Novel tandem biotransformation process for the biosynthesis of a novel compound, 4-(2,3,5,6-Tetramethylpyrazine-1)-4'-Demethylepipodophyllotoxin

Applied and Environmental Microbiology

Volumn 77, Issue 9, 2011, Pages 3023-3034

  Tang, Ya Jie ^a,b,c,d   Zhao, Wei ^a,b   Li, Hong Mei ^a,b  

^a HUBEI UNIVERSITY OF TECHNOLOGY   (China)

^b SHANGHAI ADVANCED RESEARCH INSTITUTE   (China)

^c INSTITUTE OF PROCESS ENGINEERING   (China)

^d EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNARIA ALTERNATA; ANTI-TUMOR ACTIVITIES; BIOTRANSFORMATION PROCESS; BOTANICAL GARDENS; CHINESE ACADEMY OF SCIENCES; DEMETHYLATION; EFFECTIVE CONCENTRATION; EPITHELIAL CELLS; GIBBERELLA FUJIKUROI; HUMUS SOILS; HYDROXYL GROUPS; LIGUSTRAZINE; METHOXYL GROUPS; PODOPHYLLOTOXIN; STRUCTURE-FUNCTION RELATIONSHIP; TRANSAMINATION REACTION; TUMOR CELL LINES; WATER SOLUBILITIES;

BIOCHEMISTRY; BIOCONVERSION; CELL CULTURE; SOILS;

THERMOMECHANICAL PULPING PROCESS;

ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; FUNGAL DNA; FUNGAL RNA; PODOPHYLLOTOXIN; PYRAZINE DERIVATIVE; RIBOSOME DNA; RNA 18S;

BIOTRANSFORMATION; FOREST SOIL; FUNGAL DISEASE; HUMUS; PATHOTYPE; SUBSTRATE; TOXIN; TUMOR;

ALTERNARIA; ARTICLE; BERBERIDACEAE; BIOTRANSFORMATION; CELL SURVIVAL; CHEMISTRY; CHINA; DNA SEQUENCE; DRUG EFFECT; GENETICS; GIBBERELLA; HUMAN; IC 50; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RNA GENE; TUMOR CELL LINE;

ALTERNARIA; ANTINEOPLASTIC AGENTS; BERBERIDACEAE; BIOTRANSFORMATION; CELL LINE, TUMOR; CELL SURVIVAL; CHINA; DNA, FUNGAL; DNA, RIBOSOMAL; GENES, RRNA; GIBBERELLA; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR SEQUENCE DATA; PODOPHYLLOTOXIN; PYRAZINES; RNA, FUNGAL; RNA, RIBOSOMAL, 18S; SEQUENCE ANALYSIS, DNA; SOIL MICROBIOLOGY;

BIOCHEMISTRY; BIOSYNTHESIS; CELLS; CULTURE MEDIA; SOIL; THERMOMECHANICAL PULPING;

CHINA; HUBEI;

ALTERNARIA ALTERNATA; DYSOSMA VERSIPELLIS; GIBBERELLA FUJIKUROI;

EID: 79955633413     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.03047-10     Document Type: Article

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