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Volumn 7, Issue 2, 2011, Pages 107-112

Quantitative molecular imaging of neuronal nicotinic acetylcholine receptors in the human brain with a-85380 radiotracers

Author keywords

2FA; 5IA; A 85380; Human brain imaging; Nicotinic acetylcholine receptors; Positron emission tomography; Single photon emission computed tomography; Tobacco dependence; Varenicline

Indexed keywords

3 (2 AZETIDINYLMETHOXY)PYRIDINE; EPIBATIDINE; FLUORINE 18; IODINE 123; NICOTINIC RECEPTOR; RADIOLIGAND; TRACER;

EID: 79955654102     PISSN: 15734056     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340511795445676     Document Type: Article
Times cited : (10)

References (83)
  • 1
    • 23944523547 scopus 로고    scopus 로고
    • The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes
    • Naqvi NH, Bechara A. The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes. Pharmacol Biochem Behav 2005; 81(4): 821-9.
    • (2005) Pharmacol Biochem Behav , vol.81 , Issue.4 , pp. 821-829
    • Naqvi, N.H.1    Bechara, A.2
  • 2
    • 0032759393 scopus 로고    scopus 로고
    • Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in he central nervous system
    • Vizi ES, Lendvai B. Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in he central nervous system. Brain Res Brain Res Rev 1999; 30(3): 219-35.
    • (1999) Brain Res Brain Res Rev , vol.30 , Issue.3 , pp. 219-235
    • Vizi, E.S.1    Lendvai, B.2
  • 3
    • 0033960085 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors as novel drug targets
    • Lloyd GK, Williams M. Neuronal nicotinic acetylcholine receptors as novel drug targets. J Pharmacol Exp Ther 2000; 292(2): 461-7.
    • (2000) J Pharmacol Exp Ther , vol.292 , Issue.2 , pp. 461-467
    • Lloyd, G.K.1    Williams, M.2
  • 4
    • 0030175612 scopus 로고    scopus 로고
    • Nicotinic receptors in the development and modulation of CNS synapses
    • Role LW, Berg DK. Nicotinic receptors in the development and modulation of CNS synapses. Neuron 1996; 16(6): 1077-85.
    • (1996) Neuron , vol.16 , Issue.6 , pp. 1077-1085
    • Role, L.W.1    Berg, D.K.2
  • 5
    • 0023751963 scopus 로고
    • Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies
    • Whiting PJ, Lindstrom JM. Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies. J Neurosci 1988; 8(9): 3395-404.
    • (1988) J Neurosci , vol.8 , Issue.9 , pp. 3395-3404
    • Whiting, P.J.1    Lindstrom, J.M.2
  • 6
    • 0035726679 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor subunit knockout mice: Physiological and behavioral phenotypes and possible clinical implications
    • Picciotto MR, Caldarone BJ, Brunzell DH, Zachariou V, Stevens TR, King SL. Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Pharmacol Ther 2001; 92(2-3): 89-108.
    • (2001) Pharmacol Ther , vol.92 , Issue.2-3 , pp. 89-108
    • Picciotto, M.R.1    Caldarone, B.J.2    Brunzell, D.H.3    Zachariou, V.4    Stevens, T.R.5    King, S.L.6
  • 7
    • 33846314737 scopus 로고    scopus 로고
    • Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons
    • Azam L, Chen Y, Leslie FM. Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons. Neuroscience 2007; 144(4): 1347-60.
    • (2007) Neuroscience , vol.144 , Issue.4 , pp. 1347-1360
    • Azam, L.1    Chen, Y.2    Leslie, F.M.3
  • 8
    • 0029943635 scopus 로고    scopus 로고
    • Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs
    • Pontieri FE, Tanda G, Orzi F, Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 1996; 382(6588): 255-7.
    • (1996) Nature , vol.382 , Issue.6588 , pp. 255-257
    • Pontieri, F.E.1    Tanda, G.2    Orzi, F.3    Di Chiara, G.4
  • 9
    • 0032504566 scopus 로고    scopus 로고
    • Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (+/-)-[3H]epibatidine
    • Marutle A, Warpman U, Bogdanovic N, Nordberg A. Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (+/-)-[3H]epibatidine. Brain Res 1998; 801(1-2): 143-9.
    • (1998) Brain Res , vol.801 , Issue.1-2 , pp. 143-149
    • Marutle, A.1    Warpman, U.2    Bogdanovic, N.3    Nordberg, A.4
  • 10
    • 0344588832 scopus 로고    scopus 로고
    • Regional distribution of nicotinic receptors during prenatal development of human brain and spinal cord
    • Hellstrom-Lindahl E, Gorbounova O, Seiger A, Mousavi M, Nordberg A. Regional distribution of nicotinic receptors during prenatal development of human brain and spinal cord. Brain Res Dev Brain Res 1998; 108(1-2): 147-60.
    • (1998) Brain Res Dev Brain Res , vol.108 , Issue.1-2 , pp. 147-160
    • Hellstrom-Lindahl, E.1    Gorbounova, O.2    Seiger, A.3    Mousavi, M.4    Nordberg, A.5
  • 11
    • 58149385076 scopus 로고    scopus 로고
    • Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration
    • Pons S, Fattore L, Cossu G, et al. Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. J Neurosci 2008; 28(47): 12318-27.
    • (2008) J Neurosci , vol.28 , Issue.47 , pp. 12318-12327
    • Pons, S.1    Fattore, L.2    Cossu, G.3
  • 12
    • 17144413330 scopus 로고
    • Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
    • Picciotto MR, Zoli M, Lena C, et al. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 1995; 374(6517): 65-7.
    • (1995) Nature , vol.374 , Issue.6517 , pp. 65-67
    • Picciotto, M.R.1    Zoli, M.2    Lena, C.3
  • 13
    • 0034280436 scopus 로고    scopus 로고
    • Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse
    • Ross SA, Wong JY, Clifford JJ, et al. Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse. J Neurosci. 2000; 20(17): 6431-41.
    • (2000) J Neurosci , vol.20 , Issue.17 , pp. 6431-6441
    • Ross, S.A.1    Wong, J.Y.2    Clifford, J.J.3
  • 14
    • 36849058086 scopus 로고    scopus 로고
    • Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
    • Mineur YS, Picciotto MR. Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction. Biochem Pharmacol 2008; 75(1): 323-33.
    • (2008) Biochem Pharmacol , vol.75 , Issue.1 , pp. 323-333
    • Mineur, Y.S.1    Picciotto, M.R.2
  • 15
    • 77954473188 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor alpha5 subunit plays a key role in attention circuitry and accuracy
    • Bailey CD, De Biasi M, Fletcher PJ, Lambe EK. The nicotinic acetylcholine receptor alpha5 subunit plays a key role in attention circuitry and accuracy. J Neurosci 2010; 30(27): 9241-52.
    • (2010) J Neurosci , vol.30 , Issue.27 , pp. 9241-9252
    • Bailey, C.D.1    de Biasi, M.2    Fletcher, P.J.3    Lambe, E.K.4
  • 16
    • 21844438972 scopus 로고    scopus 로고
    • Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
    • Maskos U, Molles BE, Pons S, et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature 2005; 436(7047): 103-7.
    • (2005) Nature , vol.436 , Issue.7047 , pp. 103-107
    • Maskos, U.1    Molles, B.E.2    Pons, S.3
  • 17
    • 0343517069 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors during prenatal development and brain pathology in human aging
    • Hellstrom-Lindahl E, Court JA. Nicotinic acetylcholine receptors during prenatal development and brain pathology in human aging. Behav Brain Res 2000; 113(1-2): 159-68.
    • (2000) Behav Brain Res , vol.113 , Issue.1-2 , pp. 159-168
    • Hellstrom-Lindahl, E.1    Court, J.A.2
  • 18
    • 78650132438 scopus 로고    scopus 로고
    • Short-term effect of combined drug therapy and cognitive stimulation therapy on the cognitive function of Alzheimer's disease
    • Matsuda O, Shido E, Hashikai A, et al. Short-term effect of combined drug therapy and cognitive stimulation therapy on the cognitive function of Alzheimer's disease. Psychogeriatrics 2010; 10(4): 167-72.
    • (2010) Psychogeriatrics , vol.10 , Issue.4 , pp. 167-172
    • Matsuda, O.1    Shido, E.2    Hashikai, A.3
  • 19
    • 0028360980 scopus 로고
    • PET studies of the uptake of (S)- and (R)-[11C]nicotine in the human brain: Difficulties in visualizing specific receptor binding in vivo
    • Nyback H, Halldin C, Ahlin A, Curvall M, Eriksson L. PET studies of the uptake of (S)- and (R)-[11C]nicotine in the human brain: difficulties in visualizing specific receptor binding in vivo. Psychopharmacology (Berl) 1994; 115(1-2): 31-6.
    • (1994) Psychopharmacology (Berl) , vol.115 , Issue.1-2 , pp. 31-36
    • Nyback, H.1    Halldin, C.2    Ahlin, A.3    Curvall, M.4    Eriksson, L.5
  • 20
    • 0032438052 scopus 로고    scopus 로고
    • PET quantification of specific binding of carbon-11-nicotine in human brain
    • Muzic RF, Jr., Berridge MS, Friedland RP, Zhu N, Nelson AD. PET quantification of specific binding of carbon-11-nicotine in human brain. J Nucl Med 1998; 39(12): 2048-54.
    • (1998) J Nucl Med , vol.39 , Issue.12 , pp. 2048-2054
    • Muzic Jr., R.F.1    Berridge, M.S.2    Friedland, R.P.3    Zhu, N.4    Nelson, A.D.5
  • 21
    • 0024400034 scopus 로고
    • In vivo specific binding of [3H]1-nicotine in the mouse brain
    • Broussolle EP, Wong DF, Fanelli RJ, London ED. In vivo specific binding of [3H]1-nicotine in the mouse brain. Life Sci 1989; 44(16): 1123-32.
    • (1989) Life Sci , vol.44 , Issue.16 , pp. 1123-1132
    • Broussolle, E.P.1    Wong, D.F.2    Fanelli, R.J.3    London, E.D.4
  • 22
    • 0031002184 scopus 로고    scopus 로고
    • An attempt to visualize baboon brain nicotinic receptors with N-[11C]ABT-418 and N-[11C]methyl-cytisine
    • Valette H, Bottlaender M, Dolle F, Dolci L, Syrota A, Crouzel C. An attempt to visualize baboon brain nicotinic receptors with N-[11C]ABT-418 and N-[11C]methyl-cytisine. Nucl Med Commun 1997; 18(2): 164-8.
    • (1997) Nucl Med Commun , vol.18 , Issue.2 , pp. 164-168
    • Valette, H.1    Bottlaender, M.2    Dolle, F.3    Dolci, L.4    Syrota, A.5    Crouzel, C.6
  • 23
    • 0028037690 scopus 로고
    • Epibatidine, an alkaloid from the poison frog Epipedobates tricolor, is a powerful ganglionic depolarizing agent
    • Fisher M, Huangfu D, Shen TY, Guyenet PG. Epibatidine, an alkaloid from the poison frog Epipedobates tricolor, is a powerful ganglionic depolarizing agent. J Pharmacol Exp Ther 1994; 270(2): 702-7.
    • (1994) J Pharmacol Exp Ther , vol.270 , Issue.2 , pp. 702-707
    • Fisher, M.1    Huangfu, D.2    Shen, T.Y.3    Guyenet, P.G.4
  • 24
    • 0030724888 scopus 로고    scopus 로고
    • Fluoro-norchloroepibatidine: Preclinical assessment of acute toxicity
    • Molina PE, Ding YS, Carroll FI, et al. Fluoro-norchloroepibatidine: preclinical assessment of acute toxicity. Nucl Med Biol 1997; 24(8): 743-7.
    • (1997) Nucl Med Biol , vol.24 , Issue.8 , pp. 743-747
    • Molina, P.E.1    Ding, Y.S.2    Carroll, F.I.3
  • 25
    • 13344282051 scopus 로고    scopus 로고
    • Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors
    • Abreo MA, Lin NH, Garvey DS, et al. Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors. J Med Chem 1996; 39(4): 817-25.
    • (1996) J Med Chem , vol.39 , Issue.4 , pp. 817-825
    • Abreo, M.A.1    Lin, N.H.2    Garvey, D.S.3
  • 26
    • 0032505152 scopus 로고    scopus 로고
    • 2-, 5-, and 6-Halo-3- (2(S)-azetidinylmethoxy)pyridines: Synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling
    • Koren AO, Horti AG, Mukhin AG, et al. 2-, 5-, and 6-Halo-3- (2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling. J Med Chem 1998; 41(19): 3690-8.
    • (1998) J Med Chem , vol.41 , Issue.19 , pp. 3690-3698
    • Koren, A.O.1    Horti, A.G.2    Mukhin, A.G.3
  • 27
    • 19944428892 scopus 로고    scopus 로고
    • Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography
    • Vaupel DB, Tella SR, Huso DL, et al. Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography. J Pharmacol Exp Ther 2005; 312(1): 355-65.
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.1 , pp. 355-365
    • Vaupel, D.B.1    Tella, S.R.2    Huso, D.L.3
  • 28
    • 0038654355 scopus 로고    scopus 로고
    • Biodistribution and radiation dosimetry of 18F-fluoro-A-85380 in healthy volunteers
    • Bottlaender M, Valette H, Roumenov D, et al. Biodistribution and radiation dosimetry of 18F-fluoro-A-85380 in healthy volunteers. J Nucl Med 2003; 44(4): 596-601.
    • (2003) J Nucl Med , vol.44 , Issue.4 , pp. 596-601
    • Bottlaender, M.1    Valette, H.2    Roumenov, D.3
  • 29
    • 0037927968 scopus 로고    scopus 로고
    • 2-[18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans
    • Kimes AS, Horti AG, London ED, et al. 2-[18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans. Faseb J 2003; 17(10): 1331-3.
    • (2003) Faseb J , vol.17 , Issue.10 , pp. 1331-1333
    • Kimes, A.S.1    Horti, A.G.2    London, E.D.3
  • 30
    • 33845940861 scopus 로고    scopus 로고
    • Stoichiometry and pharmacology of two human alpha4beta2 nicotinic receptor types
    • Moroni M, Bermudez I. Stoichiometry and pharmacology of two human alpha4beta2 nicotinic receptor types. J Mol Neurosci 2006; 30(1-2): 95-6.
    • (2006) J Mol Neurosci , vol.30 , Issue.1-2 , pp. 95-96
    • Moroni, M.1    Bermudez, I.2
  • 31
    • 0042332182 scopus 로고    scopus 로고
    • Self-administration of 5-iodo-A-85380, a beta2-selective nicotinic receptor ligand, by operantly trained rats
    • Liu X, Koren AO, Yee SK, Pechnick RN, Poland RE, London ED. Self-administration of 5-iodo-A-85380, a beta2-selective nicotinic receptor ligand, by operantly trained rats. Neuroreport 2003; 14(11): 1503-5.
    • (2003) Neuroreport , vol.14 , Issue.11 , pp. 1503-1505
    • Liu, X.1    Koren, A.O.2    Yee, S.K.3    Pechnick, R.N.4    Poland, R.E.5    London, E.D.6
  • 32
    • 0342905448 scopus 로고    scopus 로고
    • 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors
    • Mukhin AG, Gundisch D, Horti AG, et al. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol 2000; 57(3): 642-9.
    • (2000) Mol Pharmacol , vol.57 , Issue.3 , pp. 642-649
    • Mukhin, A.G.1    Gundisch, D.2    Horti, A.G.3
  • 33
    • 0033578078 scopus 로고    scopus 로고
    • Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A new positron emission tomography ligand for nicotinic receptors
    • Doll F, Dolci L, Valette H, et al. Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: a new positron emission tomography ligand for nicotinic receptors. J Med Chem 1999; 42(12): 2251-9.
    • (1999) J Med Chem , vol.42 , Issue.12 , pp. 2251-2259
    • Doll, F.1    Dolci, L.2    Valette, H.3
  • 34
    • 0033601478 scopus 로고    scopus 로고
    • Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy] pyridine in vivo
    • Valette H, Bottlaender M, Dolle F, et al. Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy] pyridine in vivo. Life Sci 1999; 64(5): PL93-7.
    • (1999) Life Sci , vol.64 , Issue.5
    • Valette, H.1    Bottlaender, M.2    Dolle, F.3
  • 35
    • 0031593889 scopus 로고    scopus 로고
    • 2-[18F]Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors
    • Horti AG, Scheffel U, Koren AO, et al. 2-[18F]Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors. Nucl Med Biol 1998; 25(7): 599-603.
    • (1998) Nucl Med Biol , vol.25 , Issue.7 , pp. 599-603
    • Horti, A.G.1    Scheffel, U.2    Koren, A.O.3
  • 36
    • 0032562411 scopus 로고    scopus 로고
    • 5-[I-125/123]lodo- 3(2(S)-azetidinylmethoxy)pyridine, a radioiodinated analog of A-85380 for in vivo studies of central nicotinic acetylcholine receptors
    • Musachio JL, Scheffel U, Finley PA, et al. 5-[I-125/123]lodo- 3(2(S)-azetidinylmethoxy)pyridine, a radioiodinated analog of A-85380 for in vivo studies of central nicotinic acetylcholine receptors. Life Sci 1998; 62(22): PL351-7.
    • (1998) Life Sci , vol.62 , Issue.22
    • Musachio, J.L.1    Scheffel, U.2    Finley, P.A.3
  • 37
    • 0032513990 scopus 로고    scopus 로고
    • In vivo studies with [125I]5-I-A-85380, a nicotinic acetylcholine receptor radioligand
    • Vaupel DB, Mukhin AG, Kimes AS, Horti AG, Koren AO, London ED. In vivo studies with [125I]5-I-A-85380, a nicotinic acetylcholine receptor radioligand. Neuroreport 1998; 9(10): 2311-7.
    • (1998) Neuroreport , vol.9 , Issue.10 , pp. 2311-2317
    • Vaupel, D.B.1    Mukhin, A.G.2    Kimes, A.S.3    Horti, A.G.4    Koren, A.O.5    London, E.D.6
  • 38
    • 0032515198 scopus 로고    scopus 로고
    • In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography
    • Chefer SI, Horti AG, Lee KS, Koren AO, Jones DW, Gorey JG, et al. In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography. Life Sci 1998; 63(25): PL355-60.
    • (1998) Life Sci , vol.63 , Issue.25
    • Chefer, S.I.1    Horti, A.G.2    Lee, K.S.3    Koren, A.O.4    Jones, D.W.5    Gorey, J.G.6
  • 39
    • 0346995472 scopus 로고    scopus 로고
    • Quantitative mapping of cerebral deoxyhemoglobin content using MR imaging
    • Fujita N, Shinohara M, Tanaka H, Yutani K, Nakamura H, Murase K. Quantitative mapping of cerebral deoxyhemoglobin content using MR imaging. Neuroimage 2003; 20(4): 2071-83.
    • (2003) Neuroimage , vol.20 , Issue.4 , pp. 2071-2083
    • Fujita, N.1    Shinohara, M.2    Tanaka, H.3    Yutani, K.4    Nakamura, H.5    Murase, K.6
  • 40
    • 63149179698 scopus 로고    scopus 로고
    • Central in vivo nicotinic acetylcholine receptor imaging agents for positron emission tomography (PET) and single photon emission computed tomography (SPECT)
    • Ogawa M, Tsukada H, Hatano K, Ouchi Y, Saji H, Magata Y. Central in vivo nicotinic acetylcholine receptor imaging agents for positron emission tomography (PET) and single photon emission computed tomography (SPECT). Biol Pharm Bull 2009; 32(3): 337-40.
    • (2009) Biol Pharm Bull , vol.32 , Issue.3 , pp. 337-340
    • Ogawa, M.1    Tsukada, H.2    Hatano, K.3    Ouchi, Y.4    Saji, H.5    Magata, Y.6
  • 42
    • 0036169966 scopus 로고    scopus 로고
    • Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects
    • Fujita M, Seibyl JP, Vaupel DB, et al. Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects. Eur J Nucl Med Mol Imaging 2002; 29(2): 183-90.
    • (2002) Eur J Nucl Med Mol Imaging , vol.29 , Issue.2 , pp. 183-190
    • Fujita, M.1    Seibyl, J.P.2    Vaupel, D.B.3
  • 43
    • 4143054599 scopus 로고    scopus 로고
    • 5-[123I]Iodo-A-85380: Assessment of pharmacological safety, radiation dosimetry and SPECT imaging of brain nicotinic receptors in healthy human subjects
    • Ueda M, Iida Y, Mukai T, et al. 5-[123I]Iodo-A-85380: assessment of pharmacological safety, radiation dosimetry and SPECT imaging of brain nicotinic receptors in healthy human subjects. Ann Nucl Med 2004; 18(4): 337-44.
    • (2004) Ann Nucl Med , vol.18 , Issue.4 , pp. 337-344
    • Ueda, M.1    Iida, Y.2    Mukai, T.3
  • 44
    • 15844383850 scopus 로고    scopus 로고
    • In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18Ffluoro- A-85380 and PET
    • Gallezot JD, Bottlaender M, Gregoire MC, et al. In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18Ffluoro- A-85380 and PET. J Nucl Med 2005; 46(2): 240-7.
    • (2005) J Nucl Med , vol.46 , Issue.2 , pp. 240-247
    • Gallezot, J.D.1    Bottlaender, M.2    Gregoire, M.C.3
  • 45
    • 0346103816 scopus 로고    scopus 로고
    • Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET
    • Fujita M, Ichise M, van Dyck CH, et al. Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET. Eur J Nucl Med Mol Imaging 2003; 30(12): 1620-9.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , Issue.12 , pp. 1620-1629
    • Fujita, M.1    Ichise, M.2    van Dyck, C.H.3
  • 46
    • 35348825596 scopus 로고    scopus 로고
    • 123I-5-IA-85380 SPECT imaging of nicotinic acetylcholine receptor availability in nonsmokers: Effects of sex and menstrual phase
    • Cosgrove KP, Mitsis EM, Bois F, et al. 123I-5-IA-85380 SPECT imaging of nicotinic acetylcholine receptor availability in nonsmokers: effects of sex and menstrual phase. J Nucl Med 2007; 48(10): 1633-40.
    • (2007) J Nucl Med , vol.48 , Issue.10 , pp. 1633-1640
    • Cosgrove, K.P.1    Mitsis, E.M.2    Bois, F.3
  • 47
    • 67650507507 scopus 로고    scopus 로고
    • Age-related decline in nicotinic receptor availability with [(123)I]5-IA-85380 SPECT
    • Mitsis EM, Cosgrove KP, Staley JK, et al. Age-related decline in nicotinic receptor availability with [(123)I]5-IA-85380 SPECT. Neurobiol Aging 2009; 30(9): 1490-7.
    • (2009) Neurobiol Aging , vol.30 , Issue.9 , pp. 1490-1497
    • Mitsis, E.M.1    Cosgrove, K.P.2    Staley, J.K.3
  • 48
    • 68049130974 scopus 로고    scopus 로고
    • The relationship between nicotinic receptors and cognitive functioning in healthy aging: An in vivo positron emission tomography (PET) study with 2-[(18)F]fluoro-A-85380
    • Ellis JR, Nathan PJ, Villemagne VL, et al. The relationship between nicotinic receptors and cognitive functioning in healthy aging: An in vivo positron emission tomography (PET) study with 2-[(18)F]fluoro-A-85380. Synapse 2009; 63(9): 752-63.
    • (2009) Synapse , vol.63 , Issue.9 , pp. 752-763
    • Ellis, J.R.1    Nathan, P.J.2    Villemagne, V.L.3
  • 49
    • 41649113294 scopus 로고    scopus 로고
    • Beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder
    • Czermak C, Staley JK, Kasserman S, et al. beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder. Int J Neuropsychopharmacol 2008; 11(3): 419-24.
    • (2008) Int J Neuropsychopharmacol , vol.11 , Issue.3 , pp. 419-424
    • Czermak, C.1    Staley, J.K.2    Kasserman, S.3
  • 50
    • 77956909315 scopus 로고    scopus 로고
    • 5-(123)I-A-85380 binding to the alpha4beta2-nicotinic receptor in mild cognitive impairment
    • Terriere E, Dempsey MF, Herrmann LL, et al. 5-(123)I-A-85380 binding to the alpha4beta2-nicotinic receptor in mild cognitive impairment. Neurobiol Aging 2010; 31(11): 1885-93.
    • (2010) Neurobiol Aging , vol.31 , Issue.11 , pp. 1885-1893
    • Terriere, E.1    Dempsey, M.F.2    Herrmann, L.L.3
  • 51
    • 33947721287 scopus 로고    scopus 로고
    • Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography
    • O'Brien JT, Colloby SJ, Pakrasi S, et al. Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography. J Neurol Neurosurg Psychiatry 2007; 78(4): 356-62.
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , Issue.4 , pp. 356-362
    • O'Brien, J.T.1    Colloby, S.J.2    Pakrasi, S.3
  • 52
    • 40349093080 scopus 로고    scopus 로고
    • Alpha4beta2-nicotinic receptor binding with 5-IA in Alzheimer's disease: Methods of scan analysis
    • Terriere E, Sharman M, Donaghey C, et al. alpha4beta2-nicotinic receptor binding with 5-IA in Alzheimer's disease: methods of scan analysis. Neurochem Res 2008; 33(4): 643-51.
    • (2008) Neurochem Res , vol.33 , Issue.4 , pp. 643-651
    • Terriere, E.1    Sharman, M.2    Donaghey, C.3
  • 53
    • 48549104780 scopus 로고    scopus 로고
    • Relationship between nicotinic receptors and cognitive function in early Alzheimer's disease: A 2-[18F] fluoro-A-85380 PET study
    • Ellis JR, Villemagne VL, Nathan PJ, et al. Relationship between nicotinic receptors and cognitive function in early Alzheimer's disease: a 2-[18F] fluoro-A-85380 PET study. Neurobiol Learn Mem 2008; 90(2): 404-12.
    • (2008) Neurobiol Learn Mem , vol.90 , Issue.2 , pp. 404-412
    • Ellis, J.R.1    Villemagne, V.L.2    Nathan, P.J.3
  • 54
    • 59449106158 scopus 로고    scopus 로고
    • Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET
    • Ellis JR, Nathan PJ, Villemagne VL, et al. Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET. Psychopharmacology (Berl) 2009; 202(1-3): 79-91.
    • (2009) Psychopharmacology (Berl) , vol.202 , Issue.1-3 , pp. 79-91
    • Ellis, J.R.1    Nathan, P.J.2    Villemagne, V.L.3
  • 56
    • 33746922400 scopus 로고    scopus 로고
    • Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors
    • Brody AL, Mandelkern MA, London ED, et al. Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors. Arch Gen Psychiatry. 2006; 63(8):907-15.
    • (2006) Arch Gen Psychiatry , vol.63 , Issue.8 , pp. 907-915
    • Brody, A.L.1    Mandelkern, M.A.2    London, E.D.3
  • 57
    • 66449116640 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptor occupancy: Effect of smoking a denicotinized cigarette
    • Brody AL, Mandelkern MA, Costello MR, et al. Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette. Int J Neuropsychopharmacol 2009; 12(3): 305-16.
    • (2009) Int J Neuropsychopharmacol , vol.12 , Issue.3 , pp. 305-316
    • Brody, A.L.1    Mandelkern, M.A.2    Costello, M.R.3
  • 58
    • 37549031240 scopus 로고    scopus 로고
    • Smoking upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain
    • Wullner U, Gundisch D, Herzog H, et al. Smoking upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain. Neurosci Lett 2008; 430(1): 34-7.
    • (2008) Neurosci Lett , vol.430 , Issue.1 , pp. 34-37
    • Wullner, U.1    Gundisch, D.2    Herzog, H.3
  • 59
    • 33748282547 scopus 로고    scopus 로고
    • Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers
    • Staley JK, Krishnan-Sarin S, Cosgrove KP, et al. Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. J Neurosci 2006; 26(34): 8707-14.
    • (2006) J Neurosci , vol.26 , Issue.34 , pp. 8707-8714
    • Staley, J.K.1    Krishnan-Sarin, S.2    Cosgrove, K.P.3
  • 60
    • 66449133837 scopus 로고    scopus 로고
    • Beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking
    • Cosgrove KP, Batis J, Bois F, et al. beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking. Arch Gen Psychiatry 2009; 66(6): 666-76.
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.6 , pp. 666-676
    • Cosgrove, K.P.1    Batis, J.2    Bois, F.3
  • 61
    • 36049038636 scopus 로고    scopus 로고
    • Temporal change in human nicotinic acetylcholine receptor after smoking cessation: 5IA SPECT study
    • Mamede M, Ishizu K, Ueda M, et al. Temporal change in human nicotinic acetylcholine receptor after smoking cessation: 5IA SPECT study. J Nucl Med 2007; 48(11): 1829-35.
    • (2007) J Nucl Med , vol.48 , Issue.11 , pp. 1829-1835
    • Mamede, M.1    Ishizu, K.2    Ueda, M.3
  • 62
    • 53749101043 scopus 로고    scopus 로고
    • Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: A PET study with 2-18F-FA-85380
    • Mukhin AG, Kimes AS, Chefer SI, et al. Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380. J Nucl Med 2008; 49(10): 1628-35.
    • (2008) J Nucl Med , vol.49 , Issue.10 , pp. 1628-1635
    • Mukhin, A.G.1    Kimes, A.S.2    Chefer, S.I.3
  • 63
    • 33747889356 scopus 로고    scopus 로고
    • Alteration of the in vivo nicotinic receptor density in ADNFLE patients: A PET study
    • Picard F, Bruel D, Servent D, et al. Alteration of the in vivo nicotinic receptor density in ADNFLE patients: a PET study. Brain 2006; 129(Pt 8): 2047-60.
    • (2006) Brain , vol.129 , Issue.PART 8 , pp. 2047-2060
    • Picard, F.1    Bruel, D.2    Servent, D.3
  • 64
    • 20844441945 scopus 로고    scopus 로고
    • Varenicline: An alpha4beta2 nicotinic receptor partial agonist for smoking cessation
    • Coe JW, Brooks PR, Vetelino MG, et al. Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem 2005; 48(10): 3474-7.
    • (2005) J Med Chem , vol.48 , Issue.10 , pp. 3474-3477
    • Coe, J.W.1    Brooks, P.R.2    Vetelino, M.G.3
  • 65
    • 62749191187 scopus 로고    scopus 로고
    • Baseline expression of alpha4beta2* nicotinic acetylcholine receptors predicts motivation to self-administer nicotine
    • Le Foll B, Chefer SI, Kimes AS, et al. Baseline expression of alpha4beta2* nicotinic acetylcholine receptors predicts motivation to self-administer nicotine. Biol Psychiatry 2009; 65(8): 714-6.
    • (2009) Biol Psychiatry , vol.65 , Issue.8 , pp. 714-716
    • Le Foll, B.1    Chefer, S.I.2    Kimes, A.S.3
  • 66
    • 33947593200 scopus 로고    scopus 로고
    • ACS. American Cancer Society, [cited 2009 July 26], Available from
    • ACS. American Cancer Society. Cancer Facts and Figures 2007. 2007 [cited 2009 July 26]; Available from: http://www.cancer.org.
    • (2007) Cancer Facts and Figures 2007
  • 67
    • 1542347858 scopus 로고    scopus 로고
    • Actual causes of death in the United States, 2000
    • Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. Jama 2004; 291(10): 1238-45.
    • (2004) Jama , vol.291 , Issue.10 , pp. 1238-1245
    • Mokdad, A.H.1    Marks, J.S.2    Stroup, D.F.3    Gerberding, J.L.4
  • 68
    • 0029855810 scopus 로고    scopus 로고
    • Maternal cigarette smoking as a risk factor for placental abruption, placenta previa, and uterine bleeding in pregnancy
    • Ananth CV, Savitz DA, Luther ER. Maternal cigarette smoking as a risk factor for placental abruption, placenta previa, and uterine bleeding in pregnancy. Am J Epidemiol 1996; 144(9): 881-9.
    • (1996) Am J Epidemiol , vol.144 , Issue.9 , pp. 881-889
    • Ananth, C.V.1    Savitz, D.A.2    Luther, E.R.3
  • 69
    • 0012607259 scopus 로고    scopus 로고
    • NSDUH, Results from the 2007 National Survey on Drug Use and Health: National Findings
    • NSDUH. Substance Abuse and Mental Health Services Administration. Results from the 2007 National Survey on Drug Use and Health: National Findings. 2008.
    • (2008) Substance Abuse and Mental Health Services Administration
  • 70
    • 70350633509 scopus 로고    scopus 로고
    • Orbitofrontal Cortex and Drug Use during Adolescence: Role of Prenatal Exposure to Maternal Smoking and BDNF Genotype
    • Lotfipour S, Leonard G, Perron M, et al. Orbitofrontal Cortex and Drug Use during Adolescence: Role of Prenatal Exposure to Maternal Smoking and BDNF Genotype. Archives of General Psychiatry 2009; 66(11): 1244-52.
    • (2009) Archives of General Psychiatry , vol.66 , Issue.11 , pp. 1244-1252
    • Lotfipour, S.1    Leonard, G.2    Perron, M.3
  • 71
    • 72949124435 scopus 로고    scopus 로고
    • Prenatal Exposure to Maternal Cigarette Smoking Interacts With a Polymorphism in the α6 Nicotinic Acetylcholine Receptor Gene to Influence Drug Use and Striatum Volume in Adolescence
    • Lotfipour S, Leonard G, Perron M, et al. Prenatal Exposure to Maternal Cigarette Smoking Interacts With a Polymorphism in the α6 Nicotinic Acetylcholine Receptor Gene to Influence Drug Use and Striatum Volume in Adolescence. Molecular Psychiatry. 2010; 15(1): 6-8.
    • (2010) Molecular Psychiatry , vol.15 , Issue.1 , pp. 6-8
    • Lotfipour, S.1    Leonard, G.2    Perron, M.3
  • 72
    • 15744394202 scopus 로고    scopus 로고
    • Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum
    • Falk L, Nordberg A, Seiger A, Kjaeldgaard A, Hellstrom-Lindahl E. Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum. Neuroscience 2005; 132(2): 389-97.
    • (2005) Neuroscience , vol.132 , Issue.2 , pp. 389-397
    • Falk, L.1    Nordberg, A.2    Seiger, A.3    Kjaeldgaard, A.4    Hellstrom-Lindahl, E.5
  • 73
    • 0031863354 scopus 로고    scopus 로고
    • Fetal nicotine or cocaine exposure: Which one is worse?
    • Slotkin TA. Fetal nicotine or cocaine exposure: which one is worse? J Pharmacol Exp Ther 1998; 285(3): 931-45.
    • (1998) J Pharmacol Exp Ther , vol.285 , Issue.3 , pp. 931-945
    • Slotkin, T.A.1
  • 75
    • 34547510182 scopus 로고    scopus 로고
    • Separate or sequential exposure to nicotine prenatally and in adulthood: Persistent effects on acetylcholine systems in rat brain regions
    • Slotkin TA, Ryde IT, Seidler FJ. Separate or sequential exposure to nicotine prenatally and in adulthood: persistent effects on acetylcholine systems in rat brain regions. Brain Res Bull 2007; 74(1-3): 91-103.
    • (2007) Brain Res Bull , vol.74 , Issue.1-3 , pp. 91-103
    • Slotkin, T.A.1    Ryde, I.T.2    Seidler, F.J.3
  • 76
    • 0037186703 scopus 로고    scopus 로고
    • Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain
    • Slotkin TA, Pinkerton KE, Auman JT, Qiao D, Seidler FJ. Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. Brain Res Dev Brain Res 2002; 133(2): 175-9.
    • (2002) Brain Res Dev Brain Res , vol.133 , Issue.2 , pp. 175-179
    • Slotkin, T.A.1    Pinkerton, K.E.2    Auman, J.T.3    Qiao, D.4    Seidler, F.J.5
  • 77
    • 0023159935 scopus 로고
    • Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions
    • Slotkin TA, Orband-Miller L, Queen KL. Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions. J Pharmacol Exp Ther 1987; 242(1): 232-7.
    • (1987) J Pharmacol Exp Ther , vol.242 , Issue.1 , pp. 232-237
    • Slotkin, T.A.1    Orband-Miller, L.2    Queen, K.L.3
  • 78
    • 19944379789 scopus 로고    scopus 로고
    • Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: Neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys
    • Slotkin TA, Seidler FJ, Qiao D, et al. Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. Neuropsychopharmacology. 2005; 30(1): 129-44.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.1 , pp. 129-144
    • Slotkin, T.A.1    Seidler, F.J.2    Qiao, D.3
  • 79
    • 11144316764 scopus 로고    scopus 로고
    • Nicotine therapy in adulthood reverses the synaptic and behavioral deficits elicited by prenatal exposure to phenobarbital
    • Beer A, Slotkin TA, Seidler FJ, Aldridge JE, Yanai J. Nicotine therapy in adulthood reverses the synaptic and behavioral deficits elicited by prenatal exposure to phenobarbital. Neuropsychopharmacology 2005; 30(1): 156-65.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.1 , pp. 156-165
    • Beer, A.1    Slotkin, T.A.2    Seidler, F.J.3    Aldridge, J.E.4    Yanai, J.5
  • 80
    • 1942516979 scopus 로고    scopus 로고
    • Prenatal nicotine exposure alters the response to nicotine administration in adolescence: Effects on cholinergic systems during exposure and withdrawal
    • Abreu-Villaca Y, Seidler FJ, Tate CA, Cousins MM, Slotkin TA. Prenatal nicotine exposure alters the response to nicotine administration in adolescence: effects on cholinergic systems during exposure and withdrawal. Neuropsychopharmacology 2004; 29(5): 879-90.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.5 , pp. 879-890
    • Abreu-Villaca, Y.1    Seidler, F.J.2    Tate, C.A.3    Cousins, M.M.4    Slotkin, T.A.5
  • 81
    • 0035882033 scopus 로고    scopus 로고
    • Nicotine-induced alterations in the expression of nicotinic receptors in primary cultures from human prenatal brain
    • Hellstrom-Lindahl E, Seiger A, Kjaeldgaard A, Nordberg A. Nicotine-induced alterations in the expression of nicotinic receptors in primary cultures from human prenatal brain. Neuroscience 2001; 105(3): 527-34.
    • (2001) Neuroscience , vol.105 , Issue.3 , pp. 527-534
    • Hellstrom-Lindahl, E.1    Seiger, A.2    Kjaeldgaard, A.3    Nordberg, A.4
  • 82
    • 34249829610 scopus 로고    scopus 로고
    • Genes, maternal smoking, and the offspring brain and body during adolescence: Design of the Saguenay Youth Study
    • Pausova Z, Paus T, Abrahamowicz M, et al. Genes, maternal smoking, and the offspring brain and body during adolescence: design of the Saguenay Youth Study. Hum Brain Mapp 2007; 28(6): 502-18.
    • (2007) Hum Brain Mapp , vol.28 , Issue.6 , pp. 502-518
    • Pausova, Z.1    Paus, T.2    Abrahamowicz, M.3
  • 83
    • 33746036112 scopus 로고    scopus 로고
    • Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials
    • Shankar LK, Hoffman JM, Bacharach S, Graham MM, Karp J, Lammertsma AA, et al. Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials. J Nucl Med 2006; 47(6): 1059-66.
    • (2006) J Nucl Med , vol.47 , Issue.6 , pp. 1059-1066
    • Shankar, L.K.1    Hoffman, J.M.2    Bacharach, S.3    Graham, M.M.4    Karp, J.5    Lammertsma, A.A.6


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