Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis

Pharmaceutical Research

Volumn 22, Issue 12, 2005, Pages 2069-2078

  Abla, Nada ^a,b   Naik, Aarti ^a,b   Guy, Richard H ^a,c   Kalia, Yogeshvar N ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Centre Interuniversitaire de Recherche et d'Enseignement   (France)

^c University of Bath   (United Kingdom)

Author keywords

Charge molecular weight ratio; Iontophoresis; Peptide; Skin metabolism; Zwitterion

Indexed keywords

ACETYLTYROSYLPHENYLALANINE HYDROXIDE; AMINOPEPTIDASE; AMPHOLYTE; DIPEPTIDE DERIVATIVE; GLUTAMYL EPSILON LYSINE HYDROXIDE; HISTIDYLLYSINE HYDROXIDE; LYSINE DERIVATIVE; LYSINE HYDROXIDE; LYSYLLYSINE HYDROXIDE; PARACETAMOL; TYROSINE DERIVATIVE; TYROSYL DEXTRO ARGININAMIDE; TYROSYL DEXTRO ARGININE HYDROXIDE; TYROSYLGLUTAMINE HYDROXIDE; TYROSYLHISTIDINE HYDROXIDE; TYROSYLLYSINAMIDE; TYROSYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG METABOLISM; HYDROLYSIS; IN VITRO STUDY; IONTOPHORESIS; MOLECULAR WEIGHT; PH; PRIORITY JOURNAL; STEADY STATE; STRATUM CORNEUM;

ACETAMINOPHEN; ADMINISTRATION, CUTANEOUS; ALGORITHMS; AMINO ACIDS; ANIMALS; BUFFERS; DIPEPTIDES; EAR, EXTERNAL; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; IONTOPHORESIS; MOLECULAR WEIGHT; OSMOSIS; PEPTIDES; SKIN ABSORPTION; SPECTROPHOTOMETRY, ULTRAVIOLET; SWINE; TYROSINE;

EID: 29244432149     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-005-8110-2     Document Type: Article

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