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Volumn 100, Issue 6, 2007, Pages 1703-1712

Hydrogen peroxide triggers the proteolytic cleavage and the inactivation of calcineurin

Author keywords

Calcineurin; Hydrogen peroxide; Lysosomal protease; Nuclear factor of activated T cells; Reactive oxygen species

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CALCINEURIN; CALCIUM ION; CHLOROQUINE; HYDROGEN PEROXIDE; NUCLEAR FACTOR; PROTEINASE; REACTIVE OXYGEN METABOLITE;

EID: 33847761926     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04340.x     Document Type: Article
Times cited : (22)

References (44)
  • 2
    • 0034062098 scopus 로고    scopus 로고
    • Inactivation of calcineurin by hydrogen peroxide and phenylarsine oxide. Evidence for a dithiol-disulfide equilibrium and implications for redox regulation
    • Bogumil R., Namgaladze D., Schaarschmidt D., Schmachtel T., Hellstern S., Mutzel R. and Ullrich V. (2000) Inactivation of calcineurin by hydrogen peroxide and phenylarsine oxide. Evidence for a dithiol-disulfide equilibrium and implications for redox regulation. Eur. J. Biochem. 267, 1407-1415.
    • (2000) Eur. J. Biochem , vol.267 , pp. 1407-1415
    • Bogumil, R.1    Namgaladze, D.2    Schaarschmidt, D.3    Schmachtel, T.4    Hellstern, S.5    Mutzel, R.6    Ullrich, V.7
  • 3
    • 0028821967 scopus 로고
    • Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization
    • Brunk U. T., Zhang H., Dalen H. and Ollinger K. (1995) Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization. Free Radic. Biol. Med. 19, 813-822.
    • (1995) Free Radic. Biol. Med , vol.19 , pp. 813-822
    • Brunk, U.T.1    Zhang, H.2    Dalen, H.3    Ollinger, K.4
  • 5
    • 0344178211 scopus 로고    scopus 로고
    • Characterization of calcineurin in human neutrophils. Inhibitory effect of hydrogen peroxide on its enzyme activity and on NF-kappaB DNA binding
    • Carballo M., Marquez G., Conde M., Martin-Nieto J., Monteseirin J., Conde J., Pintado E. and Sobrino F. (1999) Characterization of calcineurin in human neutrophils. Inhibitory effect of hydrogen peroxide on its enzyme activity and on NF-kappaB DNA binding. J. Biol. Chem. 274, 93-100.
    • (1999) J. Biol. Chem , vol.274 , pp. 93-100
    • Carballo, M.1    Marquez, G.2    Conde, M.3    Martin-Nieto, J.4    Monteseirin, J.5    Conde, J.6    Pintado, E.7    Sobrino, F.8
  • 6
    • 0029097801 scopus 로고
    • Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin
    • Chang H. Y., Takei K., Sydor A. M., Born T., Rusnak F. and Jay D. G. (1995) Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. Nature 376, 686-690.
    • (1995) Nature , vol.376 , pp. 686-690
    • Chang, H.Y.1    Takei, K.2    Sydor, A.M.3    Born, T.4    Rusnak, F.5    Jay, D.G.6
  • 8
    • 0035951849 scopus 로고    scopus 로고
    • Calcium, calcineurin, and the control of transcription
    • Crabtree G. R. (2001) Calcium, calcineurin, and the control of transcription. J. Biol. Chem. 276, 2313-2316.
    • (2001) J. Biol. Chem , vol.276 , pp. 2313-2316
    • Crabtree, G.R.1
  • 11
    • 0033557724 scopus 로고    scopus 로고
    • Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway
    • Furuke K., Shiraishi M., Mostowski H. S. and Bloom E. T. (1999) Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway. J. Immunol. 162, 1988-1993.
    • (1999) J. Immunol , vol.162 , pp. 1988-1993
    • Furuke, K.1    Shiraishi, M.2    Mostowski, H.S.3    Bloom, E.T.4
  • 13
    • 0028848524 scopus 로고
    • Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
    • Kissinger C. R., Parge H. E., Knighton D. R. et al. (1995) Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature 378, 641-644.
    • (1995) Nature , vol.378 , pp. 641-644
    • Kissinger, C.R.1    Parge, H.E.2    Knighton, D.R.3
  • 14
    • 0029065517 scopus 로고
    • Potentiated necrosis of cultured cortical neurons by neurotrophins
    • Koh J. Y., Gwag B. J., Lobner D. and Choi D. W. (1995) Potentiated necrosis of cultured cortical neurons by neurotrophins. Science 268, 573-575.
    • (1995) Science , vol.268 , pp. 573-575
    • Koh, J.Y.1    Gwag, B.J.2    Lobner, D.3    Choi, D.W.4
  • 15
    • 0034595834 scopus 로고    scopus 로고
    • Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
    • Kusakawa G., Saito T., Onuki R., Ishiguro K., Kishimoto T. and Hisanaga S. (2000) Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. J. Biol. Chem. 275, 17 166-17 172.
    • (2000) J. Biol. Chem , vol.275
    • Kusakawa, G.1    Saito, T.2    Onuki, R.3    Ishiguro, K.4    Kishimoto, T.5    Hisanaga, S.6
  • 18
    • 0029981094 scopus 로고    scopus 로고
    • A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange
    • Lin X. and Barber D. L. (1996) A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. Proc. Natl Acad. Sci. USA 93, 12 631-12 636.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93
    • Lin, X.1    Barber, D.L.2
  • 19
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu J., Farmer J. D. Jr, Lane W. S., Friedman J., Weissman I. and Schreiber S. L. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer Jr, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 20
    • 27844553889 scopus 로고    scopus 로고
    • Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain
    • Liu F., Grundke-Iqbal I., Iqbal K., Oda Y., Tomizawa K. and Gong C. X. (2005) Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J. Biol. Chem. 280, 37 755-37 762.
    • (2005) J. Biol. Chem , vol.280
    • Liu, F.1    Grundke-Iqbal, I.2    Iqbal, K.3    Oda, Y.4    Tomizawa, K.5    Gong, C.X.6
  • 21
    • 0032498227 scopus 로고    scopus 로고
    • Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
    • Mansuy I. M., Mayford M., Jacob B., Kandel E. R. and Bach M. E. (1998) Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell 92, 39-49.
    • (1998) Cell , vol.92 , pp. 39-49
    • Mansuy, I.M.1    Mayford, M.2    Jacob, B.3    Kandel, E.R.4    Bach, M.E.5
  • 22
    • 0033515643 scopus 로고    scopus 로고
    • Cyclosporine attenuates pressure-overload hypertrophy in mice while enhancing susceptibility to decompensation and heart failure
    • Meguro T., Hong C., Asai K., Takagi G., McKinsey T. A., Olson E. N. and Vatner S. F. (1999) Cyclosporine attenuates pressure-overload hypertrophy in mice while enhancing susceptibility to decompensation and heart failure. Circ. Res. 84, 735-740.
    • (1999) Circ. Res , vol.84 , pp. 735-740
    • Meguro, T.1    Hong, C.2    Asai, K.3    Takagi, G.4    McKinsey, T.A.5    Olson, E.N.6    Vatner, S.F.7
  • 24
    • 0030890757 scopus 로고    scopus 로고
    • Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center
    • Mondragon A., Griffith E. C., Sun L., Xiong F., Armstrong C. and Liu J. O. (1997) Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. Biochemistry 36, 4934-4942.
    • (1997) Biochemistry , vol.36 , pp. 4934-4942
    • Mondragon, A.1    Griffith, E.C.2    Sun, L.3    Xiong, F.4    Armstrong, C.5    Liu, J.O.6
  • 25
    • 0034661450 scopus 로고    scopus 로고
    • Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells
    • Mukerjee N., McGinnis K. M., Park Y. H., Gnegy M. E. and Wang K. K. (2000) Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells. Arch. Biochem. Biophys. 379, 337-343.
    • (2000) Arch. Biochem. Biophys , vol.379 , pp. 337-343
    • Mukerjee, N.1    McGinnis, K.M.2    Park, Y.H.3    Gnegy, M.E.4    Wang, K.K.5
  • 26
    • 0037155226 scopus 로고    scopus 로고
    • Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site
    • Namgaladze D., Hofer H. W. and Ullrich V. (2002) Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site. J. Biol. Chem. 277, 5962-5969.
    • (2002) J. Biol. Chem , vol.277 , pp. 5962-5969
    • Namgaladze, D.1    Hofer, H.W.2    Ullrich, V.3
  • 27
    • 0035078189 scopus 로고    scopus 로고
    • The neuronal endosomal-lysosomal system in Alzheimer's disease
    • Nixon R. A., Mathews P. M. and Cataldo A. M. (2001) The neuronal endosomal-lysosomal system in Alzheimer's disease. J. Alzheimers Dis. 3, 97-107.
    • (2001) J. Alzheimers Dis , vol.3 , pp. 97-107
    • Nixon, R.A.1    Mathews, P.M.2    Cataldo, A.M.3
  • 28
    • 0032510493 scopus 로고    scopus 로고
    • Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
    • de la Pompa J. L., Timmerman L. A., Takimoto H. et al. (1998) Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature 392, 182-186.
    • (1998) Nature , vol.392 , pp. 182-186
    • de la Pompa, J.L.1    Timmerman, L.A.2    Takimoto, H.3
  • 30
    • 0036941275 scopus 로고    scopus 로고
    • Is calcineurin a peroxide-specific sensor in T-lymphocytes?
    • Reiter T. A. and Rusnak F. (2002) Is calcineurin a peroxide-specific sensor in T-lymphocytes? J. Biol. Inorg. Chem. 7, 823-834.
    • (2002) J. Biol. Inorg. Chem , vol.7 , pp. 823-834
    • Reiter, T.A.1    Rusnak, F.2
  • 32
    • 0034708825 scopus 로고    scopus 로고
    • A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling
    • Rothermel B., Vega R. B., Yang J., Wu H., Bassel-Duby R. and Williams R. S. (2000) A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. J. Biol. Chem. 275, 8719-8725.
    • (2000) J. Biol. Chem , vol.275 , pp. 8719-8725
    • Rothermel, B.1    Vega, R.B.2    Yang, J.3    Wu, H.4    Bassel-Duby, R.5    Williams, R.S.6
  • 33
    • 0029761681 scopus 로고    scopus 로고
    • Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4
    • Shibasaki F., Price E. R., Milan D. and McKeon F. (1996) Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4. Nature 382, 370-373.
    • (1996) Nature , vol.382 , pp. 370-373
    • Shibasaki, F.1    Price, E.R.2    Milan, D.3    McKeon, F.4
  • 34
    • 0036548070 scopus 로고    scopus 로고
    • gamma-Secretase, Notch, Abeta and Alzheimer's disease: Where do the presenilins fit in?
    • Sisodia S. S. and St George-Hyslop P. H. (2002) gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in? Nat. Rev. Neurosci. 3, 281-290.
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 281-290
    • Sisodia, S.S.1    St George-Hyslop, P.H.2
  • 35
    • 0034008234 scopus 로고    scopus 로고
    • Modulation of the phosphatase activity of calcineurin by oxidants and antioxidants in vitro
    • Sommer D., Fakata K. L., Swanson S. A. and Stemmer P. M. (2000) Modulation of the phosphatase activity of calcineurin by oxidants and antioxidants in vitro. Eur. J. Biochem. 267, 2312-2322.
    • (2000) Eur. J. Biochem , vol.267 , pp. 2312-2322
    • Sommer, D.1    Fakata, K.L.2    Swanson, S.A.3    Stemmer, P.M.4
  • 36
    • 0032101282 scopus 로고    scopus 로고
    • Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes
    • Sun L., Youn H. D., Loh C., Stolow M., He W. and Liu J. O. (1998) Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes. Immunity 8, 703-708.
    • (1998) Immunity , vol.8 , pp. 703-708
    • Sun, L.1    Youn, H.D.2    Loh, C.3    Stolow, M.4    He, W.5    Liu, J.O.6
  • 38
    • 0029759409 scopus 로고    scopus 로고
    • Superoxide dismutase protects calcineurin from inactivation
    • Wang X., Culotta V. C. and Klee C. B. (1996) Superoxide dismutase protects calcineurin from inactivation. Nature 383, 434-437.
    • (1996) Nature , vol.383 , pp. 434-437
    • Wang, X.1    Culotta, V.C.2    Klee, C.B.3
  • 39
    • 0032498272 scopus 로고    scopus 로고
    • Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin
    • Winder D. G., Mansuy I. M., Osman M., Moallem T. M. and Kandel E. R. (1998) Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin. Cell 92, 25-37.
    • (1998) Cell , vol.92 , pp. 25-37
    • Winder, D.G.1    Mansuy, I.M.2    Osman, M.3    Moallem, T.M.4    Kandel, E.R.5
  • 41
    • 0029896354 scopus 로고    scopus 로고
    • Mechanisms of neuronal degeneration in Alzheimer's disease
    • Yankner B. A. (1996) Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron 16, 921-932.
    • (1996) Neuron , vol.16 , pp. 921-932
    • Yankner, B.A.1
  • 42
    • 0034663805 scopus 로고    scopus 로고
    • Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis
    • Youn H. D., Chatila T. A. and Liu J. O. (2000) Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis. EMBO J. 19, 4323-4331.
    • (2000) EMBO J , vol.19 , pp. 4323-4331
    • Youn, H.D.1    Chatila, T.A.2    Liu, J.O.3
  • 43
    • 0028886436 scopus 로고
    • Evidence that calcineurin accommodates an active site binuclear metal center
    • Yu L., Haddy A. and Rusnak F. (1995) Evidence that calcineurin accommodates an active site binuclear metal center. J. Am. Chem. Soc. 117, 10 147-10 148.
    • (1995) J. Am. Chem. Soc , vol.117
    • Yu, L.1    Haddy, A.2    Rusnak, F.3
  • 44
    • 0030772417 scopus 로고    scopus 로고
    • Spectroscopic and enzymatic characterization of the active site dinuclear metal center of calcineurin: Implications for a mechanistic role
    • Yu L., Golbeck J., Yao J. and Rusnak F. (1997) Spectroscopic and enzymatic characterization of the active site dinuclear metal center of calcineurin: implications for a mechanistic role. Biochemistry 36, 10 727-10 734.
    • (1997) Biochemistry , vol.36
    • Yu, L.1    Golbeck, J.2    Yao, J.3    Rusnak, F.4


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