9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cells

Biochemical and Biophysical Research Communications

Volumn 314, Issue 1, 2004, Pages 138-142

  Calonghi, N ^a   Cappadone, C ^a   Pagnotta, E ^a   Farruggia, G ^a   Buontempo, F ^a   Boga, C ^a   Brusa, G L ^a   Santucci, M A ^a   Masotti, L ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

9 HSA; Colon cancer; Endogenous lipid peroxidation products; P21WAF1; PCR

Indexed keywords

9 HYDROXYSTEARIC ACID; ANTINEOPLASTIC AGENT; PROTEIN P21; STEARIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN HT29; COLON CARCINOMA; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIPID PEROXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSLATION; UPREGULATION;

EID: 0347986519     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.12.066     Document Type: Article

References (26)

1. Slater T.F. Lipid peroxidation and cell division in normal and tumor tissue in Eicosanoid. Nigam S., McBrien D.C.H., Slater T.F. Lipid Peroxidation and Cancer. 1988;137-142 Springer-Verlag, Berlin.
2. Masotti L., Casali E., Galeotti T. Lipid peroxidation in tumor cells. Free Rad. Biol. Med. 4:1988;377-386.
3. Galeotti T., Masotti L., Borrello S., Casali E. Oxy-radical metabolism and control of tumor growth. Xenobiotica. 21:1991;1041-1051.
4. Masotti L., Casali E., Gesmundo N., Sartor G., Galeotti T., Borrello S., Piretti M.V., Pagliuca G. Lipid peroxidation in cancer cells: chemical and physical studies. Ann. NY Acad. Sci. 551:1988;47-58.
5. Cavalli G., Casali E., Spisni A., Masotti L. Identification of the peroxidation product hydroxystearic acid in Lewis lung carcinoma cells. Biochem. Biophys. Res. Commun. 3:1991;1260-1265.
6. Bertucci C., Hudaib M., Boga C., Calonghi N., Cappadone C., Masotti L. Gas chromatography/mass spectrometric assay of endogenous cellular lipid peroxidation products: quantitative analysis of 9- and 10-hydroxystearic acids. Rapid Commun. Mass Spectrom. 16:2002;859-864.
7. Casali E., Cavalli G., Spisni A., Masotti L. Effects of hydroxystearic acid on proliferation of C108 cells from Lewis lung carcinoma. Rec. Adv. Cell. Mol. Biol. 6:1992;245-250.
8. Masotti L., Casali E., Gesmundo N. Influence of hydroxystearic acid on in vitro cell proliferation. Mol. Aspects Med. 14:1993;209-215.
9. Gesmundo N., Casali E., Farruggia G., Spisni A., Masotti L. In vitro effects of hydroxystearic acid on the proliferation of HT29 and I407 cells. Biochem. Mol. Biol. Int. 33:1994;704-711.
10. Casali E., Gesmundo N., Farruggia G., Spisni A., Masotti L. Hydroxystearic acid effects on cdc2/histone H1 kinase activity in C108 cells. Biochem. Biophys. Res. Commun. 203:1994;1385-1391.
11. Pines J. Cyclins and cyclin-dependent kinase. Biochem. J. 308:1995;607-711.
12. Morgan D.O. Principles of CDK regulation. Nature. 374:1995;131-134.
13. Elledge S.J. Cell cycle checkpoints: preventing an identity crisis. Science. 274:1996;1664-1672.
14. Sherr C.J., Roberts J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9:1995;1149-1163.
15. Sherr C.J., Roberts J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1999;1501-1512.
16. El Deiry W.S., Tokino T., Velcovescu V.E., Levy D.B., Parson R., Trent J.M., Mercer W.E., Kinzler K.W., Vogelstein B. WAF 1, a potential mediator of p53 tumor suppression. Cell. 75:1993;817-825.
17. Coqueret O. New role for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol. 13:2003;65-70.
18. Xiong Y., Zhang H., Beach D. Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 7:1993;1572-1583.
19. El Deiry W.S., Harper S.W., O'Connor P.M., Velculescu V.E., Canma C.E., Jackman J., Pietenpol J.A., Burrell M., Hill D.E., Wang Y.et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 54:1994;1169-1174.
20. Macleod K.F., Sherry N., Hannon G., Beach D., Tokino T., Kinzler K., Vogelstein B., Jacks T. p53-dependent and independent expression of p21 during cell growth, differentiation and p DNA damage. Genes Dev. 9:1995;935-944.
21. Niculescu III A.B., Chen X., Smeets M., Hengst L., Prives C., Ree S.I. Effect of p21 (CIP1/WAF1) at both the G1/S and G2/M cell cycle transitions: pRB is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol. 18:1998;629-6243.
22. Waga S., Hannon G.J., Beach D., Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication with PCNA. Nature. 369:1994;574-578.
23. Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 61:1990;759-767.
24. Yamashita K., Yasuda H., Pines J., Yasumoto K., Nishitani H., Ohtsubo M., Hunter T., Sugimura T., Nishimoto T. Okadaic acid, a potent inhibitor of type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J. 9:1990;4331-4338.
25. Campanini F., Santucci M.A., Brusa G., Pattacini L., Arpinati M., Rondelli D., Gamberi B., Barbieri E., Babini L., Tura S. Expression of P21(WAF1/CIP1/SID1) cyclin-dependent kinase inhibitor in hematopoietic progenitor cells. Gene. 273:2001;173-180.
26. Johnson D.G., Walker C.L. Cyclin and cell cycle checkpoints. Annu. Rev. Pharmacol. Toxicol. 39:1999;295-312.