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Oncogene

Volumn 19, Issue 54, 2000, Pages 6271-6276

Grb2 downregulation leads to Akt inactivation in heregulin-stimulated and ErbB2-overexpressing breast cancer cells

(5) Lim, Soo Jeong a Lopez Berestein, Gabriel a Hung, Mien Chie b Lupu, Ruth c Tari, Ana M a

a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER (United States)

b UNIVERSITY OF TEXAS (United States)

c UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Akt; Breast cancer; ErbB2; Grb2; Heregulin

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOGENESIS; ONCOGENE NEU; PRIORITY JOURNAL; TRANSACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CELL DIVISION; DOWN-REGULATION; FEMALE; GRB2 ADAPTOR PROTEIN; HUMANS; LIPOSOMES; NEUREGULIN-1; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ERBB-2; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034649505 PISSN: 09509232 EISSN: None Source Type: Journal
DOI: 10.1038/sj.onc.1204014 Document Type: Article

Times cited : (40)

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