Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine

European Journal of Neuroscience

Volumn 26, Issue 12, 2007, Pages 3509-3517

  Svenningsson, Per ^a,b   Bateup, Helen ^a   Qi, Hongshi ^b   Takamiya, Kogo ^c   Huganir, Richard L ^c   Spedding, Michael ^d   Roth, Bryan L ^e   McEwen, Bruce S ^a   Greengard, Paul ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d IRIS Institut de Recherches Internationales Servier   (France)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Depression; Glutamate; Mutant mice; Signal transduction

Indexed keywords

AMPA RECEPTOR; ANTIDEPRESSANT AGENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN C FOS; PROTEIN KINASE (CALCIUM,CALMODULIN) II; TIANEPTINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN REGION; CINGULATE GYRUS; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; DRUG RECEPTOR BINDING; FRONTAL CORTEX; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; OPEN FIELD BEHAVIOR; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WILD TYPE;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BEHAVIOR, ANIMAL; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DRUG ADMINISTRATION SCHEDULE; FRONTAL LOBE; HIPPOCAMPUS; IMMOBILITY RESPONSE, TONIC; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PHOSPHORYLATION; POINT MUTATION; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, AMPA; THIAZEPINES; TISSUE DISTRIBUTION;

EID: 36949027328     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05952.x     Document Type: Article

References (46)

1. Alt, A., Nisenbaum, E.S., Bleakman, D. Witkin, J.M. (2006) A role for AMPA receptors in mood disorders. Biochem. Pharmacol., 71, 1273 1288.
2. Bai, F., Bergeron, M. Nelson, D.L. (2003) Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus. Neuropharmacology, 44, 1013 1021.
3. Barria, A., Muller, D., Derkach, V., Griffith, L.C. Soderling, T.R. (1997) Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science, 276, 2042 2045.
4. Beck, C.H. (1995) Acute treatment with antidepressant drugs selectively increases the expression of c-fos in the rat brain. J. Psychiatry Neurosci., 20, 25 32.
5. Berton, O. Nestler, E.J. (2006) New approaches to antidepressant drug discovery: beyond monoamines. Nat. Rev. Neurosci., 7, 137 151.
6. Bibb, J.A., Chen, J., Taylor, J.R., Svenningsson, P., Nishi, A., Snyder, G.L., Yan, Z., Sagawa, Z.K., Ouimet, C.C., Nairn, A.C., Nestler, E.J. Greengard, P. (2001) Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature, 410, 376 380.
7. Brocco, M., Dekeyne, A., Veiga, S., Girardon, S. Millan, M.J. (2002) Induction of hyperlocomotion in mice exposed to a novel environment by inhibition of serotonin reuptake. A pharmacological characterization of diverse classes of antidepressant agents. Pharmacol. Biochem. Behav., 71, 667 680.
8. Conrad, C.D., Galea, L.A.M., Kuroda, Y. McEwen, B.S. (1996) Chronic stress impairs rat spatial memory on the Y-Maze and this effect is blocked by tianeptine pre-treatment. Behav. Neurosci., 110, 1321 1334.
9. Coyle, J.T. Duman, R.S. (2003) Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron, 38, 157 160.
10. Cryan, J.F., Mombereau, C. Vassout, A. (2005) The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci. Biobehav. Rev., 29, 571 625.
11. Du, J., Suzuki, K., Wei, Y., Wang, Y., Blumenthal, R., Chen, Z., Falke, C. Zarate, C.A. Jr. Manji, H.K. (2007) The Anticonvulsants lamotrigine, riluzole, and valproate differentially. regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders. Neuropsychopharmacology, 32, 793 802.
12. Duncan, G.E., Knapp, D.J., Johnson, K.B. Breese, G.R. (1996) Functional classification of antidepressants based on antagonism of swim stress-induced fos-like immunoreactivity. J. Pharmacol. Exp. Ther., 277, 1076 1089.
13. El Yacoubi, M., Bouali, S., Popa, D., Naudon, L., Leroux-Nicollet, I., Hamon, M., Costentin, J., Adrien, J. Vaugeois, J.M. (2003) Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression. Proc. Natl Acad. Sci. USA, 100, 6227 6232.
14. Fattaccini, C.M., Bolanos-Jimenez, F., Gozlan, H. Hamon, M. (1990) Tianeptine stimulates uptake of 5-hydroxytryptamine in vivo in the rat brain. Neuropharmacology, 29, 1 8.
15. Jeon, S.H., Seong, Y.S., Juhnn, Y.S., Kang, U.G., Ha, K.S., Kim, Y.S. Park, J.B. (1997) Electroconvulsive shock increases the phosphorylation of cyclic AMP response element binding protein at Ser-133 in rat hippocampus but not in cerebellum. Neuropharmacology, 36, 411 414.
16. Kato, G. Weitsch, A.F. (1988) Neurochemical profile of tianeptine, a new antidepressant drug. Clin. Neuropharmacol., 11, S43 S50.
17. Kole, M.H., Swan, L. Fuchs, E. (2002) The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. Eur. J. Neurosci., 16, 807 816.
18. Koshikawa, N., Kitamura, M., Tomiyama, K. Stephenson, J.D. (1998) Chronic treatment with tianeptine attenuates the behavioural effects induced by 5-HTP, but not the effects on hippocampal 5-HT concentrations. Neurosci. Res. Commun., 22, 107 116.
19. Laifenfeld, D., Karry, R., Grauer, E., Klein, E. Ben-Shachar, D. (2005) Antidepressants and prolonged stress in rats modulate CAM-L1, laminin, and pCREB, implicated in neuronal plasticity. Neurobiol. Dis., 20, 432 441.
20. Lee, H.K., Takamiya, K., Han, J.S., Man, H., Kim, C.H. Rumbaugh, G., Yu S., Ding, L., He, C., Petralia, P.S., Wenthold, R.J., Gallagher, M. Huganir, R.L. (2003) Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Cell, 112, 631 643.
21. Magarinos, A.M., Deslandes, A. McEwen, B.S. (1999) Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress. Eur. J. Pharmacol., 371, 113 122.
22. Malagie, I., Deslandes, A. Gardier, A.M. (2000) Effects of acute and chronic tianeptine administration on serotonin outflow inrats: comparison with paroxetine by using in vivo microdialysis. Eur. J Pharmacol., 403, 55 65.
23. Manji, H.K., Drevets, W.C. Charney, D.S. (2001) The cellular neurobiology of depression. Nat. Med., 7, 541 547.
24. Mayorga, A.J., Dalvi, A., Page, M.E., Zimov-Levinson, S., Hen, R. Lucki, I. (2001) Antidepressant-like behavioral effects in 5-hydroxytryptamine (1A) and 5-hydroxytryptamine (1B) receptor mutant mice. J. Pharmacol. Exp. Ther., 298, 1101 1107.
25. McEwen, B.S. Olie, J.P. (2005) Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: tianeptine. Mol. Psychiatry, 10, 525 537.
26. Menini, T., Mocaer, E. Garattini, S. (1987) Tianeptine, a selective enhancer of serotonin uptake in rat brain. Naunyn-Schmiedeberg's Arch. Pharmacol., 336, 478 482.
27. Mocaër, E., Rettori, M.C. Kamoun, A. (1988) Pharmacological antidepressive effects and tianeptine-induced 5-HT uptake increase. Clin. Neuropharmacol., 11, S32 S42.
28. Nowakowska, E., Kus, K., Chodera, A. Rybakowski, J. (2000) Behavioural effects of fluoxetine and tianeptine, two antidepressants with opposite action mechanisms, in rats. Arzneimittelforschung, 50, 5 10.
29. Popoli, M., Vocaturo, C., Perez, J., Smeraldi, E. Racagni, G. (1995) Presynaptic Ca2+/calmodulin-dependent protein kinase II: autophosphorylation and activity increase in the hippocampus after long-term blockade of serotonin reuptake. Mol. Pharmacol., 48, 623 629.
30. Rajkowska, G. (2000) Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol. Psychiatry, 48, 766 777.
31. Redolat, R., Vidal, J., Gomez, M.C. Carrasco, M.C. (2005) Effects of acute bupropion administration on locomotor activity in adolescent and adult mice. Behav. Pharmacol., 16, 59 62.
32. Roche, K.W., O'Brien, R.J., Mammen, A.L., Bernhardt, J. Huganir, R.L. (1996) Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. Neuron, 16, 1179 1188.
33. Romeo, R.D., Mueller, A., Sisti, H.M., Ogawa, S., McEwen, B.S. Brake, W.G. (2003) Anxiety and fear behaviors in adult male and female C57BL/6 mice are modulated by maternal separation. Horm. Behav., 43, 561 567.
34. Roth, B.L., Baner, K., Westkaemper, R., Siebert, D., Rice, K.C., Steinberg, S., Ernsberger, P. Rothman, R.B. (2002) Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist. Proc. Natl Acad. Sci. USA, 99, 11934 11939.
35. Sachdev, P. Aniss, A.M. (1994) Slowness of movement in melancholic depression. Biol. Psychiatry, 35, 253 262.
36. Sairanen, M., O'Leary, O.F., Knuttila, J.E. Castren, E. (2007) Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat. Neuroscience, 144, 368 374.
37. Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., Belzung, C. Hen, R. (2003) Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science, 301, 805 809.
38. Shakesby, A.C., Anwyl, R. Rowan, M.J. (2002) Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents. J. Neurosci., 22, 3638 3644.
39. Shapiro, D.A., Renock, S., Arrington, E., Chiodo, L.A., Liu, L.X., Sibley, D.R., Roth, B.L. Mailman, R. (2003) Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology. Neuropsychopharmacology, 28, 1400 1411.
40. Spedding, M., Jay, T., Costa e Silva, J. Perret, L. (2005) A pathophysiological paradigm for the therapy of psychiatric disease. Nat. Rev. Drug Discov., 4, 467 476.
41. Steru, L., Chermat, R., Thierry, B. Simon, P. (1985) The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology, 85, 367 370.
42. Svenningsson, P., Tzavara, E.T., Carruthers, R., Rachleff, I., Wattler, S., Nehls, M., McKinzie, D.L., Fienberg, A.A., Nomikos, G.G. Greengard, P. (2003) Diverse psychotomimetics act through a common signaling pathway. Science, 302, 1412 1415.
43. Svenningsson, P., Tzavara, E.T., Witkin, J.M., Fienberg, A.A., Nomikos, G.G. Greengard, P. (2002) Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac). Proc. Natl Acad. Sci. USA, 99, 3182 3187.
44. Thome, J., Sakai, N., Shin, K., Steffen, C., Zhang, Y.J., Impey, S., Storm, D. Duman, R.S. (2000) cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. J. Neurosci., 20, 4030 4036.
45. Tiraboschi, E., Tardito, D., Kasahara, J., Moraschi, S., Pruneri, P., Gennarelli, M., Racagni, G. Popoli, M. (2004) Selective phosphorylation of nuclear CREB by fluoxetine is linked to activation of CaM kinase IV and MAP kinase cascades. Neuropsychopharmacology, 29, 1831 1840.
46. Vaugeois, J.M., Corera, A.T., Deslandes, A. Costentin, J. (1999) Although chemically related to amineptine, the antidepressant tianeptine is not a dopamine uptake inhibitor. Pharmacol. Biochem. Behav., 63, 285 290.