Staphylococcal toxins and protein A differentially induce cytotoxicity and release of tumor necrosis factor-α from human keratinocytes

Journal of Investigative Dermatology

Volumn 107, Issue 4, 1996, Pages 603-609

  Ezepchuk, Yuri V ^a,b   Leung, Donald Y M ^a   Middleton, Marjorie H ^c   Bina, Paul ^d   Reiser, Raoul ^d   Norris, David A ^c,e  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Toxin Technology   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

Atopic dermatitis; Bacterial pathogenicity; Cytokines; Psoriasis

Indexed keywords

BACTERIAL TOXIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PSORIASIS; STAPHYLOCOCCUS AUREUS;

EID: 0029797332     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12583377     Document Type: Article

References (39)

1. Baker BS, Bokth S, Powles A, Garioch JJ, Lewis H, Valdimarisson H, Fry L: Group A streptococcal antigen-specific T lymphocytes in guttate psoriatic lesions. Br J Dermatol 128:493-499, 1993
2. Bhakdi S, Muhly M, Koroni S, Hugo F: Release of interleukin-1β associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes. Infect Immun 57:3512-3519, 1989
3. Bhakdi S, Tranum-Jensen J: Alpha-toxin of Staphylococcus aureus. Microbiol Rev 55:733-751, 1991
4. Bradford MM: A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
5. Catalona WJ, Ratliff TL, McCool RE: Gamma-interferon induced by S. aureus protein A augments natural killing and ADCC. Nature 291:77-79, 1981
6. Cheung AL, Bayer AS, Peters J, Ward JI: Analysis by gel electrophoresis, Western blot, and peptide mapping of protein A heterogeneity in Staphylococcus aureus strains. Infect Immun 55:843-847, 1987
7. Duke RC, Witter RZ, Nash PB, Young JD-E, Ojcius DM: Cytolysis mediated by ionophores and pore-forming agents: role of intracellular calcium in apoptosis. FASEB J 8:237-346, 1994
8. Ealey PA, Yateman ME, Holt SJ, Marshall NJ: ESTA: a bioassay system for the determination of the potencies of hormones and antibodies which mimic their action. J Mol Endocrinol 1:R1-4, 1988
9. Ezepchuk YV, Bucharova TV, Bejelbaeva ML: Interaction of staphylococcal alpha-toxin with biomembranes. Mol Genet Microbiol Virol 6:89-94, 1990
10. Freer JH, Arbuthnott JP: Toxins of Staphylococcus aureus. Pharmacol Ther 19:55-106, 1983
11. Herman A, Kappler JW, Marrack P, Pullen AM: Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol 9:745-772, 1991
12. Kashihara-Sawami M, Norris DA: The state of differentiation of cultured human keratinocytes determines the level of intercellular adhesion molecule-1 (ICAM-1) expression induced by gamma interferon. J Invest Dermatol 98:741-747, 1992
13. Kay HD, Bonnard GD, West WH, Herberman RB: A functional comparison of human Fc-receptor-bearing lymphocytes active in natural cytotoxicity and antibody-dependent cellular cytotoxicity. J Immunol 118:2058-2066, 1977
14. Koeck A, Schwarz T, Kirnbauer R, Urbanski A, Perry P, Ansel JC, Luger TA: Human keratinocytes are a source for TNF-α: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med 172:1609-1614, 1990
15. Kramer SM, Carver M: Serum-free in vitro bio-assay for the detection of tumor necrosis factor. J Immunol Methods 93:201-205, 1986
16. Krasilnicov OV, Sabirov RZ: Ion transport through channels formed in lipid bilayers by Staphylococcus aureus alpha-toxin. Gen Physiol Biophys 8:213-222, 1989
17. Kupper TS: Immune and inflammatory processes in cutaneous tissues: mechanism and speculations. J Clin Invest 86:1783-1789, 1990
18. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685, 1970
19. Lee PK, Vercellotti GM, Deringer JR, Schlievert PM: Effects of staphylococcal toxic shock syndrome toxin 1 on aortic endothelial cells. J Infect Dis 164:711-719, 1991
20. Leung DYM, Gately M, Trumble A, Ferguson-Darnell B, Schlievert PM, Picker LJ: Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J Exp Med 181:747-753, 1995a
21. Leung DYM, Harbeck R, Bina P, Reiser RF, Yang E, Norris DA, Hanifin JM, Sampson HA: Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 92:1374-1380, 1993a
22. Leung DYM, Travers JB, Giorno R, Norris DA, Kazemi LV, Trumble AE, Kotb M, Schlievert PM: Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis. J Clin Invest 96:2106-2112, 1995b
23. Leung DYM, Travers JB, Norris DA: Role of superantigens in human skin disease. J Invest Dermatol 105:375-425, 1995c
24. Leung DYM, Walsh P, Giorno R, Norris DA: A potential role for superantigens in the pathogenesis of psoriasis. J Invest Dermatol 100:225-228, 1993b
25. Lewis HM, Baker BS, Bokth S, Powles AV, Garioch JJ, Valdimarsson H, Fry L: Restricted T-cell receptor V beta gene usage in the skin of patients with guttate and chronic plaque psoriasis. Br J Dermatol 129:514-320, 1993
26. Lopez-Moratalla N, Lopez-Zabalza MJ, Subira ML, Borras-Cuesta F, Perez-Mediavilla LA, Santiago E: Immunomodulation induced by synthetic peptides derived from Staphylococcus aureus protein A. Biochim Biophys Acta 1221:153-158, 1994
27. MacNeil S, Dawson RA, Crocker G, Tucker WFG, Bittiner B, Singlton JG, Hunter T, Tierney DF: Antiproliferative effects on keratinocytes of a range of clinically used drugs with calmodulin antagonist activity. Br J Dermatol 128:143-150, 1993
28. McKenzie RC, Sauder DN: The role of keratinocyte cytokines in inflammation and immunity. J Invest Dermatol 95:105S-107S, 1990
29. Nickoloff BJ, Karabin GD, Barker JN, Griffiths CE, Sarma V, Mitra RS, Elder JT, Kunkel SL, Dixit VM: Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis. Am J Pathol 138:129-140, 1991
30. Ouchterlony O: Immunological analysis of diphtheria antigens by gel diffusion method. Acta Med Scand 138:76-79, 1950
31. Patel PC, Stefanescu-Soare I, Menezes J: Staphylococcal protein A enhances NK activity against lymphoid tumor cell lines. Int J Cancer 28:277-282, 1981
32. Robbins R, Gould S, Bergdoll M: Detecting the enterotoxigenicity of S. aureus strains. Appl Microbiol 28:946-950, 1974
33. Sakurada J, Zhijun L, Seki K, Murai M, Usui A, Morihigashi M, Jitsukawa H, Seong HK, Mutou M, Masuda S: Biochemical and genetic heterogeneity of staphylococcal protein A. FEMS Microbiol Lett 119:59-64, 1994
34. Shuttleworth HL, Duggleby CJ, Jones SA, Atkinson T, Minton NP: Nucleotide sequence analysis of the gene for protein A from S. aureus Cowan I (NCTC8530) and its enhanced expression in E. coli. Gene 58:283-295, 1987
35. B 3-restricted unconventional bacterial antigen. J Immunol 151:5840-5855, 1993
36. Suttorp N, Hessz T, Seeger W, Wilke A, Koob R, Lutz F, Drenckhahn D: Bacterial toxins and endothelial permeability for water and albumin in vitro. Am J Physiol 255:C368-C369, 1988
37. Tokura Y, Yagi J, O'Malley M, Lewis JM, Takigawa M, Edelson RL, Tigelaar RE: Superantigenic staphylococcal exotoxins induced T-cell proliferation in the presence of Langerhans cells or class II-bearing keratinocytes and stimulate keratinocytes to produce T-cell-activating cytokines. J Invest Dermatol 102:31-38, 1994
38. Walev I, Martin E, Jonas D, Mohamadzadeh M, Muller-Klieser W, Kunz L, Bhakdi S: Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions. Infect Immun 61:4972-4979, 1993
39. Watanabe M, Kato I: Purification and some properties of a lethal toxic fragment of staphylococcal α-toxin by tryptic digestion. Biochim Biophys Acta 535:388-400, 1978