메뉴 건너뛰기




Volumn 107, Issue 7, 2006, Pages 2968-2975

Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL ADHESION MOLECULE; MUTANT PROTEIN; VASCULAR ADHESION PROTEIN 1;

EID: 33645509876     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-05-2138     Document Type: Article
Times cited : (39)

References (43)
  • 2
    • 0034959561 scopus 로고    scopus 로고
    • Persistent low-level engraftment of rhesus peripheral blood progenitor cells transduced with the fanconi anemia C gene after conditioning with low-dose irradiation
    • Kang EM, Hanazano Y, Frare P, et al. Persistent low-level engraftment of rhesus peripheral blood progenitor cells transduced with the fanconi anemia C gene after conditioning with low-dose irradiation. Mol Ther. 2001;3:911-919.
    • (2001) Mol Ther , vol.3 , pp. 911-919
    • Kang, E.M.1    Hanazano, Y.2    Frare, P.3
  • 3
    • 0037134031 scopus 로고    scopus 로고
    • Murine leukemia induced by retroviral gene marking
    • Li Z, Dullmann J, Schiedlmeier B, et al. Murine leukemia induced by retroviral gene marking. Science. 2002;296:497.
    • (2002) Science , vol.296 , pp. 497
    • Li, Z.1    Dullmann, J.2    Schiedlmeier, B.3
  • 4
    • 0037057620 scopus 로고    scopus 로고
    • Regulators split on gene therapy as patient shows signs of cancer
    • Check E. Regulators split on gene therapy as patient shows signs of cancer. Nature. 2002;419:545-546.
    • (2002) Nature , vol.419 , pp. 545-546
    • Check, E.1
  • 5
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science. 2003;302:415-419.
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1    Von Kalle, C.2    Schmidt, M.3
  • 6
    • 0037443457 scopus 로고    scopus 로고
    • Side effects of retroviral gene transfer into hematopoietic stem cells
    • Baum C, Dullmann J, Li Z, et al. Side effects of retroviral gene transfer into hematopoietic stem cells. Blood. 2003;101:2099-2114.
    • (2003) Blood , vol.101 , pp. 2099-2114
    • Baum, C.1    Dullmann, J.2    Li, Z.3
  • 7
    • 0027484275 scopus 로고
    • Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin
    • U S A
    • Papayannopoulou T, Nakamoto B. Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin. Proc Natl Acad Sci U S A. 1993;90:9374-9378.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 9374-9378
    • Papayannopoulou, T.1    Nakamoto, B.2
  • 8
    • 0028971211 scopus 로고
    • The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen
    • U S A
    • Papayannopoulou T, Craddock C, Nakamoto B, Priestley GV, Wolf NS. The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen. Proc Natl Acad Sci U S A. 1995;92:9647-9651.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 9647-9651
    • Papayannopoulou, T.1    Craddock, C.2    Nakamoto, B.3    Priestley, G.V.4    Wolf, N.S.5
  • 9
    • 4644284957 scopus 로고    scopus 로고
    • Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation
    • Katayama Y, Hidalgo A, Peired A, Frenette PS. Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation. Blood. 2004;104:2020-2026.
    • (2004) Blood , vol.104 , pp. 2020-2026
    • Katayama, Y.1    Hidalgo, A.2    Peired, A.3    Frenette, P.S.4
  • 10
    • 0030604540 scopus 로고    scopus 로고
    • Differential requirements for alpha4 integrins during fetal and adult hematopoiesis
    • Arroyo AG, Yang JT, Rayburn H, Hynes RO. Differential requirements for alpha4 integrins during fetal and adult hematopoiesis. Cell. 1996;85:997-1008.
    • (1996) Cell , vol.85 , pp. 997-1008
    • Arroyo, A.G.1    Yang, J.T.2    Rayburn, H.3    Hynes, R.O.4
  • 11
    • 0033216389 scopus 로고    scopus 로고
    • Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo
    • Arroyo AG, Yang JT, Rayburn H, Hynes RO. Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo. Immunity. 1999;11:555-566.
    • (1999) Immunity , vol.11 , pp. 555-566
    • Arroyo, A.G.1    Yang, J.T.2    Rayburn, H.3    Hynes, R.O.4
  • 12
    • 0029758113 scopus 로고    scopus 로고
    • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
    • Nagasawa T, Hirota S, Tachibana K, et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 1996;382:635-638.
    • (1996) Nature , vol.382 , pp. 635-638
    • Nagasawa, T.1    Hirota, S.2    Tachibana, K.3
  • 13
    • 0032482926 scopus 로고    scopus 로고
    • Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4-and SDF-1-deficient mice
    • U S A
    • Ma Q, Jones D, Borghesani PR, Segal RA, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4-and SDF-1-deficient mice. Proc Natl Acad Sci U S A. 1998;95:9448-9453.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 9448-9453
    • Ma, Q.1    Jones, D.2    Borghesani, P.R.3    Segal, R.A.4
  • 14
    • 0037029654 scopus 로고    scopus 로고
    • Hematopoietic stem cells are uniquely selective in their migratory response to chemokines
    • Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med. 2002;195:1145-1154.
    • (2002) J Exp Med , vol.195 , pp. 1145-1154
    • Wright, D.E.1    Bowman, E.P.2    Wagers, A.J.3    Butcher, E.C.4    Weissman, I.L.5
  • 15
    • 11144356195 scopus 로고    scopus 로고
    • Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation
    • Kahn J, Byk T, Jansson-Sjostrand L, et al. Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation. Blood. 2004;103:2942-2949.
    • (2004) Blood , vol.103 , pp. 2942-2949
    • Kahn, J.1    Byk, T.2    Jansson-Sjostrand, L.3
  • 16
    • 0030992486 scopus 로고    scopus 로고
    • Characterization of Lnk. An adaptor protein expressed in lymphocytes
    • Takaki S, Watts JD, Forbush KA, et al. Characterization of Lnk. An adaptor protein expressed in lymphocytes. J Biol Chem. 1997;272:14562-14570.
    • (1997) J Biol Chem , vol.272 , pp. 14562-14570
    • Takaki, S.1    Watts, J.D.2    Forbush, K.A.3
  • 17
    • 0037148516 scopus 로고    scopus 로고
    • Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk
    • Takaki S, Morita H, Tezuka Y, Takatsu K. Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk. J Exp Med. 2002;195:151-160.
    • (2002) J Exp Med , vol.195 , pp. 151-160
    • Takaki, S.1    Morita, H.2    Tezuka, Y.3    Takatsu, K.4
  • 18
    • 19944400789 scopus 로고    scopus 로고
    • Quantifi-cation of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice
    • Ema H, Sudo K, Seita J, Maeda A, et al. Quantifi-cation of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice. Dev Cell. 2005;8:907-914.
    • (2005) Dev Cell , vol.8 , pp. 907-914
    • Ema, H.1    Sudo, K.2    Seita, J.3    Maeda, A.4
  • 19
    • 0030613545 scopus 로고    scopus 로고
    • Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling
    • Rui L, Mathews LS, Hotta K, Gustafson TA, Carter-Su C. Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling. Mol Cell Biol. 1997;17:6633-6644.
    • (1997) Mol Cell Biol , vol.17 , pp. 6633-6644
    • Rui, L.1    Mathews, L.S.2    Hotta, K.3    Gustafson, T.A.4    Carter-Su, C.5
  • 20
    • 0030812414 scopus 로고    scopus 로고
    • Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation
    • Yokouchi M, Suzuki R, Masuhara M, Komiya S, Inoue A, Yoshimura A. Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation. Oncogene. 1997;15:7-15.
    • (1997) Oncogene , vol.15 , pp. 7-15
    • Yokouchi, M.1    Suzuki, R.2    Masuhara, M.3    Komiya, S.4    Inoue, A.5    Yoshimura, A.6
  • 21
    • 0032418850 scopus 로고    scopus 로고
    • Identification and characterization of novel substrates of Trk receptors in developing neurons
    • Qian X, Riccio A, Zhang Y, Ginty DD. Identification and characterization of novel substrates of Trk receptors in developing neurons. Neuron. 1998;21:1017-1029.
    • (1998) Neuron , vol.21 , pp. 1017-1029
    • Qian, X.1    Riccio, A.2    Zhang, Y.3    Ginty, D.D.4
  • 22
    • 0034720476 scopus 로고    scopus 로고
    • Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins
    • Iseki M, Takaki S, Takatsu K. Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins. Biochem Biophys Res Commun. 2000;272:45-54.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 45-54
    • Iseki, M.1    Takaki, S.2    Takatsu, K.3
  • 23
    • 0034610745 scopus 로고    scopus 로고
    • PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis
    • Riedel H, Yousaf N, Zhao Y, Dai H, Deng Y, Wang J. PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis. Oncogene. 2000;19:39-50.
    • (2000) Oncogene , vol.19 , pp. 39-50
    • Riedel, H.1    Yousaf, N.2    Zhao, Y.3    Dai, H.4    Deng, Y.5    Wang, J.6
  • 24
    • 0033637359 scopus 로고    scopus 로고
    • Control of B cell production by the adaptor protein lnk. Definition of a conserved family of signal-modulating proteins
    • Takaki S, Sauer K, Iritani BM, et al. Control of B cell production by the adaptor protein lnk. Definition of a conserved family of signal-modulating proteins. Immunity. 2000;13:599-609.
    • (2000) Immunity , vol.13 , pp. 599-609
    • Takaki, S.1    Sauer, K.2    Iritani, B.M.3
  • 25
    • 0035811366 scopus 로고    scopus 로고
    • Lnk adaptor: Novel negative regulator of B cell lymphopoiesis
    • Rudd CE. Lnk adaptor: novel negative regulator of B cell lymphopoiesis. Sci STKE. 2001;85:PE1.
    • (2001) Sci STKE , vol.85
    • Rudd, C.E.1
  • 26
    • 0037124306 scopus 로고    scopus 로고
    • Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice
    • Velazquez L, Cheng AM, Fleming HE, et al. Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. J Exp Med. 2002;195:1599-1611.
    • (2002) J Exp Med , vol.195 , pp. 1599-1611
    • Velazquez, L.1    Cheng, A.M.2    Fleming, H.E.3
  • 27
    • 4544277651 scopus 로고    scopus 로고
    • Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis
    • Tong W, Lodish HF. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med. 2004;200:569-580.
    • (2004) J Exp Med , vol.200 , pp. 569-580
    • Tong, W.1    Lodish, H.F.2
  • 28
    • 0034046944 scopus 로고    scopus 로고
    • Plat-E: An efficient and stable system for transient packaging of retroviruses
    • Morita S, Kojima T, Kitamura T. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 2000;7:1063-1066.
    • (2000) Gene Ther , vol.7 , pp. 1063-1066
    • Morita, S.1    Kojima, T.2    Kitamura, T.3
  • 30
    • 0035131695 scopus 로고    scopus 로고
    • SH2-B and APS are multimeric adapters that augment TrkA signaling
    • Qian X, Ginty DD. SH2-B and APS are multimeric adapters that augment TrkA signaling. Mol Cell Biol. 2001;21:1613-1620.
    • (2001) Mol Cell Biol , vol.21 , pp. 1613-1620
    • Qian, X.1    Ginty, D.D.2
  • 31
    • 0032147025 scopus 로고    scopus 로고
    • Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells
    • Vermeulen M, Le Pesteur F, Gagnerault MC, Mary JY, Sainteny F, Lepault F. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood. 1998;92:894-900.
    • (1998) Blood , vol.92 , pp. 894-900
    • Vermeulen, M.1    Le Pesteur, F.2    Gagnerault, M.C.3    Mary, J.Y.4    Sainteny, F.5    Lepault, F.6
  • 32
    • 0035889143 scopus 로고    scopus 로고
    • Molecular pathways in bone marrow homing: Dominant role of alpha(4)beta(1) over beta(2)-integrins and selectins
    • Papayannopoulou T, Priestley GV, Nakamoto B, Zafiropoulos V, Scott LM. Molecular pathways in bone marrow homing: dominant role of alpha(4)beta(1) over beta(2)-integrins and selectins. Blood. 2001;98:2403-2411.
    • (2001) Blood , vol.98 , pp. 2403-2411
    • Papayannopoulou, T.1    Priestley, G.V.2    Nakamoto, B.3    Zafiropoulos, V.4    Scott, L.M.5
  • 33
    • 0345491600 scopus 로고    scopus 로고
    • Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing
    • Scott LM, Priestley GV, Papayannopoulou T. Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing. Mol Cell Biol. 2003;23:9349-9360.
    • (2003) Mol Cell Biol , vol.23 , pp. 9349-9360
    • Scott, L.M.1    Priestley, G.V.2    Papayannopoulou, T.3
  • 34
    • 0242552572 scopus 로고    scopus 로고
    • Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein
    • Nobuhisa I, Takizawa M, Takaki S, et al. Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein. Mol Cell Biol. 2003;23:8486-8494.
    • (2003) Mol Cell Biol , vol.23 , pp. 8486-8494
    • Nobuhisa, I.1    Takizawa, M.2    Takaki, S.3
  • 36
    • 0037155344 scopus 로고    scopus 로고
    • SH2-Bb is a Rac-binding protein that regulates cell motility
    • Diakonova M, Gunter DR, Herrington J, Carter-Su C. SH2-Bb is a Rac-binding protein that regulates cell motility. J Biol Chem. 2002;277:10669-10677.
    • (2002) J Biol Chem , vol.277 , pp. 10669-10677
    • Diakonova, M.1    Gunter, D.R.2    Herrington, J.3    Carter-Su, C.4
  • 37
    • 0842267299 scopus 로고    scopus 로고
    • Roles of a conserved family of adaptor proteins, Lnk, SH2-B, and APS, for mast cell development, growth, and functions: APS-deficiency causes augmented degranulation and reduced actin assembly
    • Kubo-Akashi C, Iseki M, Kwon SM, Takizawa H, Takatsu K, Takaki S. Roles of a conserved family of adaptor proteins, Lnk, SH2-B, and APS, for mast cell development, growth, and functions: APS-deficiency causes augmented degranulation and reduced actin assembly. Biochem Biophys Res Commun. 2004;315:356-362.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 356-362
    • Kubo-Akashi, C.1    Iseki, M.2    Kwon, S.M.3    Takizawa, H.4    Takatsu, K.5    Takaki, S.6
  • 38
    • 0842307897 scopus 로고    scopus 로고
    • Increased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domains
    • Iseki M, Kubo C, Kwon SM, et al. Increased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domains. Mol Cell Biol. 2004;24:2243-2250.
    • (2004) Mol Cell Biol , vol.24 , pp. 2243-2250
    • Iseki, M.1    Kubo, C.2    Kwon, S.M.3
  • 39
    • 0037206949 scopus 로고    scopus 로고
    • Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity
    • Yabana N, Shibuya M. Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity. Oncogene. 2002;21:7720-7729.
    • (2002) Oncogene , vol.21 , pp. 7720-7729
    • Yabana, N.1    Shibuya, M.2
  • 40
    • 0035473464 scopus 로고    scopus 로고
    • Vav proteins, adaptors and cell signaling
    • Bustelo XR. Vav proteins, adaptors and cell signaling. Oncogene. 2001;20:6372-6381.
    • (2001) Oncogene , vol.20 , pp. 6372-6381
    • Bustelo, X.R.1
  • 41
    • 0142084736 scopus 로고    scopus 로고
    • Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
    • Gu Y, Filippi MD, Cancelas JA, et al. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science. 2003;302:445-449.
    • (2003) Science , vol.302 , pp. 445-449
    • Gu, Y.1    Filippi, M.D.2    Cancelas, J.A.3
  • 42
    • 0034521857 scopus 로고    scopus 로고
    • Identification of actin binding protein, ABP-280, as a binding partner of human Lnk adaptor protein
    • He X, Li Y, Schembri-King J, Jakes S, Hayashi J. Identification of actin binding protein, ABP-280, as a binding partner of human Lnk adaptor protein. Mol Immunol. 2000;37:603-612.
    • (2000) Mol Immunol , vol.37 , pp. 603-612
    • He, X.1    Li, Y.2    Schembri-King, J.3    Jakes, S.4    Hayashi, J.5
  • 43
    • 0035202874 scopus 로고    scopus 로고
    • Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration
    • Calderwood DA, Huttenlocher A, Kiosses WB, et al. Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration. Nat Cell Biol. 2001;3:1060-1068.
    • (2001) Nat Cell Biol , vol.3 , pp. 1060-1068
    • Calderwood, D.A.1    Huttenlocher, A.2    Kiosses, W.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.