Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin-producing cells

Free Radical Biology and Medicine

Volumn 41, Issue 5, 2006, Pages 825-834

  Elsner, Matthias ^a   Gurgul Convey, Ewa ^a   Lenzen, Sigurd ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Alloxan; Catalase; Diabetes mellitus; Dialuric acid; Insulin producing cells; Reactive oxygen species; Superoxide dismutase

Indexed keywords

ALLOXAN; CATALASE; DIALURIC ACID; FREE RADICAL; GLUCOSE TRANSPORTER; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INSULIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ALLOXAN DIABETES MELLITUS; ANIMAL CELL; ARTICLE; AUTOOXIDATION; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ALLOXAN; ANIMALS; BARBITURATES; CATALASE; CELL SURVIVAL; DIABETES MELLITUS; DNA, COMPLEMENTARY; FREE RADICALS; INSULIN; ISLETS OF LANGERHANS; OXYGEN; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES;

ANIMALIA; RODENTIA;

EID: 33746766202     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.06.002     Document Type: Article

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