CD46 protects against chronic obstructive pulmonary disease

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Grumelli, Sandra ^a,b   Lu, Bao ^d   Peterson, Leif ^c   Maeno, Toshitaka ^a   Gerard, Craig ^d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSIDAD CATÓLICA DE CÓRDOBA   (Argentina)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C5A; ELASTIN; FAS ANTIGEN; IMMUNOGLOBULIN G; INTERLEUKIN 12; MEMBRANE COFACTOR PROTEIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN FUNCTION; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL DEATH; CELL PROLIFERATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPLEMENT SYSTEM; CONTROLLED STUDY; DISEASE RESISTANCE; DISEASE SEVERITY; EMPHYSEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE FUNCTION; HUMAN; HUMAN TISSUE; IMMUNOREGULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRECIPITATION; PROTEIN DEGRADATION; PROTEIN DEPLETION; QUANTITATIVE ANALYSIS; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOKING HABIT; ANIMAL; DNA MICROARRAY; DRUG EFFECT; FEMALE; GENETICS; IMMUNOHISTOCHEMISTRY; LUNG; MALE; METABOLISM; MIDDLE AGED; SIGNAL TRANSDUCTION; SMOKING;

MURINAE;

AGED; ANIMALS; ANTIGENS, CD46; ANTIGENS, CD95; COMPLEMENT C3B; ELASTIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG; MALE; MICE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL TRANSDUCTION; SMOKING; T-LYMPHOCYTES, REGULATORY;

EID: 79955843762     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018785     Document Type: Article

References (49)

1. Anthonisen NR, Connett JE, Murray RP, (2002) Smoking and lung function of Lung Health Study participants after 11 years. Am J Respir Crit Care Med 166 (5): 675-9.
2. Shapiro SD, (1999) The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160 (5 Pt 2): S29-32 Review.
3. Cosio MG, Guerassimov A, (1999) Chronic obstructive pulmonary disease. Inflammation of small airways and lung parenchyma. Am J Respir Crit Care Med 160 (5 Pt 2): S21-5.
4. Saetta M, Mariani M, Panina-Bordignon P, Turato G, Buonsanti C, et al. (2002) Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 15;165 (10): 1404-9.
5. Grumelli S, Corry DB, Song LZ, Song L, Green L, (2004) An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 1 (1): e8. Epub 2004 Oct 19.
6. Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, et al. (2007) Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med 13 (5): 567-9. Epub 2007 Apr 22.
7. Greene C, Low TB, O'Neill SJ, McElvaney NG, (2010) Anti-proline-glycine-proline or antielastin autoantibodies are not evident in chronic Inflammatory Lung Disease. Am J Respir Crit Care Med Vol 181: 31-35.
8. Wood AM, Harrison RM, Semple S, Ayres JG, Stockley RA, (2010) Outdoor air pollution is associated with rapid decline of lung function in alpha-1-antitrypsin deficiency. Occup Environ Med 67 (8): 556-61.
9. Cottin V, Fabien N, Khouatra C, Moreira A, Cordier JF, (2009) Anti-elastin autoantibodies are not present in combined pulmonary fibrosis and emphysema. Eur Respir J 33: 219-221.
10. Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, et al. (2010) Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. 138 (5): 1140-1147.
11. Di Stefano A, Caramori G, Gnemmi I, Contoli M, Vicari C, et al. (2009) T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol 157 (2): 316-24.
12. De Sanctis JB, Garmendia JV, Moreno D, Larocca N, Mijares M, et al. (2009) Pharmacological modulation of Th17. Recent Pat Inflamm Allergy Drug Discov 3 (2): 149-56.
13. Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, et al. (2010) Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 138 (5): 1140-7.
14. Lane N, Robins RA, Corne J, Fairclough L, (2010) Regulation in chronic obstructive pulmonary disease: the role of regulatory T-cells and Th17 cells. Clin Sci (Lond) 119 (2): 75-86.
15. Alcorn JF, Crowe CR, Kolls JK, (2010) TH17 cells in asthma and COPD. Annu Rev Physiol 17; 72: 495-516.
16. Nagata S, (1997) Apoptosis by death factor. Cell 88: 355-365.
17. Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG, (2005) Cellular and genetic mechanisms of self-tolerance and autoimmunity. Nature 435 (7042): 590-7 Review.
18. Jani TS, Gobejishvili L, Hote PT, Barve AS, Joshi-Barve S, et al. (2008) Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells. Cell Res doi:10.1038/cr.2008.314.
19. Kemper C, Chan AC, Green JM, Brett KA, Murphy KM, et al. (2003) Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421 (6921): 388-92.
20. Richards A, Kemp EJ, Liszewski MK, Goodship JA, Lampe AK, et al. (2003) Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. Proc Natl Acad Sci U S A 100 (22): 12966-71.
21. Devaux P, Christiansen D, Fontaine M, Gerlier D, (1999) Control of C3b and C5b deposition by CD46 (membrane cofactor protein) after alternative but not classical complement activation. Eur J Immunol 29 (3): 815-22.
22. Inoue T, Shimoda N, Horikawa Y, Tachiki Y, Satoh S, et al. (2001) A case of retroperitoneal fibrosis responding to steroid therapy. Hinyokika Kiyo 47 (5): 321-4.
23. Madani A, Keyzer C, Gevenois PA, (2001) Quantitative computed tomography assessment of lung structure and function in pulmonary emphysema. Eur Respir J 18 (4): 720-30 Review.
24. Uppaluri R, Mitsa T, Sonka M, Hoffman EA, McLennan G, (1997) Quantification of pulmonary emphysema from lung computed tomography images. Am J Respir Crit Care Med 156 (1): 248.
25. Pauwels R, (2001) Global initiative for chronic obstructive lung diseases (GOLD): time to act. Eur Respir J 18 (6): 901-2.
26. Lockhart DJ, Dong H, Byrne MC, Follettie MT, Gallo MV, (1996) Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol 14 (13): 1675-80.
27. Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD, (1997) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 26; 277 (5334): 2002-4.
28. Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, et al. (2007) CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol 15;178 (12): 8090.
29. Xu J, Tian J, Grumelli S, Haley KJ, Shapiro SD, (2006) Stage-specific effects of cAMP signaling during distal lung epithelial development. J Biol Chem 15;281 (50): 38894-904. Epub 2006 Oct 3.
30. Grosso LE, Scott M, (1993) PGAIPG, a repeated hexapeptide of bovine and human tropoelastin, is chemotactic for neutrophils and Lewis lung carcinoma cells. Arch Biochem Biophys 305 (2): 401-4.
31. Sprent J, Kishimoto H, (2002) The thymus and negative selection. Immunol Rev 185: 126-35.
32. Rochat-Steiner V, Becker K, Micheau O, Schneider P, Burns K, et al. (2000) FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation. J Exp Med 16;192 (8): 1165-74.
33. Fernández-Salas E, Suh KS, Speransky VV, Bowers WL, Levy JM, et al. (2002) mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol 22 (11): 3610-20.
34. Katsanou V, Papadaki O, Milatos S, Blackshear PJ, Anderson P, et al. (2005) HuR as a negative posttranscriptional modulator in inflammation. Molec Cell 19: 777-789.
35. Zou C, Ma J, Wang X, Guo L, Zhu Z, et al. (2007) Lack of Fas antagonism by Met in human fatty liver disease. Nature Med 13: 1078-1085.
36. Lai KC, Chang KW, Liu CJ, Kao SY, Lee TC, (2008) IFN-induced protein with tetratricopeptide repeats 2 inhibits migration activity and increases survival of oral squamous cell carcinoma. Mol Cancer Res 6 (9): 1431-9.
37. Yamamot K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, (1994) Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 14: 4342-4349.
38. Gianni M, Terao M, Fortino I, LiCalzi M, Viggiano V, et al. (1997) Stat1 is induced and activated by all-trans retinoic acid in acute promyelocytic leukemia cells. Blood 89: 1001-1012.
39. Matikainen S, Ronni T, Hurme M, Pine R, Julkunen I, (1996) Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells. Blood 88 (1): 114-23.
40. Shaulian E, Karin M, (2002) AP-1 as a regulator of cell life and death. Nat Cell Biol 4 (5): E131-6 Review.
41. Curtis JL, Freeman CM, Hogg JC, (2007) The immunopathogenesis of chronic obstructive pulmonary disease insights from recent research. Proc Am Thorac Soc Vol 4: 512-521,.DO10.1513/pats.200701-002FM.
42. He J, Gurunathan S, Iwasaki A, Ash-Shaheed B, Kelsall BL, (2000) Primary role for Gi protein signaling in the regulation of interleukin 12 productions and the induction of T helper cell type 1 response. J Exp Med 191 (9): 1605-10.
43. Skokowa J, Ali SR, Felda O, Kumar V, Konrad S, et al. (2005) Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation. J Immunol 174: 3041-50.
44. Huber-Lang M, Younkin EM, Sarma JV, Riedemann N, McGuire SR, et al. (2002) Generation of C5a by phagocytic cells. Am J Pathol 161 (5): 1849-59.
45. Cai X, Castleman WL, (2002) Increased IFN-gamma protein in bronchoalveolar lavage fluid of anti-IP-10 antibody-treated F344 rats following Sendai viral infection. J Interferon Cytokine Res 22 (12): 1175-9.
46. Cai X, Castleman WL, (2003) Early high expression of IP-10 in F344 rats resistant to Sendai virus-induced airway injury. Am J Physiol Lung Cell Mol Physiol, 285 (6): L1263-9.
47. Wang Z, Zhen T, Zhu Z, Homer RJ, Chapman HA Jr, et al. (2000) Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med 192 (11): 1587-600.
48. Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy KM, et al. (2005) Interleukin 17- producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6: 1123-32.
49. Park H, Li Z, Yang XO, Chang SH, Nurieva R, et al. (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6: 1133-41.