DNA repair in mononuclear cells: Role of serine/threonine phosphatases

Journal of Laboratory and Clinical Medicine

Volumn 140, Issue 4, 2002, Pages 255-262

  Herman, Michal ^a,b   Ori, Yaacov ^a,b   Chagnac, Avry ^a,b   Weinstein, Talia ^a,b   Korzets, Asher ^a,b   Zevin, Dina ^a,b   Malachi, Tsipora ^a,b   Gafter, Uzi ^a,b  

^a RABIN MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0036793127     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2002.127738     Document Type: Article

References (25)

1. London MJ, Farmery SM, Will EJ, Davison AM, Lodge JPA. Risk of neoplasia in renal transplant patients. Lancet 1995;346:403-6.
2. Bohr VA, Evans MK, Fornace AJ Jr. Biology of disease: DNA repair and its pathogenetic implications. J Lab Invest 1989;61:143-61.
3. Herman M, Weinstein T, Korzets A, Chagnac A, Ori Y, Zevin D, et al. Effect of cyclosporin A on DNA repair and cancer incidence in kidney-transplant recipients. J Lab Clin Med 2001;137:14-20.
4. Morris RE. Mechanisms of action of new immunosuppressive drugs. Kidney Int 1996;49:S26-38.
5. Liu J. FK506 and ciclosporin: molecular probes for studying intracellular signal transduction. Trends Pharmacol Sci 1993;14:182-8.
6. Carballo M, Marquez G, Conde M, Martin-Nieto J, Monteseirin J, Conde J. et al. Characterization of calcineurin in human neutrophils. J Biol Chem 1999;274:93-100.
7. Malachi T, Zevin D, Gafter U, Chagnac A, Slor H, Levi J. DNA repair and recovery of RNA synthesis in uremic patients. Kidney Int 1993;44:385-9.
8. Omura M, Yamaguchi M. Regulation of protein phosphatase activity by regucalcin localization in rat liver nuclei. J Cell Biochem 1999;75:437-45.
9. Li W, Handschumacher RE. Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones. Biochem Biophys Res Commun 1996;219:96-9.
10. Hunter T. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 1995;80:225-36.
11. Fruman DA, Klee CB, Bierer BE, Burakoff SJ. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A 1992;89:3686-90.
12. Gafter U, Malachi T, Ori Y, Breitbart H. The role of calcium in human lymphocyte DNA repair ability. J Lab Clin Med 1997;130:33-41.
13. 2+-mediated upregulation of the DNA repair enzyme DNA polymerase β in human peripheral blood mononuclear cells. Eur J Biochem 1999;264:952-9.
14. Charp PA, Regan JD. Inhibition of DNA repair by trifluoperazine. Biochem Biophys Acta 1985;824:34-9.
15. Aussel C, Breittmayer JP, Pelassy C, Bernard A. Calmodulin, a junction between two independent immunosuppresive pathways in Jurkat T cells. J Biol Chem 1995;270:8032-6.
16. Rusnak F, Beressi AH, Haddy A, Tefferi A. Calcineurin protein phosphatase activity in peripheral blood lymphocytes. Bone Marrow Transplant 1996;17:309-13.
17. Ariza RR, Keyse SM, Moggs JG, Wood RD. Reversible protein phosphorylation modulates nucleotide excision repair of damaged DNA by human cell extracts. Nucleic Acids Res 1996;24:433-40.
18. 2+ from intracellular stores in ECV304 endothelial cells. Cell Calcium 1997;21:461-7.
19. Allam A, Illges H. Calyculin A inhibits expression of CD8α but not CD4 in human peripheral blood cells. Immunobiology 2000;202:353-62.
20. Douglas P, Moorhead GB, Ye R, Lees-Miller SP. Protein phosphatases regulate DNA-dependent protein kinase activity. J Biol Chem 2001;276:18992-8.
21. Mailand N, Falck J, Lukas C, Syljuasen RG, Welcker M, Bartek J, et al. Rapid destruction of human Cdc25A in response to DNA damage. Science 2000;288:1425-9.
22. Bulavin DV, Higashimoto Y, Popoff IJ, Gaarde WA, Basrur V, Potapova O, et al. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 2001;411:102-7.
23. Whitehouse CJ, Taylor RM, Thistlethwaite A, Zhang H, Karimi-Busheri F, Lasko DD, et al. XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair. Cell 2001;104:107-17.
24. 2+ fluxes. J Lab Clin Med 1999;133:362-9.
25. 2+-induced p38/SAPK signalling inhibited by the immunosuppressant cyclosporin A in human peripheral blood mononuclear cells. Eur J Biochem 1999;265:1075-84.