메뉴 건너뛰기




Volumn 63, Issue 2, 2011, Pages 119-131

Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus

Author keywords

Alloxan; Electrolyzed reduced water; HIT T15 cells; Reactive oxygen species; Type 1 diabetes mellitus

Indexed keywords

ALLOXAN; ANTIDIABETIC AGENT; ANTIOXIDANT; CELL DNA; ELECTROLYZED REDUCED WATER; GLUCOSE; INSULIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; WATER;

EID: 79955903247     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-010-9317-6     Document Type: Article
Times cited : (38)

References (53)
  • 1
    • 0033536428 scopus 로고    scopus 로고
    • A review of modern transition-metal nanoclusters: Their syn
    • thesis, characterization, and application in catalysis.
    • Aiken JD III, Finke RG (1999) A review of modern transition-metal nanoclusters: their synthesis, characterization, and application in catalysis. J Mol Catal A Chem 145:1-44
    • (1999) J Mol Catal A Chem , vol.145 , pp. 1-44
    • Aiken III, J.D.1    Finke, R.G.2
  • 2
    • 0036270993 scopus 로고    scopus 로고
    • DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: Fail-safe protection against carcinogenesis
    • DOI 10.1016/S1383-5742(02)00009-1, PII S1383574202000091
    • Bernstein C, Bernstein H, Payne CM, Garewal H (2002) DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat Res 511:145-178 (Pubitemid 34621252)
    • (2002) Mutation Research - Reviews in Mutation Research , vol.511 , Issue.2 , pp. 145-178
    • Bernstein, C.1    Bernstein, H.2    Payne, C.M.3    Garewal, H.4
  • 3
    • 33947726341 scopus 로고    scopus 로고
    • Moving towards efficient therapies in type 1 diabetes: To combine or not to combine?
    • Bresson D, Von Herrath M (2007) Moving towards efficient therapies in type 1 diabetes: to combine or not to combine? Autoimmun Rev 6:315-322
    • (2007) Autoimmun Rev , vol.6 , pp. 315-322
    • Bresson, D.1    Von Herrath, M.2
  • 4
    • 29744458623 scopus 로고    scopus 로고
    • Influence of oxygen concentration on redox cycling of alloxan and dialuric acid
    • DOI 10.1055/s-2005-921093
    • Brömme HJ, Weinandy R, Peschke E (2005) Influence of oxygen concentration on redox cycling of alloxan and dialuric acid. Horm Metab Res 37:729-733 (Pubitemid 43028073)
    • (2005) Hormone and Metabolic Research , vol.37 , Issue.12 , pp. 729-733
    • Bromme, H.J.1    Weinandy, R.2    Peschke, E.3
  • 5
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: Many differences, few similarities
    • Cnop M, Welsh N, Jonas J-C, Jörns A, Lenzen S, Eizirik DL (2005) Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54:97-107
    • (2005) Diabetes , vol.54 , pp. 97-107
    • Cnop, M.1    Welsh, N.2    Jonas, J.-C.3    Jörns, A.4    Lenzen, S.5    Eizirik, D.L.6
  • 6
    • 0036644215 scopus 로고    scopus 로고
    • Regulation and measurement of oxidative stress in apoptosis
    • DOI 10.1016/S0022-1759(02)00070-4, PII S0022175902000704
    • Curtin JF, Donovan M, Cotter TG (2002) Regulation and measurement of oxidative stress in apoptosis. J Immunol Methods 265:49-72 (Pubitemid 34628804)
    • (2002) Journal of Immunological Methods , vol.265 , Issue.1-2 , pp. 49-72
    • Curtin, J.F.1    Donovan, M.2    Cotter, T.G.3
  • 7
    • 0035124874 scopus 로고    scopus 로고
    • β-cell apoptosis and defense mechanisms. Lessons from type 1 diabetes
    • Eizirik DL, Darville MI (2001) β-cell apoptosis and defense mechanisms. Lessons from type 1 diabetes. Diabetes 50:S64-S69
    • (2001) Diabetes , vol.50
    • Eizirik, D.L.1    Darville, M.I.2
  • 8
    • 22144469767 scopus 로고    scopus 로고
    • Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats
    • DOI 10.1016/j.phrs.2005.04.003, PII S1043661805000873
    • El-Alfy AT, Ahmed AAE, Fatani AJ (2005) Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats. Pharmacol Res 52:264-270 (Pubitemid 40981928)
    • (2005) Pharmacological Research , vol.52 , Issue.3 , pp. 264-270
    • El-Alfy, A.T.1    Ahmed, A.A.E.2    Fatani, A.J.3
  • 9
    • 0036434465 scopus 로고    scopus 로고
    • Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan
    • DOI 10.1007/s00125-002-0955-x
    • Elsner M, Tiedge M, Guldbakke B, Munday R, Lenzen S (2002) Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan. Diabetologia 45:1542-1549 (Pubitemid 35352048)
    • (2002) Diabetologia , vol.45 , Issue.11 , pp. 1542-1549
    • Elsner, M.1    Tiedge, M.2    Guldbakke, B.3    Munday, R.4    Lenzen, S.5
  • 10
    • 33746766202 scopus 로고    scopus 로고
    • Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin-producing cells
    • DOI 10.1016/j.freeradbiomed.2006.06.002, PII S0891584906003649
    • Elsner M, Gurgul-Convey E, Lenzen S (2006) Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin-producing cells. Free Radic Biol Med 41:825-834 (Pubitemid 44163416)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.5 , pp. 825-834
    • Elsner, M.1    Gurgul-Convey, E.2    Lenzen, S.3
  • 11
    • 34547768785 scopus 로고    scopus 로고
    • Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress
    • DOI 10.1016/j.bbrc.2007.07.088, PII S0006291X07015525
    • Fukuda K, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, Ohta S (2007) Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. Biochem Biophys Res Commun 361:670-674 (Pubitemid 47238041)
    • (2007) Biochemical and Biophysical Research Communications , vol.361 , Issue.3 , pp. 670-674
    • Fukuda, K.-I.1    Asoh, S.2    Ishikawa, M.3    Yamamoto, Y.4    Ohsawa, I.5    Ohta, S.6
  • 12
    • 1242340281 scopus 로고    scopus 로고
    • Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro
    • Gai W, Schott-Ohly P, Schulte im Walde S, Gleichmann H (2004) Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro. Exp Clin Endocrinol Diabetes 112:29-37
    • (2004) Exp Clin Endocrinol Diabetes , vol.112 , pp. 29-37
    • Gai, W.1    Schott-Ohly, P.2    Schulte Im Walde, S.3    Gleichmann, H.4
  • 13
    • 4344716628 scopus 로고    scopus 로고
    • Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines
    • DOI 10.2337/diabetes.53.9.2271
    • Gurgul E, Lortz S, Tiedge M, Jörns A, Lenzen S (2004) Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines. Diabetes 53:2271-2280 (Pubitemid 39145580)
    • (2004) Diabetes , vol.53 , Issue.9 , pp. 2271-2280
    • Gurgul, E.1    Lortz, S.2    Tiedge, M.3    Jorns, A.4    Lenzen, S.5
  • 16
    • 21344471092 scopus 로고    scopus 로고
    • Immune cell infiltration, cytokine expression, and β-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm-iddm rat
    • DOI 10.2337/diabetes.54.7.2041
    • Jörns A, Günther A, Hedrich H-J, Wedekind D, Tiedge M, Lenzen S (2005) Immune cell infiltration, cytokine expression, and β-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm- iddm rat. Diabetes 54:2041-2052 (Pubitemid 40911267)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 2041-2052
    • Jorns, A.1    Gunther, A.2    Hedrich, H.-J.3    Wedekind, D.4    Tiedge, M.5    Lenzen, S.6
  • 17
    • 34249821634 scopus 로고    scopus 로고
    • Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide
    • DOI 10.1080/10715760601169679, PII 778898968
    • Kajita M, Hikosaka K, Iitsuka M, Kanayama A, Toshima N, Miyamoto Y (2007) Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide. Free Radical Res 41:615-626 (Pubitemid 46845581)
    • (2007) Free Radical Research , vol.41 , Issue.6 , pp. 615-626
    • Kajita, M.1    Hikosaka, K.2    Iitsuka, M.3    Kanayama, A.4    Toshima, N.5    Miyamoto, Y.6
  • 19
    • 0034084572 scopus 로고    scopus 로고
    • The beta cell in autoimmune diabetes: Many mechanisms and pathways of loss
    • DOI 10.1016/S1043-2760(99)00210-6, PII S1043276099002106
    • Kay TW, Thomas HE, Harrison LC, Allison J (2000) The beta cell in autoimmune diabetes: many mechanisms and pathways of loss. Trends Endocrinol Metab 11:11-15 (Pubitemid 30395454)
    • (2000) Trends in Endocrinology and Metabolism , vol.11 , Issue.1 , pp. 11-15
    • Kay, T.W.H.1    Thomas, H.E.2    Harrison, L.C.3    Allison, J.4
  • 20
    • 33750523005 scopus 로고    scopus 로고
    • Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice
    • DOI 10.1016/j.lfs.2006.07.027, PII S0024320506005923
    • Kim M-J, Kim HK (2006) Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice. Life Sci 79:2288-2292 (Pubitemid 44666066)
    • (2006) Life Sciences , vol.79 , Issue.24 , pp. 2288-2292
    • Kim, M.-J.1    Kim, H.K.2
  • 22
    • 0003737606 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus: Islet changes in relation to etiology and pathogenesis
    • Klöppel G, Clemens A (1997) Insulin-dependent diabetes mellitus: islet changes in relation to etiology and pathogenesis. Endocr Pathol 8:273-282 (Pubitemid 127718205)
    • (1997) Endocrine Pathology , vol.8 , Issue.4 , pp. 273-282
    • Kloppel, G.1    Clemens, A.2
  • 24
    • 0025823868 scopus 로고
    • Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its n-methyl derivatives and a comparison with ninhydrin
    • Lenzen S, Munday R (1991) Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its n-methyl derivatives and a comparison with ninhydrin. Biochem Pharmacol 42:1385-1391
    • (1991) Biochem Pharmacol , vol.42 , pp. 1385-1391
    • Lenzen, S.1    Munday, R.2
  • 25
    • 0029984682 scopus 로고    scopus 로고
    • Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
    • DOI 10.1016/0891-5849(96)02051-5
    • Lenzen S, Drinkgern J, Tiedge M (1996) Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med 20:463-466 (Pubitemid 26077870)
    • (1996) Free Radical Biology and Medicine , vol.20 , Issue.3 , pp. 463-466
    • Lenzen, S.1    Drinkgern, J.2    Tiedge, M.3
  • 27
    • 0037443701 scopus 로고    scopus 로고
    • Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines
    • Lortz S, Tiedge M (2003) Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines. Free Radic Biol Med 34:683-688
    • (2003) Free Radic Biol Med , vol.34 , pp. 683-688
    • Lortz, S.1    Tiedge, M.2
  • 28
    • 23844470618 scopus 로고    scopus 로고
    • Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines
    • DOI 10.1007/s00125-005-1822-3
    • Lortz S, Gurgul-Convey E, Lenzen S, Tiedge M (2005) Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines. Diabetologia 48:1541-1548 (Pubitemid 41175507)
    • (2005) Diabetologia , vol.48 , Issue.8 , pp. 1541-1548
    • Lortz, S.1    Gurgul-Convey, E.2    Lenzen, S.3    Tiedge, M.4
  • 29
    • 33846670732 scopus 로고    scopus 로고
    • Finding new treatments for diabetes - How many, how fast...how good?
    • Nathan DM (2007) Finding new treatments for diabetes - how many, how fast...how good? N Engl J Med 356:437-440
    • (2007) N Engl J Med , vol.356 , pp. 437-440
    • Nathan, D.M.1
  • 30
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139:271-279
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 31
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 356:2457-2471 (Pubitemid 46919772)
    • (2007) New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 34
    • 34250325126 scopus 로고    scopus 로고
    • Mechanisms for oxidative stress in diabetic cardiovascular disease
    • DOI 10.1089/ars.2007.1595
    • Pennathur S, Heinecke JW (2007) Mechanisms for oxidative stress in diabetic cardiovascular disease. Antioxid Redox Signal 9:955-969 (Pubitemid 46919596)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.7 , pp. 955-969
    • Pennathur, S.1    Heinecke, J.W.2
  • 36
    • 33745350055 scopus 로고    scopus 로고
    • Ascorbate-mediated iron release from ferritin in the presence of alloxan
    • DOI 10.1007/s10534-005-1300-x
    • Sakurai K, Nabeyama A, Fujimoto Y (2006) Ascorbate-mediated iron release from ferritin in the presence of alloxan. Biometals 19:323-333 (Pubitemid 43946172)
    • (2006) BioMetals , vol.19 , Issue.3 , pp. 323-333
    • Sakurai, K.1    Nabeyama, A.2    Fujimoto, Y.3
  • 38
    • 0037700633 scopus 로고    scopus 로고
    • Reduced water for prevention of diseases
    • Shirahata S, Teruya K, Katakura Y (eds) Kluwer Academic Publishers, The Netherlands
    • Shirahata S (2002) Reduced water for prevention of diseases. In: Shirahata S, Teruya K, Katakura Y (eds) Animal cell technology: basic & applied aspects, vol 12. Kluwer Academic Publishers, The Netherlands, pp 25-30
    • (2002) Animal Cell Technology: Basic & Applied Aspects , vol.12 , pp. 25-30
    • Shirahata, S.1
  • 41
    • 2542440824 scopus 로고    scopus 로고
    • Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line
    • DOI 10.1007/s00109-004-0533-4
    • Sigfrid LA, Cunningham JM, Beeharry N, Borg LAH, Hernandez ALR, Carlsson C, Bone AJ, Green IC (2004) Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line. J Mol Med 82:325-335 (Pubitemid 38680290)
    • (2004) Journal of Molecular Medicine , vol.82 , Issue.5 , pp. 325-335
    • Sigfrid, L.A.1    Cunningham, J.M.2    Beeharry, N.3    Hakan, B.L.A.4    Rosales, H.A.L.5    Carlsson, C.6    Bone, A.J.7    Green, I.C.8
  • 42
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas
    • Szkudelski T (2001) The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas. Physiol Res 50:536-546
    • (2001) Physiol Res , vol.50 , pp. 536-546
    • Szkudelski, T.1
  • 44
    • 0019158004 scopus 로고
    • Induction of diabetes by cumulative environmental insults from viruses and chemicals
    • DOI 10.1038/288383a0
    • Toniolo A, Onodera T, Yoon J-W, Notkins AL (1980) Induction of diabetes by cumulative environmental insults from viruses and chemicals. Nature 288:383-385 (Pubitemid 11169014)
    • (1980) Nature , vol.288 , Issue.5789 , pp. 383-385
    • Toniolo, A.1    Onodera, T.2    Yoon, J.W.3    Notkins, A.L.4
  • 46
    • 0030744077 scopus 로고    scopus 로고
    • Glutathione dependent reduction of alloxan to dialuric acid catalyzed by thioltransferase (glutaredoxin): A possible role for thioltransferase in alloxan toxicity
    • DOI 10.1016/S0891-5849(97)00001-4, PII S0891584997000014
    • Washburn MP, Wells WW (1997) Glutathione dependent reduction of alloxan to dialuric acid catalyzed by thioltransferase (glutaredoxin): a possible role for thioltransferase in alloxane toxicity. Free Radic Biol Med 23:563-570 (Pubitemid 27287340)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.4 , pp. 563-570
    • Washburn, M.P.1    Wells, W.W.2
  • 47
    • 0030714094 scopus 로고    scopus 로고
    • Transition metal nanocluster formation kinetic and mechanistic studies. A new mechanism when hydrogen is the reductant: Slow, continuous nucleation and fast autocatalytic surface growth
    • DOI 10.1021/ja9705102
    • Watzky MA, Finke RG (1997) Transition metal nanocluster formation kinetic and mechanistic studies. A new mechanism when hydrogen is the reductant: slow, continuous nucleation and fast autocatalytic surface growth. J Am Chem Soc 119:10382-10400 (Pubitemid 27487978)
    • (1997) Journal of the American Chemical Society , vol.119 , Issue.43 , pp. 10382-10400
    • Watzky, M.A.1    Finke, R.G.2
  • 48
    • 0024520376 scopus 로고
    • Glutathione-mediated redox cycling of alloxan
    • Winterbourn CC, Munday R (1989) Glutathione-mediated redox cycling of alloxan. Biochem Pharmacol 38:271-2771
    • (1989) Biochem Pharmacol , vol.38 , pp. 271-2771
    • Winterbourn, C.C.1    Munday, R.2
  • 50
    • 34249905512 scopus 로고    scopus 로고
    • Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men
    • DOI 10.2337/dc06-2606
    • Yaturu S, Bryant B, Jain SK (2007) Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men. Diabetes Care 30:1574-1576 (Pubitemid 46876524)
    • (2007) Diabetes Care , vol.30 , Issue.6 , pp. 1574-1576
    • Yaturu, S.1    Bryant, B.2    Jain, S.K.3
  • 52
    • 0029072441 scopus 로고
    • Insulinoma cells in culture show pronounced sensitivity to alloxan-induced oxidative stress
    • Zhang H, Ollinger K, Brunk U (1995) Insulinoma cells in culture show pronounced sensitivity to alloxan-induced oxidative stress. Diabetologia 38:635-641
    • (1995) Diabetologia , vol.38 , pp. 635-641
    • Zhang, H.1    Ollinger, K.2    Brunk, U.3
  • 53
    • 0042572432 scopus 로고    scopus 로고
    • In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage
    • Zhang H-N, Hea J-H, Yuanb L, Lin Z-B (2003) In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage. Life Sci 73:2307-2319
    • (2003) Life Sci , vol.73 , pp. 2307-2319
    • Zhang, H.-N.1    Hea, J.-H.2    Yuanb, L.3    Lin, Z.-B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.