Gene transfer of the adaptor Lnk (SH2B3) prevents porcine endothelial cell activation and apoptosis: Implication for xenograft's cytoprotection

Xenotransplantation

Volumn 18, Issue 2, 2011, Pages 108-120

  Chatelais, Mathias ^a,b,c   Devallière, Julie ^a,b,c   Galli, Cesare ^d,e   Charreau, Béatrice ^a,b,c  

^a HÔTEL DIEU   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE NANTES   (France)

^d Laboratorio di Tecnologie della Riproduzione   (Italy)

^e UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

adaptor protein; apoptosis; endothelial cells; inflammation; Lnk (SH2B3); xenotransplantation

Indexed keywords

ADAPTOR PROTEIN; CASPASE 3; CASPASE 7; COMPLEMENT MEMBRANE ATTACK COMPLEX; DACTINOMYCIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LNK PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANOIKIS; ANTIGEN BINDING; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DEATH; CELL PROTECTION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA CONTENT; ENDOTHELIUM CELL; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION; GENE TRANSFER; INFLAMMATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECOMBINANT ADENOVIRUS; SIGNAL TRANSDUCTION; SWINE; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; WESTERN BLOTTING; WILD TYPE; XENOGRAFT; XENOTRANSPLANTATION;

ADENOVIRIDAE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANOIKIS; APOPTOSIS; CELLS, CULTURED; CYTOPROTECTION; ENDOTHELIUM, VASCULAR; GALACTOSYLTRANSFERASES; GENE KNOCKOUT TECHNIQUES; HUMANS; INFLAMMATION; PROTEINS; SIGNAL TRANSDUCTION; SWINE; TRANSDUCTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 79954998464     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2011.00629.x     Document Type: Article

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