Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B

Rheumatology

Volumn 50, Issue 5, 2011, Pages 852-861

  Hashiramoto, Akira ^a,b   Murata, Miki ^c   Kawazoe, Takako ^a   Yoshida, Kohsuke ^a   Akiyama, Chieri ^a   Shiozawa, Kazuko ^c   Shiozawa, Shunichi ^a,b,d  

^a KOBE UNIVERSITY   (Japan)

^b KOBE UNIVERSITY HOSPITAL   (Japan)

^c Konan Kakogawa Hospital   (Japan)

^d Global Center of Excellence   (Japan)

Author keywords

Heat shock protein 90; Integrin linked kinase; Mitogen activated protein kinase; Protein kinase B; Synovial cell

Indexed keywords

ALPHA PARVIN; CASPASE; CELL PROTEIN; F ACTIN; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN LINKED KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PARTICULARLY INTERESTING NEW CYSTEINE HISTIDINE PROTEIN; PROTEIN BCL 2; PROTEIN KINASE B; RAC PROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL PROTECTION; CELL STRUCTURE; CELL ULTRASTRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME STABILITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; WESTERN BLOTTING;

APOPTOSIS; ARTHRITIS, RHEUMATOID; BENZOQUINONES; CELLS, CULTURED; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE;

EID: 79955135339     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keq385     Document Type: Article

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