Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 1, 2004, Pages 247-255

  Veres, Balazs ^a   Radnai, Balazs ^a   Gallyas Jr , Ferenc ^b   Varbiro, Gabor ^a   Berente, Zoltan ^a   Osz, Erzsebet ^a   Sumegi, Balazs ^a,b,c  

^a UNIVERSITY OF PÉCS   (Hungary)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c NONE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYQUINAZOLINE; BACTERIUM LIPOPOLYSACCHARIDE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; POLY(ADP RIBOSE)POLYMERASE 1 INHIBITOR; PROTEIN; PROTEIN KINASE B; PROTEIN P90 RSK; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; INFLAMMATION; KNOCKOUT MOUSE; LIVER; LUNG; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEPTIC SHOCK; SPLEEN; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; HELA CELLS; HUMANS; INFLAMMATION; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHORYLATION; PHOSPHOTRANSFERASES; POLY(ADP-RIBOSE) POLYMERASES; QUINAZOLINES; QUINAZOLINONES; SPLEEN; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3042544529     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.065151     Document Type: Article

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