Novel 4β-anilino-podophyllotoxin derivatives: Design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents

Molecular BioSystems

Volumn 6, Issue 2, 2010, Pages 410-420

  Hu, Chunqi ^a   Xu, Danqing ^a   Du, Wenting ^a   Qian, Shijing ^a   Wang, Li ^a   Lou, Jianshu ^a   He, Qiaojun ^a   Yang, Bo ^a   Hu, Yongzhou ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ABCB1 PROTEIN, HUMAN; ANILINE DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); DRUG DERIVATIVE; ENZYME INHIBITOR; ETOPOSIDE; GLYCOPROTEIN P; PODOPHYLLOTOXIN;

ANIMAL; APOPTOSIS; ARTICLE; CELL CYCLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; GENETICS; HUMAN; METABOLISM; MOUSE; NEOPLASM; SYNTHESIS; TUMOR CELL LINE;

ANILINE COMPOUNDS; ANIMALS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; ETOPOSIDE; HUMANS; MICE; NEOPLASMS; P-GLYCOPROTEIN; PODOPHYLLOTOXIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 75749110524     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/b912336a     Document Type: Article

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