Chromium (VI)-induced oxidative stress and apoptosis is reduced by garlic and its derivative S-allylcysteine through the activation of Nrf2 in the hepatocytes of Wistar rats

Journal of Applied Toxicology

Volumn 28, Issue 7, 2008, Pages 908-919

  Kalayarasan, Srinivasan ^a   Sriram, Narayanan ^a   Sureshkumar, Ananthasadagopan ^a   Sudhandiran, Ganapasam ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Apoptosis; Aqueous garlic extract (AGE); K2Cr2O7; Lipid peroxidation; Liver; Nrf2; Oxidative stress; Phase II enzymes; Reactive oxygen species; S allylcysteine (SAC)

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CATALASE; DICHROMATE POTASSIUM; GARLIC EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; LIPOCORTIN 5; REACTIVE OXYGEN METABOLITE; S ALLYLCYSTEINE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL PROTECTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVITY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LIVER CELL; MALE; NONHUMAN; NORMAL VALUE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSMISSION ELECTRON MICROSCOPY; VITAMIN BLOOD LEVEL; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARCINOGENS, ENVIRONMENTAL; CAUSTICS; CHROMIUM; CYSTEINE; GARLIC; HEPATOCYTES; MALE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PLANT EXTRACTS; POTASSIUM DICHROMATE; RATS; RATS, WISTAR;

ALLIUM SATIVUM; RATTUS NORVEGICUS;

EID: 55449101207     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1355     Document Type: Article

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