Growth arrest of solid human neuroblastoma xenografts in nude rats by natural IgM from healthy humans

Nature Medicine

Volumn 2, Issue 6, 1996, Pages 686-689

  David, Kerstin ^a   Ollert, Markus W ^a   Juhl, Hartmut ^b   Vollmert, Caren ^a   Erttmann, Rudolf ^c   Vogel, Carl Wilhelm ^a   Bredehorst, Reinhard ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER IMMUNOTHERAPY; CANCER INHIBITION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; XENOGRAFT;

ADULT; ANIMALS; FEMALE; HUMANS; IMMUNOGLOBULIN M; MALE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NEUROBLASTOMA; NEUTROPHILS; RATS; RATS, NUDE; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA;

EID: 0029894136     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0696-686     Document Type: Article

References (17)

1. Siegel, S.E. & Sato, J.K. Neuroblastoma. in Oncology, (eds. Moossa, A.R., Robson, M.C. & Schimpfl, S.C.) 1211-1231 (Williams & Wilkins, Baltimore, 1986).
2. Pinkerton, C.R. Neuroblastoma in the 1990s. A clinical perspective. in Human Neuroblastoma: Recent Advances in Clinical and Genetic Analysis, (eds. Schwab, M., Tonini, G.P. & Bénard, J.) 3-10 (Harwood Academic Publ., Chur, Switzerland, 1993).
3. Philip, T. & Pinkerton, R. Neuroblastoma. in New Directions in Cancer Treatment. (ed. Magrath, J.) 605-611 (Springer, Heidelberg, Germany, 1989).
4. Ollert, M.W. et al. Normal human serum contains a natural IgM antibody cytotoxic for human neuroblastoma cells. Proc. Natl. Acad. Sci. U.S.A. (in the press).
5. Dixon, F.J., Vasquez, J.J., Weigle, W.O. & Cochrane, C.G. Pathogenesis of serum sickness. Arch. Pathol. 65, 18-25 (1958).
6. Handgretinger, R. et al. The possible role of granulocytes in the therapy of neuroblastoma. in Human Neuroblastoma: Recent Advances in Clinical and Genetic Analysis. (eds. Schwab, M., Tonini, G.P. & Bénard, J.) 24-33 (Harwood Academic Publishers, Chur, Switzerland, 1993).
7. Bruchelt, G. et al. Effect of granulocytes on human neuroblastoma cells measured by chemiluminescence and chromium-51 release assay. J. Biolumin. Chemilumin. 3, 93-96 (1989).
8. Barker, E. et al. Effect of a chimeric anti-ganglioside GD2 antibody on cell-mediated lysis of human neuroblastoma cells. Cancer Res. 51, 144-149 (1991).
9. Barker, E. & Reisfeld, R.A. A mechanism for neutrophil-mediated lysis of human neuroblastoma cells. Cancer Res. 53, 362-367 (1993).
10. Kushner, B.H. & Cheung, N.-K.V. GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma. Blood 73, 1936-1941 (1989).
11. Savill, J., Fadok, V., Henson, P. & Haslett, C. Phagocyte recognition of cells undergoing apoptosis. Immunol. Today 14, 131-136 (1993).
12. Ouchterlony, Ö. & Nilsson, L.-Å. Immunodiffusion and immunoelectrophoresis. in Handbook of Experimental Immunology: Immunochemistry. 19.1-19.44 (ed. Weir, D.M.) (Blackwell Scientific Publ., Oxford, UK, 1978).
13. Vogel, C.-W. & Müller-Eberhard, H.J. Cobra venom factor: Improved method for purification and biochemical characterization. J. Immunol. Meth. 73, 203-220 (1984).
14. Juhl, H. et al. A monoclonal antibody-cobra venom factor conjugate increases the tumor-specific uptake of a 99mTc-anti-CEA antibody by a two-step approach. Cancer Res. 55, 5749s-5755s (1995).
15. Mujoo, K. et al. Functional properties and effect on growth suppression of human neuroblastoma tumors by isotype switch variants of monoclonal antiganglioside GD2 antibody 14.18. Cancer Res. 49, 2857-2861 (1989).
16. Burck, H.-C. Physikalische und physikochemische Färbemethoden. in Histologische Technik. 104-141 (Georg Thieme, Stuttgart, Germany, 1988).
17. Laemmli, U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).