Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 9, 2011, Pages 2732-2735

  Noël, Romain ^a   Shin, Youseung ^a   Song, Xinyi ^a   He, Yuanjun ^a   Koenig, Marcel ^a   Chen, Weimin ^a   Ling, Yuan Yuan ^a   Lin, Li ^a   Ruiz, Claudia H ^a   Lograsso, Phil ^a   Cameron, Michael D ^a   Duckett, Derek R ^a   Kamenecka, Theodore M ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

c Jun; JNK; Kinase

Indexed keywords

4 (PYRAZOL 3 YL)PYRIDINE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; CONFERENCE PAPER; DRUG SYNTHESIS; MOUSE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ENZYME ACTIVATION; INHIBITORY CONCENTRATION 50; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79955473645     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.104     Document Type: Conference Paper

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