Evaluation of Azadirachta indica leaf fractions for in vitro antioxidant potential and in vivo modulation of biomarkers of chemoprevention in the hamster buccal pouch carcinogenesis model

Food and Chemical Toxicology

Volumn 46, Issue 7, 2008, Pages 2332-2343

  Manikandan, P ^a   Letchoumy, P Vidjaya ^a   Gopalakrishnan, M ^a   Nagini, S ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Angiogenesis; Antioxidants; Apoptosis; Chemoprevention; Hamster buccal pouch carcinogenesis; Neem; Xenobiotic metabolizing enzymes

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; ANTIOXIDANT; AZADIRACHTA INDICA EXTRACT; BIOLOGICAL MARKER; CYTOCHROME P450; DIMETHYLBENZ[A]ANTHRACENE; FREE RADICAL; ISOENZYME; METHANOL; PLANT MEDICINAL PRODUCT; SCAVENGER; XENOBIOTIC AGENT;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AZADIRACHTA INDICA; CANCER CELL; CELL PROLIFERATION; CHEEK POUCH; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; FACE CANCER; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIPID OXIDATION; MALE; MEDICINAL PLANT; NONHUMAN; OXIDATION; PLANT LEAF; PROTEIN EXPRESSION; UPREGULATION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; APOPTOSIS; AZADIRACHTA; BIOLOGICAL MARKERS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; MALE; MESOCRICETUS; MOUTH NEOPLASMS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES;

AZADIRACHTA INDICA; CRICETINAE;

EID: 44749083758     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.03.013     Document Type: Article

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