CD44 and CD69 represent different types of cell-surface activation markers for human eosinophils

American Journal of Respiratory Cell and Molecular Biology

Volumn 18, Issue 6, 1998, Pages 860-866

  Matsumoto, Kenji ^a   Appiah Pippim, James ^a   Schleimer, Robert P ^a   Bickel, Carol A ^a   Beck, Lisa A ^a   Bochner, Bruce S ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; CYTOKINE; HERMES ANTIGEN; HYALURONIC ACID; INTERLEUKIN 5; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; T LYMPHOCYTE ANTIGEN;

ARTICLE; CELL CULTURE; CELL LINE; DOSE RESPONSE; DRUG EFFECT; EOSINOPHIL; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; LUNG LAVAGE; METABOLISM; PATHOLOGY;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD44; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; FLOW CYTOMETRY; HUMANS; HYALURONIC ACID; INTERLEUKIN-5; MEMBRANE PROTEINS;

EID: 0032090255     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.18.6.3159     Document Type: Article

References (45)

1. Sur, S., C. R. Adolphson, and G. J. Gleich. 1993. Eosinophils: biochemical and cellular aspects. In Allergy Principles and Practice, 4th ed. E. Middleton, C. E. Reed, E. F. Ellis, J. N. F. Adkinson, J. W. Yunginger, and W. Busse, editors. CV Mosby, St. Louis. 169-200.
2. Weller, P. F. 1991. The immunobiology of eosinophils. N. Engl. J. Med. 324: 1110-1118.
3. Silberstein, D. S., K. F. Austen, and W. F. Owen, Jr. 1989. Hemopoietins for eosinophils. Hematol. Oncol. Clin. North Am. 3:511-533.
4. Peters, M. D., G. J. Gleich, S. L. Dunette, and T. Fukuda. 1988. Ultrastructural study of eosinophils from patients with the hypereosinophilic syndrome: a morphological basis of hypodense cells. Blood 71:780-785.
5. Caulfield, J. P., A. Hein, M. E. Rothenberg, W. F. Owen, R. J. Soberman, R. L. Stevens, and K. F. Austen. 1990. A morphometric study of normodense and hypodense human eosinophils that are derived in vivo and in vitro. Am. J. Pathol. 137:27-41.
6. Frick, W. E., J. B. Sedgwick, and W. W. Busse. 1988. Hypodense eosinophils in allergic rhinitis. J. Allergy Clin. Immunol. 82:119-127.
7. Fukuda, T., S. L. Dunnette, C. E. Reed, S. J. Ackerman, M. S. Peters, and G. J. Gleich. 1985. Increased numbers of hypodense eosinophils in the blood of patients with bronchial asthma. Am. Rev. Respir. Dis. 132:981-985.
8. Hartnell, A., R. Moqbel, G. M. Walsh, B. Bradley, and A. B. Kay. 1990. Fcγ and CD11/CD18 receptor expression on normal density and low-density human eosinophils. Immunology 69:264-270.
9. Hansel, T. T., J. B. Braunstein, C. Walker, K. Blaser, P. L. B. Bruijnzeel, J. C. Virchow, and C. Virchow. 1991. Sputum eosinophils from asthmatics express ICAM-1 and HLA-DR. Clin. Exp. Immunol. 86:271-277.
10. Hansel, T. T., I. J. M. Devries, J. M. Carballido, R. K. Braun, N. Carballidoperrig, S. Rihs, K. Blaser, and C. Walker. 1992. Induction and function of eosinophil intercellular adhesion molecule-1 and HLA-DR. J. Immunol. 149:2130-2136.
11. Hartnell, A., A. B. Kay, and A. J. Wardlaw. 1992. IFN-gamma induces expression of FcγRIII (CD16) on human eosinophils. J. Immunol. 148:1471-1478.
12. Mawhorter, S. D., D. A. Stephany, E. A. Ottesen, and T. B. Nutman. 1996. Identification of surface molecules associated with physiologic activation of eosinophils-application of whole-blood flow cytometry to eosinophils. J. Immunol. 156:4851-4858.
13. Hartnell, A., D. S. Robinson, A. B. Kay, and A. J. Wardlaw. 1993. CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines. Immunology 80:281-286.
14. Hamann, J., H. Fiebig, and M. Strauss. 1993. Expression cloning of the early activation antigen CD69, a type-II integral membrane protein with a C-type lectin domain. J. Immunol. 150:4920-4927.
15. Santis, A. G., M. Lopez-Cabrera, F. Sanchez-Madrid, and N. Proudfoot. 1995. Expression of the early lymphocyte activation antigen CD69, a C-type lectin, is regulated by mRNA degradation associated with AU-rich sequence motifs. Eur. J. Immunol. 25:2142-2146.
16. Shaw, S., G. G. Luce, W. R. Gilks, K. Anderson, K. Ault, B. S. Bochner, L. Boumsell, S. M. Denning, E. G. Engleman, T. Fleisher, A. S. Freedman, D. A. Fox, J. Gailit, J. Carlos Gutierrez-Ramos, P. E. Hurtubise, P. Lansdorp, M. T. Lotze, S. Mawhorter, G. Marti, Y. Matsuo, J. Minowada, A. Michelson, L. Picker, J. Ritz, E. Roos, C. E. Van der Schoot, T. A. Springer, T. F. Tedder, M. J. Telen, J. S. Thompson, and P. Valent. 1995. Leukocyte differentiation antigen database. In Leukocyte Typing V: White Cell Differentiation Antigens. S. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder, and R. Todd, editors. Oxford University Press, New York. 16-198.
17. Ebisawa, M., R. P. Schleimer, C. Bickel, and B. S. Bochner. 1995. Phenotyping of purified human peripheral blood eosinophils using the blind panel mAb. In Leukocyte Typing V: White Cell Differentiation Antigens, S. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder, and R. Todd, editors. Oxford University Press, New York. 1036-1038.
18. Hansel, T. T., J. D. Pound, D. Pilling, G. D. Kitas, M. Salmon, T. A. Gentle, S. S. Lee, and R. A. Thompson. 1989. Purification of human eosinophils by negative selection using immunomagnetic heads. J. Immunol. Methods 122:97-103.
19. Kroegel, C., M. C. Liu, W. M. Hubbard, L. M. Lichtenstein, and B. S. Bochner. 1994. Blood and bronchoalveolar eosinophils in allergic subjects following segmental antigen challenge: surface phenotype, density heterogeneity, and prostanoid production. J. Allergy Clin. Immunol. 93:725-734.
20. Matsumoto, K., R. P. Schleimer, H. Saito, Y. Iikura, and B. S. Bochner. 1995. Induction of apoptosis in human eosinophils by anti-fas antibody treatment in vitro. Blood 86:1437-1443.
21. Blom, T., R. Y. Huang, M. Aveskogh, K. Nilsson, and L. Hellman. 1992. Phenotypic characterization of KU812, a cell line identified as an immature human basophilic leukocyte. Eur. J. Immunol. 22:2025-2032.
22. Georas, S. N., M. C. Liu, W. Newman, W. D. Beall, B. A. Stealey, and B. S. Bochner. 1992. Altered adhesion molecule expression and endothelial activation accompany the recruitment of human granulocytes to the lung following segmental antigen challenge. Am. J. Respir. Cell Mol. Biol. 7:261-269.
23. Bochner, B. S., S. A. Sterbinsky, C. A. Bickel, S. Werfel, M. Wein, and W. Newman. 1994. Differences between human eosinophils and neutrophils in the function and expression of sialic acid-containing counterligands for E-selectin. J. Immunol. 152:774-782.
24. Miyake, K., C. B. Underbill, J. Lesley, and P. W. Kincade. 1990. Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. J. Exp. Med. 172:69-75.
25. Matsumoto, K., S. A. Sterbinsky, C. A. Bickel, D. W. Zhou, N. L. Kovach, and B. S. Bochner. 1997. Regulation of α4 integrin-mediated adhesion of human eosinophils to fibronectin and vascular cell adhesion molecule-1 (VCAM-1). J. Allergy Clin. Immunol. 99:648-656.
26. Nishikawa, K., T. Morii, H. Ako, K. Hamada, S. Saito, and N. Narita. 1992. In vivo expression of CD69 on lung eosinophils in eosinophilic pneumonia - CD69 as a possible activation marker for eosinophils. J. Allergy Clin. Immunol. 90:169-174.
27. Wallen, N., H. Kita, D. Weiler, and G. J. Gleich. 1991. Glucocorticoids inhibit cytokine-mediated eosinophil survival. J. Immunol. 147:3490-3495.
28. Kita, H., S. Horie, and G. J. Gleich. 1996. Extracellular matrix proteins attenuate activation and degranulation of stimulated eosinophils. J. Immunol. 156:1174-1181.
29. Walsh, G. M.,M. L. Williamson, F. A. Symon, G. B. Willars, and A. J. Wardlaw. 1996. Ligation of CD69 induces apoptosis and cell death in human eosinophils cultured with granulocyte-macrophage colony-stimulating factor. Blood 87:2815-2821.
30. Santis, A. G., M. R. Campanero, J. L. Alonso, A. Tugores, M. A. Alonso, E. Yague, J. P. Pivel, and F. Sanchez-Madrid. 1992. Tumor necrosis factor-alpha production induced in T-lymphocytes through the AIM/CD69 activation pathway. Eur. J. Immunol. 22:1253-1259.
31. Rand, T. H., W. W. Cruikshank, D. M. Center, and P. F. Weller. 1991. CD4-mediated stimulation of human eosinophils - lymphocyte chemoattractant factor and other CD4-binding ligands elicit eosinophil migration. J. Exp. Med. 173:1521-1528.
32. Hansel, T. T., and C. Walker. 1992. The migration of eosinophils into the sputum of asthmatics: the role of adhesion molecules. Clin. Exp. Allergy 22:345-356.
33. Gauchat, J. F., S. Henchoz, D. Fattah, G. Mazzei, J. P. Aubry, T. Jomotte, L. Dash, K. Page, R. Solari, D. Aldebert, M. Capron, C. Dahinden, and J. Y. Bonnefoy. 1995. CD40 ligand is functionally expressed on human eosinophils. Eur. J. Immunol. 25:863-865.
34. Lesley, J. R., R. Hyman, and P. W. Kincade. 1993. CD44 and its interaction with extracellular matrix. Adv. Immunol. 54:271-298.
35. Degrendele, H. C., P. Estess, L. J. Picker, and M. H. Siegelman. 1996. CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway. J. Exp. Med. 183: 1119-1130.
36. Levesque, M. C., and B. F. Haynes. 1996. In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expression. J. Immunol. 156:1557-1565.
37. Haynes, B. F., L. P. Hale, K. L. Patton, M. E. Martin, and R. M. McCallum. 1991. Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Upregulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis. Arthritis Rheum. 34:1434-1440.
38. Campanero, M. R., R. Pulido, J. L. Alonso, J. P. Pivel, F. X. Pimentel-Muinos, M. Fresno, and F. Sanchez-Madrid. 1991. Down-regulation by tumor necrosis factor-alpha of neutrophil cell surface expression of the sialophorin CD43 and the hyaluronate receptor CD44 through a proteolytic mechanism. Eur. J. Immunol. 21:3045-3048.
39. Bazil, V., and J. L. Strominger. 1994. Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes - induction of cleavage of L-selectin via CD16. J. Immunol. 152:1314-1322.
40. Murakami, S., K. Miyake, C. H. June, P. W. Kincade, and R. J. Hodes. 1990. IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and 1g secretory activity and binds to hyaluronate. J. Immunol. 145:3618-3623.
41. Neeley, S. P., K. J. Hamann, S. R. White, S. L. Baranowski, R. A. Burch, and A. R. Leff. 1993. Selective regulation of expression of surface adhesion molecules Mac-1, L-selection, and VLA-4 on human eosinophils and neutrophils. Am. J. Respir. Cell Mol. Biol. 8:633-639.
42. Hamann, K. J., T. L. Dowling, S. P. Neeley, J. A. Grant, and A. R. Leff. 1995. Hyaluronic acid enhances cell proliferation during eosinopoiesis through the CD44 surface antigen. J. Immunol. 154:4073-4080.
43. Lazaar, A. L., S. M. Albelda, J. M. Pilewski, B. Brennan, E. Pure, and R. A. Panettieri. 1994. T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J. Exp. Med. 180:807-816.
44. Katoh, S. Z. Zheng, K. Oritani, T. Shimozato, and P. W. Kincade. 1995. Glycosylation of CD44 negatively regulates its recognition of hyaluronan. J. Exp. Med. 182:419-429.
45. Bartolazzi, A., A. Nocks, A. Aruffo, F. Spring, and I. Stamenkovic. 1996. Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan. J. Cell Biol. 132:1199-1208.