DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 5, 2011, Pages 839-849

  Hupkes, Marlinda ^a   van Someren, Eugene P ^a   Middelkamp, Sjors H A ^a   Piek, Ester ^a   van Zoelen, Everardus J ^a   Dechering, Koen J ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

5 Azacytidine; Bone morphogenetic protein 2; Differentiation; DNA methylation; Myoblast; Osteoblast

Indexed keywords

ALKALINE PHOSPHATASE; AZACITIDINE; BISULFITE; BONE MORPHOGENETIC PROTEIN 2; GROWTH FACTOR; MYOD1 PROTEIN; PROTEIN ACADL; PROTEIN ACTG1; PROTEIN ANK; PROTEIN GRIK3; PROTEIN ITGA6; PROTEIN MYOG; PROTEIN PDIA2; PROTEIN RASSF3; PROTEIN SP7; PROTEIN TNNC2; PROTEIN USP15; PROTEIN ZC3H13; RNA POLYMERASE II; TRANSCRIPTION FACTOR DLX5; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL LINEAGE; CELL TYPE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; ENZYME ACTIVITY; GENOME ANALYSIS; MESENCHYME CELL; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; UPREGULATION;

ADIPOGENESIS; ANIMALS; AZACITIDINE; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELL LINEAGE; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; HOMEODOMAIN PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESENCHYMAL STEM CELLS; MICE; MUSCLE DEVELOPMENT; OSTEOGENESIS; PROMOTER REGIONS, GENETIC; REPRODUCIBILITY OF RESULTS; RNA POLYMERASE II; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 79955662450     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.01.022     Document Type: Article

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