Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy

Journal of Controlled Release

Volumn 150, Issue 3, 2011, Pages 256-265

  Kigasawa, Kaoru ^a   Kajimoto, Kazuaki ^a   Nakamura, Takashi ^a   Hama, Susumu ^b   Kanamura, Kiyoshi ^c   Harashima, Hideyoshi ^a   Kogure, Kentaro ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c TTI Ellebeau Inc   (Japan)

Author keywords

Cancer immunotherapy; CpG ODN; Iontophoresis; Transdermal drug delivery

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTIGEN PRESENTING CELLS; CANCER IMMUNOTHERAPY; CPG-ODN; CYTOKINES; GUANOSINES; HYDROPHILIC MACROMOLECULES; IMMUNE RESPONSE; IONTOPHORESIS; IONTOPHORETIC DELIVERY; LYMPH NODE; OLIGODEOXYNUCLEOTIDES; PROINFLAMMATORY; SMALL INTERFERING RNA (SIRNA); TRANSDERMAL; TRANSDERMAL DELIVERY; TRANSDERMAL DRUG DELIVERY; TUMOR AREAS;

DERMATOLOGY; DRUG DELIVERY; ELECTROPHORESIS; ELECTROTHERAPEUTICS; IMMUNOLOGY; ONCOLOGY; RNA;

DISEASES;

CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; IMMUNE RESPONSE; IONTOPHORESIS; MALE; MELANOMA; MOUSE; NON INVASIVE PROCEDURE; NONHUMAN; PRIORITY JOURNAL; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, CUTANEOUS; ANIMALS; CYTOKINES; IMMUNOTHERAPY; IONTOPHORESIS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, HAIRLESS; OLIGODEOXYRIBONUCLEOTIDES; SKIN;

EID: 79955059525     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.01.018     Document Type: Article

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