Decreased GABABreceptor function in the cerebellum and brain stem of hypoxic neonatal rats: Role of glucose, oxygen and epinephrine resuscitation

Journal of Biomedical Science

Volumn 18, Issue 1, 2011, Pages

  Anju, Thoppil R ^a   Jayanarayanan, Sadanandan ^a   Paulose, Cheramadatikudiyil S ^a  

^a Department of Physics   (India)

Author keywords

cerebellum and brain stem; GABAB; neonatal hypoxia

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID H 3; 4 AMINOBUTYRIC ACID RECEPTOR; ADRENALIN; BACLOFEN; GLUCOSE; GLUTAMATE DECARBOXYLASE; MESSENGER RNA; OXYGEN; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN HYPOXIA; BRAIN STEM; CEREBELLUM; CONTROLLED STUDY; GENE EXPRESSION; HYPOXIA; NEWBORN; NONHUMAN; OXYGEN THERAPY; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RESUSCITATION; TISSUE PREPARATION; ANIMAL; ANOXIA; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BRAIN STEM; CEREBELLUM; EPINEPHRINE; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; GLUCOSE; GLUTAMATE DECARBOXYLASE; HUMANS; OXYGEN; RATS; RATS, WISTAR; RECEPTORS, GABA-B; RESUSCITATION;

EID: 79955853799     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-18-31     Document Type: Article

References (75)

1. The association between preterm newborn hypotension and hypoxemia and outcome during the first year. JA Low AB Froese RS Galbraith JT Smith EE Sauerbrei EJ Derrick, Acta Paediatrica 1993 82 433 437 10.1111/j.1651-2227.1993. tb12717.x 7686060 (Pubitemid 23151472)
2. Mechanisms of perinatal cerebral injury in fetus and newborn. M Delivoria-Papadopoulos POM Mishra, Annals of the New York Academy of Sciences 2000 900 159 168 10818402 (Pubitemid 30251465)
3. Reactive species mechanisms of cellular hypoxicreoxygenation injury. C Li RM Jackson, American Journal of Physiology 2002 282 227 241
4. The role of free radicals in cerebral hypoxia and ischemia. J Rodrigo AP Fernandez J Serrano MA Peinado A Martinez, Free Radical Biology and Medicine 2005 39 26 50 10.1016/j.freeradbiomed.2005.02.010 15925277 (Pubitemid 40740221)
5. Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea. W Xu L Chi BW Row,, et al. Neuroscience 2004 126 313 323 10.1016/j.neuroscience.2004.03.055 15207349 (Pubitemid 38780807)
6. oxygen sensing need in CNS function: Physiological and pathological implications. T Acker H Acker, Journal of Experimental Biology 2004 207 3171 3188 10.1242/jeb.01075 15299039 (Pubitemid 39275292)
7. Excitation of phrenic and sympathetic output during acute hypoxia: Contribution of medullary oxygen detectors. IC Solomon, Respiration Physiology 2000 121 101 117 10.1016/S0034-5687(00)00122-5 10963768 (Pubitemid 30645511)
8. Modulation of respiration during brain hypoxia. JA Neubauer JE Melton NH Edelman, J Appl Physiol 1990 68 441 451 2180894 (Pubitemid 20088870)
9. Assessment of ventilatory response to hypoxia. JV Weil CW Zwillich, Chest 1976 70 1 124 128 10.1378/chest.70.1.124 939125
10. Reversible depressiozn of ventilation and cardiovascular function by ventriculocisternal perfusion with -aminobutyric acid in dogs. MP Kneussl P Pappagianopoulos B Hoop H Kazemi, Am Rev Respir Dis 1986 133 1024 1028 3717757 (Pubitemid 16090006)
11. Respiratory depressant effects of GABA - and -receptor agonists in the cat. AM Taveira da Silva B Hartley P Hamosh JA Quest RA Gillis, J Appl Physiol 1987 62 2264 2272 10.1063/1.339481 3038827
12. Glutamic acid and gamma-aminobutyric acid neurotransmitters in central control of breathing. H Kazemi B Hoop, J Appl Physiol 1991 70 1 7 10.1063/1.350309 1672687
13. Neurotransmitters and neuromodulators controlling the hypoxic respiratory response in anaesthetized cats. DW Richter P Schmidt-Garcon O Pierrefiche AM Bischoff PM Lalley, J Physiol 1999 514 567 578 10.1111/j.1469-7793.1999.567ae.x 9852336 (Pubitemid 29055982)
14. Serotonergic modulation of the respiratory rhythm generator at birth: an in vitro study in the rat. E Di Pasquale D Morin R Monteau G Hilaire, Neurosci Lett 1992 143 91 95 10.1016/0304-3940(92)90240-8 1436685
15. The role of adenosine in the respiratory and cardiovascular response to systemic hypoxia in the rat. M Neylon JM Marshall, J Physiol 1991 440 529 545 1804975
16. Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine. B Elnazir JM Marshall P Kumar, J Physiol 1996 492 573 585 9019551 (Pubitemid 26137764)
17. Brainstem activation of platelet-derived growth factor- receptor modulates the late phase of the hypoxic ventilatory response. D Gozal N Simakajornboon MA Czapla YD Xue E Gozal V Vlasic JA Lasky JY Liu, J Neurochem 2000 74 310 319 10617134 (Pubitemid 30012783)
18. Maturational changes in neuromodulation of central pathways underlying hypoxic ventilatory response. N Simakajornboon T Kuptanon, Respir Physiol Neurobiol 2005 149 273 286 10.1016/j.resp.2005.05.005 15950554 (Pubitemid 41406227)
19. Cerebrospinal fluid concentrations of glutamate and GABA during perinatal cerebral hypoxia-ischemia and seizures. O Cataltepe J Towfighi RC Vannucci, Brain Res 1996 709 326 330 10.1016/0006-8993(95)01437-3 8833771 (Pubitemid 26071277)
20. Extracellular overflow of glutamate, aspartate, GABA and taurine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia. H Hagberg P Andersson I Kjellmer K Thiringer M Thordstein, Neurosci Lett 1987 78 311 317 10.1016/0304-3940(87)90379-X 2888062 (Pubitemid 17106439)
21. Oxidative stress, hypoxia, and ischemia-like conditions increase the release of endogenous amino acids by distinct mechanisms in cultured retinal cells. AC Rego MS Santos CR Oliveira, J Neurochem 1996 66 2506 2516 8632176 (Pubitemid 26159088)
22. Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus. P Saransaari SS Oja, Int J Devl Neurosci 1997 15 2 163 174 10.1016/S0736-5748(97)80001-9 (Pubitemid 27212072)
23. Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. P Saransaari SS Oja, Neuochem Res 1998 23 563 570 10.1023/A:1022494921018 (Pubitemid 28177623)
24. B-receptor-mediated pre- and postsynaptic modulation of GABA and glycine transmission in respiratory rhythm-generating network in mouse. W Zhang A Barnbrock S Gajic A Pfeiffer B Ritter, The Journal of Physiology 2002 540 435 446 10.1113/jphysiol.2001.013225 11956334 (Pubitemid 35190122)
25. GABA(B) receptors in the nucleus tractus solitarii modulate the carotid chemoreceptor reflex in rats. M Suzuki M Tetsuka M Endo, Neurosci Lett 1999 260 21 24 10.1016/S0304-3940(98)00942-2 10027690 (Pubitemid 29066892)
26. GABAA and GABAB receptors differentially modulate volume and frequency in ventilatory compensation in obese Zucker rats. AL Yang MJ Lo H Ting JS Chen CY Huang SD Lee, J Appl Physiol 2007 102 350 357 16990497 (Pubitemid 46089785)
27. Neuroprotective effects hypoxia - ischemia in newborn piglets. S Schubert U Brandl M Brodhun C Ulrich J Spaltmann N Fiedler R Bauer, Brain Res 2005 1058 129 136 10.1016/j.brainres.2005.07.061 16139822 (Pubitemid 41416807)
28. Resuscitation of newborn infants with 100% oxygen or air: a systematic review and meta-analysis. PG Davis A Tan CPF O'Donnell A Schulze, Lancet 2004 364 1329 33 10.1016/S0140-6736(04)17189-4 15474135 (Pubitemid 39335824)
29. Air versus oxygen for resuscitation of infants at birth. A Tan A Schulze CPF O'Donnell PG Davis, The cochrane database of systemic reviews 2006 2005 2
30. Room air resuscitation versus oxygen resuscitation in the delivery room. KE Corff DL McCann, J Perinat Neonat Nurs 2005 19 379 90 (Pubitemid 41689634)
31. Reevaluating neonatal resuscitation with 100% oxygen. RJ Martin MC Walsh WA Carlo, Am J Respir Crit Care Med 2005 172 1360 10.1164/rccm.2509002 16301299
32. Regional studies of catecholamines in the rat brain: The disposition of [3H] Norepinephrine, [3H] DOPA in various regions of the brain. J Glowinski LL Iversen, J Neurochem 1966 13 655 669 10.1111/j.1471-4159.1966.tb09873.x 5950056
33. Effects of sodium and bicarbonate ions on gamma amino butyric acid receptor binding in synaptic membranes of rat brain. S Kurioka K Toshiaki M Makoto, J Neurochem 1981 37 418 421 10.1111/j.1471-4159.1981.tb00471.x 6267202 (Pubitemid 11059457)
34. Protein measurement with folin phenol reagent. OH Lowry NJ Rosebrough AL Farr J Randall, J Biol Chem 1951 193 265 275 14907713
35. The attractions of proteins for small molecules and ions. G Scatchard, Ann NY Acad Sci 1949 51 660 672 10.1111/j.1749-6632.1949.tb27297.x
36. Perinatal brain injury in the preterm and term newborn. AJ du Plessis JJ Volpe, Curr Opin Neurol 2002 15 151 7 10.1097/00019052-200204000-00005 11923628 (Pubitemid 34286899)
37. Multiorgan dysfunction in infants with post-asphyxial hypoxic - ischemic encephalopathy. P Shah S Riphagen J Beyene JM Perlman, Arch Dis Child Fetal Neonatal Ed 2004 89 152 5 10.1136/adc.2002.023093 14977901
38. Room-air resusciatation causes less damage to heart and kidney than 100% oxygen. M Vento J Sastre MA Asensi J Vina, Am J Respir Crit Care Med 2005 172 1393 8 10.1164/rccm.200412-1740OC 16141440 (Pubitemid 43069812)
39. Respiratory effects of N-methyl-D-aspartate on the ventrolateral medullary surface. J Mitra NR Prabhakar JL Overholt NS Cherniack, J Appl Physiol 1989 67 1814 1819 2574718 (Pubitemid 20039387)
40. Effect of N-methyl-D-aspartate-receptor blockage on hypoxic ventilatory response in unanesthetized piglets. J Lin C Suguihara J Huang D Hehre C Devia E Bancalari, J Appl Physiol 1996 80 1759 1763 8727564 (Pubitemid 26143927)
41. Nitric oxide modulates ventilatory responses to hypoxia in the developing rat. D Gozal E Gozal JE Torres YM Gozal TJ Nuckton PJ Hornby, Am J Respir Crit Care Med 1997 155 1755 1762 9154888 (Pubitemid 27216689)
42. Cardiorespiratory responses to systemic administration of a protein kinase C inhibitor in conscious rats. D Gozal GR Graff JE Torres SG Khicha GS Nayak N Simakajornboon E Gozal, J Appl Physiol 1998 84 641 648 10.1063/1.368090 9475876 (Pubitemid 28081119)
43. The role of inhibitory amino acids in control of respiratory motor output in an arterially perfused rat. F Hayashi J Lipski, Respir Physiol 1992 89 47 63 10.1016/0034-5687(92)90070-D 1325666
44. Effects of GABA receptor blockage on the respiratory response to hypoxia in sedated newborn piglets. J Huang C Suguihara D Hehre J Lin E Bancalari, J Appl Physiol 1994 77 1006 1010 8002484 (Pubitemid 24258341)
45. Central amino acid neurotransmitters and the hypoxic ventilatory response. I Soto-Arape MD Burton H Kazemi, Am J Respir Crit Care Med 1995 151 1113 1120 7697240
46. 4.. V Louzoun-Kaplan M Zuckerman J Regino Perez-Polo HM Golan, International Journal of Developmental Neuroscience 2008 26 77 85 10.1016/j.ijdevneu.2007.09.002 17936537 (Pubitemid 351192270)
47. Baclofen prevents hypoxia-induced consolidation impairment for passive avoidance in rats. H Car R Oksztel A Nadlewska K Wi, Pharmacological Research 2001 44 329 335 10.1006/phrs.2001.0868 11592869 (Pubitemid 32977926)
48. Breceptors and TASK-1. IM Fearon M Zhang C Vollmer CA Nurse, The Journal of Physiology 2003 553 83 94 10.1113/jphysiol. 2003.048298 12949228 (Pubitemid 37483917)
49. Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain. M Bergeron JM Gidday AY Yu GL Semenza DM Ferriero FR Sharp, Ann Neurol 2000 48 285 296 10.1002/1531-8249(200009)48:3<285::AID-ANA2 3.0.CO;2-8 10976634
50. Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain. M Bernaudin AS Nedelec D Divoux ET MacKenzie E Petit P Schumann-Bard, J Cereb Blood Flow Metab 2002 22 393 403 11919510 (Pubitemid 34273595)
51. Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. N Goda HE Ryan B Khadivi W McNulty RC Rickert RS Johnson, Mol Cell Biol 2003 23 359 369 10.1128/MCB.23.1.359-369.2003 12482987 (Pubitemid 36008526)
52. Hypoxia, HIF-1, and the pathophysiology of common human diseases. GL Semenza F Agani D Feldser N Iyer L Kotch E Laughner A Yu, Adv Exp Med Biol 2000 475 123 130 10849654 (Pubitemid 32197719)
53. HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia. MW Halterman HJ Federoff, Exp Neurol 1999 159 65 72 10.1006/exnr.1999.7160 10486175 (Pubitemid 29444903)
54. Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line. LR Aminova JC Chavez J Lee H Ryu A Kung JC Lamanna RR Ratan, J Biol Chem 2005 280 3996 4003 15557337 (Pubitemid 40223869)
55. The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes. G Vangeison D Carr HJ Federoff DA Rempe, J Neurosci 2008 28 1988 1993 10.1523/JNEUROSCI.5323-07.2008 18287515 (Pubitemid 351302661)
56. Posthypoxic glucose supplement reduces hypoxicischemic brain damage in the neonatal rat. H Hattori CG Wasterlain, Ann Neurol 2004 28 122 128
57. Hypoxia-ischemia in the immature brain. SJ Vannucci H Hagberg, J Exp Biol 2004 207 3749 3154 10.1242/jeb.01209 15371482
58. Breceptors activation in the NTS blocks the glycemic responses induced by carotid body receptor stimulation. Mánica Lemus S Montero JL Cadenas JJ Lara HR Tejeda-Chvez R Álvarez-Buylla Elena Roces de Álvarez-Buylla, Autonomic Neuroscience 2008 141 73 82 10.1016/j.autneu.2008.05.009 18599364
59. Comparison of 30 and the 100% inspired oxygen concentrations during early post-resuscitation period: a randomised controlled pilot study. M Kuisma J Boyd V Voipio A Alaspaa RO Roine P Rosenberg, Resuscitation 2006 69 199 206 10.1016/j.resuscitation.2005.08.010 16500018
60. Persistent neurochemical changes in neonatal piglets after hypoxia-ischemia and resuscitation with 100%, 21% or 18% oxygen. LJ Lauren C Po-Yin L Obaid M Emara ST Johnson DL Bigam KG Todd, Resuscitation 2008 77 111 120 10.1016/j.resuscitation.2007.10.008 18083289
61. Reactive oxygen species: Oxidative damage and pathogenesis. U Bandyopadhyay D Das K Ranajit V Banerjee, Current Science 1999 77 658 666 (Pubitemid 129558409)
62. Superoxide dismutase functional regulation in neonatal hypoxia: Effect of glucose, oxygen and epinephrine. TR Anju B Athira CS Paulose, Indian J Biochem Biophys 2009 46 166 171 19517994
63. After hypoxia and glucose depletion causes reactive oxygen species production by mitochondria in HUVEC. TS Matharan E Laemmel J Duranteau E Vicaut, American Journal of Physiology: Regulatory Integrative and Comparative Physiology 2004 287 1037 R1043 10.1152/ajpregu.00048.2004 (Pubitemid 39391047)
64. Impaired early neurologic outcome in newborn piglets reoxygenated with 100% oxygen compared with room air after pneumothorax-induced asphyxia. P Temesvari E Karg I Bádi I Németh S Pintér K Lazics, Pediatric Research 2001 49 812 819 10.1203/00006450-200106000-00017 11385143 (Pubitemid 32522059)
65. 2increases cerebral injury in hypoxemic piglets. BH Munkeby WB Borke K Bjornland LL Sikkeland GL Borge B Halvorsen OD Saugstad, Pediatric Research 2004 56 5 783 790 10.1203/01.PDR. 0000141988.89820.E3 15347772 (Pubitemid 39403406)
66. Hyperoxia with 100% oxygen following hypoxia-ischemia increases brain damage in newborn rats. R Shimabuku A Ota S Pereyra B Veliz E Paz G Nakachi, Biology of Neonate 2005 88 168 171 10.1159/000086206 (Pubitemid 41433547)
67. Acetylcholine esterase activity and behavioral response in hypoxia induced neonatal rats: Effect of glucose, oxygen and epinephrine supplementation. F Chathu A Krishnakumar CS Paulose, Brain and cognition 2008 68 59 66 10.1016/j.bandc.2008.02.124 18406032
68. 2Areceptor function under hypoxia in neonatal rats: Role of glucose, oxygen, and epinephrine resuscitation. TR Anju M Jobin S Jayanarayanan CS Paulose, Respir Physiol Neurobiol 2010 172 3 147 153 10.1016/j.resp.2010.05.009 20471502
69. Dopamine D (1) and D(2) receptor functional down regulation in the cerebellum of hypoxic neonatal rats: Neuroprotective role of glucose and oxygen, epinephrine resuscitation. J Binoy MS Nandhu CS Paulose, Pharmacological Research 2009
70. Does sustained epinephrine release trigger a hypoxia-neovascularization cascade? E Karacaoglu I Bayram B Celiköz RJ Zienowicz, Plast Reconstr Surg 2007 119 858 64 10.1097/01.prs.0000252004.78314.56 17312488
71. Long-term impairment in the neurochemical activity of the sympathoadrenal system after neonatal hypoxia in the rat. V Soulier J Peyronnet JM Pequignot JM Cottet-Emard H Lagercrantz Y Dalmaz, Pediatr Res 1997 42 30 38 10.1203/00006450-199707000-00006 9212034 (Pubitemid 27276755)
72. Brain imaging studies of the anatomical and functional consequences of preterm birth for human brain development. BS Peterson, Ann NY Acad Sci 2003 1008 219 237 10.1196/annals.1301.023 14998887 (Pubitemid 38265165)
73. Neonatal risk factors and later neurodevelopmental disturbances. E Lindahl K Michelsson M Helenius M Parre, Dev Med Child Neurol 1988 30 571 589 2465930
74. Childhood neurological morbidity and its association with gestational age, intrauterine growth retardation and perinatal stress. AT Berg, Paediatr Perinat Epidemiol 1988 2 229 238 10.1111/j.1365-3016.1988.tb00213.x 2467264
75. Sub-neurotoxic neonatal anoxia induces subtle behavioural changes and specific abnormalities in brain group-I metabotropic glutamate receptors in rats. P Casolini AR Zuena C Cinque, J Neurochem 2005 95 137 145 10.1111/j.1471-4159.2005.03349.x 16181418 (Pubitemid 41384432)