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Volumn 36, Issue 1, 2010, Pages 181-192

ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB

Author keywords

Akt; CREB; ICAM 3; Invasion; Migration; MMP

Indexed keywords

BETA ACTIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GELATINASE A; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 3; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P53;

EID: 74549132674     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo-00000489     Document Type: Article
Times cited : (76)

References (47)
  • 1
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • Friedl P and Wolf K: Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3: 362-374, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 2
    • 52149088558 scopus 로고    scopus 로고
    • Molecular mechanisms of metastasis
    • Weber GF: Molecular mechanisms of metastasis. Cancer Lett 270: 181-190, 2008.
    • (2008) Cancer Lett , vol.270 , pp. 181-190
    • Weber, G.F.1
  • 3
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: Building a framework
    • Gupta GP and Massague J: Cancer metastasis: building a framework. Cell 127: 679-695, 2006.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 4
    • 33750890673 scopus 로고    scopus 로고
    • Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3-Kinase/Akt/NF-kB signal transduction pathway
    • Cheng JC, Chou CH, Kuo ML and Hsieh CY: Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3-Kinase/Akt/NF-kB signal transduction pathway. Oncogene 25: 7009-7018, 2006.
    • (2006) Oncogene , vol.25 , pp. 7009-7018
    • Cheng, J.C.1    Chou, C.H.2    Kuo, M.L.3    Hsieh, C.Y.4
  • 5
    • 26044455880 scopus 로고    scopus 로고
    • Silibinin inhibits cell invasion through inactivation of both PI3-Kinase/Akt and MAPK signalling pathways
    • Chen PN, Hsieh YS, Chiou HL and Chu SC: Silibinin inhibits cell invasion through inactivation of both PI3-Kinase/Akt and MAPK signalling pathways. Chem Biol Interact 156: 141-150, 2005.
    • (2005) Chem Biol Interact , vol.156 , pp. 141-150
    • Chen, P.N.1    Hsieh, Y.S.2    Chiou, H.L.3    Chu, S.C.4
  • 6
    • 0029868605 scopus 로고    scopus 로고
    • The neural cell adhesion molecule NCAM in multiple myeloma
    • Kaiser U, Auerbach B and Oldenburg M: The neural cell adhesion molecule NCAM in multiple myeloma. Leuk Lymphoma 20: 389-395, 1996.
    • (1996) Leuk Lymphoma , vol.20 , pp. 389-395
    • Kaiser, U.1    Auerbach, B.2    Oldenburg, M.3
  • 7
    • 2942541207 scopus 로고    scopus 로고
    • Laboratory variables and stratification of metastatic colorectal cancer patients: Recommendations for therapeutic trials and for clinical practice guidelines
    • Watine J and Friedberg B: Laboratory variables and stratification of metastatic colorectal cancer patients: recommendations for therapeutic trials and for clinical practice guidelines. Clin Chim Acta 345: 1-15, 2004.
    • (2004) Clin Chim Acta , vol.345 , pp. 1-15
    • Watine, J.1    Friedberg, B.2
  • 8
    • 0023874285 scopus 로고    scopus 로고
    • ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM
    • Simmons D, Makgoba MW and Seed B: ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM. Nature 331: 624-627, 1998.
    • (1998) Nature , vol.331 , pp. 624-627
    • Simmons, D.1    Makgoba, M.W.2    Seed, B.3
  • 9
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer TA: Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314, 1994.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 11
    • 40749089873 scopus 로고    scopus 로고
    • Importance of molecular studies on major blood groups-intercellular adhesion molecule-4, a blood group antigen involved in multiple cellular interactions
    • Toivanen A, Ihanus E, Mattila M, Lutz HU and Gahmberg CG: Importance of molecular studies on major blood groups-intercellular adhesion molecule-4, a blood group antigen involved in multiple cellular interactions. Biochim Biophys Acta 1780: 456-466, 2008.
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 456-466
    • Toivanen, A.1    Ihanus, E.2    Mattila, M.3    Lutz, H.U.4    Gahmberg, C.G.5
  • 12
    • 41549101916 scopus 로고    scopus 로고
    • ICAM-5 - a novel two-facetted adhesion molecule in the mammalian brain
    • Gahmberg CG, Tian L, Ning L and Nyman-Huttunen H: ICAM-5 - a novel two-facetted adhesion molecule in the mammalian brain. Immunol Lett 117: 131-135, 2008.
    • (2008) Immunol Lett , vol.117 , pp. 131-135
    • Gahmberg, C.G.1    Tian, L.2    Ning, L.3    Nyman-Huttunen, H.4
  • 13
    • 0036481121 scopus 로고    scopus 로고
    • C-type lectin receptors on dendritic cells and Langerhans cells
    • Figdor CG, van Kooyk Y and Adema GJ: C-type lectin receptors on dendritic cells and Langerhans cells. Nat Rev Immunol 2: 77-84, 2002.
    • (2002) Nat Rev Immunol , vol.2 , pp. 77-84
    • Figdor, C.G.1    van Kooyk, Y.2    Adema, G.J.3
  • 14
    • 0034304945 scopus 로고    scopus 로고
    • DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking
    • Geijtenbeek TBH, Krooshoop DJEB, Bleijs DA, et al: DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking. Nat Immunol 1: 353-357, 2000
    • (2000) Nat Immunol , vol.1 , pp. 353-357
    • Geijtenbeek, T.B.H.1    Krooshoop, D.J.E.B.2    Bleijs, D.A.3
  • 15
    • 0036580775 scopus 로고    scopus 로고
    • Expression of intercellular adhesion molecule-1 and prognosis in colorectal cancer
    • Maeda K, Kang SM, Sawada T, et al: Expression of intercellular adhesion molecule-1 and prognosis in colorectal cancer. Oncol Rep 9: 511-514, 2002.
    • (2002) Oncol Rep , vol.9 , pp. 511-514
    • Maeda, K.1    Kang, S.M.2    Sawada, T.3
  • 16
    • 23644462838 scopus 로고    scopus 로고
    • Up regulation of ICAM-1 gene expression inhibits tumour growth and liver metastasis in colorectal carcinoma
    • Tachimori A, Yamada N, Sakate Y, et al: Up regulation of ICAM-1 gene expression inhibits tumour growth and liver metastasis in colorectal carcinoma. Eur J Cancer 41: 1802-1810, 2005.
    • (2005) Eur J Cancer , vol.41 , pp. 1802-1810
    • Tachimori, A.1    Yamada, N.2    Sakate, Y.3
  • 17
    • 0033376770 scopus 로고    scopus 로고
    • Cell adhesion molecules in the development and progression of malignant melanoma
    • Johnson JP: Cell adhesion molecules in the development and progression of malignant melanoma. Cancer Metastasis Rev 18: 345-357, 1999.
    • (1999) Cancer Metastasis Rev , vol.18 , pp. 345-357
    • Johnson, J.P.1
  • 18
    • 33847216148 scopus 로고    scopus 로고
    • Endothelial cell adhesion molecules and cancer progression
    • Kobayashi H, Boelte KC and Lin PC: Endothelial cell adhesion molecules and cancer progression. Curr Med Chem 14: 377-386, 2007.
    • (2007) Curr Med Chem , vol.14 , pp. 377-386
    • Kobayashi, H.1    Boelte, K.C.2    Lin, P.C.3
  • 19
    • 0030960689 scopus 로고    scopus 로고
    • Clinical significance of alpha(v)beta3 integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions
    • Natali PG, Hamby CV, Felding-Habermann B, et al: Clinical significance of alpha(v)beta3 integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions. Cancer Res 57: 1554-1560, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1554-1560
    • Natali, P.G.1    Hamby, C.V.2    Felding-Habermann, B.3
  • 20
    • 4944227529 scopus 로고    scopus 로고
    • Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: Molecular and functional study of novel alpha-methylene-gamma- butyrolactone derivatives
    • Huang WC, Chan ST, Yang TL, Tzeng CC and Chen CC: Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel alpha-methylene-gamma- butyrolactone derivatives. Carcinogenesis 25: 1925-1934, 2004.
    • (2004) Carcinogenesis , vol.25 , pp. 1925-1934
    • Huang, W.C.1    Chan, S.T.2    Yang, T.L.3    Tzeng, C.C.4    Chen, C.C.5
  • 21
    • 19844379129 scopus 로고    scopus 로고
    • Role of ICAM1 in invasion of human breast cancer cells
    • Rosette C, Roth RB, Oeth P, et al: Role of ICAM1 in invasion of human breast cancer cells. Carcinogenesis 26: 943-950, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 943-950
    • Rosette, C.1    Roth, R.B.2    Oeth, P.3
  • 23
    • 0030049817 scopus 로고    scopus 로고
    • Intercellular adhesion molecules (ICAMs) 2 and 3 are frequently expressed in B cell chronic lymphocytic leukemia
    • Molica S, Dattilo A, Mannella A and Levato D: Intercellular adhesion molecules (ICAMs) 2 and 3 are frequently expressed in B cell chronic lymphocytic leukemia. Leukemia 10: 907-908, 1996.
    • (1996) Leukemia , vol.10 , pp. 907-908
    • Molica, S.1    Dattilo, A.2    Mannella, A.3    Levato, D.4
  • 24
    • 38949202402 scopus 로고    scopus 로고
    • Cell adhesion molecules: Potential therapeutic & diagnostic implications
    • Mousa SA: Cell adhesion molecules: potential therapeutic & diagnostic implications. Mol Biotechnol 38: 33-40, 2008.
    • (2008) Mol Biotechnol , vol.38 , pp. 33-40
    • Mousa, S.A.1
  • 25
    • 25444498096 scopus 로고    scopus 로고
    • Increased expression of ICAM-3 is associated with radiation resistance in cervical cancer
    • Chung YM, Kim BG, Park CS, et al: Increased expression of ICAM-3 is associated with radiation resistance in cervical cancer. Int J Cancer 117: 194-201, 2005.
    • (2005) Int J Cancer , vol.117 , pp. 194-201
    • Chung, Y.M.1    Kim, B.G.2    Park, C.S.3
  • 26
    • 33745344607 scopus 로고    scopus 로고
    • ICAM-3-induced cancer cell proliferation through the PI3K/Akt pathway
    • Kim YG, Kim MJ, Lim JS, Lee MS, Kim JS and Yoo YD: ICAM-3-induced cancer cell proliferation through the PI3K/Akt pathway. Cancer Lett 239: 103-110, 2006.
    • (2006) Cancer Lett , vol.239 , pp. 103-110
    • Kim, Y.G.1    Kim, M.J.2    Lim, J.S.3    Lee, M.S.4    Kim, J.S.5    Yoo, Y.D.6
  • 27
    • 33744903663 scopus 로고    scopus 로고
    • Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1
    • Bae IH, Park MJ, Yoon SH, et al: Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1. Cancer Res 66: 4991-4995, 2006.
    • (2006) Cancer Res , vol.66 , pp. 4991-4995
    • Bae, I.H.1    Park, M.J.2    Yoon, S.H.3
  • 28
    • 40949160953 scopus 로고    scopus 로고
    • Combination of PTEN and gamma-ionizing radiation enhances cell death and G(2)/M arrest through regulation of AKT activity and p21 induction in non-small-cell lung cancer cells
    • Park JK, Jung HY, Park SH, et al: Combination of PTEN and gamma-ionizing radiation enhances cell death and G(2)/M arrest through regulation of AKT activity and p21 induction in non-small-cell lung cancer cells. Int J Radiat Oncol Biol Phys 70: 1552-1560, 2008.
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 1552-1560
    • Park, J.K.1    Jung, H.Y.2    Park, S.H.3
  • 29
    • 38849178686 scopus 로고    scopus 로고
    • Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1
    • Weng CJ, Chau CF, Hsieh YS, Yang SF and Yen GC: Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1. Carcinogenesis 29: 147-156, 2008.
    • (2008) Carcinogenesis , vol.29 , pp. 147-156
    • Weng, C.J.1    Chau, C.F.2    Hsieh, Y.S.3    Yang, S.F.4    Yen, G.C.5
  • 30
    • 33645287685 scopus 로고    scopus 로고
    • Akt/PKB signaling in cancer: A function in cell motility and invasion
    • Yoeli-Lerner M and Toker A: Akt/PKB signaling in cancer: a function in cell motility and invasion. Cell Cycle 5: 603-605, 2006.
    • (2006) Cell Cycle , vol.5 , pp. 603-605
    • Yoeli-Lerner, M.1    Toker, A.2
  • 31
    • 7744229935 scopus 로고    scopus 로고
    • Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: Involvement of invasive potential
    • Chung TW, Lee YC and Kim CH: Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential. FASEB J 18: 1123-1125, 2004.
    • (2004) FASEB J , vol.18 , pp. 1123-1125
    • Chung, T.W.1    Lee, Y.C.2    Kim, C.H.3
  • 32
    • 34948853273 scopus 로고    scopus 로고
    • A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier
    • Kargozaran H, Yuan SY, Breslin JW, et al: A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier. Clin Exp Metastasis 24: 495-502, 2007.
    • (2007) Clin Exp Metastasis , vol.24 , pp. 495-502
    • Kargozaran, H.1    Yuan, S.Y.2    Breslin, J.W.3
  • 33
    • 17944369447 scopus 로고    scopus 로고
    • The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups
    • Levin JI, Chen J, Du M, et al: The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups. Bioorg Med Chem Lett 11: 2189-2192, 2001.
    • (2001) Bioorg Med Chem Lett , vol.11 , pp. 2189-2192
    • Levin, J.I.1    Chen, J.2    Du, M.3
  • 35
    • 0032484019 scopus 로고    scopus 로고
    • CREB is a regulatory target for the protein kinase Akt/PKB
    • Du K and Montminy M: CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem 273: 32377-32379, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 32377-32379
    • Du, K.1    Montminy, M.2
  • 36
    • 0033777783 scopus 로고    scopus 로고
    • Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor family
    • Jean D and Bar-Eli M: Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor family. Mol Cell Biochem 212: 19-28, 2000.
    • (2000) Mol Cell Biochem , vol.212 , pp. 19-28
    • Jean, D.1    Bar-Eli, M.2
  • 37
    • 16544364483 scopus 로고    scopus 로고
    • Dominant-negative CREB inhibits heparanase functionality and melanoma cell invasion
    • Aucoin R, Reiland J, Roy M and Marchetti D: Dominant-negative CREB inhibits heparanase functionality and melanoma cell invasion. J Cell Biochem 93: 215-223, 2004.
    • (2004) J Cell Biochem , vol.93 , pp. 215-223
    • Aucoin, R.1    Reiland, J.2    Roy, M.3    Marchetti, D.4
  • 38
    • 33845348208 scopus 로고    scopus 로고
    • p53 attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts
    • Moskovits N, Kalinkovich A, Bar J, Lapidot T and Oren M: p53 attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts. Cancer Res 66: 10671-10676, 2006.
    • (2006) Cancer Res , vol.66 , pp. 10671-10676
    • Moskovits, N.1    Kalinkovich, A.2    Bar, J.3    Lapidot, T.4    Oren, M.5
  • 39
    • 34347382959 scopus 로고    scopus 로고
    • Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices
    • Gadea G, de Toledo M, Anguille C and Roux P: Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. J Cell Biol 178: 23-30, 2007.
    • (2007) J Cell Biol , vol.178 , pp. 23-30
    • Gadea, G.1    de Toledo, M.2    Anguille, C.3    Roux, P.4
  • 40
    • 0033556443 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: Differential involvement of focal adhesion kinase and p130Cas
    • Tamura M, Gu J, Takino T and Yamada KM: Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. Cancer Res 59: 442-449, 1999.
    • (1999) Cancer Res , vol.59 , pp. 442-449
    • Tamura, M.1    Gu, J.2    Takino, T.3    Yamada, K.M.4
  • 41
    • 39149122846 scopus 로고    scopus 로고
    • An intracellular signal pathway that regulates cancer cell adhesion in response to extracellular forces
    • Basson MD: An intracellular signal pathway that regulates cancer cell adhesion in response to extracellular forces. Cancer Res 68: 2-4, 2008.
    • (2008) Cancer Res , vol.68 , pp. 2-4
    • Basson, M.D.1
  • 42
    • 3543023861 scopus 로고    scopus 로고
    • Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway
    • Xia H, Nho RS, Kahm J, Kleidon J and Henke CA: Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway. J Biol Chem 279: 33024-33034, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 33024-33034
    • Xia, H.1    Nho, R.S.2    Kahm, J.3    Kleidon, J.4    Henke, C.A.5
  • 44
    • 3042604489 scopus 로고    scopus 로고
    • Modulation of FAK, Akt, and p53 by stress release of the fibroblast-populated collagen matrix1, 2
    • Carlson M, Longaker J and Thompson JS: Modulation of FAK, Akt, and p53 by stress release of the fibroblast-populated collagen matrix1, 2. J Surg Res 120: 171-177, 2004.
    • (2004) J Surg Res , vol.120 , pp. 171-177
    • Carlson, M.1    Longaker, J.2    Thompson, J.S.3
  • 45
    • 33748995139 scopus 로고    scopus 로고
    • Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways
    • Park C-M, Park M-J, Kwak H-J, et al: Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways. Cancer Res 66: 8511-8519, 2006.
    • (2006) Cancer Res , vol.66 , pp. 8511-8519
    • Park, C.-M.1    Park, M.-J.2    Kwak, H.-J.3
  • 46
    • 0242551706 scopus 로고    scopus 로고
    • Ionizing radiation modulates expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro
    • Beinke C, van Beuningen D and Cordes N: Ionizing radiation modulates expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro. Int J Radiat Biol Phys 79: 721-731, 2003.
    • (2003) Int J Radiat Biol Phys , vol.79 , pp. 721-731
    • Beinke, C.1    van Beuningen, D.2    Cordes, N.3


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