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Volumn 79, Issue 4, 2011, Pages 204-212

The role of the glutamatergic system in pathophysiology and pharmacotherapy for depression: Preclinical and clinical data;Die Bedeutung des glutamatergen Systems farmakotherapie der Depression: präklinische und klinische Daten

Author keywords

depression; glia cells; glutamate; ketamine; NMDA receptor

Indexed keywords

GLUTAMIC ACID;

EID: 79954421027     PISSN: 07204299     EISSN: 14393522     Source Type: Journal    
DOI: 10.1055/s-0029-1245770     Document Type: Article
Times cited : (4)

References (121)
  • 2
    • 19844376410 scopus 로고    scopus 로고
    • Size and burden of depressive disorders in Europe
    • DOI 10.1016/j.euroneuro.2005.04.008, PII S0924977X05000714, Size and Burden of Mental Disorders in Europe
    • Paykel E S., Brugha T, Fryers T. Size and burden of depressive disorders in Europe. Eur Neuropsychopharmacol 2005 15 411-423 (Pubitemid 40943545)
    • (2005) European Neuropsychopharmacology , vol.15 , Issue.4 , pp. 411-423
    • Paykel, E.S.1    Brugha, T.2    Fryers, T.3
  • 3
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
    • DOI 10.1001/archpsyc.62.6.617
    • Kessler R C., Chiu W T., Demler O et al. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005 62 617-627 (Pubitemid 40973437)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.6 , pp. 617-627
    • Kessler, R.C.1    Wai, T.C.2    Demler, O.3    Walters, E.E.4
  • 5
    • 10044270015 scopus 로고    scopus 로고
    • Therapeutic alternatives for difficult-to-treat depression: A narrative review of the state of the evidence
    • Thase M E. Therapeutic alternatives for difficult-to-treat depression: a narrative review of the state of the evidence. CNS Spectr 2004 9 808-821 (Pubitemid 39602937)
    • (2004) CNS Spectrums , vol.9 , Issue.11 , pp. 808-821
    • Thase, M.E.1
  • 6
    • 33747194625 scopus 로고    scopus 로고
    • Augmentation and combination strategies for depression
    • DeBattista C. Augmentation and combination strategies for depression. J Psychopharmacol 2006 20 11-18
    • (2006) J Psychopharmacol , vol.20 , pp. 11-18
    • Debattista, C.1
  • 7
    • 33646078939 scopus 로고    scopus 로고
    • Current status of augmentation and combination treatments for major depressive disorder: A literature review and a proposal for a novel approach to improve practice
    • Fava M, Rush A J. Current status of augmentation and combination treatments for major depressive disorder: a literature review and a proposal for a novel approach to improve practice. Psychother Psychosom 2006 75 139-153
    • (2006) Psychother Psychosom , vol.75 , pp. 139-153
    • Fava, M.1    Rush, A.J.2
  • 9
    • 27444434056 scopus 로고    scopus 로고
    • Beyond monoamines: Glutamatergic function in mood disorders
    • Kugaya A, Sanacora G. Beyond monoamines: glutamatergic function in mood disorders. CNS Spectrom 2005 10 808-819 (Pubitemid 41531934)
    • (2005) CNS Spectrums , vol.10 , Issue.10 , pp. 808-819
    • Kugaya, A.1    Sanacora, G.2
  • 10
    • 70349513258 scopus 로고    scopus 로고
    • Emerging role of glutamate in the pathophysiology of major depressive disorder
    • Hashimoto K. Emerging role of glutamate in the pathophysiology of major depressive disorder. Brain Res Rev 2009 61 105-123
    • (2009) Brain Res Rev , vol.61 , pp. 105-123
    • Hashimoto, K.1
  • 13
    • 1642307858 scopus 로고    scopus 로고
    • Regulation of MAPK/ERK phosphorylation via ionotropic glutamate receptors in cultured rat striatal neurons
    • DOI 10.1111/j.1460-9568.2004.03223.x
    • Mao L, Tang Q et al. Regulation of MAPK/ERK phosphorylation via ionotropic glutamate receptors in cultured rat striatal neurons. Eur J Neurosci 2004 19 1207-1216 (Pubitemid 38387198)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.5 , pp. 1207-1216
    • Mao, L.1    Tang, Q.2    Samdani, S.3    Liu, Z.4    Wang, J.Q.5
  • 14
    • 14944350207 scopus 로고    scopus 로고
    • Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons
    • Mao L, Yang L et al. Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons. J Biol Chem 2005 280 12602-12610
    • (2005) J Biol Chem , vol.280 , pp. 12602-12610
    • Mao, L.1    Yang, L.2
  • 15
    • 0036236746 scopus 로고    scopus 로고
    • What a privilege to reside at the synapse: NMDA receptor signaling to CREB
    • DOI 10.1038/nn0502-389
    • Riccio A, Ginty D D. What a privilege to reside at the synapse: NMDA receptor signaling to CREB. Nature Neuroscience 2002 5 389-390 (Pubitemid 34454237)
    • (2002) Nature Neuroscience , vol.5 , Issue.5 , pp. 389-390
    • Riccio, A.1    Ginty, D.D.2
  • 16
    • 79954425805 scopus 로고    scopus 로고
    • Altering BDNF expression by genetics and/or environment: Impact for emotional and depression-like behaviour in laboratory mice
    • 17 Jul [Epub ahead of print]
    • Chourbaji S, Brandwein C, Gass P. Altering BDNF expression by genetics and/or environment: Impact for emotional and depression-like behaviour in laboratory mice. Neurosci Biobehav Rev 17 Jul 2010 [Epub ahead of print]
    • (2010) Neurosci Biobehav Rev
    • Chourbaji, S.1    Brandwein, C.2    Gass, P.3
  • 17
    • 77949652896 scopus 로고    scopus 로고
    • Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker for affective disorders
    • Epub 2009 Dec 9
    • Gass P, Hellweg R. Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker for affective disorders? Int J Neuropsychopharmacol 2010 Epub 2009 Dec 9 13 1-4
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 1-4
    • Gass, P.1    Hellweg, R.2
  • 18
    • 41149134908 scopus 로고    scopus 로고
    • Serum concentrations of nerve growth factor and brain-derived neurotrophic factor in depressed patients before and after antidepressant treatment
    • DOI 10.1055/s-2007-1004594
    • Hellweg R, Ziegenhorn A, Heuser I et al. Serum concentrations of nerve growth factor and brain-derived neurotrophic factor in depressed patients before and after antidepressant treatment. Pharmacopsychiatry 2008 41 66-71 (Pubitemid 351427525)
    • (2008) Pharmacopsychiatry , vol.41 , Issue.2 , pp. 66-71
    • Hellweg, R.1    Ziegenhorn, A.2    Heuser, I.3    Deuschle, M.4
  • 19
    • 0036241207 scopus 로고    scopus 로고
    • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
    • DOI 10.1038/nn835
    • Hardingham G E., Fukunaga Y, Bading H. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 2002 5 405-414 (Pubitemid 34454245)
    • (2002) Nature Neuroscience , vol.5 , Issue.5 , pp. 405-414
    • Hardingham, G.E.1    Fukunaga, Y.2    Bading, H.3
  • 20
    • 33645837486 scopus 로고    scopus 로고
    • Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons
    • Ivanov A, Pellegrino C, Rama S et al. Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons. J Physiol 2006 572 789-798
    • (2006) J Physiol , vol.572 , pp. 789-798
    • Ivanov, A.1    Pellegrino, C.2    Rama, S.3
  • 21
    • 0036241207 scopus 로고    scopus 로고
    • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
    • DOI 10.1038/nn835
    • Hardingham G E., Fukunaga Y, Bading H. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 2002 5 405-414 (Pubitemid 34454245)
    • (2002) Nature Neuroscience , vol.5 , Issue.5 , pp. 405-414
    • Hardingham, G.E.1    Fukunaga, Y.2    Bading, H.3
  • 23
    • 0027363029 scopus 로고
    • Plasma and platelet excitatory amino acids in psychiatric disorders
    • Altamura C A., Mauri M C., Ferrara A et al. Plasma and platelet excitatory amino acids in psychiatric disorders. Am J Psychiatry 1993 150 1713-1731
    • (1993) Am J Psychiatry , vol.150 , pp. 1713-1731
    • Altamura, C.A.1    Mauri, M.C.2    Ferrara, A.3
  • 26
    • 0031959460 scopus 로고    scopus 로고
    • Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: Modulation by treatment with antidepressants and prediction of clinical responsivity
    • Maes M, Verkerk R, Vandoolaeghe E et al. Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity. Acta Psychiatr Scand 1998 97 302-308 (Pubitemid 28179268)
    • (1998) Acta Psychiatrica Scandinavica , vol.97 , Issue.4 , pp. 302-308
    • Maes, M.1    Verkerk, R.2    Vandoolaeghe, E.3    Lin, A.4    Scharpe, S.5
  • 27
    • 35848939420 scopus 로고    scopus 로고
    • Increased Levels of Glutamate in Brains from Patients with Mood Disorders
    • DOI 10.1016/j.biopsych.2007.03.017, PII S0006322307002752, Depression: New Perspectives on Treatment and Etiology
    • Hashimoto K, Sawa A, Iyo M. Increased levels of glutamate in brains from patients with mood disorders. Biol Psychiatry 2007 62 1310-1316 (Pubitemid 350060893)
    • (2007) Biological Psychiatry , vol.62 , Issue.11 , pp. 1310-1316
    • Hashimoto, K.1    Sawa, A.2    Iyo, M.3
  • 29
    • 0035903772 scopus 로고    scopus 로고
    • Asymmetrical reductions of hippocampal NMDARI glutamate receptor mRNA in the psychoses
    • Law A J., Deakin J F. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. NeuroReport 2001 12 2971-2974 (Pubitemid 32882018)
    • (2001) NeuroReport , vol.12 , Issue.13 , pp. 2971-2974
    • Law, A.J.1    Deakin, J.F.W.2
  • 30
    • 8644282826 scopus 로고    scopus 로고
    • The NR1 subunit of the glutamate/NMDA receptor in the superior temporal cortex in schizophrenia and affective disorders
    • DOI 10.1016/j.neulet.2004.09.035, PII S0304394004011693
    • Nudmamud-Thanoi S, Reynolds G P. The NR 1 subunit of the glutamate/NMDA receptor in the superior temporal cortex in schizophrenia and affective disorders. Neurosci Lett 2004 372 173-177 (Pubitemid 39505251)
    • (2004) Neuroscience Letters , vol.372 , Issue.1-2 , pp. 173-177
    • Nudmamud-Thanoi, S.1    Reynolds, G.P.2
  • 32
    • 58149357209 scopus 로고    scopus 로고
    • Reduced levels of NR 2A and NR 2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression
    • Feyissa A M., Chandran A, Stockmeier C A. et al. Reduced levels of NR 2A and NR 2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression. Prog Neuropsychopharmacol Biol Psychiatry 2009 33 70-75
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 70-75
    • Feyissa, A.M.1    Chandran, A.2    Stockmeier, C.A.3
  • 33
    • 70349518522 scopus 로고    scopus 로고
    • Glutamate receptors expression in postmortem brain from depressed subjects
    • Karolewicz B, Feyissa A M., Chandran A et al. Glutamate receptors expression in postmortem brain from depressed subjects. Biol Psychiatry 2009 65 177
    • (2009) Biol Psychiatry , vol.65 , pp. 177
    • Karolewicz, B.1    Feyissa, A.M.2    Chandran, A.3
  • 34
    • 70349551371 scopus 로고    scopus 로고
    • Abnormal prefrontal glutamatergic and GABAeric systems in mood and anxiety disorders
    • Hasler G. Abnormal prefrontal glutamatergic and GABAeric systems in mood and anxiety disorders. Biol Psychiatry 2009 65 176-177
    • (2009) Biol Psychiatry , vol.65 , pp. 176-177
    • Hasler, G.1
  • 35
    • 23844444829 scopus 로고    scopus 로고
    • Elevated levels of the NR2C subunit of the NMDA receptor in the locus coeruleus in depression
    • DOI 10.1038/sj.npp.1300781
    • Karolewicz B, Stockmeier C A., Ordway G A. et al. Elevated levels of the NR 2C subunit of the NMDA receptor in the locus coeruleus in depression. Neuropsychopharmacol 2005 30 1557-1567 (Pubitemid 41153128)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.8 , pp. 1557-1567
    • Karolewicz, B.1    Stockmeier, C.A.2    Ordway, G.A.3
  • 36
    • 0035878137 scopus 로고    scopus 로고
    • Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorder
    • DOI 10.1016/S0361-9230(01)00523-8, PII S0361923001005238
    • Meador-Woodruff J H., Hogg Jr A J., Smith R E. Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorder. Brain Res Bull 2001 55 631-640 (Pubitemid 32888382)
    • (2001) Brain Research Bulletin , vol.55 , Issue.5 , pp. 631-640
    • Meador-Woodruff, J.H.1    Hogg Jr., A.J.2    Smith, R.E.3
  • 39
    • 0342546475 scopus 로고    scopus 로고
    • Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study
    • DOI 10.1016/S0006-3223(99)00159-6, PII S0006322399001596
    • Auer D P., Putz B, Kraft E et al. Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study. Biol Psychiatry 2000 47 305-313 (Pubitemid 30109243)
    • (2000) Biological Psychiatry , vol.47 , Issue.4 , pp. 305-313
    • Auer, D.P.1    Putz, B.2    Kraft, E.3    Lipinski, B.4    Schill, J.5    Holsboer, F.6
  • 40
    • 34249079805 scopus 로고    scopus 로고
    • Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy
    • DOI 10.1038/sj.npp.1301248, PII 1301248
    • Ajilore O, Haroon E, Kumaran S et al. Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy. Neuropsychopharmacology 2007 32 1224-1231 (Pubitemid 46788852)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.6 , pp. 1224-1231
    • Ajilore, O.1    Haroon, E.2    Kumaran, S.3    Darwin, C.4    Binesh, N.5    Mintz, J.6    Miller, J.7    Thomas, M.A.8    Kumar, A.9
  • 41
    • 33846877408 scopus 로고    scopus 로고
    • Reduced prefrontal glutamate/glutamine and γ-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy
    • DOI 10.1001/archpsyc.64.2.193
    • Hasler G, Veen J W., Tumonis T van der et al. Reduced prefrontal glutamate/glutamine and -aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy. Arch Gen Psychiatry 2007 64 193-200 (Pubitemid 46220776)
    • (2007) Archives of General Psychiatry , vol.64 , Issue.2 , pp. 193-200
    • Hasler, G.1    Van Der Veen, J.W.2    Tumonis, T.3    Meyers, N.4    Shen, J.5    Drevets, W.C.6
  • 42
    • 66449108573 scopus 로고    scopus 로고
    • Proton MR spectroscopy of the hippocampus at 3T in patients with unipolar major depressive disorder: Correlates and predictors of treatment responses
    • Block W, Träber F, Widdern O von et al. Proton MR spectroscopy of the hippocampus at 3T in patients with unipolar major depressive disorder: correlates and predictors of treatment responses. Int J Neuropsychopharmacol 2009 12 415-422
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 415-422
    • Block, W.1    Träber, F.2    Von, W.O.3
  • 43
    • 1842533140 scopus 로고    scopus 로고
    • The Interrelationship of Neuroticism, Sex, and Stressful Life Events in the Prediction of Episodes of Major Depression
    • DOI 10.1176/appi.ajp.161.4.631
    • Kendler K S., Kuhn J, Prescott C A. The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression. Am J Psychiatry 2004 161 631-636 (Pubitemid 38445506)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.4 , pp. 631-636
    • Kendler, K.S.1    Kuhn, J.2    Prescott, C.A.3
  • 44
    • 0034667334 scopus 로고    scopus 로고
    • The possibility of neurotoxicity in the hippocampus in major depression: A primer on neuron death
    • Sapolsky R M. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biol Psychiatry 2000 48 755-765
    • (2000) Biol Psychiatry , vol.48 , pp. 755-765
    • Sapolsky, R.M.1
  • 45
    • 0037093781 scopus 로고    scopus 로고
    • Stress activation of glutamate neurotransmission in the prefrontal cortex: Implications for dopamine-associated psychiatric disorders
    • DOI 10.1016/S0006-3223(01)01362-2, PII S0006322301013622
    • Moghaddam B. Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders. Biol Psychiatry 2002 51 775-787 (Pubitemid 34451064)
    • (2002) Biological Psychiatry , vol.51 , Issue.10 , pp. 775-787
    • Moghaddam, B.1
  • 46
    • 0031020921 scopus 로고    scopus 로고
    • Temporal dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: Effects of pretreatment with saline or diazepam
    • DOI 10.1016/S0306-4522(96)00435-6, PII S0306452296004356
    • Bagley J, Moghaddam B. Temporal dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: effects of pretreatment with saline or diazepam. Neuroscience 1997 77 65-73 (Pubitemid 27060307)
    • (1997) Neuroscience , vol.77 , Issue.1 , pp. 65-73
    • Bagley, J.1    Moghaddam, B.2
  • 47
    • 34548046778 scopus 로고    scopus 로고
    • Chronic Unpredictable Stress Decreases Cell Proliferation in the Cerebral Cortex of the Adult Rat
    • DOI 10.1016/j.biopsych.2007.02.006, PII S0006322307000996
    • Banasr M, Valentine G W., Li X Y. et al. Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat. Biol Psychiatry 2007 62 496-504 (Pubitemid 47284039)
    • (2007) Biological Psychiatry , vol.62 , Issue.5 , pp. 496-504
    • Banasr, M.1    Valentine, G.W.2    Li, X.-Y.3    Gourley, S.L.4    Taylor, J.R.5    Duman, R.S.6
  • 48
    • 34447120290 scopus 로고    scopus 로고
    • What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated?
    • DOI 10.1007/s00406-007-0728-0
    • Czeh B, Lucassen P J. What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated? Eur Arch Psychiatry Clin Neurosci 2007 257 250-60 (Pubitemid 47301403)
    • (2007) European Archives of Psychiatry and Clinical Neuroscience , vol.257 , Issue.5 , pp. 250-260
    • Czeh, B.1    Lucassen, P.J.2
  • 49
    • 34250357250 scopus 로고    scopus 로고
    • Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: Hemispheric asymmetry and reversal by fluoxetine treatment
    • DOI 10.1038/sj.npp.1301275, PII 1301275
    • Czeh B, Muller-Keuker J I., Rygula R et al. Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment. Neuropsychopharmacology 2007 32 1490-1503 (Pubitemid 46920152)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.7 , pp. 1490-1503
    • Czeh, B.1    Muller-Keuker, J.I.H.2    Rygula, R.3    Abumaria, N.4    Hiemke, C.5    Domenici, E.6    Fuchs, E.7
  • 50
    • 0027432521 scopus 로고
    • Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid
    • Nowak G, Trullas R, Layer R T. et al. Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. J Pharmacol Exp Ther 1993 265 1380-1386 (Pubitemid 23321045)
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.265 , Issue.3 , pp. 1380-1386
    • Nowak, G.1    Trullas, R.2    Layer, R.T.3    Skolnick, P.4    Paul, I.A.5
  • 51
    • 0030066153 scopus 로고    scopus 로고
    • Adaptation of cortical but not hippocampal NMDA receptors after chronic citalopram treatment
    • DOI 10.1016/0014-2999(95)00585-4
    • Nowak G, Li Y, Paul I A. Adaptation of cortical but not hippocampal NMDA receptors after chronic citalopram treatment. Eur J Pharmacol 1996 295 75-85 (Pubitemid 26027124)
    • (1996) European Journal of Pharmacology , vol.295 , Issue.1 , pp. 75-85
    • Nowak, G.1    Li, Y.2    Paul, I.A.3
  • 52
    • 0032567795 scopus 로고    scopus 로고
    • Adaptation of cortical NMDA receptors by chronic treatment with specific serotonin reuptake inhibitors
    • DOI 10.1016/S0014-2999(97)01589-6, PII S0014299997015896
    • Nowak G, Legutko B, Skolnick P et al. Adaptation of cortical NMDA receptors by chronic treatment with specific serotonin reuptake inhibitors. Eur J Pharmacol 1998 342 367-370 (Pubitemid 28149993)
    • (1998) European Journal of Pharmacology , vol.342 , Issue.2-3 , pp. 367-370
    • Nowak, G.1    Legutko, B.2    Skolnick, P.3    Popik, P.4
  • 54
    • 0030032399 scopus 로고    scopus 로고
    • Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: Implications for the pharmacotherapy of depression
    • Skolnick P, Layer R T., Popik P et al. Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression. Pharmacopsychiatry 1996 29 23-26 (Pubitemid 26072654)
    • (1996) Pharmacopsychiatry , vol.29 , Issue.1 , pp. 23-26
    • Skolnick, P.1    Layer, R.T.2    Popik, P.3    Nowak, G.4    Paul, I.A.5    Trullas, R.6
  • 55
    • 0031751159 scopus 로고    scopus 로고
    • Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain: A quantitative in situ hybridization study
    • Boyer P A., Skolnick P, Fossom L H. Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. J Mol Neurosci 1998 10 219-233 (Pubitemid 28427889)
    • (1998) Journal of Molecular Neuroscience , vol.10 , Issue.3 , pp. 219-233
    • Boyer, P.-A.1    Skolnick, P.2    Fossom, L.H.3
  • 56
    • 0034638488 scopus 로고    scopus 로고
    • Imipramine and phenelzine decrease glutamate overflow in the prefrontal cortex - A possible mechanism of neuroprotection in major depression
    • Michael-Titus A T., Bains S, Jeetle J et al. Imipramine and phenelzine decrease glutamate overflow in the prefrontal cortex - a possible mechanism of neuroprotection in major depression? Neuroscience 2000 100 681-684
    • (2000) Neuroscience , vol.100 , pp. 681-684
    • Michael-Titus, A.T.1    Bains, S.2    Jeetle, J.3
  • 57
    • 43049093681 scopus 로고    scopus 로고
    • Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex
    • Tokarski K, Bobula B, Wabno J et al. Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex. Neuroscience 2008 153 789-795
    • (2008) Neuroscience , vol.153 , pp. 789-795
    • Tokarski, K.1    Bobula, B.2    Wabno, J.3
  • 58
    • 0034502510 scopus 로고    scopus 로고
    • Effect of acute and chronic administration of citalopram on glutamate and aspartate release in the rat prefrontal cortex
    • Golembiowska K, Dziubina A. Effect of acute and chronic administration of citalopram on glutamate and aspartate release in the rat prefrontal cortex. Pol J Pharmacol 2000 52 441-448 (Pubitemid 32045907)
    • (2000) Polish Journal of Pharmacology , vol.52 , Issue.6 , pp. 441-448
    • Golembiowska, K.1    Dziubina, A.2
  • 59
    • 0024625331 scopus 로고
    • Open channel block of NMDA receptor responses evoked by tricyclic antidepressants
    • Sernagor E, Kuhn D, Vyklicky Jr L et al. Open channel block of NMDA receptor responses evoked by tricyclic antidepressants. Neuron 1989 2 1221-1227
    • (1989) Neuron , vol.2 , pp. 1221-1227
    • Sernagor, E.1    Kuhn, D.2    Vyklicky Jr., L.3
  • 60
    • 0026684806 scopus 로고
    • Amitriptyline, desipramine, cyproheptadine and carbamazepine, in concentrations used therapeutically, reduce kainate- and Nmethyl- D-aspartate-induced intracellular Ca2 + levels in neuronal culture
    • Cai Z, McCaslin P P. Amitriptyline, desipramine, cyproheptadine and carbamazepine, in concentrations used therapeutically, reduce kainate- and Nmethyl- D-aspartate-induced intracellular Ca2 + levels in neuronal culture. Eur J Pharmacol 1992 219 53-57
    • (1992) Eur J Pharmacol , vol.219 , pp. 53-57
    • Cai, Z.1    McCaslin, P.P.2
  • 61
    • 0027235344 scopus 로고
    • Tricyclic antidepressants block NMDA receptor-mediated synaptic responses and induction of long-term potentiation in rat hippocampal slices
    • DOI 10.1016/0028-3908(93)90173-Z
    • Watanabe Y, Saito H, Abe K. Tricyclic antidepressants block NMDA receptor-mediated synaptic responses and induction of long-term potentiation in rat hippocampal slices. Neuropharmacology 1993 32 479-486 (Pubitemid 23161558)
    • (1993) Neuropharmacology , vol.32 , Issue.5 , pp. 479-486
    • Watanabe, Y.1    Saito, H.2    Abe, K.3
  • 62
    • 0033808294 scopus 로고    scopus 로고
    • Effects of antidepressants on gamma-aminobutyric acid- and N-methyl-D-aspartate-induced intracellular Ca(2 +) concentration increases in primary cultured rat cortical neurons
    • Takebayashi M, Kagaya A, Inagaki M et al. Effects of antidepressants on gamma-aminobutyric acid- and N-methyl-D-aspartate-induced intracellular Ca(2 +) concentration increases in primary cultured rat cortical neurons. Neuropsychobiology 2000 42 120-126
    • (2000) Neuropsychobiology , vol.42 , pp. 120-126
    • Takebayashi, M.1    Kagaya, A.2    Inagaki, M.3
  • 64
    • 35848941499 scopus 로고    scopus 로고
    • Direct Inhibitory Effect of Fluoxetine on N-Methyl-D-Aspartate Receptors in the Central Nervous System
    • DOI 10.1016/j.biopsych.2007.04.014, PII S0006322307003642, Depression: New Perspectives on Treatment and Etiology
    • Szasz B K., Mike A, Karoly R et al. Direct inhibitory effect of fluoxetine on N-methyl-D-aspartate receptors in the central nervous system. Biol Psychiatry 2007 62 1303-1309 (Pubitemid 350060896)
    • (2007) Biological Psychiatry , vol.62 , Issue.11 , pp. 1303-1309
    • Szasz, B.K.1    Mike, A.2    Karoly, R.3    Gerevich, Z.4    Illes, P.5    Vizi, E.S.6    Kiss, J.P.7
  • 65
    • 67650082524 scopus 로고    scopus 로고
    • Inhibitory effect of antidepressants on the NMDA-evoked ([3] H)noradrenaline release from rat hippocampal slices
    • Mayer A, Szasz B K., Kiss J P. Inhibitory effect of antidepressants on the NMDA-evoked ([3] H)noradrenaline release from rat hippocampal slices. Neurochem Int 2009 55 383-388
    • (2009) Neurochem Int , vol.55 , pp. 383-388
    • Mayer, A.1    Szasz, B.K.2    Kiss, J.P.3
  • 68
    • 33947213976 scopus 로고    scopus 로고
    • The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: Relationship to clinical effects in mood disorders
    • DOI 10.1038/sj.npp.1301178, PII 1301178
    • Du J, Suzuki K, Wei Y et al. The Anticonvulsants lamotrigine, riluzole and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders. Neuropsychopharmacology 2007 32 793-802 (Pubitemid 46426179)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.4 , pp. 793-802
    • Du, J.1    Suzuki, K.2    Wei, Y.3    Wang, Y.4    Blumenthal, R.5    Chen, Z.6    Falke, C.7    Zarate Jr., C.A.8    Manji, H.K.9
  • 69
    • 0036946642 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases the membrane expression of AMPA receptors in rat hippocampus
    • DOI 10.1016/S0028-3908(02)00299-X
    • Martinez-Turrillas R, Frechilla D, De lRio J. Chronic antidepressant treatment increases the membrane expression of AMPA receptors in rat hippocampus. Neuropharmacology 2002 43 1230-1237 (Pubitemid 36090128)
    • (2002) Neuropharmacology , vol.43 , Issue.8 , pp. 1230-1237
    • Martinez-Turrillas, R.1    Frechilla, D.2    Del Rio, J.3
  • 70
    • 33645346211 scopus 로고    scopus 로고
    • Regulation of editing and expression of glutamate alpha-amino-propionic- acid [AMPA]/kainate receptors by antidepressant drugs
    • Barbon A, Popoli M, La V ia L et al. Regulation of editing and expression of glutamate alpha-amino-propionic-acid [AMPA]/kainate receptors by antidepressant drugs. Biol Psychiatry 2006 59 713-720
    • (2006) Biol Psychiatry , vol.59 , pp. 713-720
    • Barbon, A.1    Popoli, M.2    La, V.I.L.3
  • 71
    • 0042266306 scopus 로고    scopus 로고
    • Repeated administration of antidepressants decreases field potentials in rat frontal cortex
    • DOI 10.1016/S0306-4522(03)00380-4
    • Bobula B, Tokarski K, Hess G. Repeated administration of antidepressants decreases field potenzials in rat frontal cortex. Neuroscience 2003 120 765-769 (Pubitemid 36928073)
    • (2003) Neuroscience , vol.120 , Issue.3 , pp. 765-769
    • Bobula, B.1    Tokarski, K.2    Hess, G.3
  • 72
    • 65249187797 scopus 로고    scopus 로고
    • Antidepressant treatments-induced modifications of glutamatergic transmission in rat frontal cortex
    • Bobula B, Hess G. Antidepressant treatments-induced modifications of glutamatergic transmission in rat frontal cortex. Pharmacol Rep 2008 60 865-871
    • (2008) Pharmacol Rep , vol.60 , pp. 865-871
    • Bobula, B.1    Hess, G.2
  • 73
    • 0032493304 scopus 로고    scopus 로고
    • Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex
    • DOI 10.1073/pnas.95.14.8363
    • Dixon J F., Hokin L E. Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex. Proc Natl Acad Sci USA 1998 95 8363-8368 (Pubitemid 28326118)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.14 , pp. 8363-8368
    • Dixon, J.F.1    Hokin, L.E.2
  • 74
    • 77950862759 scopus 로고    scopus 로고
    • Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortex in vitro
    • Greenhill S D., Jones R S. Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortex in vitro. Neuroscience 2010 167 456-474
    • (2010) Neuroscience , vol.167 , pp. 456-474
    • Greenhill, S.D.1    Jones, R.S.2
  • 75
    • 0025157918 scopus 로고
    • Functional antagonists at the NMDA receptor complex exhibit antidepressant actions
    • DOI 10.1016/0014-2999(90)90204-J
    • Trullas R, Skolnick P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur J Pharmacol 1990 185 1-10 (Pubitemid 20254891)
    • (1990) European Journal of Pharmacology , vol.185 , Issue.1 , pp. 1-10
    • Trullas, R.1    Skolnick, P.2
  • 76
    • 33747607039 scopus 로고    scopus 로고
    • Enhancement of antidepressant-like effects but not brain-derived neurotrophic factor mRNA expression by the novel N-methyl-D-aspartate receptor antagonist neramexane in mice
    • DOI 10.1124/jpet.106.103697
    • Kos T, Legutko B, Danysz W et al. Enhancement of antidepressant-like effects but not brain-derived neurotrophic factor mRNA expression by the novel N-methyl-D-aspartate receptor antagonist neramexane in mice. J Pharmacol Exp Ther 2006 318 1128-1136 (Pubitemid 44268318)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.318 , Issue.3 , pp. 1128-1136
    • Kos, T.1    Legutko, B.2    Danysz, W.3    Samoriski, G.4    Popik, P.5
  • 77
    • 0034982471 scopus 로고    scopus 로고
    • Effect of fluvoxamine and N-methyl-D-aspartate receptor antagonists on shock-induced depression in mice
    • Chaturvedi H K., Bapna J S., Chandra D. Effect of fluvoxamine and N-methyl-Daspartate receptor antagonists on shock-induced depression in mice. Indian J Physiol Pharmacol 2001 45 199-207 (Pubitemid 32520041)
    • (2001) Indian Journal of Physiology and Pharmacology , vol.45 , Issue.2 , pp. 199-207
    • Chaturvedi, H.K.1    Bapna, J.S.2    Chandra, D.3
  • 78
    • 0036370601 scopus 로고    scopus 로고
    • Prolonged effect of an anesthetic dose of ketamine on behavioral despair
    • Yilmaz A, Schulz D, Aksoy A et al. Prolonged effect of an anesthetic dose of ketamine on behavioral despair. Pharmacol Biochem Behav 2002 71 341-344
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 341-344
    • Yilmaz, A.1    Schulz, D.2    Aksoy, A.3
  • 79
    • 38349186799 scopus 로고    scopus 로고
    • Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors
    • DOI 10.1016/j.biopsych.2007.05.028, PII S0006322307005471
    • Maeng S, Zarate Jr C A., Du J et al. Cellular mechanisms underlying the antidepressant effects of ketamine: role of &alpha-amino-3-hydroxy-5- methylisoxazole-4-propionic acid receptors. Biol Psychiatry 2008 63 349-352 (Pubitemid 351146651)
    • (2008) Biological Psychiatry , vol.63 , Issue.4 , pp. 349-352
    • Maeng, S.1    Zarate Jr., C.A.2    Du, J.3    Schloesser, R.J.4    McCammon, J.5    Chen, G.6    Manji, H.K.7
  • 80
    • 56049120097 scopus 로고    scopus 로고
    • Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels
    • Garcia L S., Comim C M., Valvassori S S. et al. Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels. Basic Clin Pharmacol Toxicol 2008 103 502-506
    • (2008) Basic Clin Pharmacol Toxicol , vol.103 , pp. 502-506
    • Garcia, L.S.1    Comim, C.M.2    Valvassori, S.S.3
  • 81
    • 38349097619 scopus 로고    scopus 로고
    • Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
    • Garcia L S., Comim C M., Valvassori S S. et al. Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus. Prog Neuropsychopharmacol Biol Psychiatry 2008 32 140-144
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , pp. 140-144
    • Garcia, L.S.1    Comim, C.M.2    Valvassori, S.S.3
  • 82
    • 67349124358 scopus 로고    scopus 로고
    • Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models
    • Erratum in: Neuroscience 2009; 162: 1438 - 1439
    • Engin E, Treit D, Dickson C T. Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models. Neuroscience 2009 161 359-369 Erratum in: Neuroscience 2009; 162: 1438 - 1439
    • (2009) Neuroscience , vol.161 , pp. 359-369
    • Engin, E.1    Treit, D.2    Dickson, C.T.3
  • 83
    • 33645977758 scopus 로고    scopus 로고
    • Effect of 5-HT3 receptor antagonist MDL 72 222 on behaviors induced by ketamine in rats and mice
    • Kos T, Popik P, Pietraszek M et al. Effect of 5-HT3 receptor antagonist MDL 72 222 on behaviors induced by ketamine in rats and mice. Eur Neuropsychopharmacol 2006 16 297-310
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 297-310
    • Kos, T.1    Popik, P.2    Pietraszek, M.3
  • 84
    • 0034023816 scopus 로고    scopus 로고
    • Synergistic effect of amantadine and imipramine in the forced swimming test
    • Maj J, Rogz Z. Synergistic effect of amantadine and imipramine in the forced swimming test. Pol J Pharmacol 2000 52 111-114 (Pubitemid 30311781)
    • (2000) Polish Journal of Pharmacology , vol.52 , Issue.2 , pp. 111-114
    • Maj, J.1    Rogoz, Z.2
  • 85
    • 31944445804 scopus 로고    scopus 로고
    • Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice
    • DOI 10.1016/j.neulet.2005.10.057, PII S0304394005012450
    • Almeida R C., Souza D G., Soletti R C. et al. Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice. Neurosci Lett 2006 395 93-97 (Pubitemid 43188871)
    • (2006) Neuroscience Letters , vol.395 , Issue.2 , pp. 93-97
    • Almeida, R.C.1    Souza, D.G.2    Soletti, R.C.3    Lopez, M.G.4    Rodrigues, A.L.S.5    Gabilan, N.H.6
  • 86
    • 0036065596 scopus 로고    scopus 로고
    • Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats
    • DOI 10.1016/S0028-3908(02)00055-2, PII S0028390802000552
    • Rogoz Z, Skuza G, Maj J et al. Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats. Neuropharmacology 2002 42 1024-1030 (Pubitemid 34790257)
    • (2002) Neuropharmacology , vol.42 , Issue.8 , pp. 1024-1030
    • Rogoz, Z.1    Skuza, G.2    Maj, J.3    Danysz, W.4
  • 87
    • 70349939242 scopus 로고    scopus 로고
    • Glial pathology in an animal model of depression: Reversal of stress-induced cellular, metabolic and behavioural deficits by the glutamate-modulating drug riluzole
    • 30 Sep [Epub ahead of print]
    • Banasr M, Chowdhury G M., Terwilliger R et al. Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioural deficits by the glutamate-modulating drug riluzole. Mol Psychiatry 30 Sep 2008 [Epub ahead of print]
    • (2008) Mol Psychiatry
    • Banasr, M.1    Chowdhury, G.M.2    Terwilliger, R.3
  • 88
    • 18844380431 scopus 로고    scopus 로고
    • A role for AMPA receptors in mood disorders
    • Alt A, Witkin J M., Bleakman D. A role for AMPA receptors in mood disorders. Curr Pharm Des 2005 11 1511-1527
    • (2005) Curr Pharm des , vol.11 , pp. 1511-1527
    • Alt, A.1    Witkin, J.M.2    Bleakman, D.3
  • 90
    • 34249098796 scopus 로고    scopus 로고
    • AMPA receptor potentiators: Application for depression and Parkinson's disease
    • DOI 10.2174/138945007780618517
    • O'Neill M J., Witkin J M. AMPA receptor potentiators: application for depression and Parkinson's disease. Curr Drug Targets 2007 8 603-620 (Pubitemid 46794920)
    • (2007) Current Drug Targets , vol.8 , Issue.5 , pp. 603-620
    • O'Neill, M.J.1    Witkin, J.M.2
  • 91
    • 51349159679 scopus 로고    scopus 로고
    • AMPA receptor subunit 1 [GluR-A] knockout mice model the glutamate hypothesis of depression
    • Chourbaji S, Vogt M A., Fumagalli F et al. AMPA receptor subunit 1 [GluR-A] knockout mice model the glutamate hypothesis of depression. FASEB J 2008 22 3129-3134
    • (2008) FASEB J , vol.22 , pp. 3129-3134
    • Chourbaji, S.1    Vogt, M.A.2    Fumagalli, F.3
  • 92
    • 33751190762 scopus 로고    scopus 로고
    • Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests
    • DOI 10.1016/j.euroneuro.2006.03.002, PII S0924977X06000496
    • Belozertseva V, Kos T, Popik P et al. Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests. Eur Neuropsychopharmacol 2007 17 172-179 (Pubitemid 44779190)
    • (2007) European Neuropsychopharmacology , vol.17 , Issue.3 , pp. 172-179
    • Belozertseva, I.V.1    Kos, T.2    Popik, P.3    Danysz, W.4    Bespalov, A.Y.5
  • 93
    • 33748999574 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice
    • DOI 10.1124/jpet.106.103143
    • Li X, Need A B., Baez M et al. Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice. J Pharmacol Exp Ther 2006 319 254-259 (Pubitemid 44455130)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.319 , Issue.1 , pp. 254-259
    • Li, X.1    Need, A.B.2    Baez, M.3    Witkin, J.M.4
  • 95
    • 49949084013 scopus 로고    scopus 로고
    • Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341 495, in animal models of anxiety and depression
    • Bespalov A Y., Gaalen M M., Sukhotina I A. et al. Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341 495, in animal models of anxiety and depression. Eur J Pharmacol 2008 592 96-102
    • (2008) Eur J Pharmacol , vol.592 , pp. 96-102
    • Bespalov, A.Y.1    Gaalen, M.M.2    Sukhotina, I.A.3
  • 96
    • 0346219343 scopus 로고    scopus 로고
    • Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats
    • Paucha A van, Tatarczyska E, Braski P et al. Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats. Neuropharmacology 2004 46 151-159
    • (2004) Neuropharmacology , vol.46 , pp. 151-159
    • Van, P.A.1    Tatarczyska, E.2    Braski, P.3
  • 97
    • 34848860791 scopus 로고    scopus 로고
    • Activation of the mGlu7 receptor elicits antidepressant-like effects in mice
    • DOI 10.1007/s00213-007-0856-2
    • Palucha A, Klak K, Branski P et al. Activation of the mGlu7 receptor elicits antidepressant-like effects in mice. Psychopharmacology 2007 194 555-562 (Pubitemid 47492987)
    • (2007) Psychopharmacology , vol.194 , Issue.4 , pp. 555-562
    • Palucha, A.1    Klak, K.2    Branski, P.3    Van Der Putten, H.4    Flor, P.J.5    Pilc, A.6
  • 98
    • 26044460006 scopus 로고    scopus 로고
    • Model organisms: The ascent of mouse: Advances in modelling human depression and anxiety
    • DOI 10.1038/nrd1825, PII N1825
    • Cryan J F., Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov 2005 4 775-790 (Pubitemid 43090498)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.9 , pp. 775-790
    • Cryan, J.F.1    Holmes, A.2
  • 99
    • 0026334826 scopus 로고
    • Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre
    • Benoit E, Escande D. Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre. Pflugers Arch 1991 419 603-609
    • (1991) Pflugers Arch , vol.419 , pp. 603-609
    • Benoit, E.1    Escande, D.2
  • 101
    • 7444247835 scopus 로고    scopus 로고
    • Riluzole augmentation for treatment-resistant depression
    • Sanacora G, Kendell S F., Fenton L et al. Riluzole augmentation for treatment-resistant depression. Am J Psychiatry 2004 161 2132
    • (2004) Am J Psychiatry , vol.161 , pp. 2132
    • Sanacora, G.1    Kendell, S.F.2    Fenton, L.3
  • 104
    • 77949625234 scopus 로고    scopus 로고
    • Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: A pilot randomized, placebo-controlled continuation trial
    • Mathew S J., Murrough J W., aan het Rot M et al. Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial. Int J Neuropsychopharmacol 2010 13 71-82
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 71-82
    • Mathew, S.J.1    Murrough, J.W.2    Aan Het Rot, M.3
  • 105
    • 34249880119 scopus 로고    scopus 로고
    • An open-label, flexible-dose study of memantine in major depressive disorder
    • DOI 10.1097/WNF.0b013e3180314ae7, PII 0000282620070500000002
    • Ferguson J M., Shingleton R N. An open-label, flexible-dose study of memantine in major depressive disorder. Clin Neuropharmacol 2007 30 136-144 (Pubitemid 46871863)
    • (2007) Clinical Neuropharmacology , vol.30 , Issue.3 , pp. 136-144
    • Ferguson, J.M.1    Shingleton, R.N.2
  • 107
    • 42249095073 scopus 로고    scopus 로고
    • Double-blind, randomized comparison of memantine and escitalopram for the treatment of major depressive disorder comorbid with alcohol dependence
    • Muhonen L H., Lönnqvist J, Juva K et al. Double-blind, randomized comparison of memantine and escitalopram for the treatment of major depressive disorder comorbid with alcohol dependence. J Clin Psychiatry 2008 69 392-399 (Pubitemid 351549391)
    • (2008) Journal of Clinical Psychiatry , vol.69 , Issue.3 , pp. 392-399
    • Muhonen, L.H.1    Lonnqvist, J.2    Juva, K.3    Alho, H.4
  • 110
    • 76349084738 scopus 로고    scopus 로고
    • Oral Administration of the NMDA Receptor Antagonist S-Ketamine as Add-On Therapy of Depression: A Case Series
    • Paslakis G, Gilles M, Meyer-Lindenberg A et al. Oral Administration of the NMDA Receptor Antagonist S-Ketamine as Add-On Therapy of Depression: A Case Series. Pharmacopsychiatry 2010 43 33-35
    • (2010) Pharmacopsychiatry , vol.43 , pp. 33-35
    • Paslakis, G.1    Gilles, M.2    Meyer-Lindenberg, A.3
  • 111
    • 58749093029 scopus 로고    scopus 로고
    • Increased anterior cingulate cortical activity in response to fearful faces: A neurophysiological biomarker that predicts rapid antidepressant response to ketamine
    • Salvadore G, Cornwell B R., Colon-Rosario V et al. Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine. Biol Psychiatry 2009 65 289-295
    • (2009) Biol Psychiatry , vol.65 , pp. 289-295
    • Salvadore, G.1    Cornwell, B.R.2    Colon-Rosario, V.3
  • 114
    • 74549122218 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist
    • 8 Sep; [Epub ahead of print]
    • Machado-Vieira R, Yuan P, Brutsche N et al. Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist. J Clin Psychiatry 8 Sep 2009; [Epub ahead of print]
    • (2009) J Clin Psychiatry
    • MacHado-Vieira, R.1    Yuan, P.2    Brutsche, N.3
  • 115
    • 57349115973 scopus 로고    scopus 로고
    • The sigma enigma: Can sigma receptors provide a novel target for disorders of mood and cognition
    • Stahl S M. The sigma enigma: can sigma receptors provide a novel target for disorders of mood and cognition? J Clin Psychiatry 2008 69 1673-1674
    • (2008) J Clin Psychiatry , vol.69 , pp. 1673-1674
    • Stahl, S.M.1
  • 116
    • 33646537447 scopus 로고    scopus 로고
    • NR2B selective NMDA antagonists: The evolution of the ifenprodil-type pharmacophore
    • Borza I, Domány G. NR2B selective NMDA antagonists: the evolution of the ifenprodil-type pharmacophore. Curr Top Med Chem 2006 6 687-695
    • (2006) Curr Top Med Chem , vol.6 , pp. 687-695
    • Borza, I.1    Domány, G.2
  • 117
    • 69749094404 scopus 로고    scopus 로고
    • Differential c-Fos induction by different NMDA receptor antagonists with antidepressant efficacy: Potenzial clinical implications
    • Inta D, Trusel M, Riva M A. et al. Differential c-Fos induction by different NMDA receptor antagonists with antidepressant efficacy: potenzial clinical implications. Int J Neuropsychopharmacol 2009 12 1133-1136
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 1133-1136
    • Inta, D.1    Trusel, M.2    Riva, M.A.3
  • 118
    • 59049098262 scopus 로고    scopus 로고
    • An innovative design to establish proof of concept of the antidepressant effects of the NR 2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder
    • Preskorn S H., Baker B, Kolluri S et al. An innovative design to establish proof of concept of the antidepressant effects of the NR 2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder. J Clin Psychopharmacol 2008 28 631-637
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 631-637
    • Preskorn, S.H.1    Baker, B.2    Kolluri, S.3
  • 119
    • 33846073198 scopus 로고    scopus 로고
    • Antidepressant-Like Effects of Ceftriaxone in Male C57BL/6J Mice
    • DOI 10.1016/j.biopsych.2006.04.037, PII S0006322306005725
    • Mineur Y S., Picciotto M R., Sanacora G. Antidepressant-like effects of ceftriaxone in male C 57BL/ 6J mice. Biol Psychiatry 2007 61 250-252 (Pubitemid 46072785)
    • (2007) Biological Psychiatry , vol.61 , Issue.2 , pp. 250-252
    • Mineur, Y.S.1    Picciotto, M.R.2    Sanacora, G.3
  • 121
    • 49749109893 scopus 로고    scopus 로고
    • N-acetyl cysteine for depressive symptoms in bipolar disorder - A double-blind randomized placebo-controlled trial
    • Berk M, Copolov D L., Dean O et al. N-acetyl cysteine for depressive symptoms in bipolar disorder - a double-blind randomized placebo-controlled trial. Biol Psychiatry 2008 64 468-475
    • (2008) Biol Psychiatry , vol.64 , pp. 468-475
    • Berk, M.1    Copolov, D.L.2    Dean, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.