UVA1 radiation inhibits calcineurin through oxidative damage mediated by photosensitization

Free Radical Biology and Medicine

Volumn 50, Issue 10, 2011, Pages 1392-1399

  Musson, Ruben E A ^a   Hensbergen, Paul J ^a   Westphal, Adrie H ^b   Temmink, Wouter P M ^a   Deelder, André M ^a   Van Pelt, Johannes ^a   Mullenders, Leon H F ^a   Smit, Nico P M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Calcineurin; Free radicals; NFAT; Oxidative stress; Skin; Tacrolimus; UVA radiation

Indexed keywords

CALCINEURIN; CYSTEINE; MANGANESE; METHIONINE; OXYGEN; PHOSPHOPROTEIN PHOSPHATASE 2A; SUPEROXIDE; TACROLIMUS;

ARTICLE; CONTROLLED STUDY; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PHOTOSENSITIZATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; RADIATION DOSE; RADIATION EXPOSURE; ULTRAVIOLET A RADIATION;

CALCINEURIN; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; OXIDATION-REDUCTION; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; SINGLET OXYGEN; SUPEROXIDES; ULTRAVIOLET RAYS;

EID: 79955482983     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.02.019     Document Type: Article

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