MYST-family histone acetyltransferases: Beyond chromatin

Cellular and Molecular Life Sciences

Volumn 68, Issue 7, 2011, Pages 1147-1156

  Sapountzi, Vasileia ^a   Côté, Jacques ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Acetyltransferases; HBO1; Histones; Lysines; MOF; MYST; NuA4; TIP60

Indexed keywords

ESSENTIAL SAS2 RELATED ACETYLTRANSFERASE 1; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE BINDING TO ORC1; MALES ABSENT ON THE FIRST PROTEIN; MONOCYTIC LEUKEMIA ZINC FINGER PROTEIN; TAT INTERACTING PROTEIN 60; UNCLASSIFIED DRUG;

CELL CYCLE; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; COMPLEX FORMATION; DNA REPAIR; ENZYME SUBSTRATE; GENE MUTATION; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; HETEROCHROMATIN; HISTONE ACETYLATION; HUMAN; NONHUMAN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; RNA PROCESSING; SIGNAL TRANSDUCTION;

ACETYLATION; CHROMATIN; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; ISOENZYMES; LYSINE;

EID: 79953712902     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0599-9     Document Type: Review

References (97)

1. CD Allis SL Berger J Cote S Dent T Jenuwien T Kouzarides L Pillus D Reinberg Y Shi R Shiekhattar A Shilatifard J Workman Y Zhang 2007 New nomenclature for chromatin-modifying enzymes Cell 131 633 636 18022353 10.1016/j.cell.2007.10.039 1:CAS:528:DC%2BD2sXhsVSgur%2FI (Pubitemid 350089969)
2. KT Smith JL Workman 2009 Introducing the acetylome Nat Biotechnol 27 917 919 19816449 10.1038/nbt1009-917 1:CAS:528:DC%2BD1MXht1CisLnP
3. C Choudhary C Kumar F Gnad ML Nielsen M Rehman TC Walther JV Olsen M Mann 2009 Lysine acetylation targets protein complexes and co-regulates major cellular functions Science 325 834 840 19608861 10.1126/science.1175371 1:CAS:528:DC%2BD1MXps1Ogt70%3D
4. H Iwabata M Yoshida Y Komatsu 2005 Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies Proteomics 5 4653 4664 16247734 10.1002/pmic.200500042 1:CAS:528:DC%2BD28Xktlegtg%3D%3D (Pubitemid 43016886)
5. SC Kim R Sprung Y Chen Y Xu H Ball J Pei T Cheng Y Kho H Xiao L Xiao NV Grishin M White XJ Yang Y Zhao 2006 Substrate and functional diversity of lysine acetylation revealed by a proteomics survey Mol Cell 23 607 618 16916647 10.1016/j.molcel.2006.06.026 1:CAS:528:DC%2BD28Xpt1Snurk%3D (Pubitemid 44205490)
6. BJ Yu JA Kim JH Moon SE Ryu JG Pan 2008 The diversity of lysine-acetylated proteins in Escherichia coli J Microbiol Biotechnol 18 1529 1536 18852508 1:CAS:528:DC%2BD1MXotFSktrk%3D
7. S Zhao W Xu W Jiang W Yu Y Lin T Zhang J Yao L Zhou Y Zeng H Li Y Li J Shi W An SM Hancock F He L Qin J Chin P Yang X Chen Q Lei Y Xiong KL Guan 2010 Regulation of cellular metabolism by protein lysine acetylation Science 327 1000 1004 20167786 10.1126/science.1179689 1:CAS:528:DC%2BC3cXitVSjtbo%3D
8. SD Taverna H Li AJ Ruthenburg CD Allis DJ Patel 2007 How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers Nat Struct Mol Biol 14 1025 1040 17984965 10.1038/nsmb1338 1:CAS:528:DC%2BD2sXht1Kjs7vE (Pubitemid 350060344)
9. JA Latham SY Dent 2007 Cross-regulation of histone modifications Nat Struct Mol Biol 14 1017 1024 17984964 10.1038/nsmb1307 1:CAS:528: DC%2BD2sXht1Kjs7jF (Pubitemid 350060331)
10. VG Allfrey R Faulkner AE Mirsky 1964 Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis Proc Natl Acad Sci USA 51 786 794 14172992 10.1073/pnas.51.5.786 1:CAS:528: DyaF2cXktlekurg%3D
11. D Ivanov A Schleiffer F Eisenhaber K Mechtler CH Haering K Nasmyth 2002 Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion Curr Biol 12 323 328 11864574 10.1016/S0960-9822(02)00681-4 1:CAS:528:DC%2BD38XhslWgtLw%3D (Pubitemid 34161478)
12. MJ Carrozza RT Utley JL Workman J Cote 2003 The diverse functions of histone acetyltransferase complexes Trends Genet 19 321 329 12801725 10.1016/S0168-9525(03)00115-X 1:CAS:528:DC%2BD3sXksVyqtbo%3D (Pubitemid 36694615)
13. KK Lee JL Workman 2007 Histone acetyltransferase complexes: one size doesn't fit all Nat Rev Mol Cell Biol 8 284 295 17380162 10.1038/nrm2145 1:CAS:528:DC%2BD2sXjtlygsrw%3D (Pubitemid 46474661)
14. MD Shahbazian M Grunstein 2007 Functions of site-specific histone acetylation and deacetylation Annu Rev Biochem 76 75 100 17362198 10.1146/annurev.biochem.76.052705.162114 1:CAS:528:DC%2BD2sXhtVehtb7O
15. N Avvakumov J Cote 2007 The MYST family of histone acetyltransferases and their intimate links to cancer Oncogene 26 5395 5407 17694081 10.1038/sj.onc.1210608 1:CAS:528:DC%2BD2sXovFeku7g%3D (Pubitemid 47255922)
16. T Thomas AK Voss 2007 The diverse biological roles of MYST histone acetyltransferase family proteins Cell Cycle 6 696 704 17374998 10.4161/cc.6.6.4013 1:CAS:528:DC%2BD2sXnvFCltb4%3D (Pubitemid 46535682)
17. RT Utley J Cote 2003 The MYST family of histone acetyltransferases Curr Top Microbiol Immunol 274 203 236 12596909 1:CAS:528:DC%2BD3sXitVCluro%3D (Pubitemid 36118993)
18. XJ Yang 2004 The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases Nucleic Acids Res 32 959 976 14960713 10.1093/nar/gkh252 1:CAS:528:DC%2BD2cXhslWktLs%3D (Pubitemid 38864676)
19. N Saksouk N Avvakumov J Cote 2008 (de) MYSTification and INGenuity of tumor suppressors Cell Mol Life Sci 65 1013 1018 18239855 10.1007/s00018-008- 7459-x 1:CAS:528:DC%2BD1cXkvFynsLk%3D
20. AK Voss T Thomas 2009 MYST family histone acetyltransferases take center stage in stem cells and development Bioessays 31 1050 1061 19722182 10.1002/bies.200900051 1:CAS:528:DC%2BD1MXhtlynsL7J
21. M Squatrito C Gorrini B Amati 2006 Tip60 in DNA damage response and growth control: many tricks in one HAT Trends Cell Biol 16 433 442 16904321 10.1016/j.tcb.2006.07.007 1:CAS:528:DC%2BD28XptFChsb0%3D (Pubitemid 44293403)
22. YY Lin JY Lu J Zhang W Walter W Dang J Wan SC Tao J Qian Y Zhao JD Boeke SL Berger H Zhu 2009 Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis Cell 136 1073 1084 19303850 10.1016/j.cell.2009.01.033 1:CAS:528:DC%2BD1MXltFSntrc%3D
23. XJ Yang M Ullah 2007 MOZ and MORF, two large MYSTic HATs in normal and cancer stem cells Oncogene 26 5408 5419 17694082 10.1038/sj.onc.1210609 1:CAS:528:DC%2BD2sXovFeku7k%3D (Pubitemid 47255923)
24. T Katsumoto Y Aikawa A Iwama S Ueda H Ichikawa T Ochiya I Kitabayashi 2006 MOZ is essential for maintenance of hematopoietic stem cells Genes Dev 20 1321 1330 16702405 10.1101/gad.1393106 1:CAS:528:DC%2BD28XltVyrtbY%3D (Pubitemid 43727592)
25. T Thomas LM Corcoran R Gugasyan MP Dixon T Brodnicki SL Nutt D Metcalf AK Voss 2006 Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells Genes Dev 20 1175 1186 16651658 10.1101/gad.1382606 1:CAS:528:DC%2BD28XkslCjsbc%3D
26. AK Voss C Collin MP Dixon T Thomas 2009 Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity Dev Cell 17 674 686 19922872 10.1016/j.devcel.2009.10.006 1:CAS:528:DC%2BD1MXhsFKltb7M
27. SD Taverna S Ilin RS Rogers JC Tanny H Lavender H Li L Baker J Boyle LP Blair BT Chait DJ Patel JD Aitchison AJ Tackett CD Allis 2006 Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs Mol Cell 24 785 796 17157260 10.1016/j.molcel.2006.10.026 1:CAS:528:DC%2BD28XhtlCns7zF (Pubitemid 44839214)
28. L Howe D Auston P Grant S John RG Cook JL Workman L Pillus 2001 Histone H3 specific acetyltransferases are essential for cell cycle progression Genes Dev 15 3144 3154 11731478 10.1101/gad.931401 1:CAS:528:DC%2BD3MXptVKmsL4%3D (Pubitemid 33115678)
29. I Kitabayashi Y Aikawa LA Nguyen A Yokoyama M Ohki 2001 Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein EMBO J 20 7184 7196 11742995 10.1093/emboj/20.24.7184 1:CAS:528:DC%2BD38XpsFym (Pubitemid 34062310)
30. N Saksouk N Avvakumov KS Champagne T Hung Y Doyon C Cayrou E Paquet M Ullah AJ Landry V Cote XJ Yang O Gozani TG Kutateladze J Cote 2009 HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail Mol Cell 33 257 265 19187766 10.1016/j.molcel.2009.01.007 1:CAS:528:DC%2BD1MXhvVyltr0%3D
31. B Miotto K Struhl 2006 Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains Mol Cell Biol 26 5969 5982 16880509 10.1128/MCB.00696-06 1:CAS:528: DC%2BD28Xot1yltrw%3D (Pubitemid 44204517)
32. B Miotto K Struhl 2008 HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1 Genes Dev 22 2633 2638 18832067 10.1101/gad.1674108 1:CAS:528:DC%2BD1cXht1ClsbvM
33. B Miotto K Struhl 2010 HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin Mol Cell 37 57 66 20129055 10.1016/j.molcel.2009.12.012 1:CAS:528:DC%2BC3cXkvFKgsLY%3D
34. Y Doyon C Cayrou M Ullah AJ Landry V Cote W Selleck WS Lane S Tan XJ Yang J Cote 2006 ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation Mol Cell 21 51 64 16387653 10.1016/j.molcel.2005.12.007 1:CAS:528:DC%2BD28Xptlelsw%3D%3D (Pubitemid 43017848)
35. M Iizuka T Matsui H Takisawa MM Smith 2006 Regulation of replication licensing by acetyltransferase Hbo1 Mol Cell Biol 26 1098 1108 16428461 10.1128/MCB.26.3.1098-1108.2006 1:CAS:528:DC%2BD28XhtVOns7s%3D (Pubitemid 43146501)
36. M Taipale S Rea K Richter A Vilar P Lichter A Imhof A Akhtar 2005 hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells Mol Cell Biol 25 6798 6810 16024812 10.1128/MCB.25.15.6798-6810. 2005 1:CAS:528:DC%2BD2MXntVSgs7w%3D (Pubitemid 41023250)
37. ER Smith C Cayrou R Huang WS Lane J Cote JC Lucchesi 2005 A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16 Mol Cell Biol 25 9175 9188 16227571 10.1128/MCB.25.21.9175-9188.2005 1:CAS:528:DC%2BD2MXhtFOnsrjK (Pubitemid 41507821)
38. A Kimura T Umehara M Horikoshi 2002 Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing Nat Genet 32 370 377 12410229 10.1038/ng993 (Pubitemid 35266110)
39. N Suka K Luo M Grunstein 2002 Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin Nat Genet 32 378 383 12379856 10.1038/ng1017 1:CAS:528:DC%2BD38Xot1Kls7k%3D (Pubitemid 35266111)
40. A Gupta GG Sharma CS Young M Agarwal ER Smith TT Paull JC Lucchesi KK Khanna T Ludwig TK Pandita 2005 Involvement of human MOF in ATM function Mol Cell Biol 25 5292 5305 15923642 10.1128/MCB.25.12.5292-5305.2005 1:CAS:528:DC%2BD2MXlt1Oru7k%3D (Pubitemid 40781125)
41. X Li L Wu CA Corsa S Kunkel Y Dou 2009 Two mammalian MOF complexes regulate transcription activation by distinct mechanisms Mol Cell 36 290 301 19854137 10.1016/j.molcel.2009.07.031 1:CAS:528:DC%2BD1MXhsFWht7vI
42. GG Sharma So Sairie A Gupta R Kumar C Cayrou N Avvakumov U Bhadra RK Pandita MH Porteus DJ Chen J Cote TK Pandita 2010 MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and DSB repair Mol Cell Biol 30 3582 3595 20479123 10.1128/MCB.01476-09 1:CAS:528:DC%2BC3cXpvVOqsb0%3D
43. S Rea G Xouri A Akhtar 2007 Males absent on the first (MOF): from flies to humans Oncogene 26 5385 5394 17694080 10.1038/sj.onc.1210607 1:CAS:528:DC%2BD2sXovFeku7s%3D (Pubitemid 47255921)
44. V Morales T Straub MF Neumann G Mengus A Akhtar PB Becker 2004 Functional integration of the histone acetyltransferase MOF into the dosage compensation complex EMBO J 23 2258 2268 15141166 10.1038/sj.emboj.7600235 1:CAS:528:DC%2BD2cXksV2htr4%3D (Pubitemid 38833235)
45. A Buscaino T Kocher JH Kind H Holz M Taipale K Wagner M Wilm A Akhtar 2003 MOF-regulated acetylation of MSL-3 in the Drosophila dosage compensation complex Mol Cell 11 1265 1277 12769850 10.1016/S1097-2765(03)00140-0 1:CAS:528:DC%2BD3sXksVOjt7Y%3D (Pubitemid 36645145)
46. A Akhtar D Zink PB Becker 2000 Chromodomains are protein-RNA interaction modules Nature 407 405 409 11014199 10.1038/35030169 1:CAS:528: DC%2BD3cXntF2ntb4%3D
47. Y Cai J Jin SK Swanson MD Cole SH Choi L Florens MP Washburn JW Conaway RC Conaway 2010 Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex J Biol Chem 285 4268 4272 20018852 10.1074/jbc.C109.087981 1:CAS:528:DC%2BC3cXhs1altLk%3D
48. S Mendjan M Taipale J Kind H Holz P Gebhardt M Schelder M Vermeulen A Buscaino K Duncan J Mueller M Wilm HG Stunnenberg H Saumweber A Akhtar 2006 Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila Mol Cell 21 811 823 16543150 10.1016/j.molcel.2006. 02.007 1:CAS:528:DC%2BD28XjtVyju7s%3D (Pubitemid 43376131)
49. SM Sykes HS Mellert MA Holbert K Li R Marmorstein WS Lane SB McMahon 2006 Acetylation of the p53 DNA-binding domain regulates apoptosis induction Mol Cell 24 841 851 17189187 10.1016/j.molcel.2006.11.026 1:CAS:528: DC%2BD2sXmvVyqug%3D%3D (Pubitemid 44960096)
50. Y Tang J Luo W Zhang W Gu 2006 Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis Mol Cell 24 827 839 17189186 10.1016/j.molcel.2006.11.021 1:CAS:528:DC%2BD2sXmvVyqtQ%3D%3D (Pubitemid 44960094)
51. Y Zhou KM Schmitz C Mayer X Yuan A Akhtar I Grummt 2009 Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing Nat Cell Biol 11 1010 1016 19578370 10.1038/ncb1914 1:CAS:528:DC%2BD1MXpsVaktb4%3D
52. T Ikura S Tashiro A Kakino H Shima N Jacob R Amunugama K Yoder S Izumi I Kuraoka K Tanaka H Kimura M Ikura S Nishikubo T Ito A Muto K Miyagawa S Takeda R Fishel K Igarashi K Kamiya 2007 DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics Mol Cell Biol 27 7028 7040 17709392 10.1128/MCB.00579-07 1:CAS:528:DC%2BD2sXhtFKjsb7L (Pubitemid 47549742)
53. R Murr JI Loizou YG Yang C Cuenin H Li ZQ Wang Z Herceg 2006 Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks Nat Cell Biol 8 91 99 16341205 10.1038/ncb1343 1:CAS:528:DC%2BD28Xmt1eh (Pubitemid 43064802)
54. V Sapountzi IR Logan CN Robson 2006 Cellular functions of TIP60 Int J Biochem Cell Biol 38 1496 1509 16698308 10.1016/j.biocel.2006.03.003 1:CAS:528:DC%2BD28XkvVGjtrw%3D (Pubitemid 44250950)
55. S Jha E Shibata A Dutta 2008 Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage Mol Cell Biol 28 2690 2700 18285460 10.1128/MCB.01983-07 1:CAS:528:DC%2BD1cXksFWqtrk%3D (Pubitemid 351542368)
56. T Kusch L Florens WH Macdonald SK Swanson RL Glaser JR Yates III. SM Abmayr MP Washburn JL Workman 2004 Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions Science 306 2084 2087 15528408 10.1126/science.1103455 1:CAS:528:DC%2BD2cXhtVOjsLrJ (Pubitemid 40007658)
57. TG Fazzio JT Huff B Panning 2008 An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity Cell 134 162 174 18614019 10.1016/j.cell.2008.05.031 1:CAS:528:DC%2BD1cXoslyjtbw%3D (Pubitemid 351905738)
58. C Leduc P Claverie B Eymin E Col S Khochbin E Brambilla S Gazzeri 2006 p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation Oncogene 25 4147 4154 16501607 10.1038/sj.onc.1209446 1:CAS:528:DC%2BD28XmvFais74%3D (Pubitemid 44079448)
59. JH Patel Y Du PG Ard C Phillips B Carella CJ Chen C Rakowski C Chatterjee PM Lieberman WS Lane GA Blobel SB McMahon 2004 The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60 Mol Cell Biol 24 10826 10834 15572685 10.1128/MCB.24.24.10826-10834.2004 1:CAS:528:DC%2BD2cXhtFSgsr7L (Pubitemid 39603138)
60. F Faiola X Liu S Lo S Pan K Zhang E Lymar A Farina E Martinez 2005 Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription Mol Cell Biol 25 10220 10234 16287840 10.1128/MCB.25.23.10220-10234.2005 1:CAS:528:DC%2BD2MXht1Ons7fL (Pubitemid 41681950)
61. Y Doyon W Selleck WS Lane S Tan J Cote 2004 Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans Mol Cell Biol 24 1884 1896 14966270 10.1128/MCB.24.5.1884-1896.2004 1:CAS:528:DC%2BD2cXhvVWgt7o%3D (Pubitemid 38248930)
62. J Park S Kunjibettu SB McMahon MD Cole 2001 The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis Genes Dev 15 1619 1624 11445536 10.1101/gad.900101 1:CAS:528:DC%2BD3MXltFKqt7o%3D (Pubitemid 32702583)
63. SR Frank T Parisi S Taubert P Fernandez M Fuchs HM Chan DM Livingston B Amati 2003 MYC recruits the TIP60 histone acetyltransferase complex to chromatin EMBO Rep 4 575 580 12776177 10.1038/sj.embor.embor861 1:CAS:528: DC%2BD3sXktFOgtrY%3D (Pubitemid 36939948)
64. F Martinato M Cesaroni B Amati E Guccione 2008 Analysis of Myc-induced histone modifications on target chromatin PLoS One 3 e3650 18985155 10.1371/journal.pone.0003650
65. J Kim AJ Woo J Chu JW Snow Y Fujiwara CG Kim AB Cantor SH Orkin 2010 A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs Cell 143 313 324 20946988 10.1016/j.cell.2010.09.010 1:CAS:528:DC%2BC3cXht12qurbM
66. C Gorrini M Squatrito C Luise N Syed D Perna L Wark F Martinato D Sardella A Verrecchia S Bennett S Confalonieri M Cesaroni F Marchesi M Gasco E Scanziani M Capra S Mai P Nuciforo T Crook J Lough B Amati 2007 Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response Nature 448 1063 1067 17728759 10.1038/nature06055 1:CAS:528: DC%2BD2sXps12ns7c%3D (Pubitemid 47345581)
67. K Halkidou IR Logan S Cook DE Neal CN Robson 2004 Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription Nucleic Acids Res 32 1654 1665 15016909 10.1093/nar/gkh296 1:CAS:528: DC%2BD2cXisF2lu7g%3D (Pubitemid 38842408)
68. Y Sun X Jiang S Chen N Fernandes BD Price 2005 A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM Proc Natl Acad Sci USA 102 13182 13187 16141325 10.1073/pnas.0504211102 1:CAS:528:DC%2BD2MXhtVejsr7P (Pubitemid 41324998)
69. J Ning G Zheng YC Yang 2008 Tip60 modulates PLAGL2-mediated transactivation by acetylation J Cell Biochem 103 730 739 17551969 10.1002/jcb.21444 1:CAS:528:DC%2BD1cXit1Shsrw%3D (Pubitemid 351240610)
70. L Gaughan IR Logan S Cook DE Neal CN Robson 2002 Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor J Biol Chem 277 25904 25913 11994312 10.1074/jbc.M203423200 1:CAS:528:DC%2BD38XlsFKrsL4%3D (Pubitemid 34967070)
71. MY Kim EJ Ann JY Kim JS Mo JH Park SY Kim MS Seo HS Park 2007 Tip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylation Mol Cell Biol 27 6506 6519 17636029 10.1128/MCB.01515-06 1:CAS:528:DC%2BD2sXhtVKls7nL (Pubitemid 47435755)
72. SM Sykes TJ Stanek A Frank ME Murphy SB McMahon 2009 Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53 J Biol Chem 284 20197 20205 19494119 10.1074/jbc.M109.026096 1:CAS:528: DC%2BD1MXos1ensL8%3D
73. K Berns EM Hijmans J Mullenders TR Brummelkamp A Velds M Heimerikx RM Kerkhoven M Madiredjo W Nijkamp B Weigelt R Agami W Ge G Cavet PS Linsley RL Beijersbergen R Bernards 2004 A large-scale RNAi screen in human cells identifies new components of the p53 pathway Nature 428 431 437 15042092 10.1038/nature02371 1:CAS:528:DC%2BD2cXisVGlsLY%3D (Pubitemid 38419689)
74. G Legube LK Linares S Tyteca C Caron M Scheffner M Chevillard-Briet D Trouche 2004 Role of the histone acetyl transferase Tip60 in the p53 pathway J Biol Chem 279 44825 44833 15310756 10.1074/jbc.M407478200 1:CAS:528: DC%2BD2cXosFymtbg%3D (Pubitemid 39430894)
75. JK Kurash H Lei Q Shen WL Marston BW Granda H Fan D Wall E Li F Gaudet 2008 Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo Mol Cell 29 392 400 18280244 10.1016/j.molcel.2007.12.025 1:CAS:528: DC%2BD1cXisFSnsL4%3D (Pubitemid 351215939)
76. Y Sun Y Xu K Roy BD Price 2007 DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity Mol Cell Biol 27 8502 8509 17923702 10.1128/MCB.01382-07 1:CAS:528:DC%2BD1cXmt1eqtQ%3D%3D
77. JA Downs S Allard O Jobin-Robitaille A Javaheri A Auger N Bouchard SJ Kron SP Jackson J Cote 2004 Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites Mol Cell 16 979 990 15610740 10.1016/j.molcel.2004.12.003 1:CAS:528:DC%2BD2MXjvVWjtA%3D%3D (Pubitemid 40018407)
78. AA Boudreault D Cronier W Selleck N Lacoste RT Utley S Allard J Savard WS Lane S Tan J Cote 2003 Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin Genes Dev 17 1415 1428 12782659 10.1101/gad.1056603 1:CAS:528:DC%2BD3sXksFehsbo%3D (Pubitemid 36666010)
79. PY Lu N Levesque MS Kobor 2009 NuA4 and SWR1-C: two chromatin-modifying complexes with overlapping functions and components Biochem Cell Biol 87 799 815 19898529 10.1139/O09-062 1:CAS:528:DC%2BD1MXht1antL7L
80. Y Doyon J Cote 2004 The highly conserved and multifunctional NuA4 HAT complex Curr Opin Genet Dev 14 147 154 15196461 10.1016/j.gde.2004.02.009 1:CAS:528:DC%2BD2cXivVKktLs%3D (Pubitemid 38520142)
81. M Altaf A Auger M Covic J Cote 2009 Connection between histone H2A variants and chromatin remodeling complexes Biochem Cell Biol 87 35 50 19234522 10.1139/O08-140 1:CAS:528:DC%2BD1MXit1agt78%3D
82. SM Hoke J Guzzo B Andrews CJ Brandl 2008 Systematic genetic array analysis links the Saccharomyces cerevisiae SAGA/SLIK and NuA4 component Tra1 to multiple cellular processes BMC Genet 9 46 18616809 10.1186/1471-2156-9-46
83. L Mitchell JP Lambert M Gerdes AS Al-Madhoun IS Skerjanc D Figeys K Baetz 2008 Functional dissection of the NuA4 histone acetyltransferase reveals its role as a genetic hub and that Eaf1 is essential for complex integrity Mol Cell Biol 28 2244 2256 18212056 10.1128/MCB.01653-07 1:CAS:528:DC%2BD1cXjvFemtL0%3D (Pubitemid 351429971)
84. YY Lin Y Qi JY Lu X Pan DS Yuan Y Zhao JS Bader JD Boeke 2008 A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation Genes Dev 22 2062 2074 18676811 10.1101/gad.1679508 1:CAS:528:DC%2BD1cXpslKqsbo%3D
85. MC Scrutton FU Utter 1968 The regulation of glycolysis and gluconeogenesis in animal tissues Annu Rev Biochem 37 249 302 10.1146/annurev.bi.37.070168.001341 1:CAS:528:DyaF1MXjsVajtA%3D%3D
86. P Fabrizio C Gattazzo L Battistella M Wei C Cheng K McGrew VD Longo 2005 Sir2 blocks extreme life-span extension Cell 123 655 667 16286010 10.1016/j.cell.2005.08.042 1:CAS:528:DC%2BD2MXht1yktrjP (Pubitemid 41608467)
87. M Kaeberlein M McVey L Guarente 1999 The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms Genes Dev 13 2570 2580 10521401 10.1101/gad.13.19.2570 1:CAS:528:DyaK1MXmvFOitbc%3D (Pubitemid 29489648)
88. T Kouzarides 2000 Acetylation: a regulatory modification to rival phosphorylation? EMBO J 19 1176 1179 10716917 10.1093/emboj/19.6.1176 1:CAS:528:DC%2BD3cXit1Gms7o%3D (Pubitemid 30151013)
89. VJ Starai I Celic RN Cole JD Boeke JC Escalante-Semerena 2002 Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine Science 298 2390 2392 12493915 10.1126/science.1077650 1:CAS:528:DC%2BD38Xps1Sju70%3D (Pubitemid 36014212)
90. H Takahashi JM McCaffery RA Irizarry JD Boeke 2006 Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription Mol Cell 23 207 217 16857587 10.1016/j.molcel.2006.05.040 1:CAS:528:DC%2BD28XotVCjurk%3D (Pubitemid 44081880)
91. KE Wellen G Hatzivassiliou UM Sachdeva TV Bui JR Cross CB Thompson 2009 ATP-citrate lyase links cellular metabolism to histone acetylation Science 324 1076 1080 19461003 10.1126/science.1164097 1:CAS:528:DC%2BD1MXmtVKlsb8%3D
92. Q Wang Y Zhang C Yang H Xiong Y Lin J Yao H Li L Xie W Zhao Y Yao ZB Ning R Zeng Y Xiong KL Guan S Zhao GP Zhao 2010 Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux Science 327 1004 1007 20167787 10.1126/science.1179687 1:CAS:528:DC%2BC3cXitVSjtbs%3D
93. RM Friis BP Wu SN Reinke DJ Hockman BD Sykes MC Schultz 2009 A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA Nucleic Acids Res 37 3969 3980 19406923 10.1093/nar/gkp270 1:CAS:528:DC%2BD1MXovVektLs%3D
94. Y Yan S Harper DW Speicher R Marmorstein 2002 The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate Nat Struct Biol 9 862 869 12368900 10.1038/nsb0902-638 1:CAS:528: DC%2BD38XosFCjsLk%3D (Pubitemid 34977291)
95. CE Berndsen BN Albaugh S Tan JM Denu 2007 Catalytic mechanism of a MYST family histone acetyltransferase Biochemistry 46 623 629 17223684 10.1021/bi602513x 1:CAS:528:DC%2BD28XhtlCgs7zM (Pubitemid 46133582)
96. J Wang J Chen 2010 SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60 J Biol Chem 285 11458 11464 20100829 10.1074/jbc.M109.087585 1:CAS:528:DC%2BC3cXktFGlt74%3D
97. N Avvakumov J Cote 2007 Functions of myst family histone acetyltransferases and their link to disease Subcell Biochem 41 295 317 17484133