Induction of apoptosis and inhibition of PI3K/Akt pathway in PC-3 and LNCaP prostate cancer cells by ethanolic neem leaf extract

Journal of Ethnopharmacology

Volumn 134, Issue 3, 2011, Pages 644-650

  Gunadharini, Dharmalingam N ^a   Elumalai, Perumal ^a   Arunkumar, Ramachandran ^a   Senthilkumar, Kalimuthu ^a   Arunakaran, Jagadeesan ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Akt; Apoptosis; Cell cycle; Ethanolic neem leaf extract; Neem; Prostate cancer

Indexed keywords

AZADIRACHTA INDICA EXTRACT; CASPASE 3; CYCLIN D1; CYTOCHROME C; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P21;

APOPTOSIS; ARTICLE; AZADIRACHTA INDICA; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IN VITRO STUDY; PLANT LEAF; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; AZADIRACHTA; BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA PRIMERS; ETHANOL; HUMANS; IN SITU NICK-END LABELING; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PLANT LEAVES; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

AZADIRACHTA INDICA;

EID: 79954424851     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2011.01.015     Document Type: Article

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