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Volumn 461, Issue 3, 2011, Pages 307-315

Invited review: Decoding the microRNA response to hypoxia

Author keywords

Angiogenesis; DNA repair; Hypoxia; Metabolism; MicroRNA; Stress

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA; MICRORNA 107; MICRORNA 21; PROTEIN P53; RAD52 PROTEIN; RNA POLYMERASE II; SCATTER FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79953748872     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0910-5     Document Type: Review
Times cited : (68)

References (82)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs. Genomics, biogenesis, mechanism, and function
    • Bartel DP (2004) MicroRNAs. Genomics, biogenesis, mechanism, and function. Cell 116:281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215-233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 0034616963 scopus 로고    scopus 로고
    • Stable binding ofhuman XPC complex to irradiated DNA confers strong discrimination for damaged sites
    • Batty D, Rapic'-Otrin V, Levine AS, Wood RD (2000) Stable binding ofhuman XPC complex to irradiated DNA confers strong discrimination for damaged sites. J Mol Biol 300:275-290
    • (2000) J Mol Biol , vol.300 , pp. 275-290
    • Batty, D.1    Rapic'-Otrin, V.2    Levine, A.S.3    Wood, R.D.4
  • 4
    • 57149142495 scopus 로고    scopus 로고
    • The impact of O2 availability on human cancer
    • Bertout JA, Patel SA, Simon MC (2008) The impact of O2 availability on human cancer. Nat Rev Cancer 8:967-975
    • (2008) Nat Rev Cancer , vol.8 , pp. 967-975
    • Bertout, J.A.1    Patel, S.A.2    Simon, M.C.3
  • 6
    • 0037418839 scopus 로고    scopus 로고
    • Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • DOI 10.1016/S0092-8674(03)00231-9
    • Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM (2003) Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113:25-36 (Pubitemid 36411957)
    • (2003) Cell , vol.113 , Issue.1 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 7
    • 58849093262 scopus 로고    scopus 로고
    • Revisiting the principles of microRNA target recognition and mode of action
    • Brodersen P, Voinnet O (2009) Revisiting the principles of microRNA target recognition and mode of action. Nat Rev Mol Cell Biol 10:141-148
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 141-148
    • Brodersen, P.1    Voinnet, O.2
  • 10
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • DOI 10.1038/74651
    • Carmeliet P (2000) Mechanisms of angiogenesis and arteriogenesis.Nat Med 6:389-395 (Pubitemid 30208155)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 389-395
    • Carmeliet, P.1
  • 14
    • 70349478990 scopus 로고    scopus 로고
    • MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
    • Chan SY, Zhang YY, Hemann C, Mahoney CE, Zweier JL, Loscalzo J (2009) MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab 10:273-284
    • (2009) Cell Metab , vol.10 , pp. 273-284
    • Chan, S.Y.1    Zhang, Y.Y.2    Hemann, C.3    Mahoney, C.E.4    Zweier, J.L.5    Loscalzo, J.6
  • 15
    • 77955170881 scopus 로고    scopus 로고
    • Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression
    • Chen Z, Li Y, Zhang H, Huang P, Luthra R (2010) Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene 29:4362-4368
    • (2010) Oncogene , vol.29 , pp. 4362-4368
    • Chen, Z.1    Li, Y.2    Zhang, H.3    Huang, P.4    Luthra, R.5
  • 17
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi SW, Zang JB, Mele A, Darnell RB (2009) Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460:479-486
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 19
    • 59149091637 scopus 로고    scopus 로고
    • Micro-RNA regulation of DNA repair gene expression in hypoxic stress
    • Crosby ME, Kulshreshtha R, Ivan M, Glazer PM (2009) Micro-RNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res 69:1221-1229
    • (2009) Cancer Res , vol.69 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 20
    • 0842328798 scopus 로고    scopus 로고
    • Roles of Mitochondria in Health and Disease
    • Duchen MR (2004) Roles of mitochondria in health and disease. Diabetes 53(Suppl 1):S96-S102 (Pubitemid 38168700)
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Duchen, M.R.1
  • 23
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • DOI 10.1038/nrc909
    • Ferrara N (2002) VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2:795-803 (Pubitemid 37328914)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.10 , pp. 795-803
    • Ferrara, N.1
  • 25
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285:1182-1186
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 27
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • Gibbings DJ, Ciaudo C, Erhardt M, Voinnet O (2009) Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol 11:1143-1149
    • (2009) Nat Cell Biol , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 29
    • 27344456287 scopus 로고    scopus 로고
    • MicroRNA target predictions across seven Drosophila species and comparison to mammalian targets
    • Grun D, Wang YL, Langenberger D, Gunsalus KC, Rajewsky N (2005) microRNA target predictions across seven Drosophila species and comparison to mammalian targets. PLoS Comput Biol 1:e13
    • (2005) PLoS Comput Biol , vol.1
    • Grun, D.1    Wang, Y.L.2    Langenberger, D.3    Gunsalus, K.C.4    Rajewsky, N.5
  • 30
    • 33846941188 scopus 로고    scopus 로고
    • High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma
    • Hebert C, Norris K, Scheper MA, Nikitakis N, Sauk JJ (2007) High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma. Mol Cancer 6:5
    • (2007) Mol Cancer , vol.6 , pp. 5
    • Hebert, C.1    Norris, K.2    Scheper, M.A.3    Nikitakis, N.4    Sauk, J.J.5
  • 33
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA
    • DOI 10.1126/science.1062961
    • Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD (2001) A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293:834-838 (Pubitemid 32743968)
    • (2001) Science , vol.293 , Issue.5531 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 35
    • 0347357618 scopus 로고    scopus 로고
    • A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
    • DOI 10.1038/nature02255
    • Johnston RJ, Hobert O (2003) A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 426:845-849 (Pubitemid 38056870)
    • (2003) Nature , vol.426 , Issue.6968 , pp. 845-849
    • Johnston Jr., R.J.1    Hobert, O.2
  • 37
    • 0344874751 scopus 로고    scopus 로고
    • Cell Type-Specific Regulation of Angiogenic Growth Factor Gene Expression and Induction of Angiogenesis in Nonischemic Tissue by a Constitutively Active Form of Hypoxia-Inducible Factor 1
    • DOI 10.1161/01.RES.0000102937.50486.1B
    • Kelly BD, Hackett SF, Hirota K, Oshima Y, Cai Z, Berg-Dixon S, Rowan A, Yan Z, Campochiaro PA, Semenza GL (2003) Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ Res 93:1074-1081 (Pubitemid 37485038)
    • (2003) Circulation Research , vol.93 , Issue.11 , pp. 1074-1081
    • Kelly, B.D.1    Hackett, S.F.2    Hirota, K.3    Oshima, Y.4    Cai, Z.5    Berg-Dixon, S.6    Rowan, A.7    Yan, Z.8    Campochiaro, P.A.9    Semenza, G.L.10
  • 38
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • DOI 10.1056/NEJMra0706596
    • Kerbel RS (2008) Tumor angiogenesis. N Engl J Med 358:2039-2049 (Pubitemid 351656458)
    • (2008) New England Journal of Medicine , vol.358 , Issue.19 , pp. 2039-2049
    • Kerbel, R.S.1
  • 39
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • DOI 10.1016/S0092-8674(03)00801-8
    • Khvorova A, Reynolds A, Jayasena SD (2003) Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-216 (Pubitemid 37329584)
    • (2003) Cell , vol.115 , Issue.2 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 40
    • 34250017082 scopus 로고    scopus 로고
    • 7G Cap Binding-like Motif within Human Ago2 Represses Translation
    • DOI 10.1016/j.cell.2007.05.016, PII S0092867407006538
    • Kiriakidou M, Tan GS, Lamprinaki S, De Planell-Saguer M, Nelson PT, Mourelatos Z (2007) An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell 129:1141-1151 (Pubitemid 46891041)
    • (2007) Cell , vol.129 , Issue.6 , pp. 1141-1151
    • Kiriakidou, M.1    Tan, G.S.2    Lamprinaki, S.3    De Planell-Saguer, M.4    Nelson, P.T.5    Mourelatos, Z.6
  • 41
    • 77957091969 scopus 로고    scopus 로고
    • Circulating microRNA in body fluid: A new potential biomarker for cancer diagnosis and prognosis
    • Kosaka N, Iguchi H, Ochiya T (2010) Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis. Cancer Sci 101:2087-2092
    • (2010) Cancer Sci , vol.101 , pp. 2087-2092
    • Kosaka, N.1    Iguchi, H.2    Ochiya, T.3
  • 42
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J, Loedige I, Filipowicz W (2010) The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11:597-610
    • (2010) Nat Rev Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 44
    • 40949122258 scopus 로고    scopus 로고
    • A microRNA component of the hypoxic response
    • DOI 10.1038/sj.cdd.4402310, PII 4402310, The biology of Hypoxia-inducible factors
    • Kulshreshtha R, Davuluri RV, Calin GA, Ivan M (2008) A microRNA component of the hypoxic response. Cell Death Differ 15:667-671 (Pubitemid 351405070)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 667-671
    • Kulshreshtha, R.1    Davuluri, R.V.2    Calin, G.A.3    Ivan, M.4
  • 45
    • 21244448730 scopus 로고    scopus 로고
    • Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development
    • DOI 10.1016/j.cell.2005.04.016, PII S009286740500396X
    • Leaman D, Chen PY, Fak J, Yalcin A, Pearce M, Unnerstall U, Marks DS, Sander C, Tuschl T, Gaul U (2005) Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell 121:1097-1108 (Pubitemid 40884399)
    • (2005) Cell , vol.121 , Issue.7 , pp. 1097-1108
    • Leaman, D.1    Po, Y.C.2    Fak, J.3    Yalcin, A.4    Pearce, M.5    Unnerstall, U.6    Marks, D.S.7    Sander, C.8    Tuschl, T.9    Gaul, U.10
  • 46
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • DOI 10.1016/0092-8674(93)90529-Y
    • Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854 (Pubitemid 24014542)
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 47
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • DOI 10.1093/emboj/cdf476
    • Lee Y, Jeon K, Lee JT, Kim S, Kim VN (2002) MicroRNA maturation: stepwise processing and subcellular localization. EMBO J 21:4663-4670 (Pubitemid 34984353)
    • (2002) EMBO Journal , vol.21 , Issue.17 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.-T.3    Kim, S.4    Kim, V.N.5
  • 49
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • DOI 10.1038/sj.emboj.7600385
    • Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, Kim VN (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23:4051-4060 (Pubitemid 39472426)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.-H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 51
    • 64249144494 scopus 로고    scopus 로고
    • A microRNA imparts robustness against environmental fluctuation during development
    • Li X, Cassidy JJ, Reinke CA, Fischboeck S, Carthew RW (2009) A microRNA imparts robustness against environmental fluctuation during development. Cell 137:273-282
    • (2009) Cell , vol.137 , pp. 273-282
    • Li, X.1    Cassidy, J.J.2    Reinke, C.A.3    Fischboeck, S.4    Carthew, R.W.5
  • 52
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • DOI 10.1126/science.1137999
    • Mayr C, Hemann MT, Bartel DP (2007) Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315:1576-1579 (Pubitemid 46449474)
    • (2007) Science , vol.315 , Issue.5818 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 53
    • 77956339881 scopus 로고    scopus 로고
    • OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
    • Medina PP, Nolde M, Slack FJ (2010) OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 467:86-90
    • (2010) Nature , vol.467 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 55
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • DOI 10.1038/sj.cdd.4401183
    • Oren M (2003) Decision making by p53: life, death and cancer. Cell Death Differ 10:431-442 (Pubitemid 36626355)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.4 , pp. 431-442
    • Oren, M.1
  • 57
    • 48149113439 scopus 로고    scopus 로고
    • Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans
    • Pocock R, Hobert O (2008) Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans. Nat Neurosci 11:894-900
    • (2008) Nat Neurosci , vol.11 , pp. 894-900
    • Pocock, R.1    Hobert, O.2
  • 58
    • 77951667748 scopus 로고    scopus 로고
    • Hypoxia activates a latent circuit for processing gustatory information in C. elegans
    • Pocock R, Hobert O (2010) Hypoxia activates a latent circuit for processing gustatory information in C. elegans. Nat Neurosci 13:610-614
    • (2010) Nat Neurosci , vol.13 , pp. 610-614
    • Pocock, R.1    Hobert, O.2
  • 59
    • 0034533143 scopus 로고    scopus 로고
    • Targeting tumors through the HIF system
    • DOI 10.1038/82113
    • Ratcliffe PJ, Pugh CW, Maxwell PH (2000) Targeting tumors through the HIF system. Nat Med 6:1315-1316 (Pubitemid 32001002)
    • (2000) Nature Medicine , vol.6 , Issue.12 , pp. 1315-1316
    • Ratcliffe, P.J.1    Pugh, C.W.2    Maxwell, P.H.3
  • 61
    • 0029753768 scopus 로고    scopus 로고
    • Genetic instability induced by the tumor microenvironment
    • Reynolds TY, Rockwell S, Glazer PM (1996) Genetic instability induced by the tumor microenvironment. Cancer Res 56:5754-5757 (Pubitemid 26422184)
    • (1996) Cancer Research , vol.56 , Issue.24 , pp. 5754-5757
    • Reynolds, T.Y.1    Rockwell, S.2    Glazer, P.M.3
  • 62
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • DOI 10.1038/nature05983, PII NATURE05983
    • Ruby JG, Jan CH, Bartel DP (2007) Intronic microRNA precursors that bypass Drosha processing. Nature 448:83-86 (Pubitemid 47037009)
    • (2007) Nature , vol.448 , Issue.7149 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 63
    • 50649100744 scopus 로고    scopus 로고
    • Mechanism of eukaryotic homologous recombination
    • San Filippo J, Sung P, Klein H (2008) Mechanism of eukaryotic homologous recombination. Annu Rev Biochem 77:229-257
    • (2008) Annu Rev Biochem , vol.77 , pp. 229-257
    • San Filippo, J.1    Sung, P.2    Klein, H.3
  • 64
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • DOI 10.1016/S0092-8674(03)00759-1
    • Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208 (Pubitemid 37329583)
    • (2003) Cell , vol.115 , Issue.2 , pp. 199-208
    • Schwarz, D.S.1    Hutvagner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 66
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • DOI 10.1016/S1471-4914(01)02090-1
    • Semenza GL (2001) Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol Med 7:345-350 (Pubitemid 32735019)
    • (2001) Trends in Molecular Medicine , vol.7 , Issue.8 , pp. 345-350
    • Semenza, G.L.1
  • 67
    • 34347227058 scopus 로고    scopus 로고
    • Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
    • DOI 10.1042/BJ20070389
    • Semenza GL (2007) Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Biochem J 405:1-9 (Pubitemid 46999919)
    • (2007) Biochemical Journal , vol.405 , Issue.1 , pp. 1-9
    • Semenza, G.L.1
  • 68
    • 0030460724 scopus 로고    scopus 로고
    • Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
    • Semenza GL, Jiang BH, Leung SW, Passantino R, Concordet JP, Maire P, Giallongo A (1996) Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 271:32529-32537
    • (1996) J Biol Chem , vol.271 , pp. 32529-32537
    • Semenza, G.L.1    Jiang, B.H.2    Leung, S.W.3    Passantino, R.4    Concordet, J.P.5    Maire, P.6    Giallongo, A.7
  • 69
    • 54049146968 scopus 로고    scopus 로고
    • The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1
    • Simon MP, Tournaire R, Pouyssegur J (2008) The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1. J Cell Physiol 217:809-818
    • (2008) J Cell Physiol , vol.217 , pp. 809-818
    • Simon, M.P.1    Tournaire, R.2    Pouyssegur, J.3
  • 70
    • 0036175596 scopus 로고    scopus 로고
    • Mitochondrial contributions to tissue damage in stroke
    • DOI 10.1016/S0197-0186(01)00122-X, PII S019701860100122X
    • Sims NR, Anderson MF (2002) Mitochondrial contributions to tissue damage in stroke. Neurochem Int 40:511-526 (Pubitemid 34159152)
    • (2002) Neurochemistry International , vol.40 , Issue.6 , pp. 511-526
    • Sims, N.R.1    Anderson, M.F.2
  • 71
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
    • Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G (2000) The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 5:659-669
    • (2000) Mol Cell , vol.5 , pp. 659-669
    • Slack, F.J.1    Basson, M.2    Liu, Z.3    Ambros, V.4    Horvitz, H.R.5    Ruvkun, G.6
  • 72
    • 33747619857 scopus 로고    scopus 로고
    • P53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase
    • DOI 10.1126/science.1126391
    • Teodoro JG, Parker AE, Zhu X, Green MR (2006) p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase. Science 313:968-971 (Pubitemid 44267388)
    • (2006) Science , vol.313 , Issue.5789 , pp. 968-971
    • Teodoro, J.G.1    Parker, A.E.2    Zhu, X.3    Green, M.R.4
  • 73
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: A platform for investigating biology
    • Then C. elegans Sequencing Consortium
    • Then C. elegans Sequencing Consortium (1998) Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282:2012-2018
    • (1998) Science , vol.282 , pp. 2012-2018
  • 74
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • Vogelstein B, Kinzler KW (2004) Cancer genes and the pathways they control. Nat Med 10:789-799 (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 75
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92:5510-5514
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 76
    • 68749095252 scopus 로고    scopus 로고
    • MiR156-regulated SPL transcription factors define an endogenous flowering pathway in Arabidopsis thaliana
    • Wang JW, Czech B, Weigel D (2009) miR156-regulated SPL transcription factors define an endogenous flowering pathway in Arabidopsis thaliana. Cell 138:738-749
    • (2009) Cell , vol.138 , pp. 738-749
    • Wang, J.W.1    Czech, B.2    Weigel, D.3
  • 77
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • DOI 10.1038/sj.onc.1210293, PII 1210293
    • Welch C, Chen Y, Stallings RL (2007) MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 26:5017-5022 (Pubitemid 47172643)
    • (2007) Oncogene , vol.26 , Issue.34 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stallings, R.L.3
  • 78
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • DOI 10.1016/0092-8674(93)90530-4
    • Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-862 (Pubitemid 24014543)
    • (1993) Cell , vol.75 , Issue.5 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 80
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • DOI 10.1101/gad.1158803
    • Yi R, Qin Y, Macara IG, Cullen BR (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17:3011-3016 (Pubitemid 38040764)
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 81
    • 0037154738 scopus 로고    scopus 로고
    • Effect of p53 status on tumor response to antiangiogenic therapy
    • DOI 10.1126/science.1068327
    • Yu JL, Rak JW, Coomber BL, Hicklin DJ, Kerbel RS (2002) Effect of p53 status on tumor response to antiangiogenic therapy. Science 295:1526-1528 (Pubitemid 34174008)
    • (2002) Science , vol.295 , Issue.5559 , pp. 1526-1528
    • Yu, J.L.1    Rak, J.W.2    Coomber, B.L.3    Hicklin, D.J.4    Kerbel, R.S.5
  • 82
    • 36249012075 scopus 로고    scopus 로고
    • Systematic Identification of C. elegans miRISC Proteins, miRNAs, and mRNA Targets by Their Interactions with GW182 Proteins AIN-1 and AIN-2
    • DOI 10.1016/j.molcel.2007.09.014, PII S1097276507006260
    • Zhang L, Ding L, Cheung TH, Dong MQ, Chen J, Sewell AK, Liu X, Yates JR 3rd, Han M (2007) Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell 28:598-613 (Pubitemid 350137791)
    • (2007) Molecular Cell , vol.28 , Issue.4 , pp. 598-613
    • Zhang, L.1    Ding, L.2    Cheung, T.H.3    Dong, M.-Q.4    Chen, J.5    Sewell, A.K.6    Liu, X.7    Yates III, J.R.8    Han, M.9


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