Antitumor agents. Part 227: Studies on novel 4′-O-demethyl- epipodophyllotoxins as antitumor agents targeting topoisomerase II

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 12, 2004, Pages 3339-3344

  Xiao, Zhiyan ^a   Bastow, Kenneth F ^a   Vance, John R ^b   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b Plantaceutica Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPIPODOPHYLLOTOXIN DERIVATIVE; ETOPOSIDE; GL 331; GYRASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL DESTRUCTION; CELL KILLING; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TUMOR; DNA; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; HUMANS; MOLECULAR STRUCTURE; PODOPHYLLOTOXIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 2542478114     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.067     Document Type: Article

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