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Volumn 181, Issue 4, 2009, Pages 1885-1893

Mechanisms of Action of Eicosapentaenoic Acid in Bladder Cancer Cells In Vitro: Alterations in Mitochondrial Metabolism, Reactive Oxygen Species Generation and Apoptosis Induction

Author keywords

apoptosis; bladder; bladder neoplasms; cardiolipins; eicosapentaenoic acid

Indexed keywords

CARDIOLIPIN; CASPASE 3; ICOSAPENTAENOIC ACID; LIPID PEROXIDE; MEMBRANE PHOSPHOLIPID; REACTIVE OXYGEN METABOLITE;

EID: 62049084741     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2008.11.092     Document Type: Article
Times cited : (22)

References (20)
  • 1
    • 0022969335 scopus 로고
    • Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids
    • Bégin M.E., Ells G., Das U.N., and Horrobin D.F. Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids. J Natl Cancer Inst 77 (1986) 1053
    • (1986) J Natl Cancer Inst , vol.77 , pp. 1053
    • Bégin, M.E.1    Ells, G.2    Das, U.N.3    Horrobin, D.F.4
  • 2
    • 0025652155 scopus 로고
    • Gamma-linolenic acid, arachidonic acid, and eicosapentaenoic acid as potential anticancer drugs
    • Das U.N. Gamma-linolenic acid, arachidonic acid, and eicosapentaenoic acid as potential anticancer drugs. Nutrition 6 (1990) 429
    • (1990) Nutrition , vol.6 , pp. 429
    • Das, U.N.1
  • 3
    • 0028344160 scopus 로고
    • Greater sensitivity of human multidrug-resistant (mdr) cancer cells to polyunsaturated fatty acids than their non-mdr counterparts
    • Weber J.M., Sircar S., and Bégin M.E. Greater sensitivity of human multidrug-resistant (mdr) cancer cells to polyunsaturated fatty acids than their non-mdr counterparts. J Natl Cancer Inst 86 (1994) 638
    • (1994) J Natl Cancer Inst , vol.86 , pp. 638
    • Weber, J.M.1    Sircar, S.2    Bégin, M.E.3
  • 4
    • 0032832971 scopus 로고    scopus 로고
    • Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines
    • Davies C.L., Loizidou M., Cooper A.J., and Taylor I. Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. Eur J Cancer 35 (1999) 1534
    • (1999) Eur J Cancer , vol.35 , pp. 1534
    • Davies, C.L.1    Loizidou, M.2    Cooper, A.J.3    Taylor, I.4
  • 5
    • 0035980762 scopus 로고    scopus 로고
    • Gamma-linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells
    • Colquhoun A., and Schumacher R.I. Gamma-linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. Biochim Biophys Acta 1533 (2001) 207
    • (2001) Biochim Biophys Acta , vol.1533 , pp. 207
    • Colquhoun, A.1    Schumacher, R.I.2
  • 6
    • 0037071863 scopus 로고    scopus 로고
    • Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour
    • Colquhoun A. Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. Biochim Biophys Acta 1583 (2002) 74
    • (2002) Biochim Biophys Acta , vol.1583 , pp. 74
    • Colquhoun, A.1
  • 7
    • 0036662310 scopus 로고    scopus 로고
    • Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study
    • Harris N.M., Crook T.J., Dyer J.P., Solomon L.Z., Bass P., Cooper A.J., et al. Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. Eur Urol 42 (2002) 39
    • (2002) Eur Urol , vol.42 , pp. 39
    • Harris, N.M.1    Crook, T.J.2    Dyer, J.P.3    Solomon, L.Z.4    Bass, P.5    Cooper, A.J.6
  • 8
    • 0037214884 scopus 로고    scopus 로고
    • Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma
    • Harris N.M., Anderson W.R., Lwaleed B.A., Cooper A.J., Birch B.R., and Solomon L.Z. Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. Cancer 97 (2003) 71
    • (2003) Cancer , vol.97 , pp. 71
    • Harris, N.M.1    Anderson, W.R.2    Lwaleed, B.A.3    Cooper, A.J.4    Birch, B.R.5    Solomon, L.Z.6
  • 9
    • 33750483260 scopus 로고    scopus 로고
    • Meglumine Eicosapentaenoic acid (MeEPA) a new soluble omega-3 fatty acid formulation: in vitro bladder cancer cytotoxicity tests in combination with epirubicin and mitomycin
    • Mackie S.J., Sharma D.M., Cooper A.J., Harris N.M., and Lwaleed B.A. Meglumine Eicosapentaenoic acid (MeEPA) a new soluble omega-3 fatty acid formulation: in vitro bladder cancer cytotoxicity tests in combination with epirubicin and mitomycin. Prostaglandins Leukot Essent Fatty Acids 75 (2006) 367
    • (2006) Prostaglandins Leukot Essent Fatty Acids , vol.75 , pp. 367
    • Mackie, S.J.1    Sharma, D.M.2    Cooper, A.J.3    Harris, N.M.4    Lwaleed, B.A.5
  • 10
    • 0030953449 scopus 로고    scopus 로고
    • Metabolic fate and effects of saturated and unsaturated fatty acids in Hep2 human larynx tumor cells
    • Colquhoun A., and Curi R. Metabolic fate and effects of saturated and unsaturated fatty acids in Hep2 human larynx tumor cells. Biochem Mol Biol Int 41 (1997) 597
    • (1997) Biochem Mol Biol Int , vol.41 , pp. 597
    • Colquhoun, A.1    Curi, R.2
  • 11
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J., Lees M., and Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226 (1957) 497
    • (1957) J Biol Chem , vol.226 , pp. 497
    • Folch, J.1    Lees, M.2    Sloane-Stanley, G.H.3
  • 12
    • 0025191311 scopus 로고
    • Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells
    • Board M., Humm S., and Newsholme E.A. Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells. Biochem J 265 (1990) 503
    • (1990) Biochem J , vol.265 , pp. 503
    • Board, M.1    Humm, S.2    Newsholme, E.A.3
  • 13
    • 0028978268 scopus 로고
    • High Km glucose-phosphorylating (glucokinase) activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose
    • Board M., Colquhoun A., and Newsholme E.A. High Km glucose-phosphorylating (glucokinase) activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose. Cancer Res 55 (1995) 3278
    • (1995) Cancer Res , vol.55 , pp. 3278
    • Board, M.1    Colquhoun, A.2    Newsholme, E.A.3
  • 14
    • 33747674312 scopus 로고    scopus 로고
    • Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants
    • Helland I.B., Saugstad O.D., Saarem K., Van Houwelingen A.C., Nylander G., and Drevon C.A. Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants. J Matern Fetal Neonatal Med 19 (2006) 397
    • (2006) J Matern Fetal Neonatal Med , vol.19 , pp. 397
    • Helland, I.B.1    Saugstad, O.D.2    Saarem, K.3    Van Houwelingen, A.C.4    Nylander, G.5    Drevon, C.A.6
  • 15
    • 0041303668 scopus 로고    scopus 로고
    • Protective role of glucose-6-phosphate dehydrogenase activity in the metabolic response of C6 rat glioma cells to polyunsaturated fatty acid exposure
    • Ramos K.L., and Colquhoun A. Protective role of glucose-6-phosphate dehydrogenase activity in the metabolic response of C6 rat glioma cells to polyunsaturated fatty acid exposure. Glia 43 (2003) 149
    • (2003) Glia , vol.43 , pp. 149
    • Ramos, K.L.1    Colquhoun, A.2
  • 16
    • 0034001931 scopus 로고    scopus 로고
    • Uptake and activation of eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos cells dying from apoptosis
    • Finstad H.S., Dyrendal H., Myhrstad M.C., Heimli H., and Drevon C.A. Uptake and activation of eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos cells dying from apoptosis. J Lipid Res 41 (2000) 554
    • (2000) J Lipid Res , vol.41 , pp. 554
    • Finstad, H.S.1    Dyrendal, H.2    Myhrstad, M.C.3    Heimli, H.4    Drevon, C.A.5
  • 17
    • 39149098440 scopus 로고    scopus 로고
    • Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis
    • Jiang J., Huang Z., Zhao Q., Feng W., Belikova N.A., and Kagan V.E. Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis. Biochem Biophys Res Commun 368 (2008) 145
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 145
    • Jiang, J.1    Huang, Z.2    Zhao, Q.3    Feng, W.4    Belikova, N.A.5    Kagan, V.E.6
  • 18
    • 34250789163 scopus 로고    scopus 로고
    • Role of cardiolipin in cytochrome c release from mitochondria
    • Ott M., Zhivotovsky B., and Orrenius S. Role of cardiolipin in cytochrome c release from mitochondria. Cell Death Differ 14 (2007) 1243
    • (2007) Cell Death Differ , vol.14 , pp. 1243
    • Ott, M.1    Zhivotovsky, B.2    Orrenius, S.3
  • 19
    • 34247482333 scopus 로고    scopus 로고
    • Cardiolipin: setting the beat of apoptosis
    • Gonzalvez F., and Gottlieb E. Cardiolipin: setting the beat of apoptosis. Apoptosis 12 (2007) 877
    • (2007) Apoptosis , vol.12 , pp. 877
    • Gonzalvez, F.1    Gottlieb, E.2
  • 20
    • 17244364476 scopus 로고    scopus 로고
    • Altered lipid profile and changes in uroplakin properties of rat urothelial plasma membrane with diets of different lipid composition
    • Bongiovanni G.A., Eynard A.R., and Calderón R.O. Altered lipid profile and changes in uroplakin properties of rat urothelial plasma membrane with diets of different lipid composition. Mol Cell Biochem 271 (2005) 69
    • (2005) Mol Cell Biochem , vol.271 , pp. 69
    • Bongiovanni, G.A.1    Eynard, A.R.2    Calderón, R.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.