ESeroS-GS modulates lipopolysaccharide-induced macrophage activation by impairing the assembly of TLR-4 complexes in lipid rafts

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 5, 2011, Pages 772-783

  Duan, Wenjuan ^a,b   Zhou, Juefei ^a,c   Zhang, Shen ^a,d   Zhao, Kai ^a   Zhao, Lijing ^a,b   Ogata, Kazumi ^e   Sakaue, Takahiro ^e   Mori, Akitane ^f   Wei, Taotao ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Chengdu Institute of Biological Products   (China)

^d HUAIHUA MEDICAL COLLEGE   (China)

^e SENJU PHARMACEUTICAL CO LTD   (Japan)

^f OKAYAMA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ESeroS GS; Lipid raft; Lipopolysaccharide; RAW264.7 macrophage; Toll like receptor 4

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; CD14 ANTIGEN; GAMMA GLUTAMYL [2 [[[3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2 (4,8,12 TRIMETHYLTRIDECYL) 2H 1 BENZOPYRAN 6 YL]OXY]CARBONYL]] 3 [[[2 (1H INDOL 3 YL)ETHYL]AMINO] 3 OXOPROPYL]CYSTEINYLGLYCINE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SODIUM; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DOWN REGULATION; DRUG INHIBITION; DRUG MECHANISM; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIPID RAFT; MACROPHAGE ACTIVATION; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; REPORTER GENE; SEPSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; ANTIGENS, CD14; BENZOPYRANS; CELL LINE; CYTOKINES; DOWN-REGULATION; FLUORESCEIN-5-ISOTHIOCYANATE; I-KAPPA B KINASE; INDOLES; INFLAMMATION MEDIATORS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; LONGEVITY; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MAP KINASE KINASE KINASES; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; SEPSIS; TOLL-LIKE RECEPTOR 4;

EID: 79955651829     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.01.019     Document Type: Article

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