Outdoor air pollution is associated with rapid decline of lung function in α-1-antitrypsin deficiency

Occupational and Environmental Medicine

Volumn 67, Issue 8, 2010, Pages 556-561

  Wood, Alice M ^a   Harrison, Roy M ^a   Semple, Sean ^a   Ayres, Jon G ^a   Stockley, Robert A ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; NITROGEN DIOXIDE; OZONE; SULFUR DIOXIDE;

ADULT; AIR POLLUTION; ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; FEMALE; FORCED EXPIRATORY VOLUME; GENOTYPE; HUMAN; LUNG FUNCTION; MALE; PRIORITY JOURNAL;

AIR POLLUTION; ALPHA 1-ANTITRYPSIN DEFICIENCY; FEMALE; FORCED EXPIRATORY VOLUME; GREAT BRITAIN; HUMANS; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; OZONE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; QUESTIONNAIRES; RESPIRATORY FUNCTION TESTS; SULFUR DIOXIDE;

EID: 77955606635     PISSN: 13510711     EISSN: 14707926     Source Type: Journal    
DOI: 10.1136/oem.2009.047589     Document Type: Article

References (35)

1. Dockery DW, Pope CA 3rd, Xu X, et al. An association between air pollution and mortality in six U.S. cities. N Engl J Med 1993;329:1753-9.
2. Pope CA 3rd, Burnett RT, Thun MJ, et al. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 2002;287:1132-41.
3. Schwartz J. Short term fluctuations in air pollution and hospital admissions of the elderly for respiratory disease. Thorax 1995;50:531-8.
4. Atkinson RW, Anderson HR, Sunyer J, et al. Acute effects of particulate air pollution on respiratory admissions: results from APHEA 2 project. Air Pollution and Health: a European Approach. Am J Respir Crit Care Med 2001;164:1860-6.
5. Schouten JP, Vonk JM, de Graaf A. Short term effects of air pollution on emergency hospital admissions for respiratory disease: results of the APHEA project in two major cities in The Netherlands, 1977-89. J Epidemiology Community Health 1996;50(Suppl 1):s22-9.
6. Bell ML, Dominici F, Samet JM. A meta-analysis of time-series studies of ozone and mortality with comparison to the national morbidity, mortality, and air pollution study. Epidemiology 2005;16:436-45.
7. Sunyer J, Spix C, Quenel P, et al. Urban air pollution and emergency admissions for asthma in four European cities: the APHEA Project. Thorax 1997;52:760-5.
8. Needham M, Stockley RA. Alpha 1-antitrypsin deficiency. 3: clinical manifestations and natural history. Thorax 2004;59:441-5.
9. Stockley RA, Luisetti M. Alpha-1-antirypsin deficiency: the biochemical basis of pulmonary emphysema. Pavia: IRCCS, 1999.
10. Li XY, Gilmour PS, Donaldson K, et al. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 1996;51:1216-22.
11. Wood AM, Harrison RM, Semple S, et al. Outdoor air pollution is associated with disease severity in alpha-1-antitrypsin deficiency. Eur Respir J 2009;34:346-53.
12. Piitulainen E, Tornling G, Eriksson S. Environmental correlates of impaired lung function in non-smokers with severe alpha 1-antitrypsin deficiency (PiZZ). Thorax 1998;53:939-43.
13. Senn O, Russi EW, Imboden M, et al. alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants. Eur Respir J 2005;26:909-17.
14. Seersholm N, Kok-Jensen A, Dirksen A. Decline in FEV1 among patients with severe hereditary alpha 1-antitrypsin deficiency type PiZ. Am J Respir Crit Care Med 1995;152:1922-5.
15. Celli BR, Thomas NE, Anderson JA, et al. Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study. Am J Respir Crit Care Med 2008;178:332-8.
16. Donaldson GC, Seemungal TA, Bhowmik A, et al. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002;57:847-52.
17. Anon. Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin The Alpha-1-Antitrypsin Deficiency Registry Study Group. Am J Respir Crit Care Med 1998;158:49-59.
18. Dowson LJ, Guest PJ, Hill SL, et al. High-resolution computed tomography scanning in alpha1-antitrypsin deficiency: relationship to lung function and health status. Eur Respir J 2001;17:1097-104.
19. Anthonisen NR, Manfreda J, Warren CP, et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med 1987;106:196-204.
20. ONS. National statistics postcode directory 2006. http://www.statistics. gov.uk/geography/nspd.asp (accessed 2007).
21. Semple SE, Dick F, Cherrie JW. Exposure assessment for a population-based case-control study combining a job-exposure matrix with interview data. Scand J Work Environ Health 2004;30:241-8.
22. Franceschi C, Bezrukov V, Blanche H, et al. Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging). Ann N Y Acad Sci 2007;1100:21-45.
23. Health and Safety Executive. List of approved workplace exposure limits 2007. http://www.hse.gov.uk/coshh/table1.pdf.
24. Stedman JR, Kent AJ. An analysis of the spatial patterns of human health related ozone metrics across the UK in 1995, 2003 and 2005. Atmos Environ 2008;42:1702-16.
25. Kent AJ, Grice S, Stedman JR, et al. Report to DEFRA: UK Air Quality modelling for annual reporting 2005 on ambient air quality assessment under Council Directives 96/62/EC, 1999/30/EC and 2000/69/EC AEA Energy and Environment 2005. ED48208.
26. Dirksen A, Piitulainen E, Parr DG, et al. Exploring the role of CT densitometry: a randomised study of augmentation therapy in alpha1-antitrypsin deficiency. Eur Respir J 2009;33:1345-53.
27. Enright PL, Connett JE, Kanner RE, et al. Spirometry in the Lung Health Study: II. Determinants of short-term intraindividual variability. Am J Respir Crit Care Med 1995;151:406-11.
28. American Thoracic Society, European Respiratory Society Statement. American Thoracic Society/European Respiratory Society Statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med 2003;168:818-900.
29. Nadziejko C, Finkelstein I, Balmes JR. Contribution of secretory leukocyte proteinase inhibitor to the antiprotease defense system of the peripheral lung: effect of ozone-induced acute inflammation. Am J Respir Crit Care Med 1995;152:1592-8.
30. Dawkins PA, Dawkins CL, Wood AM, et al. Rate of progression of lung function impairment in alpha1-antitrypsin deficiency. Eur Respir J 2009;33:1338-44.
31. Downs SH, Schindler C, Liu LJ, et al. Reduced exposure to PM10 and attenuated age-related decline in lung function. N Engl J Med 2007;357:2338-47.
32. Pope CA 3rd, Kanner RE. Acute effects of PM10 pollution on pulmonary function of smokers with mild to moderate chronic obstructive pulmonary disease. Am Rev Respir Dis 1993:147:1336-40.
33. Schwartz J. Air pollution and hospital admissions for the elderly in Detroit, Michigan. Am J Respir Crit Care Med 1994;150:648-55.
34. Camp PG, O'Donnell DE, Postma DS. Chronic obstructive pulmonary disease in men and women: myths and reality. Proc Am Thorac Soc 2009;6:535-8.
35. Martinez FJ, Curtis JL, Sciurba F, et al. Sex differences in severe pulmonary emphysema. Am J Respir Crit Care Med 2007;176:243-52.