Prodelphinidin B-4 3′-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-κB pathway

Biochemical Pharmacology

Volumn 74, Issue 5, 2007, Pages 742-751

  Hou, De Xing ^a   Luo, Dong ^a   Tanigawa, Shunsuke ^a   Hashimoto, Fumio ^a   Uto, Takuhiro ^a   Masuzaki, Satoko ^a   Fujii, Makoto ^a   Sakata, Yusuke ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

COX 2; IKK ; iNOS; NF B; Proanthocyanidin; TAK1

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC ACID; POLYPHENOL DERIVATIVE; PRODELPHINIDIN B 4 3' O GALLATE; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DEGRADATION; DOSE RESPONSE; DOWN REGULATION; GEL MOBILITY SHIFT ASSAY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; NONHUMAN; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEA;

ANIMALS; ANTHOCYANINS; CARRIER PROTEINS; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DOWN-REGULATION; FLAVONOIDS; I-KAPPA B KINASE; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHENOLS; PROTEIN TRANSPORT; RNA, MESSENGER; TEA;

EID: 34447650269     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.06.006     Document Type: Article

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