Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25

Journal of Neurochemistry

Volumn 117, Issue 3, 2011, Pages 504-515

  Sato, Ko ^a   Minegishi, Seiji ^a   Takano, Jiro ^a   Plattner, Florian ^b   Saito, Taro ^a   Asada, Akiko ^a   Kawahara, Hiroyuki ^c   Iwata, Nobuhisa ^a   Saido, Takaomi C ^a   Hisanaga, Shin Ichi ^a  

^a TOKYO METROPOLITAN UNIVERSITY   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Alzheimer's disease; calpain; calpastatin; cyclin dependent kinase 5

Indexed keywords

CALCIUM ION; CALPAIN; CALPASTATIN; CYCLIN DEPENDENT KINASE 5; PROTEASOME; PROTEIN P25; PROTEIN P35;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN LEVEL; CASE REPORT; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; KNOCKOUT GENE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; WILD TYPE;

ALZHEIMER DISEASE; ANIMALS; BRAIN; CALCIUM; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; REPERFUSION INJURY;

MUS;

EID: 79954423743     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07222.x     Document Type: Article

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