Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death

Cell Death and Differentiation

Volumn 18, Issue 6, 2011, Pages 996-1004

  Lai, S K ^a   Wong, C H ^a   Lee, Y P ^a   Li, H Y ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

caspase; condensin; mitotic cell death

Indexed keywords

CASPASE 3; CONDENSIN; CONDENSIN CAP H; DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL DEATH; CHROMOSOME LOSS; CONTROLLED STUDY; DNA FRAGMENTATION; HUMAN; HUMAN CELL; INTERPHASE; MITOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATASES; CASPASE 3; CELL DEATH; CHROMOSOMES, HUMAN; DNA FRAGMENTATION; DNA-BINDING PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MITOSIS; MULTIPROTEIN COMPLEXES;

EID: 79955860796     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.165     Document Type: Article

References (40)

1. Lowe SW, Lin AW. Apoptosis in cancer. Carcinogenesis 2000; 21: 485-495. (Pubitemid 30137934)
2. Brown JM, Attardi LD. The role of apoptosis in cancer development and treatment response. Nat Rev Cancer 2005; 5: 231-237. (Pubitemid 40314954)
3. Makin G, Hickman JA. Apoptosis and cancer chemotherapy. Cell Tissue Res 2000; 301: 143-152. (Pubitemid 30459861)
4. Portugal J, Bataller M, Mansilla S. Cell death pathways in response to antitumor therapy. Tumori 2009; 95: 409-421.
5. Roninson IB, Broude EV, Chang BD. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Updat 2001; 4: 303-313. (Pubitemid 34456384)
6. Mansilla S, Bataller M, Portugal J. Mitotic catastrophe as a consequence of chemotherapy. Anticancer Agents Med Chem 2006; 6: 589-602. (Pubitemid 44697117)
7. Okada H, Mak TW. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer 2004; 4: 592-603. (Pubitemid 39025054)
8. Schmidt M, Bastians H. Mitotic drug targets and the development of novel anti-mitotic anticancer drugs. Drug Resist Updat 2007; 10: 162-181. (Pubitemid 47449762)
9. Sudakin V, Yen TJ. Targeting mitosis for anti-cancer therapy. BioDrugs 2007; 21: 225-233. (Pubitemid 47104978)
10. Jackson JR, Patrick DR, Dar MM, Huang PS. Targeted anti-mitotic therapies: can we improve on tubulin agents? Nat Rev Cancer 2007; 7: 107-117. (Pubitemid 46160987)
11. Weaver BA, Cleveland DW. Decoding the links between mitosis, cancer, and chemotherapy: the mitotic checkpoint, adaptation, and cell death. Cancer Cell 2005; 8: 7-12. (Pubitemid 40991810)
12. Castedo M, Perfettini JL, Roumier T, Andreau K, Medema R, Kroemer G. Cell death by mitotic catastrophe: a molecular definition. Oncogene 2004; 23: 2825-2837. (Pubitemid 38638845)
13. Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008; 14: 111-122.
14. Gascoigne KE, Taylor SS. How do anti-mitotic drugs kill cancer cells? J Cell Sci 2009; 122: 2579-2585.
15. Holland AJ, Cleveland DW. Beyond genetics: surprising determinants of cell fate in antitumor drugs. Cancer Cell 2008; 14: 103-105.
16. Nunez G, Benedict MA, Hu Y, Inohara N. Caspases: the proteases of the apoptotic pathway. Oncogene 1998; 17: 3237-3245. (Pubitemid 29043976)
17. Mansilla S, Priebe W, Portugal J. Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms. Cell Cycle 2006; 5: 53-60.
18. Niikura Y, Dixit A, Scott R, Perkins G, Kitagawa K. BUB1 mediation of caspase-independent mitotic death determines cell fate. J Cell Biol 2007; 178: 283-296. (Pubitemid 47076464)
19. Kitagawa K, Niikura Y. Caspase-independent mitotic death (CIMD). Cell Cycle 2008; 7: 1001-1005. (Pubitemid 351679832)
20. Stevens JB, Liu G, Bremer SW, Ye KJ, Xu W, Xu J et al. Mitotic cell death by chromosome fragmentation. Cancer Res 2007; 67: 7686-7694. (Pubitemid 47281361)
21. Brito DA, Rieder CL. The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells. Cell Motil Cytoskeleton 2009; 66: 437-447.
22. Shi J, Orth JD, Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 2008; 68: 3269-3276.
23. Jordan MA, Kamath K. How do microtubule-targeted drugs work? An overview. Curr Cancer Drug Targets 2007; 7: 730-742.
24. Jordan MA, Wilson L. Microtubules as a target for anticancer drugs. Nat Rev Cancer 2004; 4: 253-265. (Pubitemid 38525281)
25. Rieder CL, Maiato H. Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev Cell 2004; 7: 637-651. (Pubitemid 39462685)
26. Ha GH, Kim HS, Lee CG, Park HY, Kim EJ, Shin HJ et al. Mitotic catastrophe is the predominant response to histone acetyltransferase depletion. Cell Death Differ 2009; 16: 483-497.
27. Dalton WB, Nandan MO, Moore RT, Yang VW. Human cancer cells commonly acquire DNA damage during mitotic arrest. Cancer Res 2007; 67: 11487-11492.
28. Quignon F, Rozier L, Lachages AM, Bieth A, Simili M, Debatisse M et al. Sustained mitotic block elicits DNA breaks: one-step alteration of ploidy and chromosome integrity in mammalian cells. Oncogene 2007; 26: 165-172. (Pubitemid 46095728)
29. Leslie M. Mitosis first, DNA repair later. J Cell Bio 2010; 190: 160.
30. Giunta S, Belotserkovskaya R, Jackson SP. DNA damage signaling in response to double-strand breaks during mitosis. J Cell Biol 190: 197-207.
31. Nagata S. Apoptotic DNA fragmentation. Exp Cell Res 2000; 256: 12-18. (Pubitemid 30211161)
32. Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 1998; 391: 96-99. (Pubitemid 28079223)
33. Hudson DF, Vagnarelli P, Gassmann R, Earnshaw WC. Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev Cell 2003; 5: 323-336. (Pubitemid 37006475)
34. Hirano T. Condensins: organizing and segregating the genome. Curr Biol 2005; 15: R265-R275.
35. Legagneux V, Cubizolles F, Watrin E. Multiple roles of condensins: a complex story. Biol Cell 2004; 96: 201-213. (Pubitemid 38461445)
36. Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene 2003; 22: 8543-8567. (Pubitemid 38028527)
37. Janicke RU. MCF-7 breast carcinoma cells do not express caspase-3. Breast Cancer Res Treat 2009; 117: 219-221.
38. Vogel C, Hager C, Bastians H. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation. Cancer Res 2007; 67: 339-345. (Pubitemid 46142793)
39. Toh WH, Nam SY, Sabapathy K. An essential role for p73 in regulating mitotic cell death. Cell Death Differ 2009; 17: 787-800.
40. Blank M, Lerenthal Y, Mittelman L, Shiloh Y. Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage. J Cell Biol 2006; 174: 195-206. (Pubitemid 44079855)