Cytotoxicity, apoptosis-inducing effects and structure-activity relationships of four natural xanthones from Gentianopsis paludosa Ma in HepG2 and HL-60 cells

Natural Product Research

Volumn 25, Issue 7, 2011, Pages 669-683

  Ding, Lan ^a   Liu, Bo ^a   Zhang, Shi Dong ^a   Hou, Qian ^a   Qi, Lin Lin ^a   Zhou, Qi Yin ^a  

^a NORTHWEST NORMAL UNIVERSITY   (China)

Author keywords

anticancer; apoptosis; cytotoxic; Gentianopsis paludosa Ma; xanthones

Indexed keywords

1 HYDROXY 3,7,8 TRIMETHOXYXANTHON; 1 O BETA DEXTRO GLUCOSIDE 7 HYDROXYL 3,8 DIMETHOXYXANTHONE; 1,7 DIHYDROXY 3,8 DIMETHOXYXANTHONE; 1,8 DIHYDROXY 3,7 DIMETHOXYXANTHONE; ANTINEOPLASTIC AGENT; DNA FRAGMENT; FUNCTIONAL GROUP; HYDROXYL GROUP; METHOXY GROUP; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL STRAIN HL 60; CELL STRUCTURE; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; FLOW CYTOMETRY; GENTIANACEAE; GENTIANOPSIS PALUDOSA; HUMAN; HUMAN CELL; IC 50; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; GENTIANACEAE; GLUCOSIDES; HL-60 CELLS; HUMANS; PLANT EXTRACTS; PLANTS, MEDICINAL; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHONES;

GENTIANOPSIS PALUDOSA;

EID: 79953701647     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786410802497398     Document Type: Article

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