Changes in immune responses to antigen applied to tape-stripped skin with CpG-oligodeoxynucleotide in mice

Journal of Controlled Release

Volumn 108, Issue 2-3, 2005, Pages 294-305

  Inoue, Joe ^a   Yotsumoto, Satoshi ^a   Sakamoto, Takatoshi ^a   Tsuchiya, Seishi ^a   Aramaki, Yukihiko ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Atopic dermatitis; CpG ODN; Th1 Th2 balance; Transdermal administration

Indexed keywords

CYTOLOGY; IMMUNOLOGY; MATHEMATICAL MODELS; SKIN;

ATOPIC DERMATISIS; CPG-ODN; TH1/TH2 BALANCE; TRANSDERMAL ADMINISTRATION;

ANTIGENS;

ANTIBODY; ANTIGEN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G2A; INTERLEUKIN 12; INTERLEUKIN 4; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE; OVALBUMIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; ARTICLE; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG PENETRATION; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; LYMPH NODE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN PENETRATION; TH1 CELL; TH2 CELL; TRANSDERMAL PATCH;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, TOPICAL; ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; ANTIGENS; CYTOKINES; DERMATITIS, ATOPIC; MALE; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDES; OVALBUMIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN ABSORPTION; SPLEEN; TH1 CELLS; TH2 CELLS;

EID: 27744509718     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.08.014     Document Type: Article

References (37)

1. H. Nakamura, M. Aoki, K. Tamai, M. Oishi, T. Ogihara, Y. Kaneda, and R. Morishita Prevention and regression of atopic dermatitis by ointment containing NF-kB decoy oligodeoxynucleotides in NC/Nga atopic mouse model Gene Ther. 9 2002 1221 1229
2. D.Y. Leung, M. Boguniewicz, M.D. Howell, I. Nomura, and Q.A. Hamid New insights into atopic dermatitis J. Clin. Invest. 113 2004 651 657
3. T.R. Mosmann, and R.L. Coffman TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Annu. Rev. Immunol. 7 1989 145 173
4. D.F. Fiorentino, M.W. Bond, and T.R. Mosmann Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J. Exp. Med. 170 1989 2081 2095
5. M. Grewe, C.A. Bruijnzeel-Koomen, E. Schopf, T. Thepen, A.G. Langeveld-Wildschut, T. Ruzicka, and J. Krutmann A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis Immunol. Today 19 1998 359 361
6. J.M. Spergel, E. Mizoguchi, H. Oettgen, A.K. Bhan, and R.S. Geha Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis J. Clin. Invest. 103 1999 1103 1111
7. C. Vestergaard, H. Yoneyama, M. Murai, K. Nakamura, K. Tamaki, Y. Terashima, T. Imai, O. Yoshie, T. Irimura, H. Mizutani, and K. Matsushima Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions J. Clin. Invest. 104 1999 1097 1105
8. T.M. Tuttle, C.W. McCrady, T.H. Inge, M. Salour, and H.D. Bear Gamma-interferon plays a key role in T-cell-induced tumor regression Cancer Res. 53 1993 833 839
9. A.M. Krieg CpG motifs in bacterial DNA and their immune effects Annu. Rev. Immunol. 20 2002 709 760
10. S. Agrawal, and E.R. Kandimalla Modulation of toll-like receptor 9 responses through synthetic immunostimulatory motifs of DNA Ann. N.Y. Acad. Sci. 1002 2003 30 42
11. H. Hemmi, T. Kaisho, K. Takeda, and S. Akira The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets J. Immunol. 170 2003 3059 3064
12. B. Spies, H. Hochrein, M. Vabulas, K. Huster, D.H. Busch, F. Schmitz, A. Heit, and H. Wagner Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice J. Immunol. 171 2003 5908 5912
13. A.K. Yi, J.H. Chace, J.S. Cowdery, and A.M. Krieg IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides J. Immunol. 156 1996 558 564
14. S. Sivori, M. Falco, M. Della Chiesa, S. Carlomagno, M. Vitale, L. Moretta, and A. Moretta CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells Proc. Natl. Acad. Sci. U. S. A. 101 2004 10116 10121
15. D.M. Klinman, D. Currie, I. Gursel, and D. Verthelyi Use of CpG oligodeoxynucleotides as immune adjuvants Immunol. Rev. 199 2004 201 216
16. A.S. Beignon, J.P. Briand, S. Muller, and C.D. Partidos Immunization onto bare skin with synthetic peptides: immunomodulation with a CpG-containing oligodeoxynucleotide and effective priming of influenza virus-specific CD4+ T cells Immunology 105 2002 204 212
17. S.K. Klimuk, H.M. Najar, S.C. Semple, S. Aslanian, and J.P. Dutz Epicutaneous application of CpG oligodeoxynucleotides with peptide or protein antigen promotes the generation of CTL J. Invest. Dermatol. 122 2004 1042 1049
18. S. Yotsumoto, Y. Aramaki, T. Kakiuchi, and S. Tsuchiya Induction of antigen-dependent interleukin-12 production by negatively charged liposomes encapsulating antigens Vaccine 22 2004 3503 3509
19. T. Sakamoto, E. Miyazaki, Y. Aramaki, H. Arima, M. Takahashi, Y. Kato, M. Koga, and S. Tsuchiya Improvement of dermatitis by iontophoretically delivered antisense oligonucleotides for interleukin-10 in NC/Nga mice Gene Ther. 11 2004 317 324
20. J.N. Kline, T.J. Waldschmidt, T.R. Businga, J.E. Lemish, J.V. Weinstock, P.S. Thorne, and A.M. Krieg Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma J. Immunol. 160 1998 2555 2559
21. J.N. Kline, K. Kitagaki, T.R. Businga, and V.V. Jain Treatment of established asthma in a murine model using CpG oligodeoxynucleotides Am. J. Physiol., Lung Cell Mol. Physiol. 283 2002 L170 L179
22. I. Hussain, and J.N. Kline CpG oligodeoxynucleotides: a novel therapeutic approach for atopic disorders Curr. Drug Targets Inflamm. Allergy 2 2003 199 205
23. S.C. Morris, K.B. Madden, J.J. Adamovicz, W.C. Gause, B.R. Hubbard, M.K. Gately, and F.D. Finkelman Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection J. Immunol. 152 1994 1047 1056
24. H.P. Tan, L.K. Lebeck, and S.L. Nehlsen-Cannarella Regulatory role of cytokines in IgE-mediated allergy J. Leukoc. Biol. 52 1992 115 118
25. C.L. King, C.C. Low, and T.B. Nutman IgE production in human helminth infection. Reciprocal interrelationship between IL-4 and IFN-gamma J. Immunol. 150 1993 1873 1880
26. K. Moser, K. Kriwet, A. Naik, Y.N. Kalia, and R.H. Guy Passive skin penetration enhancement and its quantification in vitro Eur. J. Pharm. Biopharm. 52 2001 103 112
27. A. Boonstra, C. Asselin-Paturel, M. Gilliet, C. Crain, G. Trinchieri, Y.J. Liu, and A. O'Garra Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation J. Exp. Med. 197 2003 101 109
28. L. Liu, X. Zhou, J. Shi, X. Xie, and Z. Yuan Toll-like receptor-9 induced by physical trauma mediates release of cytokines following exposure to CpG motif in mouse skin Immunology 110 2003 341 347
29. M. Yazdanbakhsh, A. van den Biggelaar, and R.M. Maizels Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease Trends Immunol. 22 2001 372 377
30. I. Muller, J.A. Garcia-Sanz, R. Titus, R. Behin, and J. Louis Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major Immunol. Rev. 112 1989 95 113
31. Y. Wu, Q. Zhou, P. Zheng, and Y. Liu CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen J. Exp. Med. 187 1998 1151 1156
32. E.Y. So, H.H. Park, and C.E. Lee IFN-gamma and IFN-alpha posttranscriptionally down-regulate the IL-4-induced IL-4 receptor gene expression J. Immunol. 165 2000 5472 5479
33. M. Kimura, S. Tsuruta, and T. Yoshida IL-4 production by PBMCs on stimulation with mite allergen is correlated with the level of serum IgE antibody against mite in children with bronchial asthma J. Allergy Clin. Immunol. 105 2000 327 332
34. H.B. Moon, E. Severinson, C. Heusser, S.G. Johansson, G. Moller, and U. Persson Regulation of IgG1 and IgE synthesis by interleukin 4 in mouse B cells Scand. J. Immunol. 30 1989 355 361
35. A. Bossie, and E.S. Vitetta IFN-gamma enhances secretion of IgG2a from IgG2a-committed LPS-stimulated murine B cells: implications for the role of IFN-gamma in class switching Cell. Immunol. 135 1991 95 104
36. H.J. Cho, K. Takabayashi, P.M. Cheng, M.D. Nguyen, M. Corr, S. Tuck, and E. Raz Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism Nat. Biotechnol. 18 2000 509 514
37. H. Shirota, K. Sano, N. Hirasawa, T. Terui, O.K. huchi, T. Hattori, K. Shirato, and G. Tamura Novel roles of CpG oligodeoxynucleotides as a leader for the sampling and presentation of CpG-tagged antigen by dendritic cells J. Immunol. 167 2001 66 74