Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 17, 2011, Pages 6939-6944

  Zhang, Zhongtao ^a   Cheng, Bokun ^a   Tse Dinh, Yuk Ching ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Cytosine recognition; DNA relaxation; Protein DNA complex; TopA

Indexed keywords

CYTOSINE; DNA TOPOISOMERASE; OLIGONUCLEOTIDE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA CLEAVAGE; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION;

AMINO ACID SUBSTITUTION; CRYSTALLOGRAPHY, X-RAY; DNA TOPOISOMERASES, TYPE I; DNA, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MUTATION, MISSENSE; PROTEIN STRUCTURE, TERTIARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 79955566853     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1100300108     Document Type: Article

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