메뉴 건너뛰기




Volumn 187, Issue 2, 2011, Pages 127-134

Omega-3 fatty acid supplementation in cancer therapy: Does eicosapentanoic acid influence the radiosensitivity of tumor cells?

Author keywords

Eicosapentanoic acid; EPA; Lipid peroxidation; Membrane; N 3 PUFA

Indexed keywords

5,8,11,14,17 ICOSAPENTAENOIC ACID; ALCOHOL; BOVINE SERUM ALBUMIN; OMEGA 3 FATTY ACID; ICOSAPENTAENOIC ACID; RADIOSENSITIZING AGENT;

EID: 79954433624     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-010-2166-6     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 38949108301 scopus 로고    scopus 로고
    • PPARγ1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells
    • Allred CD, Talbert DR, Southard RC, et al. PPAR gamma1 as a molecular target of eicosapentaenoic add in human colon cancer (HT-29) cells. J Nutr 2008;138:250-6. (Pubitemid 351213635)
    • (2008) Journal of Nutrition , vol.138 , Issue.2 , pp. 250-256
    • Allred, C.D.1    Talbert, D.R.2    Southard, R.C.3    Wang, X.4    Kilgore, M.W.5
  • 2
    • 27144513240 scopus 로고    scopus 로고
    • Cancer-assodated malnutrition
    • Argiles JM. Cancer-assodated malnutrition. Eur J Oncol Nurs 2005;9(Suppl 2):S39-50.
    • (2005) Eur J Oncol Nurs , vol.9 , Issue.SUPPL. 2
    • Argiles, J.M.1
  • 3
    • 58149160021 scopus 로고    scopus 로고
    • Omega-3 fatty adds suppress growth of SW620 human colon cancer xenografts in nude mice
    • Bathen TF, Holmgren K, Lundemo AG, et al. Omega-3 fatty adds suppress growth of SW620 human colon cancer xenografts in nude mice. Anticancer Res 2008;28:3717-23.
    • (2008) Anticancer Res , vol.28 , pp. 3717-3723
    • Bathen, T.F.1    Holmgren, K.2    Lundemo, A.G.3
  • 4
    • 77449155377 scopus 로고    scopus 로고
    • Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses
    • Barzan D, Maier P, Zeller WJ, et al. Overexpression of caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses. Strahlenther Onkol 2010;186:99-106.
    • (2010) Strahlenther Onkol , vol.186 , pp. 99-106
    • Barzan, D.1    Maier, P.2    Zeller, W.J.3
  • 5
    • 73449119961 scopus 로고    scopus 로고
    • Radiation- and chemoinduced multidrug resistance in colon carcinoma cells
    • Bartkowiak D, Stempfhuber M, Wiegel T, et al. Radiation- and chemoinduced multidrug resistance in colon carcinoma cells. Strahlenther Onkol 2009;185:815-20.
    • (2009) Strahlenther Onkol , vol.185 , pp. 815-820
    • Bartkowiak, D.1    Stempfhuber, M.2    Wiegel, T.3
  • 6
    • 4644316939 scopus 로고    scopus 로고
    • Molecular targeting in radiotherapy of lung cancer
    • DOI 10.1016/j.lungcan.2004.07.975, PII S0169500204800254, Trends in Diagnostic and Therapy of Lung Cancer
    • Baumann M, Krause M, Zips D, et al. Molecular targeting in radiotherapy of lung cancer. Lung Cancer 2004;45(Suppl 2):S187-97. (Pubitemid 39488188)
    • (2004) Lung Cancer , vol.45 , Issue.SUPPL. 2
    • Baumann, M.1    Krause, M.2    Zips, D.3    Petersen, C.4    Dittmann, K.5    Dorr, W.6    Rodemann, H.-P.7
  • 7
    • 0026342403 scopus 로고
    • Anticachectic and antitumor effect of eicosapentaenoic acid and its effect on protein turnover
    • Beck SA, Smith KL, Tisdale MJ. Anticachectic and antitumor effect of eicosapentaenoic acid and its effect on protein turnover. Cancer Res 1991;51:6089-93.
    • (1991) Cancer Res , vol.51 , pp. 6089-6093
    • Beck, S.A.1    Smith, K.L.2    Tisdale, M.J.3
  • 8
    • 33746763511 scopus 로고    scopus 로고
    • The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer
    • DOI 10.1016/j.cdp.2006.04.008, PII S0361090X06000870
    • Black HS, Rhodes LE. The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. Cancer Detect Prev 2006;30:224-32. (Pubitemid 44163058)
    • (2006) Cancer Detection and Prevention , vol.30 , Issue.3 , pp. 224-232
    • Black, H.S.1    Rhodes, L.E.2
  • 13
    • 0030808735 scopus 로고    scopus 로고
    • Low-dose eicosapentaenoic or docosahexaenoic acid administration modifies fatty acid composition and does not affect susceptibility to oxidative stress in rat erythrocytes and tissues
    • DOI 10.1007/s11745-997-0139-4
    • Calviello G, Palozza P, Franceschelli P, et al. Low-dose eicosapentaenoic or docosahexaenoic acid administration modifies fatty acid composition and does not affect susceptibility to oxidative stress in rat erythrocytes and tissues. Lipids 1997;32:1075-83. (Pubitemid 27459416)
    • (1997) Lipids , vol.32 , Issue.10 , pp. 1075-1083
    • Calviello, G.1    Palozza, P.2    Franceschelli, P.3    Bartoli, G.M.4
  • 14
    • 53349168404 scopus 로고    scopus 로고
    • Eicosapentaenoic-acid-derived isoprostanes: Synthesis and discovery of two major isoprostanes
    • Chang CT, Patel P, Kang N, et al. Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes. Bioorg Med Chem 2008;18:5523-7.
    • (2008) Bioorg Med Chem , vol.18 , pp. 5523-5527
    • Chang, C.T.1    Patel, P.2    Kang, N.3
  • 15
    • 56349109532 scopus 로고    scopus 로고
    • Bioactive dietary long-chain fatty adds: Emerging mechanisms of action
    • Chapkin RS, McMurray DN, Davidson LA, et al. Bioactive dietary long-chain fatty adds: emerging mechanisms of action. Br J Nutr 2008;100:1152-7.
    • (2008) Br J Nutr , vol.100 , pp. 1152-1157
    • Chapkin, R.S.1    McMurray, D.N.2    Davidson, L.A.3
  • 16
    • 0027427508 scopus 로고
    • Mechanisms and effects of lipid peroxidation
    • Cheeseman KH. Mechanisms and effects of lipid peroxidation. Mol Aspects Med 1993;14:191-7.
    • (1993) Mol Aspects Med , vol.14 , pp. 191-197
    • Cheeseman, K.H.1
  • 17
    • 0032886232 scopus 로고    scopus 로고
    • Induction of apoptosis in HL-60 cells by eicosapentaenoic acid (EPA) is associated with downregulation of bcl-2 expression
    • DOI 10.1016/S0304-3835(99)00224-4, PII S0304383599002244
    • Chiu LC, Wan JM. Induction of apoptosis in HL-60 cells by eicosapentae- noic add (EPA) is assodated with downregulation of bcl-2 expression. Cancer Lett 1999;145:17-27. (Pubitemid 29459065)
    • (1999) Cancer Letters , vol.145 , Issue.1-2 , pp. 17-27
    • Chiu, L.C.M.1    Wan, J.M.F.2
  • 18
    • 0033392868 scopus 로고    scopus 로고
    • Effect of eicosapentaenoic acid on the proliferation and incidence of apoptosis in the colorectal cell line HT29
    • Clarke RG, Lund EK, Latham P, et al. Effect of eicosapentaenoic add on the proliferation and inddence of apoptosis in the colorectal cell line HT29. Lipids 1999;34:1287-95. (Pubitemid 30044267)
    • (1999) Lipids , vol.34 , Issue.12 , pp. 1287-1295
    • Clarke, R.G.1    Lund, E.K.2    Latham, P.3    Pinder, A.C.4    Johnson, I.T.5
  • 20
    • 62049084741 scopus 로고    scopus 로고
    • Mechanisms of action of eicosapentaenoic add in bladder cancer cells in vitro: Alterations in mitochondrial metabolism, reactive oxygen spedes generation and apoptosis induction
    • Colquhoun A. Mechanisms of action of eicosapentaenoic add in bladder cancer cells in vitro: alterations in mitochondrial metabolism, reactive oxygen spedes generation and apoptosis induction. J Urol 2009;181:1885-93.
    • (2009) J Urol , vol.181 , pp. 1885-1893
    • Colquhoun, A.1
  • 21
    • 0035980762 scopus 로고    scopus 로고
    • γ-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells
    • DOI 10.1016/S1388-1981(01)00136-6, PII S1388198101001366
    • Colquhoun A, Schumacher RI. gamma-linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. Biochim Biophys Acta Mol Cell Biol Lipids 2001;1533:207-19. (Pubitemid 33127272)
    • (2001) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1533 , Issue.3 , pp. 207-219
    • Colquhoun, A.1    Schumacher, R.I.2
  • 22
    • 34447114450 scopus 로고    scopus 로고
    • γ-linolenic acid therapy of human glioma - A review of in vitro, in vivo, and clinical studies
    • Das UN. gamma-linolenic acid therapy of human gliomas - a review of in vitro, in vivo, and clinical studies. Med Sci Monitor 2007;13:RA119-31. (Pubitemid 47037681)
    • (2007) Medical Science Monitor , vol.13 , Issue.7
    • Das, U.N.1
  • 23
    • 75649095683 scopus 로고    scopus 로고
    • Nuclear EGFR as novel therapeutic target: Insights into nuclear translocation and function
    • Dittmann K, Mayer C, Rodemann HP. Nuclear EGFR as novel therapeutic target: insights into nuclear translocation and function. Strahlenther Onkol 2010;186:1-6.
    • (2010) Strahlenther Onkol , vol.186 , pp. 1-6
    • Dittmann, K.1    Mayer, C.2    Rodemann, H.P.3
  • 24
    • 0021299068 scopus 로고
    • The effects of ionizing radiation on biomembrane structure and function
    • Edwards JC, Chapman D, Cramp WA, et al. The effects of ionizing radiation on biomembrane structure and function. Prog Biophys Mol Biol 1984;43:71-93.
    • (1984) Prog Biophys Mol Biol , vol.43 , pp. 71-93
    • Edwards, J.C.1    Chapman, D.2    Cramp, W.A.3
  • 26
    • 38149075979 scopus 로고    scopus 로고
    • Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo
    • Gabrys D, Dörfler A, Yaromina A, et al. Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo. Strahlenther Onkol 2008;184:48-53.
    • (2008) Strahlenther Onkol , vol.184 , pp. 48-53
    • Gabrys, D.1    Dörfler, A.2    Yaromina, A.3
  • 27
    • 0025766898 scopus 로고
    • Oxy-radical metabolism and control of tumor-growth
    • Galeotti T, Masotti L, Borrello S, et al. Oxy-radical metabolism and control of tumor-growth. Xenobiotica 1991;21:1041-51.
    • (1991) Xenobiotica , vol.21 , pp. 1041-1051
    • Galeotti, T.1    Masotti, L.2    Borrello, S.3
  • 29
    • 0034899819 scopus 로고    scopus 로고
    • Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants
    • Heimli H, Finstad HS, Drevon CA. Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants. Lipids 2001;36:613-21. (Pubitemid 32703300)
    • (2001) Lipids , vol.36 , Issue.6 , pp. 613-621
    • Heimli, H.1    Finstad, H.S.2    Drevon, C.A.3
  • 30
    • 0034643267 scopus 로고    scopus 로고
    • Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells?
    • DOI 10.1006/bbrc.2000.2484
    • Igarashi M, Miyazawa T. Do conjugated eicosapentaenoic acid and conjugated docosahexaenoic acid induce apoptosis via lipid peroxidation in cultured human tumor cells? Biochem Biophys Res Commun 2000;270:649-56. (Pubitemid 30446889)
    • (2000) Biochemical and Biophysical Research Communications , vol.270 , Issue.2 , pp. 649-656
    • Igarashi, M.1    Miyazawa, T.2
  • 31
    • 0035348128 scopus 로고    scopus 로고
    • Radiation responses in plasma membrane Review of the present state and future trends
    • Köteles GJ, Somosy Z. Radiation responses in plasma membrane. Review of the present state and future trends. Cell Mol Biol 2001;47:473-84.
    • (2001) Cell Mol Biol , vol.47 , pp. 473-484
    • Köteles, G.J.1    Somosy, Z.2
  • 32
    • 15944428554 scopus 로고    scopus 로고
    • Involvement of hydroperoxide in mitochondria in the induction of apoptosis by the eicosapentaenoic acid
    • DOI 10.1080/10715760500043587
    • Koumura T, Nakamura C, Nakagawa Y. Involvement of hydroperoxide in mitochondria in the induction of apoptosis by the eicosapentaenoic acid. Free Radic Res 2005;39:225-35. (Pubitemid 40439385)
    • (2005) Free Radical Research , vol.39 , Issue.3 , pp. 225-235
    • Koumura, T.1    Nakamura, C.2    Nakagawa, Y.3
  • 33
    • 0029822029 scopus 로고    scopus 로고
    • Cell cycle arrest and induction of apoptosis in pancreatic cancer cells exposed to eicosapentaenoic acid in vivo
    • Lai PBS, Ross JA, Fearon KCH, et al. Cell cycle arrest and induction of apoptosis in pancreatic cancer cells exposed to eicosapentaenoic acid in vitro. Br J Cancer 1996;74:1375-83. (Pubitemid 26370727)
    • (1996) British Journal of Cancer , vol.74 , Issue.9 , pp. 1375-1383
    • Lai, P.B.S.1    Ross, J.A.2    Fearon, K.C.H.3    Anderson, J.D.4    Carter, D.C.5
  • 34
    • 0022573979 scopus 로고
    • Membrane effects of ionizing radiation and hyperthermia
    • Leyko W, Bartosz G. Membrane effects of ionizing radiation and hyperthermia. Int J Radiat Biol Relat Stud Phys Chem Med 1986;49:743-70. (Pubitemid 16119504)
    • (1986) International Journal of Radiation Biology , vol.49 , Issue.5 , pp. 743-770
    • Leyko, W.1    Bartosz, G.2
  • 35
    • 38149063793 scopus 로고    scopus 로고
    • Recombinant human erythropoietin alpha improves the efficacy of radiotherapy of a human tumor xenograft, affecting tumor cells and microvessels
    • Lövey J, Bereczky B, Gilly R, et al. Recombinant human erythropoietin alpha improves the efficacy of radiotherapy of a human tumor xenograft, affecting tumor cells and microvessels. Strahlenther Onkol 2008;184:1-7.
    • (2008) Strahlenther Onkol , vol.184 , pp. 1-7
    • Lövey, J.1    Bereczky, B.2    Gilly, R.3
  • 36
    • 60649121936 scopus 로고    scopus 로고
    • The rationale and design of the FORomegaARD Trial: A randomized, double-blind, placebo-controlled, independent study to test the efficacy of n-3 PUFA for the maintenance of normal sinus rhythm in patients with previous atrial fibrillation
    • Macchia A, Varini S, Grancelli H, et al. The rationale and design of the FORomegaARD Trial: a randomized, double-blind, placebo-controlled, independent study to test the efficacy of n-3 PUFA for the maintenance of normal sinus rhythm in patients with previous atrial fibrillation. Am Heart J 2009;157:423-7.
    • (2009) Am Heart J , vol.157 , pp. 423-427
    • MacChia, A.1    Varini, S.2    Grancelli, H.3
  • 38
    • 0036267445 scopus 로고    scopus 로고
    • Radiation-induced changes in permeability in unilamellar phospholipid liposomes
    • Marathe D, Mishra KP. Radiation-induced changes in permeability in unilamellar phospholipid liposomes. Radiat Res 2002;157:685-92. (Pubitemid 34569137)
    • (2002) Radiation Research , vol.157 , Issue.6 , pp. 685-692
    • Marathe, D.1    Mishra, K.P.2
  • 40
    • 67149086939 scopus 로고    scopus 로고
    • Molecular targeted treatment and radiation therapy for rectal cancer
    • Marquardt F, Rödel F, Capalbo G, et al. Molecular targeted treatment and radiation therapy for rectal cancer. Strahlenther Onkol 2009;185:371-8.
    • (2009) Strahlenther Onkol , vol.185 , pp. 371-378
    • Marquardt, F.1    Rödel, F.2    Capalbo, G.3
  • 41
    • 47049114843 scopus 로고    scopus 로고
    • Human biochemistry of the isoprostane pathway
    • Milne GL, Yin H, Morrow JD. Human biochemistry of the isoprostane pathway. J Biol Chem 2008;283:15533-7.
    • (2008) J Biol Chem , vol.283 , pp. 15533-15537
    • Milne, G.L.1    Yin, H.2    Morrow, J.D.3
  • 42
    • 48249088499 scopus 로고    scopus 로고
    • The combined effect of fludarabine monophosphate and radiation as well as gemcitabine and radiation on squamous carcinoma tumor cell lines in vitro
    • Nitsche M, Christiansen H, Hermann RM, et al. The combined effect of fludarabine monophosphate and radiation as well as gemcitabine and radiation on squamous carcinoma tumor cell lines in vitro. Int J Radiat Biol 2008;84:643-57.
    • (2008) Int J Radiat Biol , vol.84 , pp. 643-657
    • Nitsche, M.1    Christiansen, H.2    Hermann, R.M.3
  • 43
    • 0028670993 scopus 로고
    • Radiation induced membrane changes and programmed cell death: Possible interrelationships
    • Ojeda F, Diehl HA, Folch H. Radiation induced membrane changes and programmed cell death: possible interrelationships. Scanning Microsc 1994;3:645-51.
    • (1994) Scanning Microsc , vol.3 , pp. 645-651
    • Ojeda, F.1    Diehl, H.A.2    Folch, H.3
  • 44
    • 62749169989 scopus 로고    scopus 로고
    • A systemic review of the roles of n-3 fatty acids in health and disease
    • Riediger ND, Othman RA, Suh M, et al. A systemic review of the roles of n-3 fatty acids in health and disease. J Am Diet Assoc 2009;109:668-79.
    • (2009) J Am Diet Assoc , vol.109 , pp. 668-679
    • Riediger, N.D.1    Othman, R.A.2    Suh, M.3
  • 45
    • 3042749365 scopus 로고    scopus 로고
    • Eicosapentaenoic acid perturbs signalling via the NFkappaB transcriptional pathway in pancreatic tumour cells
    • Ross JA, Maingay JP, Fearon KC, et al. Eicosapentaenoic acid perturbs signalling via the NFkappaB transcriptional pathway in pancreatic tumour cells. Int J Oncol 2003;23:1733-8.
    • (2003) Int J Oncol , vol.23 , pp. 1733-1738
    • Ross, J.A.1    Maingay, J.P.2    Fearon, K.C.3
  • 46
    • 21644462730 scopus 로고    scopus 로고
    • Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells
    • DOI 10.1007/s10549-005-2415-z
    • Schley PD, Jijon HB, Robinson LE, et al. Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells. Breast Cancer Res Treat 2005;92:187-95. (Pubitemid 40933584)
    • (2005) Breast Cancer Research and Treatment , vol.92 , Issue.2 , pp. 187-195
    • Schley, P.D.1    Jijon, H.B.2    Robinson, L.E.3    Field, C.J.4
  • 47
    • 33745233026 scopus 로고    scopus 로고
    • Closely related colon cancer cell lines display different sensitivity to polyunsaturated fatty acids, accumulate different lipid classes and downregulate sterol regulatory elementbinding protein 1
    • Schonberg SA, Lundemo AG, Fladvad T, et al. Closely related colon cancer cell lines display different sensitivity to polyunsaturated fatty acids, accumulate different lipid classes and downregulate sterol regulatory elementbinding protein 1. FEBS J 2006;273:2749-65.
    • (2006) FEBS J , vol.273 , pp. 2749-2765
    • Schonberg, S.A.1    Lundemo, A.G.2    Fladvad, T.3
  • 48
    • 0031427092 scopus 로고    scopus 로고
    • Evidence that changes in Se-glutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids
    • DOI 10.1093/carcin/18.10.1897
    • Schonberg SA, Rudra PK, Noding R, et al. Evidence that changes in Seglutathione peroxidase levels affect the sensitivity of human tumour cell lines to n-3 fatty acids. Carcinogenesis 1997;18:1897-904. (Pubitemid 28132372)
    • (1997) Carcinogenesis , vol.18 , Issue.10 , pp. 1897-1904
    • Schonberg, S.A.1    Rudra, P.K.2    Noding, R.3    Skorpen, F.4    Bjerve, K.S.5    Krokan, H.E.6
  • 49
    • 0028906680 scopus 로고
    • Lack of radiosensitization after paclitaxel treatment of 3 human carcinoma cell-lines
    • Stromberg JS, Lee YJ, Armour EP, et al. Lack of radiosensitization after paclitaxel treatment of 3 human carcinoma cell-lines. Cancer 1995;75: 2262-8.
    • (1995) Cancer , vol.75 , pp. 2262-2268
    • Stromberg, J.S.1    Lee, Y.J.2    Armour, E.P.3
  • 50
    • 0029926812 scopus 로고    scopus 로고
    • Inhibition of lipolysis and muscle protein degradation by EPA in cancer cachexia
    • Tisdale MJ. Inhibition of lipolysis and muscle protein degradation by EPA in cancer cachexia. Nutrition 1996;12:S31-3.
    • (1996) Nutrition , vol.12
    • Tisdale, M.J.1
  • 51
    • 0031000091 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill
    • DOI 10.1007/s11745-997-0035-y
    • Vartak S, Robbins MEC, Spector AA. Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill. Lipids 1997;32:283-92. (Pubitemid 27131761)
    • (1997) Lipids , vol.32 , Issue.3 , pp. 283-292
    • Vartak, S.1    Robbins, M.E.C.2    Spector, A.A.3
  • 52
    • 33747776158 scopus 로고    scopus 로고
    • A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levels
    • von Schacky C. A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levels. Vasc Health Risk Manag 2006;2:251-62.
    • (2006) Vasc Health Risk Manag , vol.2 , pp. 251-262
    • Von Schacky, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.