-
1
-
-
0029019867
-
The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family
-
Apte, S.S., Olsen, B.R., and Murphy, G. (1995). The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J. Biol. Chem. 270, 14313-14318.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14313-14318
-
-
Apte, S.S.1
Olsen, B.R.2
Murphy, G.3
-
2
-
-
0032125517
-
Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death
-
DOI 10.1002/(SICI)1097-4547(19980701)53:1<7::AID-JNR2>3.0.CO;2-F
-
Araki, T., Taniwaki, T., Becerra, S.P., et al. (1998). Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apo-ptotic cell death. J. Neurosci. Res. 53, 7-15. (Pubitemid 28308977)
-
(1998)
Journal of Neuroscience Research
, vol.53
, Issue.1
, pp. 7-15
-
-
Araki, T.1
Taniwaki, T.2
Becerra, S.P.3
Chader, G.J.4
Schwartz, J.P.5
-
3
-
-
0036798747
-
Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents
-
DOI 10.1006/mthe.2002.0702
-
Auricchio, A., Behling, K.C., Maguire, A.M., et al. (2002). Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents. Mol. Ther. 6, 490-494. (Pubitemid 35214870)
-
(2002)
Molecular Therapy
, vol.6
, Issue.4
, pp. 490-494
-
-
Auricchio, A.1
Behling, K.C.2
Maguire, A.M.3
O'Connor, E.E.4
Bennett, J.5
Wilson, J.M.6
Tolentino, M.J.7
-
4
-
-
33746164355
-
EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV
-
DOI 10.1038/sj.gt.3302769, PII 3302769
-
Balaggan, K.S., Binley, K., Esapa, M., et al. (2006). EIAV vector-mediated delivery of endostatin or angiostatin inhibits an-giogenesis and vascular hyperpermeability in experimental CNV. Gene Ther. 13, 1153-1165. (Pubitemid 44084074)
-
(2006)
Gene Therapy
, vol.13
, Issue.15
, pp. 1153-1165
-
-
Balaggan, K.S.1
Binley, K.2
Esapa, M.3
MacLaren, R.E.4
Iqball, S.5
Duran, Y.6
Pearson, R.A.7
Kan, O.8
Barker, S.E.9
Smith, A.J.10
Bainbridge, J.W.B.11
Naylor, S.12
Ali, R.R.13
-
5
-
-
0032796456
-
Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration
-
Bilak, M.M., Corse, A.M., Bilak, S.R., et al. (1999). Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration. J. Neu-ropathol. Exp. Neurol. 58, 719-728. (Pubitemid 29328501)
-
(1999)
Journal of Neuropathology and Experimental Neurology
, vol.58
, Issue.7
, pp. 719-728
-
-
Bilak, M.M.1
Corse, A.M.2
Bilak, S.R.3
Lehar, M.4
Tombran-Tink, J.5
Kuncl, R.W.6
-
6
-
-
33749451356
-
Ranibizumab versus verteporfin for neovascular age-related macular degeneration
-
DOI 10.1056/NEJMoa062655
-
Brown, D.M., Kaiser, P.K., Michels, M., et al.; Anchor Study Group (2006). Ranibizumab versus verteporfin for neovas-cular age-related macular degeneration. N. Engl. J. Med. 355, 1432-1444. (Pubitemid 44511558)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.14
, pp. 1432-1444
-
-
Brown, D.M.1
Kaiser, P.K.2
Michels, M.3
Soubrane, G.4
Heier, J.S.5
Kim, R.Y.6
Sy, J.P.7
Schneider, S.8
-
7
-
-
32944481724
-
Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: Results of a phase I clinical trial
-
DOI 10.1089/hum.2006.17.167
-
Campochiaro, P.A., Nguyen, Q.D., Shah, S.M., et al. (2006). Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: Results of a phase I clinical trial. Hum. Gene Ther. 17, 167-176. (Pubitemid 43262032)
-
(2006)
Human Gene Therapy
, vol.17
, Issue.2
, pp. 167-176
-
-
Campochiaro, P.A.1
Nguyen, Q.D.2
Shah, S.M.3
Klein, M.L.4
Holz, E.5
Frank, R.N.6
Saperstein, D.A.7
Gupta, A.8
Stout, J.T.9
Macko, J.10
DiBartolomeo, R.11
Wei, L.L.12
-
8
-
-
0035014235
-
In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor
-
Cao, W., Tombran-Tink, J., Elias, R., et al. (2001). In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor. Invest. Opthalmol. Vis. Sci. 42, 1642-1652.
-
(2001)
Invest. Opthalmol. Vis. Sci.
, vol.42
, pp. 1642-1652
-
-
Cao, W.1
Tombran-Tink, J.2
Elias, R.3
-
9
-
-
0033538517
-
Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
-
DOI 10.1126/science.285.5425.245
-
Dawson, D.W., Volpert, O.V., Gillis, P., et al. (1999). Pigment epithelium-derived factor: A potent inhibitor of angiogenesis. Science 285, 245-248. (Pubitemid 29329995)
-
(1999)
Science
, vol.285
, Issue.5425
, pp. 245-248
-
-
Dawson, D.W.1
Volpert, O.V.2
Gillis, P.3
Crawford, S.E.4
Xu, H.-J.5
Benedict, W.6
Bouck, N.P.7
-
10
-
-
0029788635
-
Localization of TIMP-3 mRNA expression to the retinal pigment epithelium
-
Della, N.G., Campochiaro, P.A., and Zack, D.J. (1996). Localization of TIMP-3 mRNA expression to the retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 37, 1921-1924. (Pubitemid 26265045)
-
(1996)
Investigative Ophthalmology and Visual Science
, vol.37
, Issue.9
, pp. 1921-1924
-
-
Della, N.G.1
Campochiaro, P.A.2
Zack, D.J.3
-
11
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
DOI 10.1126/science.1110189
-
Edwards, A.O., Ritter, R.R., Abel, K.J., et al. (2005). Complement factor H polymorphism and age-related macular degeneration. Science 308, 421-424. (Pubitemid 40530082)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 421-424
-
-
Edwards, A.O.1
Ritter III, R.2
Abel, K.J.3
Manning, A.4
Panhuysen, C.5
Farrer, L.A.6
-
12
-
-
18444389460
-
Lack of collagen XVIII/endostatin results in eye abnormalities
-
DOI 10.1093/emboj/21.7.1535
-
Fukai, N., Eklund, L., Marneros, A.G., et al. (2002). Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J. 21, 1535-1544. (Pubitemid 34614610)
-
(2002)
EMBO Journal
, vol.21
, Issue.7
, pp. 1535-1544
-
-
Fukai, N.1
Eklund, L.2
Marneros, A.G.3
Oh, S.P.4
Keene, D.R.5
Tamarkin, L.6
Niemela, M.7
Ilves, M.8
Li, E.9
Pihlajaniemi, T.10
Olsen, B.R.11
-
13
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
Gold, B., Merriam, J.E., Zernant, J., et al. (2006). Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat. Genet. 38, 458-462.
-
(2006)
Nat. Genet.
, vol.38
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
-
14
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
DOI 10.1126/science.1110359
-
Haines, J.L., Hauser, M.A., Schmidt, S., et al. (2005). Complement factor H variant increases the risk of age-related macular degeneration. Science 308, 419-421. (Pubitemid 40530081)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
Scott, W.K.4
Olson, L.M.5
Gallins, P.6
Spencer, K.L.7
Shu, Y.K.8
Noureddine, M.9
Gilbert, J.R.10
Schnetz-Boutaud, N.11
Agarwal, A.12
Postel, E.A.13
Pericak-Vance, M.A.14
-
15
-
-
0033334764
-
Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity
-
He, Y., Smith, S.K., Day, K.A., et al. (1999). Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol. Endocrinol. 13, 537-545. (Pubitemid 30636421)
-
(1999)
Molecular Endocrinology
, vol.13
, Issue.4
, pp. 537-545
-
-
He, Y.1
Smith, S.K.2
Day, K.A.3
Clark, D.E.4
Licence, D.R.5
Charnock-Jones, D.S.6
-
16
-
-
0034125023
-
Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: A role of VEGF and possible treatment for SRN in age-related macular degeneration
-
Honda, M., Sakamoto, T., Ishibashi, T., et al. (2000). Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF.flt-1 receptor gene trans-fection: A role of VEGF and possible treatment for SRN in age-related macular degeneration. Gene Ther. 7, 978-985. (Pubitemid 30386663)
-
(2000)
Gene Therapy
, vol.7
, Issue.11
, pp. 978-985
-
-
Honda, M.1
Sakamoto, T.2
Ishibashi, T.3
Inomata, H.4
Ueno, H.5
-
17
-
-
0037318972
-
Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model
-
DOI 10.1038/sj.gt.3301878
-
Igarashi, T., Miyake, K., Kato, K., et al. (2003). Lentivirus-mediated expression of angiostatin efficiently inhibits neo-vascularization in a murine proliferative retinopathy model. Gene Ther. 10, 219-226. (Pubitemid 36204410)
-
(2003)
Gene Therapy
, vol.10
, Issue.3
, pp. 219-226
-
-
Igarashi, T.1
Miyake, K.2
Kato, K.3
Watanabe, A.4
Ishizaki, M.5
Ohara, K.6
Shimada, T.7
-
18
-
-
58849087072
-
EIAV vector-mediated co-delivery of endostatin and angiostatin driven by the RPE-specific VMD2 promoter inhibits choroidal neo-vascularization
-
Kachi, S., Binley, K., Yokoi, K., et al. (2009). EIAV vector-mediated co-delivery of endostatin and angiostatin driven by the RPE-specific VMD2 promoter inhibits choroidal neo-vascularization. Hum. Gene Ther. 20, 31-39.
-
(2009)
Hum. Gene Ther.
, vol.20
, pp. 31-39
-
-
Kachi, S.1
Binley, K.2
Yokoi, K.3
-
19
-
-
0032820720
-
TIMP-3 in Bruch's membrane: Changes during aging and in age-related macular degeneration
-
Kamei, M., and Hollyfield, J.G. (1999). TIMP-3 in Bruch's membrane: Changes during aging and in age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 40, 2367-2375. (Pubitemid 29418393)
-
(1999)
Investigative Ophthalmology and Visual Science
, vol.40
, Issue.10
, pp. 2367-2375
-
-
Kamei, M.1
Hollyfield, J.G.2
-
20
-
-
0030582384
-
Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
-
DOI 10.1006/bbrc.1996.1355
-
Kendall, R.L., Wang, G.L., and Thomas, K.A. (1996). Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem. Biophys. Res. Commun. 226, 324-328. (Pubitemid 26331903)
-
(1996)
Biochemical and Biophysical Research Communications
, vol.226
, Issue.2
, pp. 324-328
-
-
Kendall, R.L.1
Wang, G.2
Thomas, K.A.3
-
21
-
-
0026681119
-
Prevalence of age-related maculopathy: The Beaver Dam Eye Study
-
Klein, R., Klein, B.E., and Linton, K.L. (1992). Prevalence of age-related maculopathy: The Beaver Dam Eye Study. Ophthalmology 99, 933-943.
-
(1992)
Ophthalmology
, vol.99
, pp. 933-943
-
-
Klein, R.1
Klein, B.E.2
Linton, K.L.3
-
22
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
DOI 10.1126/science.1109557
-
Klein, R.J., Zeiss, C., Chew, E.Y., et al. (2005). Complement factor H polymorphism in age-related macular degeneration. Science 308, 385-389. (Pubitemid 40530070)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
23
-
-
0033823756
-
VEGF is an important stimulator in a model of cho-roidal neovascularization
-
Kwak, N., Okamoto, N., Wood, J.M., and Campochiaro, P.A. (2000). VEGF is an important stimulator in a model of cho-roidal neovascularization. Invest. Ophthalmol. Vis. Sci. 41, 3158-3164.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 3158-3164
-
-
Kwak, N.1
Okamoto, N.2
Wood, J.M.3
Campochiaro, P.A.4
-
24
-
-
0034857729
-
Suppression of choroidal neovascularization by adeno-associated virus vector expressing angiostatin
-
Lai, C.-C., Wu, W.-C., Chen, S.-L., et al. (2001). Suppression of choroidal neovascularization by adeno-associated virus vector expressing angiostatin. Invest. Ophthalmol. Vis. Sci. 42, 2401-2407. (Pubitemid 32848872)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.10
, pp. 2401-2407
-
-
Lai, C.-C.1
Wu, W.-C.2
Chen, S.-L.3
Xiao, X.4
Tsai, T.-C.5
Huan, S.-J.6
Chen, T.-L.7
Tsai, R.J.-F.8
Tsao, Y.-P.9
-
25
-
-
25144485909
-
Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys
-
DOI 10.1016/j.ymthe.2005.04.022, PII S1525001605002261
-
Lai, C.M., Shen, W.Y., Brankov, M., et al. (2005). Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys. Mol. Ther. 12, 659-668. (Pubitemid 41350147)
-
(2005)
Molecular Therapy
, vol.12
, Issue.4
, pp. 659-668
-
-
Lai, C.-M.1
Shen, W.-Y.2
Brankov, M.3
Lai, Y.K.Y.4
Barnett, N.L.5
Lee, S.-Y.6
Yeo, I.Y.S.7
Mathur, R.8
Ho, J.E.S.9
Pineda, P.10
Barathi, A.11
Ang, C-.L.12
Constable, I.J.13
Rakoczy, E.P.14
-
26
-
-
0036083592
-
Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy
-
DOI 10.1038/sj.gt.3301695
-
Lai, Y.K., Shen, W.Y., Brankov, M., et al. (2002). Potential long-term inhibition of ocular neovascularization by recombinant adeno-associated virus-mediated secretion gene therapy. Gene Ther. 9, 804-813. (Pubitemid 34679308)
-
(2002)
Gene Therapy
, vol.9
, Issue.12
, pp. 804-813
-
-
Lai, Y.K.Y.1
Shen, W.Y.2
Brankov, M.3
Lai, C.M.4
Constable, I.J.5
Rakoczy, P.E.6
-
27
-
-
54549125880
-
Intraocular route of administration defines humoral immune response and therapeutic potential
-
Li, Q., Miller, R., Han, P.Y., et al. (2008). Intraocular route of administration defines humoral immune response and therapeutic potential. Mol. Ther. 14, 1760-1769.
-
(2008)
Mol. Ther.
, vol.14
, pp. 1760-1769
-
-
Li, Q.1
Miller, R.2
Han, P.Y.3
-
28
-
-
79551652669
-
Inhibition of choroidal neovascularization in a nonhuman primate model by intravitreal administration of an AAV2 vector expressing a novel anti-VEGF molecule
-
Lukason, M., Dufresne, E., Hillard, R., et al. (2011). Inhibition of choroidal neovascularization in a nonhuman primate model by intravitreal administration of an AAV2 vector expressing a novel anti-VEGF molecule. Mol. Ther. 19, 260-265.
-
(2011)
Mol. Ther.
, vol.19
, pp. 260-265
-
-
Lukason, M.1
Dufresne, E.2
Hillard, R.3
-
29
-
-
79551622680
-
Pre-clinical safety evaluation of AAV2-sFLT01: A gene therapy for age-related macular degeneration
-
Maclachlan, T.K., Lukason, M., Collins, M., et al. (2010). Pre-clinical safety evaluation of AAV2-sFLT01: A gene therapy for age-related macular degeneration. Mol. Ther. 19, 326-334.
-
(2010)
Mol. Ther.
, vol.19
, pp. 326-334
-
-
MacLachlan, T.K.1
Lukason, M.2
Collins, M.3
-
30
-
-
77952509760
-
Prolonged blockade of VEGF receptors does not damage retinal photo-receptors or ganglion cells
-
Miki, A., Ueno, S., Wesinger, D.M., et al. (2010). Prolonged blockade of VEGF receptors does not damage retinal photo-receptors or ganglion cells. J. Cell. Physiol. 224, 262-272.
-
(2010)
J. Cell. Physiol.
, vol.224
, pp. 262-272
-
-
Miki, A.1
Ueno, S.2
Wesinger, D.M.3
-
31
-
-
0035404544
-
Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin
-
Mori, K., Ando, A., Gehlbach, P., et al. (2001a). Inhibition of choroidal neovascularization by intravenous injection of ade-noviral vectors expressing secretable endostatin. Am. J. Pathol. 159, 313-320. (Pubitemid 33704216)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.1
, pp. 313-320
-
-
Mori, K.1
Ando, A.2
Gehlbach, P.3
Nesbitt, D.4
Takahashi, K.5
Goldsteen, D.6
Penn, M.7
Chen, C.T.8
Mori, K.9
Melia, M.10
Phipps, S.11
Moffat, D.12
Brazzell, K.13
Liau, G.14
Dixon, K.H.15
Campochiaro, P.A.16
-
32
-
-
0034945843
-
Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization
-
DOI 10.1002/jcp.1114
-
Mori, K., Duh, E., Gehlbach, P., et al. (2001b). Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. J. Cell. Physiol. 188, 253-263. (Pubitemid 32622916)
-
(2001)
Journal of Cellular Physiology
, vol.188
, Issue.2
, pp. 253-263
-
-
Mori, K.1
Duh, E.2
Gehlbach, P.3
Ando, A.4
Takahashi, K.5
Pearlman, J.6
Mori, K.7
Yang, H.S.8
Zack, D.J.9
Ettyreddy, D.10
Brough, D.E.11
Wei, L.L.12
Campochiaro, P.A.13
-
33
-
-
0036297886
-
Regression of ocular neovascularization by increased expression of pigment epithelium-derived factor
-
Mori, K., Gehlbach, P., Ando, A., et al. (2001c). Regression of ocular neovascularization by increased expression of pigment epithelium-derived factor. Invest. Ophthalmol. Vis. Sci. 43, 2428-2434.
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 2428-2434
-
-
Mori, K.1
Gehlbach, P.2
Ando, A.3
-
34
-
-
0036271989
-
AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization
-
Mori, K., Gehlbach, P., Yamamoto, S., et al. (2002). AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 43, 1994-2000. (Pubitemid 34587052)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.6
, pp. 1994-2000
-
-
Mori, K.1
Gehlbach, P.2
Yamamoto, S.3
Duh, E.4
Zack, D.J.5
Li, Q.6
Berns, K.I.7
Raisler, B.J.8
Hauswirth, W.W.9
Campochiaro, P.A.10
-
35
-
-
34547702738
-
Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury
-
DOI 10.2353/ajpath.2007.061237
-
Nishijima, K., Ng, Y.S., Zhong, L., et al. (2007). Vascular endo-thelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury. Am. J. Pathol. 171, 53-67. (Pubitemid 47339226)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.1
, pp. 53-67
-
-
Nishijima, K.1
Ng, Y.-S.2
Zhong, L.3
Bradley, J.4
Schubert, W.5
Jo, N.6
Akita, J.7
Samuelsson, S.J.8
Robinson, G.S.9
Adamis, A.P.10
Shima, D.T.11
-
36
-
-
0036168483
-
Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment
-
Ohno-Matsui, K., Hirose, A., Yamamoto, S., et al. (2002). In-ducible expression of vascular endothelial growth factor in photoreceptors of adult mice causes severe proliferative retinopathy and retinal detachment. Am. J. Pathol. 160, 711-719. (Pubitemid 34160349)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.2
, pp. 711-719
-
-
Ohno-Matsui, K.1
Hirose, A.2
Yamamoto, S.3
Saikia, J.4
Okamoto, N.5
Gehlbach, P.6
Duh, E.J.7
Hackett, S.8
Chang, M.9
Bok, D.10
Zack, D.J.11
Campochiaro, P.A.12
-
37
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
-
DOI 10.1016/0092-8674(94)90200-3
-
O'Reilly, M.S., Holmgren, S., Shing, Y., et al. (1994). Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328. (Pubitemid 24324921)
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 315-328
-
-
O'Reilly, M.S.1
Holmgren, L.2
Shing, Y.3
Chen, C.4
Rosenthal, R.A.5
Moses, M.6
Lane, W.S.7
Cao, Y.8
Helene Sage, E.9
Folkman, J.10
-
38
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
DOI 10.1016/S0092-8674(00)81848-6
-
O'Reilly, M.S., Boehm, T., Shing, Y., et al. (1997). Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell 88, 277-285. (Pubitemid 28015876)
-
(1997)
Cell
, vol.88
, Issue.2
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
Fukai, N.4
Vasios, G.5
Lane, W.S.6
Flynn, E.7
Birkhead, J.R.8
Olsen, B.R.9
Folkman, J.10
-
39
-
-
58149478117
-
Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization
-
Pechan, P., Rubin, H., Lukason, M., et al. (2009). Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization. Gene Ther. 16, 10-16.
-
(2009)
Gene Ther.
, vol.16
, pp. 10-16
-
-
Pechan, P.1
Rubin, H.2
Lukason, M.3
-
40
-
-
0037173042
-
Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization
-
DOI 10.1073/pnas.122247299
-
Raisler, B.J., Berns, K.I., Grant, M.B., et al. (2002). Adeno-associated virus type 2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization. Proc. Natl. Acad. Sci. U.S.A. 99, 8909-8914. (Pubitemid 34693657)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8909-8914
-
-
Raisler, B.J.1
Berns, K.I.2
Grant, M.B.3
Beliaev, D.4
Hauswirth, W.W.5
-
41
-
-
33749445317
-
Ranibizumab for neovascular age-related macular degeneration
-
DOI 10.1056/NEJMoa054481
-
Rosenfeld, P.J., Brown, D.M., Heier, J.S., et al.; Marina Study Group (2006). Ranibizumab for neovascular age-related mac-ular degeneration. N. Engl. J. Med. 355, 1419-1431. (Pubitemid 44511557)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.14
, pp. 1419-1431
-
-
Rosenfeld, P.J.1
Brown, D.M.2
Heier, J.S.3
Boyer, D.S.4
Kaiser, P.K.5
Chung, C.Y.6
Kim, R.Y.7
-
42
-
-
20844432009
-
Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer
-
DOI 10.1002/jgm.586
-
Rota, R., Riccioni, T., Zaccarini, M., et al. (2004). Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer. J. Gene Med. 6, 992-1002. (Pubitemid 40228114)
-
(2004)
Journal of Gene Medicine
, vol.6
, Issue.9
, pp. 992-1002
-
-
Rota, R.1
Riccioni, T.2
Zaccarini, M.3
Lamartina, S.4
Del Gallo, A.5
Fusco, A.6
Kovesdi, I.7
Balestrazzi, E.8
Abeni, D.C.9
Ali, R.R.10
Capogrossi, M.C.11
-
43
-
-
56149103354
-
Endogenous VEGF is required for visual function: Evidence for a survival role on Muller cells and photoreceptors
-
Saint-Geniez, M., Maharaj, A.S.R., Walshe, T.E., et al. (2008). Endogenous VEGF is required for visual function: Evidence for a survival role on Muller cells and photoreceptors. PLoS One 3, e3554.
-
(2008)
PLoS One
, vol.3
-
-
Saint-Geniez, M.1
Maharaj, A.S.R.2
Walshe, T.E.3
-
44
-
-
73249132759
-
An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris
-
Saint-Geniez, M., Kurihara, T., Sekiyama, E., et al. (2009). An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris. Proc. Natl. Acad. Sci. U.S.A. 106, 18751-18756.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 18751-18756
-
-
Saint-Geniez, M.1
Kurihara, T.2
Sekiyama, E.3
-
45
-
-
0037401890
-
R1R2 suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier
-
DOI 10.1002/jcp.10246
-
R1R2 suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J. Cell. Physiol. 195, 241-248. (Pubitemid 36384298)
-
(2003)
Journal of Cellular Physiology
, vol.195
, Issue.2
, pp. 241-248
-
-
Saishin, Y.1
Saishin, Y.2
Takahashi, K.3
Silva, R.L.E.4
Hylton, D.5
Rudge, J.S.6
Wiegand, S.J.7
Campochiaro, P.A.8
-
46
-
-
33646235632
-
Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization
-
DOI 10.1096/fj.05-5046fje
-
Shen, J., Yang, X.R., Xiao, W.H., et al. (2006). Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization. FASEB J. 20, 723-725. (Pubitemid 46671194)
-
(2006)
FASEB Journal
, vol.20
, Issue.6
, pp. 723-725
-
-
Shen, J.1
Yang, X.2
Xiao, W.-H.3
Hackett, S.F.4
Sato, Y.5
Campochiaro, P.A.6
-
47
-
-
0027446940
-
Pigment epithelium-derived factor: Neurotrophic activity and identification as a member of the serine protease inhibitor gene family
-
DOI 10.1073/pnas.90.4.1526
-
Steele, F.R., Chader, G.J., Johnson, L.V., and Tombran-Tink, J. (1993). Pigment epithelium-derived factor: Neurotrophic activity and identification as a member or the serine protease inhibitor gene family. Proc. Natl. Acad. Sci. U.S.A. 90, 1526-1530. (Pubitemid 23058206)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.4
, pp. 1526-1530
-
-
Steele, F.R.1
Chader, G.J.2
Johnson, L.V.3
Tombran-Tink, J.4
-
48
-
-
0036376655
-
Sustained transduction of ocular cells with a bovine immunodeficiency viral vector
-
DOI 10.1089/104303402760128531
-
Takahashi, K., Luo, T., Saishin, Y., et al. (2002). Sustained transduction of ocular cells with a bovine immunodeficiency viral vector. Hum. Gene Ther. 13, 1305-1316. (Pubitemid 35034510)
-
(2002)
Human Gene Therapy
, vol.13
, Issue.11
, pp. 1305-1316
-
-
Takahashi, K.1
Luo, T.2
Saishin, Y.3
Saishin, Y.4
Sung, J.5
Hackett, S.6
Brazzell, R.K.7
Kaleko, M.8
Campochiaro, P.A.9
-
49
-
-
0038661164
-
Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment
-
Takahashi, K., Saishin, Y., Saishin, Y., et al. (2003). Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment. FASEB J. 17, 896-898.
-
(2003)
FASEB J.
, vol.17
, pp. 896-898
-
-
Takahashi, K.1
Saishin, Y.2
Saishin, Y.3
-
50
-
-
0034529765
-
Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells
-
DOI 10.1016/S0002-9394(00)00772-8, PII S0002939400007728
-
Takahashi, T., Nakamura, T., Hayashi, A., et al. (2000). Inhibition of experimental choroidal neovascularization by over-expression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium. Am. J. Ophthalmol. 130, 774-781. (Pubitemid 32000859)
-
(2000)
American Journal of Ophthalmology
, vol.130
, Issue.6
, pp. 774-781
-
-
Takahashi, T.1
Nakamura, T.2
Hayashi, A.3
Kamei, M.4
Nakabayashi, M.5
Okada, A.A.6
Tomita, N.7
Kaneda, Y.8
Tano, Y.9
-
51
-
-
0031768434
-
Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model
-
Tobe, T., Ortega, S., Luna, J.D., et al. (1998). Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model. Am. J. Pathol. 153, 1641-1646. (Pubitemid 28509922)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.5
, pp. 1641-1646
-
-
Tobe, T.1
Ortega, S.2
Luna, J.D.3
Ozaki, H.4
Okamoto, N.5
Derevjanik, N.L.6
Vinores, S.A.7
Basilico, C.8
Campochiaro, P.A.9
-
52
-
-
0025772716
-
PEDF: A pigment epithelium derived factor with potent neuronal differentiating activity
-
Tombran-Tink, J., Chader, G.G., and Johnson, S.V. (1991). PEDF: A pigment epithelium derived factor with potent neuronal differentiating activity. Exp. Eye Res. 53, 411-414.
-
(1991)
Exp. Eye Res.
, vol.53
, pp. 411-414
-
-
Tombran-Tink, J.1
Chader, G.G.2
Johnson, S.V.3
-
53
-
-
49649103814
-
Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels
-
Ueno, S., Pease, M.E., Wersinger, D.M.B., et al. (2008). Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels. J. Cell. Physiol. 217, 13-22.
-
(2008)
J. Cell. Physiol.
, vol.217
, pp. 13-22
-
-
Ueno, S.1
Pease, M.E.2
Wersinger, D.M.B.3
-
54
-
-
9644262535
-
Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis
-
DOI 10.1172/JCI200421152
-
Watanabe, K., Hasegawa, Y., Yamashita, H., et al. (2004). Vaso-hibin as an endothelium-derived negative feedback regulator of angiogenesis. J. Clin. Invest. 114, 898-907. (Pubitemid 39578717)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.7
, pp. 898-907
-
-
Watanabe, K.1
Hasegawa, Y.2
Yamashita, H.3
Shimizu, K.4
Ding, Y.5
Abe, M.6
Ohta, H.7
Imagawa, K.8
Hojo, K.9
Maki, H.10
Sonoda, H.11
Sato, Y.12
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