Site-directed mutagenesis of conserved aspartates, glutamates and arginines in the active site region of Escherichia coli DNA topoisomerase I

Journal of Biological Chemistry

Volumn 273, Issue 15, 1998, Pages 8783-8789

  Zhu, Chang Xi ^a   Roche, Camille J ^a   Papanicolaou, Nikolaos ^a   DiPietrantonio, Anna ^a   Tse Dinh, Yuk Ching ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; BACTERIAL ENZYME; DNA TOPOISOMERASE; GLUTAMIC ACID; PLASMID DNA;

ARTICLE; ENZYME ACTIVE SITE; ENZYME PURIFICATION; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; ASPARTIC ACID; BINDING SITES; DNA PRIMERS; DNA TOPOISOMERASES, TYPE I; ESCHERICHIA COLI; GLUTAMIC ACID; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, FLUORESCENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032502767     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.15.8783     Document Type: Article

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