Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis

Arthritis and Rheumatism

Volumn 46, Issue 3, 2002, Pages 818-823

  Han, Zuoning ^a   Chang, Lufen ^a   Yamanishi, Yuji ^a   Karin, Michael ^a   Firestein, Gary S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTHRITIS; ARTICLE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM; SYNOVIOCYTE; WESTERN BLOTTING;

ANIMALS; ARTHRITIS, EXPERIMENTAL; COLLAGENASES; GENE EXPRESSION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JOINTS; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN ISOFORMS; TRANSCRIPTION FACTOR AP-1;

EID: 0036188479     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10104     Document Type: Article

References (15)

1. Rheumatoid arthritis
2. Jun N-terminal kinase in rheumatoid arthritis
3. C-Jun-N-terminal kinase is required for metalloproteinase expression and joint destruction in rheumatoid arthritis
4. AP-1 and NF-κB regulation in rheumatoid arthritis and murine collagen-induced arthritis
5. Integration of the NF-κB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: Divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts
6. Regulation and function of the JNK sub-group of MAP kinases
7. Selective interaction of JNK protein kinase isoforms with transcription factors
8. JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
9. Collagen-induced arthritis in mice: Synergistic effect of E. coli lipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen
10. Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP1) cells
11. Signal transduction and transcription factors in rheumatic diseases
12. Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
13. AP-1 function and regulation
14. Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis
15. JNK is required for effector T-cell function but not for T-cell activation