetics
    • Frueh FW, Noyer-Weidner M: The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: Impact for diagnostics and pharmacogenetics. Clin Chem Lab Med 41:452-461, 2003
    • (2003) Clin Chem Lab Med , vol.41 , pp. 452-461
    • Frueh, F.W.1    Noyer-Weidner, M.2
  • 32
    • 0037114829 scopus 로고    scopus 로고
    • Fröhling S, Schlenk RF, Breitruck J, et al: Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: A study of the AML Study Group Ulm. Blood 100:4372-4380, 2002
    • Fröhling S, Schlenk RF, Breitruck J, et al: Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: A study of the AML Study Group Ulm. Blood 100:4372-4380, 2002
  • 33
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C, Steudel C, Mohr B, et al: Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis. Blood 99:4326-4335, 2002
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 34
    • 0035871889 scopus 로고    scopus 로고
    • Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
    • Yamamoto Y, Kiyoi H, Nakano Y, et al: Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood 97:2434-2439, 2001
    • (2001) Blood , vol.97 , pp. 2434-2439
    • Yamamoto, Y.1    Kiyoi, H.2    Nakano, Y.3
  • 35
    • 38949212204 scopus 로고    scopus 로고
    • FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications
    • Whitman SP, Ruppert AS, Radmacher MD, et al: FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications. Blood 111:1552-1559, 2008
    • (2008) Blood , vol.111 , pp. 1552-1559
    • Whitman, S.P.1    Ruppert, A.S.2    Radmacher, M.D.3
  • 36
    • 0031984414 scopus 로고    scopus 로고
    • Rearrangement of ALL1 (MLL) in acute myeloid leukemia with normal cytogenetics
    • Caligiuri MA, Strout MP, Lawrence D, et al: Rearrangement of ALL1 (MLL) in acute myeloid leukemia with normal cytogenetics. Cancer Res 58:55-59, 1998
    • (1998) Cancer Res , vol.58 , pp. 55-59
    • Caligiuri, M.A.1    Strout, M.P.2    Lawrence, D.3
  • 37
    • 22044452929 scopus 로고    scopus 로고
    • The MLL partial tandem duplication: Evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy
    • Whitman SP, Liu S, Vukosavljevic T, et al: The MLL partial tandem duplication: Evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy. Blood 106:345-352, 2005
    • (2005) Blood , vol.106 , pp. 345-352
    • Whitman, S.P.1    Liu, S.2    Vukosavljevic, T.3
  • 38
    • 28444473100 scopus 로고    scopus 로고
    • Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: Interaction with other gene mutations
    • Döhner K, Schlenk RF, Habdank M, et al: Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: Interaction with other gene mutations. Blood 106:3740-3746, 2005
    • (2005) Blood , vol.106 , pp. 3740-3746
    • Döhner, K.1    Schlenk, R.F.2    Habdank, M.3
  • 39
    • 1442356729 scopus 로고    scopus 로고
    • CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: Prognostic relevance and analysis of cooperating mutations
    • Fröhling S, Schlenk RF, Stolze I, et al: CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: Prognostic relevance and analysis of cooperating mutations. J Clin Oncol 22:624-633, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 624-633
    • Fröhling, S.1    Schlenk, R.F.2    Stolze, I.3
  • 40
    • 33644830601 scopus 로고    scopus 로고
    • Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: A Cancer and Leukemia Group B study
    • Marcucci G, Baldus CD, Ruppert AS, et al: Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: A Cancer and Leukemia Group B study. J Clin Oncol 23:9234-9242, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 9234-9242
    • Marcucci, G.1    Baldus, C.D.2    Ruppert, A.S.3
  • 41
    • 0041440085 scopus 로고    scopus 로고
    • BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: A Cancer and Leukemia Group B Study
    • Baldus CD, Tanner SM, Ruppert AS, et al: BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: A Cancer and Leukemia Group B Study. Blood 102:1613-1618, 2003
    • (2003) Blood , vol.102 , pp. 1613-1618
    • Baldus, C.D.1    Tanner, S.M.2    Ruppert, A.S.3
  • 42
    • 0025261428 scopus 로고
    • Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia
    • Cheson BD, Cassileth PA, Head DR, et al: Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia. J Clin Oncol 8:813-819, 1990
    • (1990) J Clin Oncol , vol.8 , pp. 813-819
    • Cheson, B.D.1    Cassileth, P.A.2    Head, D.R.3
  • 44
    • 19944427850 scopus 로고    scopus 로고
    • Falini B, Mecucci C, Tiacci E, et al: Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype [erratum appears in N Engl J Med 352:740, 2005]. N Engl J Med 352:254-266, 2005
    • Falini B, Mecucci C, Tiacci E, et al: Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype [erratum appears in N Engl J Med 352:740, 2005]. N Engl J Med 352:254-266, 2005
  • 45
    • 24144494881 scopus 로고    scopus 로고
    • Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia
    • Suzuki T, Kiyoi H, Ozeki K, et al: Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. Blood 106:2854-2861, 2005
    • (2005) Blood , vol.106 , pp. 2854-2861
    • Suzuki, T.1    Kiyoi, H.2    Ozeki, K.3
  • 46
    • 28444449081 scopus 로고    scopus 로고
    • Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
    • Schnittger S, Schoch C, Kern W, et al: Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood 106:3733-3739, 2005
    • (2005) Blood , vol.106 , pp. 3733-3739
    • Schnittger, S.1    Schoch, C.2    Kern, W.3
  • 47
    • 33646557337 scopus 로고    scopus 로고
    • Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)
    • Thiede C, Koch S, Creutzig E, et al: Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML). Blood 107:4011-4020, 2006
    • (2006) Blood , vol.107 , pp. 4011-4020
    • Thiede, C.1    Koch, S.2    Creutzig, E.3
  • 48
    • 33644866304 scopus 로고    scopus 로고
    • BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: Prognostic implications
    • Baldus CD, Thiede C, Soucek S, et al: BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: Prognostic implications. J Clin Oncol 24:790-797, 2006
    • (2006) J Clin Oncol , vol.24 , pp. 790-797
    • Baldus, C.D.1    Thiede, C.2    Soucek, S.3
  • 49
    • 0025992044 scopus 로고
    • Alternative splicing and genomic structure of the Wilms tumor gene WT1
    • Haber DA, Sohn RL, Buckler AJ, et al: Alternative splicing and genomic structure of the Wilms tumor gene WT1. Proc Natl Acad Sci U S A 88:9618-9622, 1991
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 9618-9622
    • Haber, D.A.1    Sohn, R.L.2    Buckler, A.J.3
  • 50
    • 34548500557 scopus 로고    scopus 로고
    • Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
    • Stoll R, Lee BM, Debler EW, et al: Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA. J Mol Biol 372:1227-1245, 2007
    • (2007) J Mol Biol , vol.372 , pp. 1227-1245
    • Stoll, R.1    Lee, B.M.2    Debler, E.W.3
  • 51
    • 0034652714 scopus 로고    scopus 로고
    • Expression of the Wilms' tumor suppressor gene, WT1, reduces the tumorigenicity of the leukemic cell line M1 in C.B-17 scid/scid mice
    • Smith SI, Down M, Boyd AW, et al: Expression of the Wilms' tumor suppressor gene, WT1, reduces the tumorigenicity of the leukemic cell line M1 in C.B-17 scid/scid mice. Cancer Res 60:808-814, 2000
    • (2000) Cancer Res , vol.60 , pp. 808-814
    • Smith, S.I.1    Down, M.2    Boyd, A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.