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Volumn 19, Issue 8, 2011, Pages 2582-2588

Design, synthesis, and structure-activity relationship studies of thiophene-3-carboxamide derivatives as dual inhibitors of the c-Jun N-terminal kinase

(10) De, Surya K a Barile, Elisa a Chen, Vida a Stebbins, John L a Cellitti, Jason F a MacHleidt, Thomas b Carlson, Coby B b Yang, Li a Dahl, Russell a Pellecchia, Maurizio a

a BURNHAM INSTITUTE (United States)

b INVITROGEN CORPORATION (United States)

Author keywords

JIP1; JNK; Kinase inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATE; BI 78D 3; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; THIOPHENE 3 CARBOXAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CELL LINE; DRUG DESIGN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR MIMICRY; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 79954420335 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2011.03.017 Document Type: Article

Times cited : (14)

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