Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys

Molecular Therapy

Volumn 12, Issue 4, 2005, Pages 659-668

  Lai, Chooi May ^a   Shen, Wei Yong ^a,b   Brankov, Meliha ^a,b   Lai, Yvonne K Y ^a,b   Barnett, Nigel L ^c   Lee, Shu Yen ^d   Yeo, Ian Y S ^d   Mathur, Ranjana ^d   Ho, Joseph E S ^d   Pineda, Paul ^d   Barathi, Amutha ^d   Ang, Chong Lye ^d   Constable, Ian J ^a   Rakoczy, Elizabeth P ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b LIONS EYE INSTITUTE   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d SINGAPORE NATIONAL EYE CENTRE   (Singapore)

Author keywords

Adeno associated virus; Gene therapy; Ocular neovascularization; sFlt 1; VEGF

Indexed keywords

PARVOVIRUS VECTOR; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EYE DISEASE; GENE EXPRESSION; HISTOPATHOLOGY; LASER COAGULATION; LONGITUDINAL STUDY; MONKEY; MOUSE; NONHUMAN; PHOTORECEPTOR; REMISSION; RETINA DISEASE; SUBRETINAL NEOVASCULARIZATION; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CHOROIDAL NEOVASCULARIZATION; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE THERAPY; MACACA FASCICULARIS; MICE; MICE, TRANSGENIC; RETINAL NEOVASCULARIZATION; TRANSDUCTION, GENETIC; TRANSGENES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

ADENO-ASSOCIATED VIRUS; ANIMALIA;

EID: 25144485909     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.04.022     Document Type: Article

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