Binding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms

Journal of Molecular Recognition

Volumn 24, Issue 4, 2011, Pages 585-596

  McDonald, Caleb B ^a   Seldeen, Kenneth L ^a   Deegan, Brian J ^a   Bhat, Vikas ^a   Farooq, Amjad ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Gab1 docker; Grb2 adaptor; isothermal titration calorimetry; macromolecular modeling; SH3 ligand thermodynamics

Indexed keywords

GAB1 PROTEIN, HUMAN; GRB2 PROTEIN, HUMAN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEOME; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CALORIMETRY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CALORIMETRY; GRB2 ADAPTOR PROTEIN; HUMANS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEOME; THERMODYNAMICS;

EID: 79953795944     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.1080     Document Type: Article

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