메뉴 건너뛰기




Volumn 16, Issue 3, 2011, Pages 962-979

The neurobiology of APOE in schizophrenia and mood disorders

Author keywords

Apoliprotein E; Bipolar disorder; Depression; Low density lipoprotein receptor; Review; Schizophrenia

Indexed keywords

APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN RECEPTOR; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE;

EID: 79955040875     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3729     Document Type: Review
Times cited : (22)

References (202)
  • 1
    • 0029865093 scopus 로고    scopus 로고
    • Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins
    • DOI 10.1006/exnr.1996.0064
    • L. M. Fleming, K. H. Weisgraber, W. J. Strittmatter, J. C. Troncoso and G. V. W. Johnson: Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins. Exper Neurol 138, 252-260 (1996) (Pubitemid 26135201)
    • (1996) Experimental Neurology , vol.138 , Issue.2 , pp. 252-260
    • Fleming, L.M.1    Weisgraber, K.H.2    Strittmatter, W.J.3    Troncoso, J.C.4    Johnson, G.V.W.5
  • 2
    • 0033134708 scopus 로고    scopus 로고
    • Regulation of tau phosphorylation in microtubule fractions by apolipoprotein E
    • DOI 10.1002/(SICI)1097-4547(19990501)56:3<271::AID-JNR6>3.0.CO;2-5
    • D. Flaherty, Q. Lu, J. Soria and J. G. Wood: Regulation of tau phosphorylation in microtubule fractions by apolipoprotein E. J Neurosci Res 56, 271-274 (1999) (Pubitemid 29210617)
    • (1999) Journal of Neuroscience Research , vol.56 , Issue.3 , pp. 271-274
    • Flaherty, D.1    Lu, Q.2    Soria, J.3    Wood, J.G.4
  • 4
    • 0029958248 scopus 로고    scopus 로고
    • Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein
    • DOI 10.1074/jbc.271.47.30121
    • A. M. Fagan, G. Bu, Y. Sun, A. Daugherty and D. M. Holtzman: Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein. J Biol Chem 271, 30121-30125 (1996) (Pubitemid 26389653)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.47 , pp. 30121-30125
    • Fagan, A.M.1    Bu, G.2    Sun, Y.3    Daugherty, A.4    Holtzman, D.M.5
  • 5
    • 0141815698 scopus 로고    scopus 로고
    • Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A
    • DOI 10.1074/jbc.M303171200
    • Y. J. Zhu and D. Y. Hui: Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A. J Biol Chem, 278, 36257-36263 (2003) (Pubitemid 37139949)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.38 , pp. 36257-36263
    • Zhu, Y.1    Hui, D.Y.2
  • 10
    • 0029564615 scopus 로고
    • Apolipoprotein E type epsilon4 allele frequency is increased in patients with schizophrenia
    • DOI 10.1016/0304-3940(95)12218-4
    • C. R. Harrington, M. Roth, J. H. Xuereb, P. J. McKenna and C. M. Wischik: Apolipoprotein E type epsilon4 allele frequency is increased in patients with schizophrenia. Neurosci Lett, 202, 101-104 (1995) (Pubitemid 26011567)
    • (1995) Neuroscience Letters , vol.202 , Issue.1-2 , pp. 101-104
    • Harringtona, C.R.1    Roth, M.2    Xuereb, J.H.3    McKenna, P.J.4    Wischik, C.M.5
  • 12
    • 0020490536 scopus 로고
    • Human apolipoprotein-E - The complete amino-acid-sequence
    • S. C. Rall, K. H. Weisgraber and R. W. Mahley: Human apolipoprotein-E - The complete amino-acid-sequence. J Biol Chem, 257, 4171-4178 (1982)
    • (1982) J Biol Chem , vol.257 , pp. 4171-4178
    • Rall, S.C.1    Weisgraber, K.H.2    Mahley, R.W.3
  • 13
    • 0023899914 scopus 로고
    • Expression of the human apolipoprotein-E gene is regulated by multiple positive and negative elements
    • J. D. Smith, A. Melian, T. Leff and J. L. Breslow: Expression of the human apolipoprotein-E gene is regulated by multiple positive and negative elements. J Biol Chem, 263, 8300-8308 (1988)
    • (1988) J Biol Chem , vol.263 , pp. 8300-8308
    • Smith, J.D.1    Melian, A.2    Leff, T.3    Breslow, J.L.4
  • 14
    • 0024204381 scopus 로고
    • Enhanced apolipoprotein E production with normal hepatic mRNA levels in the Watanabe heritable hyperlipidemic rabbit
    • C. J. N. Rall, J. M. Hoeg, R. E. Gregg, S. W. Law, J. C. Monge, M. S. Meng, L. A. Zech and H. B. Brewer: Enhanced apolipoprotein-E production with normal hepatic messenger-RNA levels in the watanabe heritable hyperlipidemic rabbit. Arteriosclerosis, 8, 804-809 (1988) (Pubitemid 19005368)
    • (1988) Arteriosclerosis , vol.8 , Issue.6 , pp. 804-809
    • Rall, C.J.N.1    Hoeg, J.M.2    Gregg, R.E.3    Law, S.W.4    Monge, J.C.5    Meng, M.S.6    Zech, L.A.7    Brewer Jr., H.B.8
  • 16
    • 0033941425 scopus 로고    scopus 로고
    • Apolipoprotein E-low density lipoprotein receptor interaction: Influences of basic residue and amphipathic alpha-helix organization in the ligand
    • M. Zaiou, K. S. Arnold, Y. M. Newhouse, T. L. Innerarity, K. H. Weisgraber, M. L. Segall, M. C. Phillips and S. Lund-Katz: Apolipoprotein E-low density lipoprotein receptor interaction: influences of basic residue and amphipathic alphahelix organization in the ligand. J Lipid Res, 41, 1087-1095 (2000) (Pubitemid 30483013)
    • (2000) Journal of Lipid Research , vol.41 , Issue.7 , pp. 1087-1095
    • Zaiou, M.1    Arnold, K.S.2    Newhouse, Y.M.3    Innerarity, T.L.4    Weisgraber, K.H.5    Segall, M.L.6    Phillips, M.C.7    Lund-Katz, S.8
  • 17
    • 0020419894 scopus 로고
    • Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes
    • V. I. Zannis, J. L. Breslow, G. Utermann, R. W. Mahley, K. H. Weisgraber, R. J. Havel, J. L. Goldstein, M. S. Brown, G. Schonfeld, W. R. Hazzard and C. Blum: Proposed nomenclature of apoE-isoproteins, apoE-genotypes, and phenotypes. J Lipid Res, 23, 911-914 (1982) (Pubitemid 13244364)
    • (1982) Journal of Lipid Research , vol.23 , Issue.6 , pp. 911-914
    • Zannis, V.I.1    Breslow, J.L.2    Utermann, G.3
  • 18
    • 0029113023 scopus 로고
    • ApoE genotypes in Australia: Roles in early and late onset alzheimer's disease and Down's syndrome
    • R. N. Martins, R. Clarnette, C. Fisher, G. A. Broe, W. S. Brooks, P. Montgomery and S. E. Gandy: ApoE genotypes in Australia: roles in early and late onset alzheimer's disease and Down's syndrome. Neuroreport, 6, 1513-1516 (1995)
    • (1995) Neuroreport , vol.6 , pp. 1513-1516
    • Martins, R.N.1    Clarnette, R.2    Fisher, C.3    Broe, G.A.4    Brooks, W.S.5    Montgomery, P.6    Gandy, S.E.7
  • 19
    • 0020478765 scopus 로고
    • Abnormal lipoprotein receptor-binding activity of the human-E apoprotein due to cysteine-arginine interchange at a single site
    • K. H. Weisgraber, T. L. Innerarity and R. W. Mahley: Abnormal lipoprotein receptor-binding activity of the human-E apoprotein due to cysteine-arginine interchange at a single site. J Biol Chem 257, 2518-2521 (1982)
    • (1982) J Biol Chem , vol.257 , pp. 2518-2521
    • Weisgraber, K.H.1    Innerarity, T.L.2    Mahley, R.W.3
  • 20
    • 0034975285 scopus 로고    scopus 로고
    • Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth
    • R. B. DeMattos, L. L. Rudel and D. L. Williams: Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth. J Lipid Res, 42, 976-987 (2001) (Pubitemid 32545854)
    • (2001) Journal of Lipid Research , vol.42 , Issue.6 , pp. 976-987
    • DeMattos, R.B.1    Rudel, L.L.2    Williams, D.L.3
  • 21
    • 0028232662 scopus 로고
    • Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro
    • B. P. Nathan, S. Bellosta, D. A. Sanan, K. H. Weisgraber, R. W. Mahley and R. E. Pitas: Differentialeffects of apolipoproteins E3 and E4 on neuronal growth invitro. Science 264, 850-852 (1994) (Pubitemid 24193454)
    • (1994) Science , vol.264 , Issue.5160 , pp. 850-852
    • Nathan, B.P.1    Bellosta, S.2    Sanan, D.A.3    Weisgraber, K.H.4    Mahley, R.W.5    Pitas, R.E.6
  • 22
    • 0028850374 scopus 로고
    • Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma-cells produces differential-effects on neurite outgrowth
    • S. Bellosta, B. P. Nathan, M. Orth, L. M. Dong, R. W. Mahley and R. E. Pitas: Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma-cells produces differential-effects on neurite outgrowth. J Biol Chem, 270, 27063-27071 (1995)
    • (1995) J Biol Chem , vol.270 , pp. 27063-27071
    • Bellosta, S.1    Nathan, B.P.2    Orth, M.3    Dong, L.M.4    Mahley, R.W.5    Pitas, R.E.6
  • 23
    • 0020524629 scopus 로고
    • 146 → Gln), in a type III hyperlipoproteinemic subject with the E3/2 phenotype
    • S. C. Rall, K. H. Weisgraber, T. L. Innerarity, T. P. Bersot, C. B. Blum and R. W. Mahley: Identification of a new structural variant of human apolipoprotein-E, E2(Lys146→Gln), in a type-III hyperlipoproteinemic subject with the E3/2 phenotype. J Clin Invest, 72, 1288-1297 (1983) (Pubitemid 13013761)
    • (1983) Journal of Clinical Investigation , vol.72 , Issue.4 , pp. 1288-1297
    • Rall Jr., S.C.1    Weisgraber, K.H.2    Innerarity, T.L.3
  • 24
    • 0027987314 scopus 로고
    • Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels
    • DOI 10.1002/humu.1380040303
    • P. Deknijff, A. Vandenmaagdenberg, R. R. Frants and L. M. Havekes: Genetic-heterogeneity of apolipoprotein-E and its influence on plasma-lipid and lipoprotein levels. Hum Mutat, 4, 178-194 (1994) (Pubitemid 24319486)
    • (1994) Human Mutation , vol.4 , Issue.3 , pp. 178-194
    • De Knijff, P.1    Van Den Maagdenberg, A.M.J.M.2    Frants, R.R.3    Havekes, L.M.4
  • 26
    • 76749135871 scopus 로고    scopus 로고
    • Decoding of lipoprotein-receptor interactions: Properties of ligand binding modules governing interactions with apolipoprotein E
    • M. Guttman, J. H. Prieto, J. E. Croy and E. A. Komives: Decoding of Lipoprotein-Receptor Interactions: Properties of Ligand Binding Modules Governing Interactions with Apolipoprotein E. Biochemistry, 49, 1207-1216 (2010)
    • (2010) Biochemistry , vol.49 , pp. 1207-1216
    • Guttman, M.1    Prieto, J.H.2    Croy, J.E.3    Komives, E.A.4
  • 27
    • 0026778830 scopus 로고
    • Rabbit very low-density-lipoprotein receptor - A low-density-lipoprotein receptor-like protein with distinct ligand specificity
    • S. Takahashi, Y. Kawarabayasi, T. Nakai, J. Sakai and T. Yamamoto: Rabbit very low-density-lipoprotein receptor - a low-density-lipoprotein receptor-like protein with distinct ligand specificity. Proc Natl Acad Sci USA, 89, 9252-9256 (1992)
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9252-9256
    • Takahashi, S.1    Kawarabayasi, Y.2    Nakai, T.3    Sakai, J.4    Yamamoto, T.5
  • 28
    • 0024449363 scopus 로고
    • The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein
    • DOI 10.1038/341162a0
    • U. Beisiegel, W. Weber, G. Ihrke, J. Herz and K. K. Stanley: The LDL receptor related protein, LRP, is an apolipoprotein E-binding protein. Nature, 341, 162-164 (1989) (Pubitemid 19222781)
    • (1989) Nature , vol.341 , Issue.6238 , pp. 162-164
    • Beisiegel, U.1    Weber, W.2    Ihrke, G.3    Herz, J.4    Stanley, K.K.5
  • 30
    • 35248837870 scopus 로고    scopus 로고
    • A role for LRP4 in neuronal cell viability is related to apoE-binding
    • DOI 10.1016/j.brainres.2007.08.035, PII S0006899307018628
    • Y. Lu, Q. B. Tian, S. Endo and T. Suzuki: A role for LRP4 in neuronal cell viability is related to apoE-binding. Brain Res, 1177, 19-28 (2007) (Pubitemid 47561888)
    • (2007) Brain Research , vol.1177 , Issue.1 , pp. 19-28
    • Lu, Y.1    Tian, Q.B.2    Endo, S.3    Suzuki, T.4
  • 31
    • 0029922119 scopus 로고    scopus 로고
    • Human apolipoprotein e receptor 2 - A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
    • D. H. Kim, H. Iijima, K. Goto, J. Sakai, H. Ishii, H. J. Kim, H. Suzuki, H. Kondo, S. Saeki and T. Yamamoto: Human apolipoprotein E receptor 2 - A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain. J Biol Chem, 271, 8373-8380 (1996)
    • (1996) J Biol Chem , vol.271 , pp. 8373-8380
    • Kim, D.H.1    Iijima, H.2    Goto, K.3    Sakai, J.4    Ishii, H.5    Kim, H.J.6    Suzuki, H.7    Kondo, H.8    Saeki, S.9    Yamamoto, T.10
  • 34
    • 0028326257 scopus 로고
    • Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL receptor-related protein
    • F. T. Yen, C. J. Mann, L. M. Guermani, N. F. Hannouche, N. Hubert, C. A. Hornick, V. N. Bordeau, G. Agnani and B. E. Bihain: Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL receptor-related protein. Biochemistry, 33, 1172-1180 (1994) (Pubitemid 24072447)
    • (1994) Biochemistry , vol.33 , Issue.5 , pp. 1172-1180
    • Yen, F.T.1    Mann, C.J.2    Guermani, L.M.3    Hannouche, N.F.4    Hubert, N.5    Hornick, C.A.6    Bordeau, V.N.7    Agnani, G.8    Bihain, B.E.9
  • 35
    • 0032127807 scopus 로고    scopus 로고
    • CDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13.2
    • DOI 10.1006/geno.1998.5339
    • H. Ishii, D. H. Kim, T. Fujita, Y. Endo, S. Saeki and T. T. Yamamoto: cDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13.2. Genomics 51, 132-135 (1998) (Pubitemid 28373382)
    • (1998) Genomics , vol.51 , Issue.1 , pp. 132-135
    • Ishii, H.1    Kim, D.-H.2    Fujita, T.3    Endo, Y.4    Saeki, S.5    Yamamoto, T.T.6
  • 36
    • 66349124185 scopus 로고    scopus 로고
    • Expanding functions of lipoprotein receptors
    • J. Herz, Y. Chen, I. Masiulis and L. Zhou: Expanding functions of lipoprotein receptors. J Lipid Res, 50 Suppl, S287-92 (2009)
    • (2009) J Lipid Res , Issue.50 SUPPL.
    • Herz, J.1    Chen, Y.2    Masiulis, I.3    Zhou, L.4
  • 37
    • 0034796509 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor family: Endocytosis and signal transduction
    • DOI 10.1385/MN:23:1:53
    • Y. Li, J. Cam and G. Bu: Low-density lipoprotein receptor family: endocytosis and signal transduction. Mol Neurobiol, 23(1), 53-67 (2001) (Pubitemid 32948272)
    • (2001) Molecular Neurobiology , vol.23 , Issue.1 , pp. 53-67
    • Li, Y.1    Cam, J.2    Bu, G.3
  • 38
    • 34247557490 scopus 로고    scopus 로고
    • The LDL receptor-related protein (LRP) family: An old family of proteins with new physiological functions
    • DOI 10.1080/07853890701214881, PII 777639280
    • P. May, E. Woldt, R. L. Matz and P. Boucher: The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions. Ann Med, 39, 219-28 (2007) (Pubitemid 46676481)
    • (2007) Annals of Medicine , vol.39 , Issue.3 , pp. 219-228
    • May, P.1    Woldt, E.2    Matz, R.L.3    Boucher, P.4
  • 39
    • 27144457812 scopus 로고    scopus 로고
    • Molecular mechanisms of lipoprotein receptor signalling
    • DOI 10.1007/s00018-005-5231-z
    • P. May, J. Herz and H. H. Bock: Molecular mechanisms of lipoprotein receptor signalling. Cell Mol Life Sci, 62(19-20), 2325-2338 (2005) (Pubitemid 41500548)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.19-20 , pp. 2325-2338
    • May, P.1    Herz, J.2    Bock, H.H.3
  • 40
    • 0033213256 scopus 로고    scopus 로고
    • Reelin is a ligand for lipoprotein receptors
    • DOI 10.1016/S0896-6273(00)80860-0
    • G. D'Arcangelo, R. Homayouni, L. Keshvara, D. S. Rice, M. Sheldon and T. Curran: Reelin is a ligand for lipoprotein receptors. Neuron 24, 471-479 (1999) (Pubitemid 29508420)
    • (1999) Neuron , vol.24 , Issue.2 , pp. 471-479
    • D'Arcangelo, G.1    Homayouni, R.2    Keshvara, L.3    Rice, D.S.4    Sheldon, M.5    Curran, T.6
  • 43
    • 47149104839 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein
    • Z. Y. Sheng, M. Prorok, B. E. Brown and F. J. Castellino: N-methyl-D-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein. Neuropharmacology, 55, 204-214 (2008)
    • (2008) Neuropharmacology , vol.55 , pp. 204-214
    • Sheng, Z.Y.1    Prorok, M.2    Brown, B.E.3    Castellino, F.J.4
  • 44
    • 0037961657 scopus 로고    scopus 로고
    • Apolipoprotein E (APOE) polymorphism influences serum APOE levels in Alzheimer's disease patients and centenarians
    • DOI 10.1097/00001756-200303240-00016
    • F. Panza, V. Solfrizzi, A. M. Colacicco, A. M. Basile, A. D'Introno, C. Capurso, M. Sabba, S. Capurso and A. Capurso: Apolipoprotein E (APOE) polymorphism influences serum APOE levels in Alzheimer's disease patients and centenarians. Neuroreport, 14, 605-608 (2003) (Pubitemid 36528999)
    • (2003) NeuroReport , vol.14 , Issue.4 , pp. 605-608
    • Panza, F.1    Solfrizzi, V.2    Colacicco, A.M.3    Basile, A.M.4    D'Introno, A.5    Capurso, C.6    Sabba, M.7    Capurso, S.8    Capurso, A.9
  • 45
    • 0020047721 scopus 로고
    • Atherogenic hyperlipoproteinemia. The cellular and molecular biology of plasma lipoproteins altered by dietary fat and cholesterol
    • R. W. Mahley: Atherogenic hyperlipoproteinemia. The cellular and molecular biology of plasma lipoproteins altered by dietary fat and cholesterol. Med Clin North Am 66(2), 375-402 (1982) (Pubitemid 12115372)
    • (1982) Medical Clinics of North America , vol.66 , Issue.2 , pp. 375-402
    • Mahley, R.W.1
  • 47
    • 0023280054 scopus 로고
    • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain
    • R. E. Pitas, J. K. Boyles, S. H. Lee, D. Hui and K. H. Weisgraber: Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain. J Biol Chem, 262, 14352-60 (1987) (Pubitemid 17152101)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.29 , pp. 14352-14360
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Hui, D.4    Weisgraber, K.H.5
  • 48
    • 15944389528 scopus 로고    scopus 로고
    • Cholesterol homeostasis in neurons and glial cells
    • DOI 10.1016/j.semcdb.2005.01.005, Cellular Cholesterol Metabolism and Trafficking and Apoptosis in Development
    • J. E. Vance, H. Hayashi and B. Karten: Cholesterol homeostasis in neurons and glial cells. Semin Cell Dev Biol, 16, 193-212 (2005) (Pubitemid 40432121)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.2 , pp. 193-212
    • Vance, J.E.1    Hayashi, H.2    Karten, B.3
  • 49
    • 0027298061 scopus 로고
    • Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats
    • DOI 10.1016/0306-4522(93)90456-P
    • J. Poirier, A. Baccichet, D. Dea and S. Gauthier: Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats. Neuroscience, 55, 81-90 (1993) (Pubitemid 23194987)
    • (1993) Neuroscience , vol.55 , Issue.1 , pp. 81-90
    • Poirier, J.1    Baccichet, A.2    Dea, D.3    Gauthier, S.4
  • 51
    • 33645808672 scopus 로고    scopus 로고
    • Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
    • R. W. Mahley, K. H. Weisgraber and Y. Huang: Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc Natl Acad Sci USA, 103, 5644-5651 (2006)
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5644-5651
    • Mahley, R.W.1    Weisgraber, K.H.2    Huang, Y.3
  • 52
    • 0004982358 scopus 로고    scopus 로고
    • Apolipoprotein-E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral-tissues of rats and marmosets
    • N. A. Elshourbagy, W. S. Liao, R. W. Mahley and J. M. Taylor: Apolipoprotein-E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral-tissues of rats and marmosets. Proc Natl Acad Sci USA, 82, 203-207
    • Proc Natl Acad Sci USA , vol.82 , pp. 203-207
    • Elshourbagy, N.A.1    Liao, W.S.2    Mahley, R.W.3    Taylor, J.M.4
  • 53
    • 0022350033 scopus 로고
    • Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
    • J. K. Boyles, R. E. Pitas, E. Wilson, R. W. Mahley and J. M. Taylor: Apolipoprotein-E associated with astrocytic glia of the central nervous-system and with nonmyelinating glia of the peripheral nervous-system. J Clinl Invest, 76, 1501-1513 (1985) (Pubitemid 16193568)
    • (1985) Journal of Clinical Investigation , vol.76 , Issue.4 , pp. 1501-1513
    • Boyles, J.K.1    Pitas, R.E.2    Wilson, E.3
  • 54
    • 0025826774 scopus 로고
    • Astrocytic apolipoprotein-E messenger-RNA and GFAP messenger-RNA in hippocampus after entorhinal cortex lesioning
    • J. Poirier, M. Hess, P. C. May and C. E. Finch: Astrocytic apolipoprotein-E messenger-RNA and GFAP messenger-RNA in hippocampus after entorhinal cortex lesioning. Mol Brain Res, 11, 97-106 (1991)
    • (1991) Mol Brain Res , vol.11 , pp. 97-106
    • Poirier, J.1    Hess, M.2    May, P.C.3    Finch, C.E.4
  • 56
    • 0029912740 scopus 로고    scopus 로고
    • Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain
    • F. Bao, H. Arai, S. Matsushita, S. Higuchi and H. Sasaki: Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain. Neuroreport, 7, 1733-1739 (1996) (Pubitemid 26348246)
    • (1996) NeuroReport , vol.7 , Issue.11 , pp. 1733-1739
    • Bao, F.1    Arai, H.2    Matsushita, S.3    Higuchi, S.4    Sasaki, H.5
  • 59
    • 0033135292 scopus 로고    scopus 로고
    • Tripartite synapses: Glia, the unacknowledged partner
    • DOI 10.1016/S0166-2236(98)01349-6, PII S0166223698013496
    • A. Araque, V. Parpura, R. P. Sanzgiri and P. G. Haydon: Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci, 22, 208-215 (1999) (Pubitemid 29202082)
    • (1999) Trends in Neurosciences , vol.22 , Issue.5 , pp. 208-215
    • Araque, A.1    Parpura, V.2    Sanzgiri, R.P.3    Haydon, P.G.4
  • 62
    • 0035834416 scopus 로고    scopus 로고
    • CNS synaptogenesis promoted by glia-derived cholesterol
    • DOI 10.1126/science.294.5545.1354
    • D. H. Mauch, K. Nagler, S. Schumacher, C. Goritz, E. C. Muller, A. Otto and F. W. Pfrieger: CNS synaptogenesis promoted by glia-derived cholesterol. Science, 294, 1354-1357 (2001) (Pubitemid 33063104)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1354-1357
    • Mauch, D.H.1    Nagier, K.2    Schumacher, S.3    Goritz, C.4    Muller, E.-C.5    Otto, A.6    Pfrieger, F.W.7
  • 63
    • 0015520940 scopus 로고
    • A cholinergicadrenergic hypothesis of mania and depression
    • D. S. Janowsky, M. K. el-Yousef, J. M. Davis and H. J. Sekerke: A cholinergicadrenergic hypothesis of mania and depression. Lancet, 2, 632-635 (1972)
    • (1972) Lancet , vol.2 , pp. 632-635
    • Janowsky, D.S.1    El-Yousef, M.K.2    Davis, J.M.3    Sekerke, H.J.4
  • 64
    • 67349144696 scopus 로고    scopus 로고
    • Decreased muscarinic receptor binding in the frontal cortex of bipolar disorder and major depressive disorder subjects
    • A. S. Gibbons, E. Scarr, C. McLean, S. Sundram and B. Dean: Decreased muscarinic receptor binding in the frontal cortex of bipolar disorder and major depressive disorder subjects. J Affect Disord, 116, 184-191 (2009)
    • (2009) J Affect Disord , vol.116 , pp. 184-191
    • Gibbons, A.S.1    Scarr, E.2    McLean, C.3    Sundram, S.4    Dean, B.5
  • 65
    • 70350446516 scopus 로고    scopus 로고
    • Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia
    • E. Scarr, T. F. Cowie, S. Kanellakis, S. Sundram, C. Pantelis and B. Dean: Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia. Mol Psychiatry, 14, 1017-1023, (2009) :
    • (2009) Mol Psychiatry , vol.14 , pp. 1017-1023
    • Scarr, E.1    Cowie, T.F.2    Kanellakis, S.3    Sundram, S.4    Pantelis, C.5    Dean, B.6
  • 66
    • 23844461847 scopus 로고    scopus 로고
    • Cortical glutamatergic markers in schizophrenia
    • DOI 10.1038/sj.npp.1300758
    • E. Scarr, M. Beneyto, J. H. Meador-Woodruff and B. Dean: Cortical glutamatergic markers in schizophrenia. Neuropsychopharmacology, 30, 1521-1531 (2005) (Pubitemid 41153124)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.8 , pp. 1521-1531
    • Scarr, E.1    Beneyto, M.2    Meador-Woodruff, J.H.3    Dean, B.4
  • 67
    • 0042009696 scopus 로고    scopus 로고
    • Decreased hippocampal NMDA, but not kainate or AMPA receptors in bipolar disorder
    • DOI 10.1034/j.1399-5618.2003.00024.x
    • E. Scarr, G. Pavey, S. Sundram, A. MacKinnon and B. Dean: Decreased hippocampal NMDA, but not kainate or AMPA receptors in bipolar disorder. Bipolar Disord. 5, 257-264 (2003) (Pubitemid 37009889)
    • (2003) Bipolar Disorders , vol.5 , Issue.4 , pp. 257-264
    • Scarr, E.1    Pavey, G.2    Sundram, S.3    MacKinnon, A.4    Dean, B.5
  • 68
    • 0035834416 scopus 로고    scopus 로고
    • CNS synaptogenesis promoted by glia-derived cholesterol
    • DOI 10.1126/science.294.5545.1354
    • D. H. Mauch, K. Nagler, S. Schumacher, C. Goritz, E. C. Muller, A. Otto and F. W. Pfrieger: CNS synaptogenesis promoted by glia-derived cholesterol. Science, 294, 1354-1357 (2001) (Pubitemid 33063104)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1354-1357
    • Mauch, D.H.1    Nagier, K.2    Schumacher, S.3    Goritz, C.4    Muller, E.-C.5    Otto, A.6    Pfrieger, F.W.7
  • 69
    • 16244405249 scopus 로고    scopus 로고
    • Multiple pathways of apolipoprotein E signaling in primary neurons
    • DOI 10.1111/j.1471-4159.2004.03007.x
    • H. S. Hoe, D. C. Harris and G. W. Rebeck: Multiple pathways of apolipoprotein E signaling in primary neurons. J Neurochem, 93, 145-155 (2005) (Pubitemid 40463524)
    • (2005) Journal of Neurochemistry , vol.93 , Issue.1 , pp. 145-155
    • Hoe, H.-S.1    Harris, D.C.2    Rebeck, G.W.3
  • 70
    • 33748430000 scopus 로고    scopus 로고
    • Effects of apoE on neuronal signaling and APP processing in rodent brain
    • DOI 10.1016/j.brainres.2006.07.035, PII S0006899306020579
    • H. S. Hoe, A. Pocivavsek, H. Dai, G. Chakraborty, D. C. Harris and G. W. Rebeck: Effects of apoE on neuronal signaling and APP processing in rodent brain. Brain Res, 1112, 70-79 (2006) (Pubitemid 44344621)
    • (2006) Brain Research , vol.1112 , Issue.1 , pp. 70-79
    • Hoe, H.-S.1    Pocivavsek, A.2    Dai, H.3    Chakraborty, G.4    Harris, D.C.5    Rebeck, G.W.6
  • 71
    • 0030741533 scopus 로고    scopus 로고
    • Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis
    • DOI 10.1074/jbc.272.29.17972
    • P. M. Sullivan, H. Mezdour, Y. Aratani, C. Knouff, J. Najib, R. L. Reddick, S. H. Quarfordt and N. Maeda: Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J Biol Chem, 272, 17972-17980 (1997) (Pubitemid 27306374)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.29 , pp. 17972-17980
    • Sullivan, P.M.1    Mezdour, H.2    Aratani, Y.3    Knouff, C.4    Najib, J.5    Reddick, R.L.6    Quarfordt, S.H.7    Maeda, N.8
  • 73
    • 36549071668 scopus 로고    scopus 로고
    • Apolipoprotein E Affects Both Myelin Breakdown and Cognition: Implications for Age-Related Trajectories of Decline Into Dementia
    • DOI 10.1016/j.biopsych.2007.03.024, PII S0006322307003186
    • G. Bartzokis, P. H. Lu, D. H. Geschwind, K. Tingus, D. Huang, M. F. Mendez, N. Edwards and J. Mintz: Apolipoprotein E affects both myelin breakdown and cognition: implications for age-related trajectories of decline into dementia. Biol Psychiatry, 62, 1380-1387 (2007) (Pubitemid 350180726)
    • (2007) Biological Psychiatry , vol.62 , Issue.12 , pp. 1380-1387
    • Bartzokis, G.1    Lu, P.H.2    Geschwind, D.H.3    Tingus, K.4    Huang, D.5    Mendez, M.F.6    Edwards, N.7    Mintz, J.8
  • 74
    • 4544297239 scopus 로고    scopus 로고
    • Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons
    • DOI 10.1074/jbc.M401055200
    • Z. Qiu, B. T. Hyman and G. W. Rebeck: Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons. J Biol Chem, 279, 34948-34956 (2004) (Pubitemid 39318131)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.33 , pp. 34948-34956
    • Qiu, Z.1    Hyman, B.T.2    Rebeck, G.W.3
  • 75
    • 4644298544 scopus 로고    scopus 로고
    • Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein e
    • DOI 10.1016/j.neulet.2004.07.084, PII S0304394004009401
    • H. W. Kitamura, H. Hamanaka, M. Watanabe, K. Wada, C. Yamazaki, S. C. Fujita, T. Manabe and N. Nukina: Agedependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E. Neurosci Lett, 369, 173-178 (2004) (Pubitemid 39298903)
    • (2004) Neuroscience Letters , vol.369 , Issue.3 , pp. 173-178
    • Kitamura, H.W.1    Hamanaka, H.2    Watanabe, M.3    Wada, K.4    Yamazaki, C.5    Fujita, S.C.6    Manabe, T.7    Nukina, N.8
  • 76
    • 0034633648 scopus 로고    scopus 로고
    • Genetics and visual attention: Selective deficits in healthy adult carriers of the epsilon 4 allele of the apolipoprotein e gene
    • P. M. Greenwood, T. Sunderland, J. L. Friz and R. Parasuraman: Genetics and visual attention: selective deficits in healthy adult carriers of the epsilon 4 allele of the apolipoprotein E gene. Proc Natl Acad Sci USA, 97, 11661-11666 (2000)
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11661-11666
    • Greenwood, P.M.1    Sunderland, T.2    Friz, J.L.3    Parasuraman, R.4
  • 77
    • 0029440749 scopus 로고
    • Episodic memory changes are associated with the APOE-epsilon4 allele in nondemented older adults
    • M. W. Bondi, D. P. Salmon, A. U. Monsch, D. Galasko, N. Butters, M. R. Klauber, L. J. Thal and T. Saitoh: Episodic memory changes are associated with the APOE-epsilon 4 allele in nondemented older adults. Neurology, 45(12), 2203-2206 (1995) (Pubitemid 27100249)
    • (1995) Neurology , vol.45 , Issue.12 , pp. 2203-2206
    • Bondi, M.W.1    Salmon, D.P.2    Monsch, A.U.3    Galasko, D.4    Butters, N.5    Klauber, M.R.6    Thal, L.J.7    Saitoh, T.8
  • 78
    • 15744378392 scopus 로고    scopus 로고
    • Human apoE targeted replacement mouse lines: H-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior
    • DOI 10.1016/j.bbr.2004.09.019
    • J. Grootendorst, A. Bour, E. Vogel, C. Kelche, P. M. Sullivan, J. C. Dodart, K. Bales and C. Mathis: Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior. Behav Brain Res, 159, 1-14 (2005) (Pubitemid 40410579)
    • (2005) Behavioural Brain Research , vol.159 , Issue.1 , pp. 1-14
    • Grootendorst, J.1    Bour, A.2    Vogel, E.3    Kelche, C.4    Sullivan, P.M.5    Dodart, J.-C.6    Bales, K.7    Mathis, C.8
  • 81
    • 33845299006 scopus 로고    scopus 로고
    • Impairments in spatial memory retention of GFAP-apoE4 female mice
    • DOI 10.1016/j.bbr.2006.10.024, PII S0166432806005833
    • P. van Meer, S. Acevedo and J. Raber: Impairments in spatial memory retention of GFAP-apoE4 female mice. Behav Brain Res, 176, 372-375 (2007) (Pubitemid 44880100)
    • (2007) Behavioural Brain Research , vol.176 , Issue.2 , pp. 372-375
    • Van Meer, P.1    Acevedo, S.2    Raber, J.3
  • 82
    • 0028844138 scopus 로고
    • Neurodegeneration in the central nervous system of apoE-deficient mice
    • E. Masliah, M. Mallory, N. Ge, M. Alford, I. Veinbergs and A. D. Roses: Neurodegeneration in the central nervous system of apoE-deficient mice. Exp Neurol 136(2), 107-122 (1995)
    • (1995) Exp Neurol , vol.136 , Issue.2 , pp. 107-122
    • Masliah, E.1    Mallory, M.2    Ge, N.3    Alford, M.4    Veinbergs, I.5    Roses, A.D.6
  • 83
    • 0000854535 scopus 로고    scopus 로고
    • Schizophrenia, schizophreniform disorder, and delusional disorders
    • Ed R. E. Hales, S. C. Yudofsky&J. A. Talbott. American Psychiatric Press, Washington, DC
    • D. W. Black and N. Andreasen: Schizophrenia, schizophreniform disorder, and delusional disorders. In: The American Psychiatric Press Textbook of Psychiatry. Ed R. E. Hales, S. C. Yudofsky&J. A. Talbott. American Psychiatric Press, Washington, DC (1999)
    • (1999) The American Psychiatric Press Textbook of Psychiatry
    • Black, D.W.1    Andreasen, N.2
  • 84
    • 0027394523 scopus 로고
    • Altered distribution of nicotinamide-adenine dinucleotide phosphate- diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development
    • S. Akbarian, W. E. Bunney, Jr., S. G. Potkin, S. B. Wigal, J. O. Hagman, C. A. Sandman and E. G. Jones: Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development. Arch Gen Psychiatry, 50, 169-77 (1993) (Pubitemid 23077471)
    • (1993) Archives of General Psychiatry , vol.50 , Issue.3 , pp. 169-177
    • Akbarian, S.1    Bunney Jr., W.E.2    Potkin, S.G.3    Wigal, S.B.4    Hagman, J.O.5    Sandman, C.A.6    Jones, E.G.7
  • 85
    • 0028034202 scopus 로고
    • Thalamic abnormalities in schizophrenia visualized through magnetic resonance image averaging
    • N. C. Andreasen, S. Arndt, V. Swayze, 2nd, T. Cizadlo, M. Flaum, D. O'Leary, J. C. Ehrhardt and W. T. Yuh: Thalamic abnormalities in schizophrenia visualized through magnetic resonance image averaging. Science, 266, 294-8 (1994) (Pubitemid 24343518)
    • (1994) Science , vol.266 , Issue.5183 , pp. 294-298
    • Andreasen, N.C.1    Arndt, S.2    Swayze II, V.3    Cizadlo, T.4    Flaum, M.5    O'Leary, D.6    Ehrhardt, J.C.7    Yuh, W.T.C.8
  • 86
    • 0031945083 scopus 로고    scopus 로고
    • Noise stress impairs prefrontal cortical cognitive function in monkeys: Evidence for a hyperdopaminergic mechanism
    • DOI 10.1001/archpsyc.55.4.362
    • A. F. Arnsten and P. S. Goldman-Rakic: Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism. Arch Gen Psychiatry, 55, 362-368 (1998) (Pubitemid 28173626)
    • (1998) Archives of General Psychiatry , vol.55 , Issue.4 , pp. 362-368
    • Arnsten, A.F.T.1    Goldman-Rakic, P.S.2
  • 87
    • 0031781132 scopus 로고    scopus 로고
    • Model generation and testing to probe neural circuitry in the cingulate cortex of postmortem schizophrenic brain
    • F. M. Benes: Model generation and testing to probe neural circuitry in the cingulate cortex of postmortem schizophrenic brain. Schizophr Bull, 24, 219-230 (1998) (Pubitemid 28404982)
    • (1998) Schizophrenia Bulletin , vol.24 , Issue.2 , pp. 219-230
    • Benes, F.M.1
  • 88
    • 0022616146 scopus 로고
    • Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics
    • F. M. Benes, J. Davidson and E. D. Bird: Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch Gen Psychiatry, 43, 31-35 (1986) (Pubitemid 16148968)
    • (1986) Archives of General Psychiatry , vol.43 , Issue.1 , pp. 31-35
    • Benes, F.M.1    Davidson, J.2    Bird, E.D.3
  • 89
    • 0000049816 scopus 로고    scopus 로고
    • Elevated neuronal density in prefrontal area 46 in brains from schizophrenic patients: Application of a three-dimensional, stereologic counting method
    • DOI 10.1002/(SICI)1096-9861(19980316)392:3<402::AID-CNE9>3.0.CO;2-5
    • L. D. Selemon, G. Rajkowska and P. S. Goldman-Rakic: Elevated neuronal density in prefrontal area 46 in brains from schizophrenic patients: application of a threedimensional, stereologic counting method. J Comp Neurol, 392, 402-412 (1998) (Pubitemid 28165894)
    • (1998) Journal of Comparative Neurology , vol.392 , Issue.3 , pp. 402-412
    • Selemon, L.D.1    Rajkowska, G.2    Goldman-Rakic, P.S.3
  • 91
    • 0033956237 scopus 로고    scopus 로고
    • Schizophrenia: Genes and environment
    • DOI 10.1016/S0006-3223(99)00289-9, PII S0006322399002899
    • M. Tsuang: Schizophrenia: genes and environment. Biol Psychiatry, 47, 210-220 (2000) (Pubitemid 30077397)
    • (2000) Biological Psychiatry , vol.47 , Issue.3 , pp. 210-220
    • Tsuang, M.1
  • 93
    • 24944483155 scopus 로고    scopus 로고
    • Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers
    • DOI 10.1016/j.molbrainres.2005.06.006, PII S0169328X05002603
    • S. Mexal, M. Frank, R. Berger, C. E. Adams, R. G. Ross, R. Freedman and S. Leonard: Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. Brain Res. Mol Brain Res, 139, 317-32 (2005) (Pubitemid 41317945)
    • (2005) Molecular Brain Research , vol.139 , Issue.2 , pp. 317-332
    • Mexal, S.1    Frank, M.2    Berger, R.3    Adams, C.E.4    Ross, R.G.5    Freedman, R.6    Leonard, S.7
  • 94
    • 0036843296 scopus 로고    scopus 로고
    • Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: A preliminary study
    • DOI 10.1016/S0920-9964(01)00377-2, PII S0920996401003772
    • M. P. Vawter, J. M. Crook, T. M. Hyde, J. E. Kleinman, D. R. Weinberger, K. G. Becker and W. J. Freed: Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study. Schizophr Res, 58, 11-20 (2002) (Pubitemid 35287279)
    • (2002) Schizophrenia Research , vol.58 , Issue.1 , pp. 11-20
    • Vawter, M.P.1    Crook, J.M.2    Hyde, T.M.3    Kleinman, J.E.4    Weinberger, D.R.5    Becker, K.G.6    Freed, W.J.7
  • 95
    • 0033637841 scopus 로고    scopus 로고
    • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
    • K. Mirnics, F. A. Middleton, A. Marquez, D. A. Lewis and P. Levitt: Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron, 28, 53-67 (2000)
    • (2000) Neuron , vol.28 , pp. 53-67
    • Mirnics, K.1    Middleton, F.A.2    Marquez, A.3    Lewis, D.A.4    Levitt, P.5
  • 96
    • 0035061298 scopus 로고    scopus 로고
    • Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia
    • DOI 10.1038/sj.mp.4000866
    • K. Mirnics, F. A. Middleton, G. D. Stanwood, D. A. Lewis and P. Levitt: Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mol Psychiatry, 6, 293-301 (2001) (Pubitemid 32275674)
    • (2001) Molecular Psychiatry , vol.6 , Issue.3 , pp. 293-301
    • Mirnics, K.1    Middleton, F.A.2    Stanwood, G.D.3    Lewis, D.A.4    Levitt, P.5
  • 97
    • 0037705995 scopus 로고    scopus 로고
    • Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia
    • T. Hashimoto, D. W. Volk, S. M. Eggan, K. Mirnics, J. N. Pierri, Z. Sun, A. R. Sampson and D. A. Lewis: Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. J Neurosci, 23, 6315-6326 (2003) (Pubitemid 36875633)
    • (2003) Journal of Neuroscience , vol.23 , Issue.15 , pp. 6315-6326
    • Hashimoto, T.1    Volk, D.W.2    Eggan, S.M.3    Mirnics, K.4    Pierri, J.N.5    Sun, Z.6    Sampson, A.R.7    Lewis, D.A.8
  • 100
    • 0033889344 scopus 로고    scopus 로고
    • Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
    • I. Tesseur, J. Van Dorpe, K. Spittaels, C. Van den Haute, D. Moechars and F. Van Leuven: Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice. Am J Pathol, 156, 951-964 (2000) (Pubitemid 30626953)
    • (2000) American Journal of Pathology , vol.156 , Issue.3 , pp. 951-964
    • Tesseur, I.1    Van Dorpe, J.2    Spittaels, K.3    Van Den Haute, C.4    Moechars, D.5    Van Leuven, F.6
  • 101
    • 0032080001 scopus 로고    scopus 로고
    • Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: Implications for Alzheimer's disease
    • D. J. Stone, I. Rozovsky, T. E. Morgan, C. P. Anderson and C. E. Finch: Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: Implications for Alzheimer's disease. J Neurosci, 18, 3180-3185 (1998) (Pubitemid 28186010)
    • (1998) Journal of Neuroscience , vol.18 , Issue.9 , pp. 3180-3185
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Finch, C.E.5
  • 102
    • 0038121679 scopus 로고    scopus 로고
    • Association of APOE gene with schizophrenia in Chinese: A possible risk factor in times of malnutrition
    • DOI 10.1016/S0920-9964(02)00384-5
    • W. Liu, G. Breen, J. Zhang, S. Li, N. Gu, G. Feng, S. Bai, T. Shen, A. Yu, H. Xue, D. St Clair and L. He: Association of APOE gene with schizophrenia in Chinese: a possible risk factor in times of malnutrition. Schizophr Res 62, 225-230 (2003) (Pubitemid 36773931)
    • (2003) Schizophrenia Research , vol.62 , Issue.3 , pp. 225-230
    • Liu, W.1    Breen, G.2    Zhang, J.3    Li, S.4    Gu, N.5    Feng, G.6    Bai, S.7    Shen, T.8    Yu, A.9    Xue, H.10    St Clair, D.11    He, L.12
  • 103
    • 0030009177 scopus 로고    scopus 로고
    • Lack of association between schizophrenia and the apolipoprotein E epsilon4 allele
    • DOI 10.1007/BF02188951
    • E. Jonsson, L. Lannfelt, B. Engvall and G. Sedvall: Lack of association between schizophrenia and the apolipoprotein E epsilon 4 allele. European Archives of Psychiatry and Clinical Neuroscience 246(4), 182-4 (1996) doi:10.1007/BF02188951 (Pubitemid 26225920)
    • (1996) European Archives of Psychiatry and Clinical Neuroscience , vol.246 , Issue.4 , pp. 182-184
    • Jonsson, E.1    Lannfelt, L.2    Engvall, B.3    Sedvall, G.4
  • 104
    • 0030996885 scopus 로고    scopus 로고
    • Apolipoprotein E genotype in schizophrenia: Frequency, age of onset, and neuropathologic features
    • S. E. Arnold, E. Joo, M. G. Martinoli, N. Roy, J. Q. Trojanowski, R. E. Gur, T. Cannon and R. A. Price: Apolipoprotein E genotype in schizophrenia: frequency, age of onset, and neuropathologic features. Neuroreport, 8, 1523-1526 (1997) (Pubitemid 27242568)
    • (1997) NeuroReport , vol.8 , Issue.6 , pp. 1523-1526
    • Arnold, S.E.1    Joo, E.2    Martinoli, M.-G.3    Roy, N.4    Trojanowski, J.Q.5    Gur, R.E.6    Cannon, T.7    Price, R.A.8
  • 108
    • 0031588092 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 and clinical phenotype in schizophrenia [3]
    • D. Pickar, A. K. Malhotra, W. Rooney, A. Breier and D. Goldman: Apolipoprotein E epsilon 4 and clinical phenotype in schizophrenia. Lancet, 350, 930-931 (1997) (Pubitemid 27420533)
    • (1997) Lancet , vol.350 , Issue.9082 , pp. 930-931
    • Pickar, D.1    Malhotra, A.K.2    Rooney, W.3    Breier, A.4    Goldman, D.5
  • 110
    • 0032194946 scopus 로고    scopus 로고
    • The apolipoprotein E epsilon4 allele is associated with blunting of ketamine-Induced psychosis in schizophrenia: A preliminary report
    • DOI 10.1016/S0893-133X(98)00031-1, PII S0893133X98000311
    • A. K. Malhotra, A. Breier, D. Goldman, L. Picken and D. Pickar: The apolipoprotein E epsilon 4 allele is associated with blunting of ketamine-induced psychosis in schizophrenia. A preliminary report. Neuropsychopharmacology, 19, 445-448 (1998) (Pubitemid 28451600)
    • (1998) Neuropsychopharmacology , vol.19 , Issue.5 , pp. 445-448
    • Malhotra, A.K.1    Breier, A.2    Goldman, D.3    Picken, L.4    Pickar, D.5
  • 112
    • 70049106107 scopus 로고    scopus 로고
    • Apolipoprotein e polymorphism and clinical disease phenotypes in Arab patients with schizophrenia
    • A. O. Akanji, J. U. Ohaeri, S. N. Al-Shammri and H. R. Fatania: Apolipoprotein E polymorphism and clinical disease phenotypes in Arab patients with schizophrenia. Neuropsychobiology, 60, 67-72 (2009)
    • (2009) Neuropsychobiology , vol.60 , pp. 67-72
    • Akanji, A.O.1    Ohaeri, J.U.2    Al-Shammri, S.N.3    Fatania, H.R.4
  • 114
    • 33646534632 scopus 로고    scopus 로고
    • Meta-analysis of association between ApoE epsilon4 allele and schizophrenia
    • M. Q. Xu, D. St Clair and L. He: Meta-analysis of association between ApoE epsilon4 allele and schizophrenia. Schizophr Res 84(2-3), 228-235 (2006)
    • (2006) Schizophr Res , vol.84 , Issue.2-3 , pp. 228-235
    • Xu, M.Q.1    St Clair, D.2    He, L.3
  • 116
    • 0033624682 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon3 allele is not a risk factor of schizophrenia: A study of 314 Japanese patients
    • T. Kimura, M. Shono, S. Yokota, R. Igata-Yi, J. Takamatsu and T. Miyakawa: Apolipoprotein E epsilon3 allele is not a risk factor of schizophrenia: a study of 314 Japanese patients. Neuropsychobiology, 42, 66-68 (2000) (Pubitemid 30665978)
    • (2000) Neuropsychobiology , vol.42 , Issue.2 , pp. 66-68
    • Kimura, T.1    Shono, M.2    Yokota, S.3    Igata-Yi, R.4    Takamatsu, J.5    Miyakawa, T.6
  • 119
    • 0034535991 scopus 로고    scopus 로고
    • Apolipoprotein E genotype in Spanish schizophrenic patients
    • N. Durany, P. Riederer and F. F. Cruz-Sanchez: Apolipoprotein E genotype in Spanish schizophrenic patients. Psychiatr Genet, 10, 73-77 (2000) (Pubitemid 32000903)
    • (2000) Psychiatric Genetics , vol.10 , Issue.2 , pp. 73-77
    • Durany, N.1    Riederer, P.2    Cruz-Sanchez, F.F.3
  • 125
    • 0037043789 scopus 로고    scopus 로고
    • Possible effect of the APOE epsilon 4 allele on the hippocampal volume and asymmetry in schizophrenia
    • T. Hata, H. Kunugi, S. Nanko, R. Fukuda and T. Kaminaga: Possible effect of the APOE epsilon 4 allele on the hippocampal volume and asymmetry in schizophrenia. Am J Med Genet, 114, 641-642 (2002)
    • (2002) Am J Med Genet , vol.114 , pp. 641-642
    • Hata, T.1    Kunugi, H.2    Nanko, S.3    Fukuda, R.4    Kaminaga, T.5
  • 127
    • 0345039180 scopus 로고    scopus 로고
    • The lipid hypothesis of schizophrenia
    • Ed E. R. Skinner. Elsevier Science, Amsterdam
    • D. Horrobin: The lipid hypothesis of schizophrenia. In: Brain Lipids and Disorders in Biological Psychiatry Ed E. R. Skinner. Elsevier Science, Amsterdam (2002)
    • (2002) Brain Lipids and Disorders in Biological Psychiatry
    • Horrobin, D.1
  • 128
    • 0030587415 scopus 로고    scopus 로고
    • Serum cholesterol and treatment-resistance in schizophrenia
    • DOI 10.1016/0006-3223(96)00102-3
    • P. F. Boston, S. M. Dursun, R. Zafar and M. A. Reveley: Serum cholesterol and treatment-resistance in schizophrenia. Biol Psychiatry, 40, 542-543 (1996) (Pubitemid 26319621)
    • (1996) Biological Psychiatry , vol.40 , Issue.6 , pp. 542-543
    • Boston, P.F.1    Dursun, S.M.2    Zafar, R.3    Reveley, M.A.4
  • 129
    • 79959583368 scopus 로고    scopus 로고
    • Apolipoprotein e and schizophrenia: Association with clinical response to clozapine
    • M. C. Royston, R. Bell, D. Collier, R. W. Kerwin and G. W. Roberts: Apolipoprotein E and schizophrenia: association with clinical response to clozapine. Schizophr Res, 24, 93-94 (1997)
    • (1997) Schizophr Res , vol.24 , pp. 93-94
    • Royston, M.C.1    Bell, R.2    Collier, D.3    Kerwin, R.W.4    Roberts, G.W.5
  • 130
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
    • DOI 10.1038/ng0996-55
    • M. Miyata and J. D. Smith: Apolipoprotein E allelespecific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nature Genet, 14, 55-61 (1996) (Pubitemid 26301547)
    • (1996) Nature Genetics , vol.14 , Issue.1 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 131
    • 0029923725 scopus 로고    scopus 로고
    • Free radical pathology and antioxidant defense in schizophrenia: A review
    • DOI 10.1016/0920-9964(95)00049-6
    • S. P. Mahadik and S. Mukherjee: Free radical pathology and antioxidant defense in schizophrenia: a review. Schizophr Res, 19, 1-17 (1996) (Pubitemid 26133208)
    • (1996) Schizophrenia Research , vol.19 , Issue.1 , pp. 1-17
    • Mahadik, S.P.1    Mukherjee, S.2
  • 133
    • 1342301694 scopus 로고    scopus 로고
    • Evidence for oxidative DNA damage in the hippocampus of elderly patients with chronic schizophrenia
    • DOI 10.1176/appi.ajgp.12.2.167
    • N. Nishioka and S. E. Arnold: Evidence for oxidative DNA damage in the hippocampus of elderly patients with chronic schizophrenia. Am J Geriatr Psychiatry, 12, 167-175 (2004) (Pubitemid 38250300)
    • (2004) American Journal of Geriatric Psychiatry , vol.12 , Issue.2 , pp. 167-175
    • Nishioka, N.1    Arnold, S.E.2
  • 135
    • 0028931917 scopus 로고
    • Plasma-soluble interleukin-2 and transferrin receptor in schizophrenia and major depression
    • M. Maes, H. Y. Meltzer, P. Buckley and E. Bosmans: Plasma-soluble interleukin-2 and transferrin receptor in schizophrenia and major depression. Eur Arch Psychiatry. Clin Neurosci, 244, 325-329 (1995)
    • (1995) Eur Arch Psychiatry. Clin Neurosci , vol.244 , pp. 325-329
    • Maes, M.1    Meltzer, H.Y.2    Buckley, P.3    Bosmans, E.4
  • 136
    • 33645746696 scopus 로고    scopus 로고
    • Apolipoprotein gene E4 allele promoter polymorphisms as risk factors for Alzheimer's disease
    • DOI 10.1097/00041444-200512000-00009, PII 0004144420051200000009
    • G. R. Parker, H. M. Cathcart, R. Huang, I. S. Lanham, E. H. Corder and S. E. Poduslo: Apolipoprotein gene E4 allele promoter polymorphisms as risk factors for Alzheimer's disease. Psychiatr Genet, 15, 271-275 (2005) (Pubitemid 44491465)
    • (2005) Psychiatric Genetics , vol.15 , Issue.4 , pp. 271-275
    • Parker, G.R.1    Cathcart, H.M.2    Huang, R.3    Lanham, I.S.4    Corder, E.H.5    Poduslo, S.E.6
  • 138
    • 0036382942 scopus 로고    scopus 로고
    • Variation at the APOE-491 promoter locus is associated with altered brain levels of apolipoprotein e
    • S. M. Laws, E. Hone, K. Taddei, C. Harper, B. Dean, C. McClean, C. Masters, N. Lautenschlager, S. E. Gandy and R. N. Martins: Variation at the APOE-491 promoter locus is associated with altered brain levels of apolipoprotein E. Mol Psychiatry, 7, 886-890 (2002)
    • (2002) Mol Psychiatry , vol.7 , pp. 886-890
    • Laws, S.M.1    Hone, E.2    Taddei, K.3    Harper, C.4    Dean, B.5    McClean, C.6    Masters, C.7
  • 139
    • 0032582781 scopus 로고    scopus 로고
    • Apolipoprotein E regulatory region genotype in schizophrenia
    • DOI 10.1016/S0304-3940(98)00761-7, PII S0304394098007617
    • T. Shinkai, O. Ohmori, H. Kojima, T. Terao, T. Suzuki, K. Abe and J. Nakamura: Apolipoprotein E regulatory region genotype in schizophrenia. Neurosci Lett, 256, 57-60 (1998) (Pubitemid 28535403)
    • (1998) Neuroscience Letters , vol.256 , Issue.1 , pp. 57-60
    • Shinkai, T.1    Ohmori, O.2    Kojima, H.3    Terao, T.4    Suzuki, T.5    Abe, K.6    Nakamura, J.7
  • 140
    • 16844379258 scopus 로고    scopus 로고
    • Differential changes in apolipoprotein E in schizophrenia and bipolar I disorder
    • DOI 10.1016/j.biopsych.2004.12.028
    • A. Digney, D. Keriakous, E. Scarr, E. Thomas and B. Dean: Differential changes in apolipoprotein E in schizophrenia and bipolar I disorder. Biol Psychiatr,y 57, 711-715 (2005) (Pubitemid 40487914)
    • (2005) Biological Psychiatry , vol.57 , Issue.7 , pp. 711-715
    • Digney, A.1    Keriakous, D.2    Scarr, E.3    Thomas, E.4    Dean, B.5
  • 141
    • 79959590961 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein and Apolipoprotein e expression is altered in schizophrenia
    • A. S. Gibbons, E. A. Thomas, E. Scarr and B. Dean: Low density lipoprotein receptor-related protein and Apolipoprotein E expression is altered in schizophrenia. Front Mol Psychiatry, 1, 19 (2010)
    • (2010) Front Mol Psychiatry , vol.1 , pp. 19
    • Gibbons, A.S.1    Thomas, E.A.2    Scarr, E.3    Dean, B.4
  • 142
    • 38749086806 scopus 로고    scopus 로고
    • Plasma apolipoprotein e is decreased in schizophrenia spectrum and bipolar disorder
    • B. Dean, A. Digney, S. Sundram, E. Thomas and E. Scarr: Plasma apolipoprotein E is decreased in schizophrenia spectrum and bipolar disorder. Psychiatry Res, 158, 75-78 (2008)
    • (2008) Psychiatry Res , vol.158 , pp. 75-78
    • Dean, B.1    Digney, A.2    Sundram, S.3    Thomas, E.4    Scarr, E.5
  • 143
    • 30344446650 scopus 로고    scopus 로고
    • Decreasing myelin density reflected increasing white matter pathology in azheimer's disease - A neuropathological study
    • DOI 10.1002/gps.1384
    • M. Sjobeck, M. Haglund and E. Englund: Decreasing myelin density reflected increasing white matter pathology in Alzheimer's disease - a neuropathological study. Int J Geriatr Psychiatry, 20, 919-926 (2005) (Pubitemid 43055103)
    • (2005) International Journal of Geriatric Psychiatry , vol.20 , Issue.10 , pp. 919-926
    • Sjobeck, M.1    Haglund, M.2    Englund, E.3
  • 144
    • 36549071668 scopus 로고    scopus 로고
    • Apolipoprotein E Affects Both Myelin Breakdown and Cognition: Implications for Age-Related Trajectories of Decline Into Dementia
    • DOI 10.1016/j.biopsych.2007.03.024, PII S0006322307003186
    • G. Bartzokis, P. H. Lu, D. H. Geschwind, K. Tingus, D. Huang, M. F. Mendez, N. Edwards and J. Mintz: Apolipoprotein e affects both myelin breakdown and cognition: Implications for age-related trajectories of decline into dementia. Biol Psychiatry, 62, 1380-1387 (2007) (Pubitemid 350180726)
    • (2007) Biological Psychiatry , vol.62 , Issue.12 , pp. 1380-1387
    • Bartzokis, G.1    Lu, P.H.2    Geschwind, D.H.3    Tingus, K.4    Huang, D.5    Mendez, M.F.6    Edwards, N.7    Mintz, J.8
  • 146
    • 1342300634 scopus 로고    scopus 로고
    • Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: A study from the Stanley Neuropathology Consortium
    • DOI 10.1016/S0920-9964(03)00181-6
    • N. A. Uranova, V. M. Vostrikov, D. D. Orlovskaya and V. I. Rachmanova: Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium. Schizophr Res, 67, 269-275 (2004) (Pubitemid 38251458)
    • (2004) Schizophrenia Research , vol.67 , Issue.2-3 , pp. 269-275
    • Uranova, N.A.1    Vostrikov, V.M.2    Orlovskaya, D.D.3    Rachmanova, V.I.4
  • 148
    • 0025946238 scopus 로고
    • Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing Apolipoprotein-E
    • J. F. Goodrum: Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing Apolipoprotein-E. J Neurochem, 56, 2082-2086 (1991)
    • (1991) J Neurochem , vol.56 , pp. 2082-2086
    • Goodrum, J.F.1
  • 149
    • 0036844074 scopus 로고    scopus 로고
    • Association analysis of polymorphic CGG repeat in 5' UTR of the reelin and VLDLR genes with schizophrenia
    • DOI 10.1016/S0920-9964(01)00398-X, PII S092099640100398X
    • A. Akahane, H. Kunugi, H. Tanaka and S. Nanko: Association analysis of polymorphic CGG repeat in 5' UTR of the reelin and VLDLR genes with schizophrenia. Schizophr Res,58, 37-41 (2002) (Pubitemid 35287281)
    • (2002) Schizophrenia Research , vol.58 , Issue.1 , pp. 37-41
    • Akahane, A.1    Kunugi, H.2    Tanaka, H.3    Nanko, S.4
  • 152
    • 0028940096 scopus 로고
    • A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
    • G. D'Arcangelo, G. G. Miao, S. C. Chen, H. D. Soares, J. I. Morgan and T. Curran: A protein related to extracellular matrix proteins deleted in the mouse mutant reeler. Nature, 374, 719-723 (1995)
    • (1995) Nature , vol.374 , pp. 719-723
    • D'Arcangelo, G.1    Miao, G.G.2    Chen, S.C.3    Soares, H.D.4    Morgan, J.I.5    Curran, T.6
  • 153
    • 0018640776 scopus 로고
    • An early developmental defect in the cerebral cortex of the reeler mouse. A morphological study leading to a hypothesis concerning the action of the mutant gene
    • DOI 10.1007/BF00305160
    • A. M. Goffinet: An early development defect in the cerebral cortex of the reeler mouse. A morphological study leading to a hypothesis concerning the action of the mutant gene. Anat Embryol (Berl), 157, 205-216 (1979) (Pubitemid 10192068)
    • (1979) Anatomy and Embryology , vol.157 , Issue.2 , pp. 205-216
    • Goffinet, A.M.1
  • 154
    • 0029008666 scopus 로고
    • The reeler geneassociated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons
    • M. Ogawa, T. Miyata, K. Nakajima, K. Yagyu, M. Seike, K. Ikenaka, H. Yamamoto and K. Mikoshiba: The reeler geneassociated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron, 14, 899-912 (1995)
    • (1995) Neuron , vol.14 , pp. 899-912
    • Ogawa, M.1    Miyata, T.2    Nakajima, K.3    Yagyu, K.4    Seike, M.5    Ikenaka, K.6    Yamamoto, H.7    Mikoshiba, K.8
  • 155
    • 28944440029 scopus 로고    scopus 로고
    • A fresh look at an ancient receptor family: Emerging roles for low density lipoprotein receptors in synaptic plasticity and memory formation
    • DOI 10.1016/j.nlm.2005.08.009, PII S1074742705000766
    • S. Qiu, K. M. Korwek and E. J. Weeber: A fresh look at an ancient receptor family: emerging roles for low density lipoprotein receptors in synaptic plasticity and memory formation. Neurobiol Learn Mem, 85, 16-29 (2006) (Pubitemid 41786046)
    • (2006) Neurobiology of Learning and Memory , vol.85 , Issue.1 , pp. 16-29
    • Qiu, S.1    Korwek, K.M.2    Weeber, E.J.3
  • 156
    • 33750333569 scopus 로고    scopus 로고
    • Reelin, lipoprotein receptors and synaptic plasticity
    • DOI 10.1038/nrn2009, PII NRN2009
    • J. Herz and Y. Chen: Reelin, lipoprotein receptors and synaptic plasticity. Nature Rev Neurosci, 7, 850-859 (2006) (Pubitemid 44624177)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.11 , pp. 850-859
    • Herz, J.1    Chen, Y.2
  • 158
    • 33645900258 scopus 로고    scopus 로고
    • Cellular basis of reduced cortical reelin expression in schizophrenia
    • DOI 10.1176/appi.ajp.163.3.540
    • S. L. Eastwood and P. J. Harrison: Cellular basis of reduced cortical reelin expression in schizophrenia. Am J Psychiatry, 163, 540-542 (2006) (Pubitemid 44469402)
    • (2006) American Journal of Psychiatry , vol.163 , Issue.3 , pp. 540-542
    • Eastwood, S.L.1    Harrison, P.J.2
  • 159
    • 0033646608 scopus 로고    scopus 로고
    • Reduction in reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression
    • S. H. Fatemi, J. A. Earle and T. McMenomy: Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. Mol Psychiatry, 5, 654-663 (2000)
    • (2000) Mol Psychiatry , vol.5 , pp. 654-663
    • Fatemi, S.H.1    Earle, J.A.2    McMenomy, T.3
  • 161
    • 13244255518 scopus 로고    scopus 로고
    • Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains
    • DOI 10.1016/j.biopsych.2004.10.019, PII S0006322304010996
    • E. F. Torrey, B. M. Barci, M. J. Webster, J. J. Bartko, J. H. Meador-Woodruff and M. B. Knable: Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains. Biol Psychiatry, 57, 252-260 (2005) (Pubitemid 40187369)
    • (2005) Biological Psychiatry , vol.57 , Issue.3 , pp. 252-260
    • Torrey, E.F.1    Barci, B.M.2    Webster, M.J.3    Bartko, J.J.4    Meador-Woodruff, J.H.5    Knable, M.B.6
  • 163
    • 0037414405 scopus 로고    scopus 로고
    • Olfactory discrimination learning deficit in heterozygous reeler mice
    • DOI 10.1016/S0006-8993(03)02353-9
    • J. Larson, J. S. Hoffman, A. Guidotti and E. Costa: Olfactory discrimination learning deficit in heterozygous reeler mice. Brain Res, 971, 40-46 (2003) (Pubitemid 36412062)
    • (2003) Brain Research , vol.971 , Issue.1 , pp. 40-46
    • Larson, J.1    Hoffman, J.S.2    Guidotti, A.3    Costa, E.4
  • 167
    • 0032078508 scopus 로고    scopus 로고
    • Role of Reelin in the control of brain development
    • DOI 10.1016/S0165-0173(97)00035-0, PII S0165017397000350
    • T. Curran and G. D'Arcangelo: Role of reelin in the control of brain development. Brain Res. Brain Res Rev 26, 285-294 (1998) (Pubitemid 28318083)
    • (1998) Brain Research Reviews , vol.26 , Issue.2-3 , pp. 285-294
    • Curran, T.1    D'Arcangelo, G.2
  • 168
    • 0033003134 scopus 로고    scopus 로고
    • Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
    • DOI 10.1016/S0092-8674(00)80782-5
    • M. Trommsdorff, M. Gotthardt, T. Hiesberger, J. Shelton, W. Stockinger, J. Nimpf, R. E. Hammer, J. A. Richardson and J. Herz: Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell, 97, 689-701 (1999) (Pubitemid 29278044)
    • (1999) Cell , vol.97 , Issue.6 , pp. 689-701
    • Trommsdorff, M.1    Gotthardt, M.2    Hiesberger, T.3    Shelton, J.4    Stockinger, W.5    Nimpf, J.6    Hammer, R.E.7    Richardson, J.A.8    Herz, J.9
  • 169
    • 33646757886 scopus 로고    scopus 로고
    • The human reelin gene: Transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia
    • DOI 10.1016/j.pharmthera.2005.01.007, PII S0163725806000106
    • D. R. Grayson, Y. Chen, E. Costa, E. Dong, A. Guidotti, M. Kundakovic and R. P. Sharma: The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacol Therapy, 111, 272-286 (2006) (Pubitemid 43765535)
    • (2006) Pharmacology and Therapeutics , vol.111 , Issue.1 , pp. 272-286
    • Grayson, D.R.1    Chen, Y.2    Costa, E.3    Dong, E.4    Guidotti, A.5    Kundakovic, M.6    Sharma, R.P.7
  • 174
    • 0035968886 scopus 로고    scopus 로고
    • Altered levels of Reelin and its isoforms in schizophrenia and mood disorders
    • S. H. Fatemi, J. L. Kroll and J. M. Stary: Altered levels of Reelin and its isoforms in schizophrenia and mood disorders. Neuroreport 12, 3209-3215 (2001) (Pubitemid 33010645)
    • (2001) NeuroReport , vol.12 , Issue.15 , pp. 3209-3215
    • Fatemi, S.H.1    Kroll, J.L.2    Stary, J.M.3
  • 175
    • 0033556876 scopus 로고    scopus 로고
    • Apolipoprotein E-epsilon4 frequency in affective disorder
    • DOI 10.1016/S0006-3223(98)00038-9, PII S0006322398000389
    • L. V. Kessing and O. S. Jørgensen: Apolipoprotein E-[varepsilon]4 frequency in affective disorder. Biol Psychiatry, 45, 430-434 (1999) (Pubitemid 29130441)
    • (1999) Biological Psychiatry , vol.45 , Issue.4 , pp. 430-434
    • Kessing, L.V.1    Jorgensen, O.S.2
  • 177
    • 0346463242 scopus 로고    scopus 로고
    • Association between Apolipoprotein E epsilon4 and Neuropsychiatric Symptoms during Interferon alpha Treatment for Chronic Hepatitis C
    • DOI 10.1176/appi.psy.45.1.49
    • P. A. Gochee, E. E. Powell, D. M. Purdie, N. Pandeya, L. Kelemen, C. Shorthouse, J. R. Jonsson and B. Kelly: Association Between Apolipoprotein E {epsilon}4 and Neuropsychiatric Symptoms During Interferon α Treatment for Chronic Hepatitis C. Psychosomatics, 45, 49-57 (2004) (Pubitemid 38082507)
    • (2004) Psychosomatics , vol.45 , Issue.1 , pp. 49-57
    • Gochee, P.A.1    Powell, E.E.2    Purdie, D.M.3    Pandeya, N.4    Kelemen, L.5    Shorthouse, C.6    Jonsson, J.R.7    Kelly, B.8
  • 178
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
    • DOI 10.1038/ng0996-55
    • M. Miyata and J. D. Smith: Apolipoprotein E allelespecific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nature Genet, 14, 55-61 (1996) (Pubitemid 26301547)
    • (1996) Nature Genetics , vol.14 , Issue.1 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 179
    • 33644779105 scopus 로고    scopus 로고
    • Protective effect of the apo e2 allele in major depressive disorder in Taiwanese
    • P. L. Fan, C. D. Chen, W. T. Kao, B. C. Shu and F. W. Lung: Protective effect of the apo e2 allele in major depressive disorder in Taiwanese. Acta Psychiatr Scand, 113, 48-53 (2006)
    • (2006) Acta Psychiatr Scand , vol.113 , pp. 48-53
    • Fan, P.L.1    Chen, C.D.2    Kao, W.T.3    Shu, B.C.4    Lung, F.W.5
  • 181
    • 16844379258 scopus 로고    scopus 로고
    • Differential changes in apolipoprotein E in schizophrenia and bipolar I disorder
    • DOI 10.1016/j.biopsych.2004.12.028
    • A. Digney, D. Keriakous, E. Scarr, E. Thomas and B. Dean: Differential changes in apolipoprotein E in schizophrenia and bipolar I disorder. Biol Psychiatry, 57, 711-715 (2005) (Pubitemid 40487914)
    • (2005) Biological Psychiatry , vol.57 , Issue.7 , pp. 711-715
    • Digney, A.1    Keriakous, D.2    Scarr, E.3    Thomas, E.4    Dean, B.5
  • 182
    • 38749086806 scopus 로고    scopus 로고
    • Plasma apolipoprotein e is decreased in schizophrenia spectrum and bipolar disorder
    • B. Dean, A. Digney, S. Sundram, E. Thomas and E. Scarr: Plasma apolipoprotein E is decreased in schizophrenia spectrum and bipolar disorder. Psychiatry Res 158(1), 75-78 (2008)
    • (2008) Psychiatry Res , vol.158 , Issue.1 , pp. 75-78
    • Dean, B.1    Digney, A.2    Sundram, S.3    Thomas, E.4    Scarr, E.5
  • 183
    • 36549029252 scopus 로고    scopus 로고
    • Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder
    • DOI 10.1038/sj.npp.1301575, PII 1301575
    • R. J. Schloesser, J. Huang, P. S. Klein and H. K. Manji: Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology, 33, 110-133 (2008) (Pubitemid 350191320)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.1 , pp. 110-133
    • Schloesser, R.J.1    Huang, J.2    Klein, P.S.3    Manji, H.K.4
  • 184
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • DOI 10.1038/sj.npp.1301574, PII 1301574
    • C. Pittenger and R. S. Duman: Stress, depression, and neuroplasticity: A convergence of mechanisms. Neuropsychopharmacology, 33, 88-109 (2008) (Pubitemid 350191319)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.1 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 185
    • 24144481492 scopus 로고    scopus 로고
    • Schizophrenia and comorbid metabolic disorders
    • D. C. Henderson: Schizophrenia and comorbid metabolic disorders. J Clin Psychiatry, 66 Suppl, 11-20 (2005) (Pubitemid 41243257)
    • (2005) Journal of Clinical Psychiatry , vol.66 , Issue.SUPPL. 6 , pp. 11-20
    • Henderson, D.C.1
  • 186
    • 75349110746 scopus 로고    scopus 로고
    • Metabolic syndrome: A follow-up study of acute depressive inpatients
    • N. Richter, G. Juckel and H. J. Assion: Metabolic syndrome: a follow-up study of acute depressive inpatients. Eur Arch Psychiatry. Clin Neurosci, 260, 41-49 (2009)
    • (2009) Eur Arch Psychiatry. Clin Neurosci , vol.260 , pp. 41-49
    • Richter, N.1    Juckel, G.2    Assion, H.J.3
  • 187
    • 0347596648 scopus 로고    scopus 로고
    • Obesity as a risk factor for antipsychotic noncompliance
    • DOI 10.1016/S0920-9964(02)00498-X
    • P. J. Weiden, J. A. Mackell and D. D. McDonnell: Obesity as a risk factor for antipsychotic noncompliance. Schizophr Res 66, 51-57 (2004) (Pubitemid 38030344)
    • (2004) Schizophrenia Research , vol.66 , Issue.1 , pp. 51-57
    • Weiden, P.J.1    Mackell, J.A.2    McDonnell, D.D.3
  • 189
    • 34548555885 scopus 로고    scopus 로고
    • Apolipoprotein E polymorphism - A risk factor for metabolic syndrome
    • DOI 10.1515/CCLM.2007.258
    • A. Sima, A. Iordan and C. Stancu: Apolipoprotein E polymorphism - a risk factor for metabolic syndrome. Clin Chem Lab Med 45, 1149-1153 (2007) (Pubitemid 47396270)
    • (2007) Clinical Chemistry and Laboratory Medicine , vol.45 , Issue.9 , pp. 1149-1153
    • Sima, A.1    Iordan, A.2    Stancu, C.3
  • 190
    • 70449658181 scopus 로고    scopus 로고
    • Relationship between the diagnostic components of metabolic syndrome (MS) and cognition by ApoE genotype in the elderly
    • K. S. Lee, Y. Jang, Y.-K. Chung, J. H. Chung, B. H. Oh and C. H. Hong: Relationship between the diagnostic components of metabolic syndrome (MS) and cognition by ApoE genotype in the elderly. Arch Gerontol Geriatr, 50, 69-72 (2009)
    • (2009) Arch Gerontol Geriatr , vol.50 , pp. 69-72
    • Lee, K.S.1    Jang, Y.2    Chung, Y.-K.3    Chung, J.H.4    Oh, B.H.5    Hong, C.H.6
  • 191
    • 16644365958 scopus 로고    scopus 로고
    • Dyslipidemia and atypical antipsychotic drugs
    • D. E. Casey: Dyslipidemia and atypical antipsychotic drugs. J Clin Psychiatry, 65, 27-35 (2004)
    • (2004) J Clin Psychiatry , vol.65 , pp. 27-35
    • Casey, D.E.1
  • 192
    • 0029967145 scopus 로고    scopus 로고
    • Bodyweight change as an adverse effect of drug treatment - Mechanisms and management
    • H. Pijl and A. E. Meinders: Bodyweight change as an adverse effect of drug treatment - Mechanisms and management. Drug Safety 14, 329-342 (1996)
    • (1996) Drug Safety , vol.14 , pp. 329-342
    • Pijl, H.1    Meinders, A.E.2
  • 194
    • 0035024729 scopus 로고    scopus 로고
    • Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone
    • B. R. Basson, B. J. Kinon, C. C. Taylor, K. A. Szymanski, J. A. Gilmore and G. D. Tollefson: Factors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidone. J Clini Psychiatry, 62, 231-238 (2001) (Pubitemid 32428761)
    • (2001) Journal of Clinical Psychiatry , vol.62 , Issue.4 , pp. 231-238
    • Basson, B.R.1    Kinon, B.J.2    Taylor, C.C.3    Szymanski, K.A.4    Gilmore, J.A.5    Tollefson, G.D.6
  • 195
    • 68049122005 scopus 로고    scopus 로고
    • Metabolic risk factors in drug-naive patients with first-episode psychosis
    • S. K. Verma, M. Subramaniam, A. Liew and L. Y. Poon: Metabolic Risk Factors in Drug-Naive Patients With First-Episode Psychosis. J Clin Psychiatry, 70, 997-1000 (2009)
    • (2009) J Clin Psychiatry , vol.70 , pp. 997-1000
    • Verma, S.K.1    Subramaniam, M.2    Liew, A.3    Poon, L.Y.4
  • 196
    • 61749104614 scopus 로고    scopus 로고
    • Factors associated with non-use of antipsychotics among older residents with schizophrenia in long-term institutional care
    • H.-M. Alanen, H. Finne-Soveri and E. Leinonen: Factors associated with non-use of antipsychotics among older residents with schizophrenia in long-term institutional care. Int J Geriatr Psychiatry, 23, 1261-1265 (2008)
    • (2008) Int J Geriatr Psychiatry , vol.23 , pp. 1261-1265
    • Alanen, H.-M.1    Finne-Soveri, H.2    Leinonen, E.3
  • 197
    • 35148870582 scopus 로고    scopus 로고
    • Height and body mass index in young adulthood and risk of schizophrenia: A longitudinal study of 1 347 520 Swedish men
    • DOI 10.1111/j.1600-0447.2007.01063.x
    • S. Zammit, F. Rasmussen, B. Farahmand, D. Gunnell, G. Lewis, P. Tynelius and G. P. Brobert: Height and body mass index in young adulthood and risk of schizophrenia: a longitudinal study of 1 347 520 Swedish men. Acta Psychiatr Scand 116(5), 378-385 (2007) (Pubitemid 47537422)
    • (2007) Acta Psychiatrica Scandinavica , vol.116 , Issue.5 , pp. 378-385
    • Zammit, S.1    Rasmussen, F.2    Farahmand, B.3    Gunnell, D.4    Lewis, G.5    Tynelius, P.6    Brobert, G.P.7
  • 198
    • 34249060050 scopus 로고    scopus 로고
    • Is dietary pattern of schizophrenia patients different from healthy subjects?
    • R. Amani: Is dietary pattern of schizophrenia patients different from healthy subjects? BMC Psychiatry 7, 15 (2007)
    • (2007) BMC Psychiatry , vol.7 , pp. 15
    • Amani, R.1
  • 199
    • 34547621628 scopus 로고    scopus 로고
    • Nutrition and exercise behavior among patients with bipolar disorder
    • DOI 10.1111/j.1399-5618.2007.00386.x
    • A. M. Kilbourne, D. L. Rofey, J. F. McCarthy, E. P. Post, D. Welsh and F. C. Blow: Nutrition and exercise behavior among patients with bipolar disorder. Bipolar Disord, 9, 443-452 (2007) (Pubitemid 47202506)
    • (2007) Bipolar Disorders , vol.9 , Issue.5 , pp. 443-452
    • Kilbourne, A.M.1    Rofey, D.L.2    Mccarthy, J.F.3    Post, E.P.4    Welsh, D.5    Blow, F.C.6
  • 200
    • 0033672209 scopus 로고    scopus 로고
    • Association study of apolipoprotein e epsilon4 with clinical phenotype and clozapine response in schizophrenia
    • C. J. Hong, Y. W. Yu, C. H. Lin, H. L. Song, H. C. Lai, K. H. Yang and S. J. Tsai: Association study of apolipoprotein E epsilon4 with clinical phenotype and clozapine response in schizophrenia. Neuropsychobiology, 42(4), 172-174 (2000)
    • (2000) Neuropsychobiology , vol.42 , Issue.4 , pp. 172-174
    • Hong, C.J.1    Yu, Y.W.2    Lin, C.H.3    Song, H.L.4    Lai, H.C.5    Yang, K.H.6    Tsai, S.J.7
  • 201
    • 0142040221 scopus 로고    scopus 로고
    • The apolipoprotein E epsilon4 allele and antidepressant efficacy in cognitively intact elderly depressed patients
    • DOI 10.1016/S0006-3223(03)00174-4
    • G. M. Murphy, C. Kremer, H. Rodrigues, A. F. Schatzberg and S. Mirtazapine versus Paroxetine: The apolipoprotein E epsilon 4 allele and antidepressant efficacy in cognitively intact elderly depressed patients. Biol Psychiatry, 54, 665-673 (2003) (Pubitemid 37281381)
    • (2003) Biological Psychiatry , vol.54 , Issue.7 , pp. 665-673
    • Murphy Jr., G.M.1    Kremer, C.2    Rodrigues, H.3    Schatzberg, A.F.4
  • 202
    • 70350060193 scopus 로고    scopus 로고
    • Apolipoprotein-E gene variants associated with cardiovascular risk factors in antipsychotic recipients
    • D. Clark, O. A. Skrobot, I. Adebiyi, M. T. Susce, J. de Leon, A. F. Blakemore and M. J. Arranz: Apolipoprotein-E gene variants associated with cardiovascular risk factors in antipsychotic recipients. Eur Psychiatry, 24, 456-463 (2009)
    • (2009) Eur Psychiatry , vol.24 , pp. 456-463
    • Clark, D.1    Skrobot, O.A.2    Adebiyi, I.3    Susce, M.T.4    De Leon, J.5    Blakemore, A.F.6    Arranz, M.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.